In many reactions involving selenosulfonate or thiosulfonate,the sutfone group often leaves in form of benzenesutfinic acid or sodium benzenesulfinate.A one-pot two-step reaction of selenosulfonate with isocyanides an...In many reactions involving selenosulfonate or thiosulfonate,the sutfone group often leaves in form of benzenesutfinic acid or sodium benzenesulfinate.A one-pot two-step reaction of selenosulfonate with isocyanides and allyl alcohol under aqueous conditions to afford selenocarbamates and allyl sulfone compounds is reported.The sulfinic acid as the first-step side product is converted to the allyl sulfone compound by water promoted reaction with allyl alcohol.Water acts as both an oxygen source of selenocarbamates and as a promoter to drive the second step reactio n.The reactions have the advantages of mild conditions,green,environment-friendly,and high atomic economy.展开更多
An efficient palladium-catalyzed sulfonylative coupling for the synthesis of benzyl(allyl)sulfones from sulfonyl hydrazides and carbonates was developed.The novel methodology employs easily accessible chemical feedsto...An efficient palladium-catalyzed sulfonylative coupling for the synthesis of benzyl(allyl)sulfones from sulfonyl hydrazides and carbonates was developed.The novel methodology employs easily accessible chemical feedstocks including stable and readily available arylsulfonyl hydrazides and benzyl(allyl)carbonates.A variety of benzyl(allyl)sulfones could be obtained in good to excellent yields in the presence of Pd(dppf)Cl2 without additional base under mild conditions.展开更多
基金the National Natural Science Foundation of China (Nos.21971174,21772137,21672157)the Ph.D.Programs Foundation of PAPD+2 种基金the Project of Scientific and Technologic Infrastructure of Suzhou (No.SZS201708)the Major Basic Research Project of the Natural Science Foundation of the Jiangsu Higher Education Institutions (No. 16KJA150002)Soochow University,and State and Local Joint Engineering Laboratory for Novel Functional Polymeric Materials for financial support。
文摘In many reactions involving selenosulfonate or thiosulfonate,the sutfone group often leaves in form of benzenesutfinic acid or sodium benzenesulfinate.A one-pot two-step reaction of selenosulfonate with isocyanides and allyl alcohol under aqueous conditions to afford selenocarbamates and allyl sulfone compounds is reported.The sulfinic acid as the first-step side product is converted to the allyl sulfone compound by water promoted reaction with allyl alcohol.Water acts as both an oxygen source of selenocarbamates and as a promoter to drive the second step reactio n.The reactions have the advantages of mild conditions,green,environment-friendly,and high atomic economy.
基金We gratefully acknowledge the National Natural Science Foundation of China(Nos.21801040,22008028,22102022)the Natural Science Foundation of Jiangxi Province(Nos.20192BAB213006,20181BBH80007)+1 种基金the Opening Project of Jiangxi Province Key Laboratory of Polymer Micro/Nano Manufacturing and Devices(Nos.PMND202001,PMND202003)East China University of Technology Research Foundation for Advanced Talents(No.DHBK2017168)provides financial support.
文摘An efficient palladium-catalyzed sulfonylative coupling for the synthesis of benzyl(allyl)sulfones from sulfonyl hydrazides and carbonates was developed.The novel methodology employs easily accessible chemical feedstocks including stable and readily available arylsulfonyl hydrazides and benzyl(allyl)carbonates.A variety of benzyl(allyl)sulfones could be obtained in good to excellent yields in the presence of Pd(dppf)Cl2 without additional base under mild conditions.
