Objective： To assess the effects of treatment of Amanita mushroom poisoning with Glossy anoderma Decoction （灵芝煎剂, GGD）. Methods： Twelve patients with acute Amanita mushroom poisoning received conventional trea...Objective： To assess the effects of treatment of Amanita mushroom poisoning with Glossy anoderma Decoction （灵芝煎剂, GGD）. Methods： Twelve patients with acute Amanita mushroom poisoning received conventional treatment （penicillin and reduced glutathione） combined with oral administration of GGD （treated group）, which was prepared out of 200 g Glossy ganoderma decocted in water to 600 mL, and 200 ml was given once, three times a day for 7 successive days; while conventional treatment alone was given to the other 11 patients assigned to the control group. The therapeutic efficacy and changes in serum levels of total bilirubin （TBil）, bile acids （BA）, alanine transaminase （ALl-）, and aspartate transaminase （AST） activities in the two groups were compared. Results： The cured- markedly effective rate in the treated group was more significant than that in the control group （P〈0.01）. Elevation in TBil, BA, ALT, and AST activities were observed in both groups 3 days after poisoning, which progressively increased thereafter in the control group. In the treated group, they reached their peak on the 3rd day and then declined gradually. The differences between pre-treatment and post-treatment in both groups were obviously significant （P〈0.01）, so were the differences between the two groups at corresponding time points （P〈0.01）. Conclusion： GGD shows excellent clinical efficacy in the treatment of acute Amanita mushroom poisoning and can reduce mortality significantly.展开更多
Deadly poisonous amanitae are common and widely distributed in China.They cause dramatic poisonings or even deaths every year.The well-known lethal mushrooms Amanita phalloides,A.verna and A.virosa,all originally desc...Deadly poisonous amanitae are common and widely distributed in China.They cause dramatic poisonings or even deaths every year.The well-known lethal mushrooms Amanita phalloides,A.verna and A.virosa,all originally described from Europe,were repeatedly reported from China,but no reliable record can be confirmed.However,other lethal mushrooms,i.e.A. exitialis,A.fuliginea,A.oberwinklerana,A.subjunquillea var.subjunquillea,and A.subjunquillea var.alba can frequently be found in various forests in China.Amanita fuliginea may easily be confused with A.manginiana sensu Chiu and A.yuaniana,both of which are favorable wild edible mushrooms in southwestern China.Moreover,the edible mushroom A.chepangiana may be mixed up with A.exitialis,A.oberwinklerana,and A.subjunquillea var.alba.A key to the Chinese taxa of Amanita mentioned above is provided.展开更多
基金Supported by the Funds from Hunan Provincial Administration of Traditional Chinese Medicine (No 204054)
文摘Objective： To assess the effects of treatment of Amanita mushroom poisoning with Glossy anoderma Decoction （灵芝煎剂, GGD）. Methods： Twelve patients with acute Amanita mushroom poisoning received conventional treatment （penicillin and reduced glutathione） combined with oral administration of GGD （treated group）, which was prepared out of 200 g Glossy ganoderma decocted in water to 600 mL, and 200 ml was given once, three times a day for 7 successive days; while conventional treatment alone was given to the other 11 patients assigned to the control group. The therapeutic efficacy and changes in serum levels of total bilirubin （TBil）, bile acids （BA）, alanine transaminase （ALl-）, and aspartate transaminase （AST） activities in the two groups were compared. Results： The cured- markedly effective rate in the treated group was more significant than that in the control group （P〈0.01）. Elevation in TBil, BA, ALT, and AST activities were observed in both groups 3 days after poisoning, which progressively increased thereafter in the control group. In the treated group, they reached their peak on the 3rd day and then declined gradually. The differences between pre-treatment and post-treatment in both groups were obviously significant （P〈0.01）, so were the differences between the two groups at corresponding time points （P〈0.01）. Conclusion： GGD shows excellent clinical efficacy in the treatment of acute Amanita mushroom poisoning and can reduce mortality significantly.
基金国家自然科学基金 (No . 3980 0 0 0 7)云南省自然科学基金 (No . 98Co2 6Q)资助项目
文摘Deadly poisonous amanitae are common and widely distributed in China.They cause dramatic poisonings or even deaths every year.The well-known lethal mushrooms Amanita phalloides,A.verna and A.virosa,all originally described from Europe,were repeatedly reported from China,but no reliable record can be confirmed.However,other lethal mushrooms,i.e.A. exitialis,A.fuliginea,A.oberwinklerana,A.subjunquillea var.subjunquillea,and A.subjunquillea var.alba can frequently be found in various forests in China.Amanita fuliginea may easily be confused with A.manginiana sensu Chiu and A.yuaniana,both of which are favorable wild edible mushrooms in southwestern China.Moreover,the edible mushroom A.chepangiana may be mixed up with A.exitialis,A.oberwinklerana,and A.subjunquillea var.alba.A key to the Chinese taxa of Amanita mentioned above is provided.
