Aminochlorination of methylenecyclopropanes （MCPs） 1 can be achieved under CO2 atmosphere using N,N-dichlorotoluenesulfonamine （TsNCl2） as the nitrogen and halogen sources at room temperature to give the correspon...Aminochlorination of methylenecyclopropanes （MCPs） 1 can be achieved under CO2 atmosphere using N,N-dichlorotoluenesulfonamine （TsNCl2） as the nitrogen and halogen sources at room temperature to give the corresponding normal ring-remaining aminochlorinated products 2 along with/without the ring-opened aminochlorinated products 3 in moderate to good total yields. The present process takes the advantage of the green benign reaction conditions in the absence of any metal catalyst and solvent.展开更多
基金Project supported by Shanghai Municipal Committee of Science and Technology （No. 08dj1400100-2）, National Basic Research Program of China （973） （No. 2009CB825300） and the National Natural Science Foundation of China （Nos. 21072206, 20472096, 20872162, 20672127, 20821002 and 20732008）.
文摘Aminochlorination of methylenecyclopropanes （MCPs） 1 can be achieved under CO2 atmosphere using N,N-dichlorotoluenesulfonamine （TsNCl2） as the nitrogen and halogen sources at room temperature to give the corresponding normal ring-remaining aminochlorinated products 2 along with/without the ring-opened aminochlorinated products 3 in moderate to good total yields. The present process takes the advantage of the green benign reaction conditions in the absence of any metal catalyst and solvent.
