AIM：To define the financial and management conditions required to introduce a femtosecond laser system for cataract surgery in a clinic using a fuzzy logic approach.METHODS：In the simulation performed in the current...AIM：To define the financial and management conditions required to introduce a femtosecond laser system for cataract surgery in a clinic using a fuzzy logic approach.METHODS：In the simulation performed in the current study,the costs associated to the acquisition and use of a commercially available femtosecond laser platform for cataract surgery（VICTUS,TECHNOLAS Perfect Vision GmbH,Bausch ＆ Lomb,Munich,Germany） during a period of 5y were considered.A sensitivity analysis was performed considering such costs and the countable amortization of the system during this 5y period.Furthermore,a fuzzy logic analysis was used to obtain an estimation of the money income associated to each femtosecond laser-assisted cataract surgery（G）. RESULTS：According to the sensitivity analysis,the femtosecond laser system under evaluation can be profitable if 1400 cataract surgeries are performed per year and if each surgery can be invoiced more than $500.In contrast,the fuzzy logic analysis confirmed that the patient had to pay more per surgery,between $661.8 and $667.4 per surgery,without considering the cost of the intraocular lens（IOL）.CONCLUSION：A profitability of femtosecond laser systems for cataract surgery can be obtained after a detailed financial analysis,especially in those centers with large volumes of patients.The cost of the surgery for patients should be adapted to the real flow of patients with the ability of paying a reasonable range of cost.展开更多
The article discusses the problem of the unity of Ludwig Wittgenstein＇s philosophy. It is demonstrated that Wittgenstein applied two methods of study. Changes in his philosophy are correlated with modifications in hi...The article discusses the problem of the unity of Ludwig Wittgenstein＇s philosophy. It is demonstrated that Wittgenstein applied two methods of study. Changes in his philosophy are correlated with modifications in his method of thinking and investigation. In his Tractatus Logico-Philosophicus, the only correct method is logical proposition analysis. In the early 1930s, he transformed his philosophy into a phenomenological description of experience, defining its aim as the development of phenomenological language. After 1933, Wittgenstein recognised the grammatical dimension of language and created tools of grammatical analysis. He introduced the notions of language-games and life forms. His philosophy turned into morphology and a description of human language practice.展开更多
The reverse construction and analysis of the networks of molecular interactions are essential for understanding their functions within cells. In this paper, a logic network model is constructed to investigate the comp...The reverse construction and analysis of the networks of molecular interactions are essential for understanding their functions within cells. In this paper, a logic network model is constructed to investigate the complicated regulation mechanism of shoot genes of Arabidopsis Thaliana in response to stimuli. The dynamics of the complicated logic network is analyzed, discussed, and simulated. The simulation results show that the logic network of the active genes of shoot eventually evolves into eleven attractors under the stimuli, including five 1-periodic and six 2-periodic attractors. Our work provides valuable reference and guidance for biologists to understand and explain Arabidopsis＇ response to external stimuli by experiments.展开更多
Considered from a logical point of view,Confucius'Analects contain many implicit forms of reasoning and argumentation.This is shown first by analyzing the phenomenon of parallelism:direct parallelism is often a wa...Considered from a logical point of view,Confucius'Analects contain many implicit forms of reasoning and argumentation.This is shown first by analyzing the phenomenon of parallelism:direct parallelism is often a way of hinting at a general assertion,whereas anti-parallelism hides dilemmas,generalizations and modal notions of"moral preference."The Analects also have various types of conditionals,ranging from material implications,to modalized implications,and counterfactual conditionals,which are the germs of implicit reasoning,concluding with a moral recommendation.Analogies are particularly abundant and a presentation of three examples suggests that,beyond their explicative role,they also involve moral recommendations.The implicit logic of The Analects requires an active,albeit unconscious participation of the reader,which could be an important element in explaining the enduring influence of the text.展开更多
文摘AIM：To define the financial and management conditions required to introduce a femtosecond laser system for cataract surgery in a clinic using a fuzzy logic approach.METHODS：In the simulation performed in the current study,the costs associated to the acquisition and use of a commercially available femtosecond laser platform for cataract surgery（VICTUS,TECHNOLAS Perfect Vision GmbH,Bausch ＆ Lomb,Munich,Germany） during a period of 5y were considered.A sensitivity analysis was performed considering such costs and the countable amortization of the system during this 5y period.Furthermore,a fuzzy logic analysis was used to obtain an estimation of the money income associated to each femtosecond laser-assisted cataract surgery（G）. RESULTS：According to the sensitivity analysis,the femtosecond laser system under evaluation can be profitable if 1400 cataract surgeries are performed per year and if each surgery can be invoiced more than $500.In contrast,the fuzzy logic analysis confirmed that the patient had to pay more per surgery,between $661.8 and $667.4 per surgery,without considering the cost of the intraocular lens（IOL）.CONCLUSION：A profitability of femtosecond laser systems for cataract surgery can be obtained after a detailed financial analysis,especially in those centers with large volumes of patients.The cost of the surgery for patients should be adapted to the real flow of patients with the ability of paying a reasonable range of cost.
文摘The article discusses the problem of the unity of Ludwig Wittgenstein＇s philosophy. It is demonstrated that Wittgenstein applied two methods of study. Changes in his philosophy are correlated with modifications in his method of thinking and investigation. In his Tractatus Logico-Philosophicus, the only correct method is logical proposition analysis. In the early 1930s, he transformed his philosophy into a phenomenological description of experience, defining its aim as the development of phenomenological language. After 1933, Wittgenstein recognised the grammatical dimension of language and created tools of grammatical analysis. He introduced the notions of language-games and life forms. His philosophy turned into morphology and a description of human language practice.
基金This research is supported by the National Natural Science Foundation of China under Grant Nos. 60874036 and 60503002.
文摘The reverse construction and analysis of the networks of molecular interactions are essential for understanding their functions within cells. In this paper, a logic network model is constructed to investigate the complicated regulation mechanism of shoot genes of Arabidopsis Thaliana in response to stimuli. The dynamics of the complicated logic network is analyzed, discussed, and simulated. The simulation results show that the logic network of the active genes of shoot eventually evolves into eleven attractors under the stimuli, including five 1-periodic and six 2-periodic attractors. Our work provides valuable reference and guidance for biologists to understand and explain Arabidopsis＇ response to external stimuli by experiments.
文摘Considered from a logical point of view,Confucius'Analects contain many implicit forms of reasoning and argumentation.This is shown first by analyzing the phenomenon of parallelism:direct parallelism is often a way of hinting at a general assertion,whereas anti-parallelism hides dilemmas,generalizations and modal notions of"moral preference."The Analects also have various types of conditionals,ranging from material implications,to modalized implications,and counterfactual conditionals,which are the germs of implicit reasoning,concluding with a moral recommendation.Analogies are particularly abundant and a presentation of three examples suggests that,beyond their explicative role,they also involve moral recommendations.The implicit logic of The Analects requires an active,albeit unconscious participation of the reader,which could be an important element in explaining the enduring influence of the text.
