This study investigated the important factors that affect the operating parameters of thermally regenerative ammoniabased batteries(TRABs),including the metal electrode type,membrane type,electrode surface area,electr...This study investigated the important factors that affect the operating parameters of thermally regenerative ammoniabased batteries(TRABs),including the metal electrode type,membrane type,electrode surface area,electrode distance,electrolyte concentration,and ammonia concentration.The experimental results showed that the maximum power density of TRABs with a Cu electrode was 40.0 W·m^(2),which was considerably higher than that with Ni(0.34 W·m^(2))and Co(0.14 W·m^(2))electrodes.TRABs with an anion exchange membrane had a 28.6%higher maximum power density than those with a cation exchange membrane.An increased electrode surface resulted in an increased maximum power but a decreased maximum power density.Within a certain range,TRAB performance was enhanced with decreased electrode distance and increased electrolyte concentration.An increased ammonia concentration resulted in enhanced ammonia transfer and improved the TRAB performance.展开更多
Background:Non-small cell lung cancer(NSCLC)has a poor prognosis with a low 5-year survival rate.Lung adenocarcinoma(LUAD)accounts for 50%.Facio-genital dysplasia-5(FGD5),a member of a subfamily of Rho GTPGDP exchange...Background:Non-small cell lung cancer(NSCLC)has a poor prognosis with a low 5-year survival rate.Lung adenocarcinoma(LUAD)accounts for 50%.Facio-genital dysplasia-5(FGD5),a member of a subfamily of Rho GTPGDP exchange factors,may be a good molecular biomarker for diagnosis and prognosis.Objective:To explore the clinical application of FGD5,the study was designed to investigate the prognosis value of FGD5 expression and its correlation with immune infiltrates in LUAD patients.Methods:Through the Wilcoxon signed-rank test and logistic regression,the correlation between clinical characteristics and FGD5 expression was analyzed.Kaplan-Meier plotter analysis,Cox regression,and a receiver operating characteristic(ROC)curve were constructed to evaluate the influence of FGD5 on prognosis.The function of FGD5 in lung cancer was analyzed using Gene set enrichment analysis(GSEA)and Single Sample Gene Set Enrichment Analysis(ssGSEA).Results:Compared to normal tissues,FGD5 was downregulated in LUAD.FGD5 may be a potential diagnostic and prognostic biomarker of lung cancer for its association with improved overall survival(OS),progression-free interval(PFI),and disease-specific survival(DSS)in LUAD.Results of functional analysis suggested that FGD5 was involved in the immune response for its association with immune infiltration.Conclusion:FGD5 may be a significant molecular biomarker for diagnosis and prognosis,presenting as an independent prognostic risk factor for LUAD.展开更多
基金the National Natural Science Foundation of China(No.51976018)the National Natural Science Foundation for Young Scientists of China(No.51606022)+3 种基金Natural Science Foundation of Chongqing,China(No.cstc2017jcyjAX0203)Scientific Research Foundation for Returned Overseas Chinese Scholars of Chongqing,China(No.cx2017020)the Fundamental Research Funds for the Central Universities(No.106112016CDJXY145504)Research Funds of Key Laboratory of Low-grade Energy Utilization Technologies and Systems(No.LLEUTS-2018005).
文摘This study investigated the important factors that affect the operating parameters of thermally regenerative ammoniabased batteries(TRABs),including the metal electrode type,membrane type,electrode surface area,electrode distance,electrolyte concentration,and ammonia concentration.The experimental results showed that the maximum power density of TRABs with a Cu electrode was 40.0 W·m^(2),which was considerably higher than that with Ni(0.34 W·m^(2))and Co(0.14 W·m^(2))electrodes.TRABs with an anion exchange membrane had a 28.6%higher maximum power density than those with a cation exchange membrane.An increased electrode surface resulted in an increased maximum power but a decreased maximum power density.Within a certain range,TRAB performance was enhanced with decreased electrode distance and increased electrolyte concentration.An increased ammonia concentration resulted in enhanced ammonia transfer and improved the TRAB performance.
文摘Background:Non-small cell lung cancer(NSCLC)has a poor prognosis with a low 5-year survival rate.Lung adenocarcinoma(LUAD)accounts for 50%.Facio-genital dysplasia-5(FGD5),a member of a subfamily of Rho GTPGDP exchange factors,may be a good molecular biomarker for diagnosis and prognosis.Objective:To explore the clinical application of FGD5,the study was designed to investigate the prognosis value of FGD5 expression and its correlation with immune infiltrates in LUAD patients.Methods:Through the Wilcoxon signed-rank test and logistic regression,the correlation between clinical characteristics and FGD5 expression was analyzed.Kaplan-Meier plotter analysis,Cox regression,and a receiver operating characteristic(ROC)curve were constructed to evaluate the influence of FGD5 on prognosis.The function of FGD5 in lung cancer was analyzed using Gene set enrichment analysis(GSEA)and Single Sample Gene Set Enrichment Analysis(ssGSEA).Results:Compared to normal tissues,FGD5 was downregulated in LUAD.FGD5 may be a potential diagnostic and prognostic biomarker of lung cancer for its association with improved overall survival(OS),progression-free interval(PFI),and disease-specific survival(DSS)in LUAD.Results of functional analysis suggested that FGD5 was involved in the immune response for its association with immune infiltration.Conclusion:FGD5 may be a significant molecular biomarker for diagnosis and prognosis,presenting as an independent prognostic risk factor for LUAD.
