Qualitative analysis of aromatic compounds via 1D TOCSY techniques

The aromatic compounds,including o-xylene,m-xylene,p-xylene,and ethylbenzene,primarily originate from the catalytic reforming of crude oil,and have a wide variety of applications.However,because of similar physical and chemical properties,these compounds are difficult to be identified by gas chromatography(GC)without standard samples.With the development of modern nuclear magnetic resonance(NMR)techniques,NMR has emerged as a powerful and efficient tool for the rapid analysis of complex and crude mixtures without purification.In this study,the parameters of one-dimensional(1D)total correlation spectroscopy(TOCSY)NMR techniques,including 1D selective gradient TOCSY and 1D chemicalshift-selective filtration(CSSF)with TOCSY,were optimized to obtain comprehensive molecular structure information.The results indicate that the overlapped signals in NMR spectra of nonpolar aromatic compounds(including o-xylene,m-xylene,p-xylene and ethylbenzene),polar aromatic compounds(benzyl alcohol,benzaldehyde,benzoic acid),and aromatic compounds with additional conjugated bonds(styrene)can be resolved in 1D TOCSY.More importantly,full molecular structures can be clearly distinguished by setting appropriate mixing time in 1D TOCSY.This approach simplifies the NMR spectra,provides structural information of entire molecules,and can be applied for the analysis of other structural isomers.

Qualitative and Quantitative Analysis of Alkaloids in Cortex Phellodendri by HPLC-ESI-MS/MS and HPLC-DAD

A combined method of high performance liquid chromatograph-elecrtrospray-ionization mass spectrometer（HPLC-ESI-MS/MS） coupled with a photodiode array detector（HPLC-DAD） and principal component analysis（PCA） was applied to the qualitative and quantitative analyses of alkaloids in Cortex Phellodendri（CP） samples, and to the differentiation of two species of CP, Cortex Phellodendri Chinensis（CPC） and Cortex Phellodendri Amurensis（CPA）. Twenty-two peaks appeared in the HPLC-MS base peak chromatogram of CP detected by the HPLC-ESI-MS/MS analysis, and the alkaloids were identified according to the MSn data, the known MS fragmentation rules and the literature data. Five alkaloids including berberine, palmatine, jatrorrhizine, phellodendrine and magnoflorine were simultaneously determinated by the HPLC-DAD. Berberine was the primary component in all CP samples, and the contents of berberine and palmatine were exploited to be two critical parameters for effective discrimination between the two species of CP. The average content of berberine in CPC（58.75 mg/g） was higher than that in CPA（9.16 mg/g）, while the content of palmatine was less, only 0.25 mg/g in CPC and 4.19 mg/g in CPA. With the use of PCA, samples datasets were separated successfully into two different clusters corresponding to the two species, and berberine, pahnatine, phellodendrine and magnoflorine contribute most to the above mentioned calssifying . The proposed method oroved to be a useful tool in the aualitv control of Chinese herbal medicines.

Signed Directed Graph and Qualitative Trend Analysis Based Fault Diagnosis in Chemical Industry

In the past 30 years,signed directed graph(SDG) ,one of the qualitative simulation technologies,has been widely applied for chemical fault diagnosis.However,SDG based fault diagnosis,as any other qualitative method,has poor diagnostic resolution.In this paper,a new method that combines SDG with qualitative trend analysis(QTA) is presented to improve the resolution.In the method,a bidirectional inference algorithm based on assumption and verification is used to find all the possible fault causes and their corresponding consistent paths in the SDG model.Then an improved QTA algorithm is used to extract and analyze the trends of nodes on the consis-tent paths found in the previous step.New consistency rules based on qualitative trends are used to find the real causes from the candidate causes.The resolution can be improved.This method combines the completeness feature of SDG with the good diagnostic resolution feature of QTA.The implementation of SDG-QTA based fault diagno-sis is done using the integrated SDG modeling,inference and post-processing software platform.Its application is illustrated on an atmospheric distillation tower unit of a simulation platform.The result shows its good applicability and efficiency.

Qualitative and Quantitative Analysis of Linoleic Acid in Polygonati Rhizoma

Objective To explore the major compound in Polygonati Rhizoma(Huang Jing,黄精)for quality control.Methods The major compound was isolated and analyzed by liquid chromatography-mass spectrometry(LC-MS),and subsequently further identified by nuclear magnetic resonance(NMR).Thin layer chromatography(TLC)was optimized based on the previous methods reported in the Chinese Pharmacopeia(2015 edition).Results The major compound was isolated from the natural material and identified as linoleic acid.A high performance liquid chromatography(HPLC)method with robust linearity(R2=0.9997),specificity,precision,stability,repeatability and recovery was developed for linoleic acid determination.TLC chromatogram was improved significantly after optimization for qualitative analysis.Conclusions The optimized TLC method is practical and can be adopted for quality control of Polygonati Rhizoma(Huang Jing,黄精).The levels of linoleic acid vary between species of Polygonati Rhizoma(Huang Jing,黄精),with Polygonatum cyrtonema Hua(Jiang Xing Huang Jing,姜型黄精)showing the highest contents.This study provides valuable information for quality control of Polygonati Rhizoma(Huang Jing,黄精).

Analysis on the Configuration Path of Improving the Quality and Efficiency of County-Level Libraries in China

County-level libraries have an inescapable responsibility for cultivating local cultural identity and realizing rural revitalization.Therefore,we analyzed factors that afect the service fficiency of gass-1oots libraries in Henan Province through a field investigation and qualitative comparative analysis(QCA),and proposed a higlh-efficiency configuration.In addition,we put forward the strategy of improving the quality and efficiency of our country's county-level libraries in the electonic information age.

Novel Investigation of Stochastic Fractional Differential Equations Measles Model via the White Noise and Global Derivative Operator Depending on Mittag-Leffler Kernel

Because of the features involved with their varied kernels,differential operators relying on convolution formulations have been acknowledged as effective mathematical resources for modeling real-world issues.In this paper,we constructed a stochastic fractional framework of measles spreading mechanisms with dual medication immunization considering the exponential decay and Mittag-Leffler kernels.In this approach,the overall population was separated into five cohorts.Furthermore,the descriptive behavior of the system was investigated,including prerequisites for the positivity of solutions,invariant domain of the solution,presence and stability of equilibrium points,and sensitivity analysis.We included a stochastic element in every cohort and employed linear growth and Lipschitz criteria to show the existence and uniqueness of solutions.Several numerical simulations for various fractional orders and randomization intensities are illustrated.

Green transformation paths of resource-based cities in China from the configuration perspective

Green transformation is an unavoidable choice for resource-based cities(RBCs)that face resource depletion and environmental pollution.Existing research has focused primarily on specific RBCs,making it challenging to apply green transformation strategies universally across cities.The fuzzy set qualitative comparative analysis(fsQCA)is a combination of qualitative and quantitative analyses that can handle multiple concurrent causality problems and determine how different conditions combine into configurations and generate an outcome.Thus,to address this gap,in this study,we established a research framework for green transformation and utilized the fsQCA to examine the configurations of 113 RBCs in China.By incorporating the element of time,this study explored the dynamic evolution of solutions in 2013,2016,and 2019.The main findings indicate that individual elements do not constitute the necessary conditions for improving the green transformation efficiency(GTE),and the systematic combination of multiple conditions is an effective path for realizing the improvement of the GTE in RBCs.Green transformation paths of RBCs exhibit the same destination through different paths.Additionally,the combination of system environment elements and system structure elements is both complementary and alternative.Differences in RBCs have led to various factor combinations and development paths,but there are some similarities in the key elements of the factor combinations at different stages.Economic environment,government support,and technological innovation are key factors that universally enhance the GTE in RBCs.These insights can assist city managers in formulating policies to drive green transformation and contribute to a better theoretical understanding of green transformation paths in RBCs.

Generation Mechanism and Social Impact of Knowledge in the Era of"New Quality Productivity"

The changes in knowledge forms in the era of"new quality productivity"are closely related to the development of society.With the rise of the Internet,"the world of dataism is coming".The traditional knowledge production model is undergoing fundamental changes in structure and nature.The most prominent change is that knowledge is becoming increasingly inseparable from data networks.The collaborative production of knowledge based on the Internet is becoming increasingly common,and Wikipedia is a prominent example of this.Wikipedia makes the networked production of knowledge possible by utilizing collective intelligence and data connectivity.Wiki users are commonly referred to as"wiki".This paper conducted interviews with 30 Wiki users and used content analysis to statistically analyze the interview records,in order to study the significance and value of the Wiki knowledge production model for online users,and to glimpse the impact of the knowledge structure changes in the era of"dataism"on social change.

Research on the High-Quality Development Path of Listed Private Education Groups

The rapid growth of the education industry and private education groups has brought the high-quality development of listed private education companies into focus for both the educational sector and the capital market.This study employs the fuzzy-set qualitative comparative analysis(fsQCA)method to explore pathways to high-quality development for these companies.Necessity analysis confirms that no single factor guarantees a company’s success,highlighting the importance of multi-factor interactions.Three main paths to high-quality development are identified:human resource optimization,precise market positioning,and comprehensive advantage.Conversely,four development paths for non-high-level companies are identified:dual insufficiency in resources and market,high turnover and over-investment,scale expansion with resource mismatch,and inadequate human resource development.The findings indicate that optimal allocation of educational resources,precise market positioning,rational resource allocation,and staff training are crucial for achieving high-quality development.Robustness tests,which raise the consistency threshold,verify the reliability and stability of the results.These findings provide a reference for policymakers,investors,and managers in the education industry.

Exploring the Evolutionary Path of Digital Financial Inclusion in Guangdong Province,China

This study explores the development trajectory of digital financial inclusion in 21 cities in Guangdong Province through fuzzy-set qualitative comparative analysis(fsQCA).The findings emphasize that the success of digital financial inclusion goes beyond individual dimensions,forming a systematic initiative marked by multifaceted interaction among different disciplines.In the trajectory of high-level digital inclusive finance development,the study identifies economic prosperity and technological innovation as crucial elements,highlighting their centrality,and elucidates the synergistic collaboration between market mechanisms and government guidance.Furthermore,the study emphasizes the government’s pivotal role in supporting market mechanisms and guiding policies,highlighting the need to achieve a nuanced equilibrium in the digital financial inclusion strategy.In contrast,non-high-level development paths of digital inclusive finance show a spectrum of diversities,emphasizing the critical roles played by economic fundamentals,government regulation,market mechanisms,and other contextual factors in different trajectories.Regarding policy implications,the study emphasizes the comprehensive and systemic nature inherent in the development of digital inclusive finance.It proposes four policy recommendations,including integrating development strategies,emphasizing scientific and technological innovation and economic development,achieving a delicate balance between market mechanisms and government guidance,and providing precise policy support.These insights provide valuable lessons for shaping digital inclusive financial policies in Guangdong Province and beyond,offering profound insights for strategically constructing robust digital financial ecosystems.

A Causal Configuration Analysis of Payment Decision Drivers in Paid Q&A

Purpose:This paper examines factors of payment decision as well as the role each factor plays in casual configurations leading to high payment intention under systematic and heuristic information processing routes.Design/methodology/approach:Based on heuristic-systematic model(HSM),we propose a configurational analytic framework to investigate complex casual relationships between influencing factors and payment decision.In line with this approach,we use fuzzy-set qualitative comparative analysis(fsQCA)to analyze data crawled from Zhihu.com.Findings:The number of previous consultations is a necessary element in all five equivalent configurations which lead to high intention in payment decision.The heuristic processing route plays a core role while the systematic processing route plays a peripheral role in payment decision-making process.Research limitations:Research is limited in that moderating effect of professional fields has not been considered in the framework.Practical implications:Configurations in results can assist managers of knowledge communities and paid Q&A service providers in the management of information elements to motivate more payment decision.Originality/value:This paper is one of the few studies to apply HSM theory and fsQCA method with respect to the payment decision in paid Q&A.

Intensive Care Nurses’Experiences of Caring for Intubated Patients under Light Sedation:A Qualitative Study

Introduction: Previous studies have shown that a light sedation level is beneficial for intubated patients in the Intensive care unit (ICU). Aim: This study aimed to describe intensive care nurses’ experiences of caring for intubated patients under light sedation. Methods: This study was an explorative descriptive qualitative study. Data were collected from 12 intensive care nurses by three focus group interviews and analyzed using qualitative content analysis. Findings: Five categories emerged from the data: 1) the importance of verbal communication and the nurses’ presence, 2) feelings of frustration and heavy workload, 3) assessment of patients’ pain and anxiety, 4) the nurses’ desire for the development of guidelines, and 5) being inspired by the care. Conclusion: The study found that intensive care nurses were positive towards light sedation care but the organization of care did not support them as the patients cared for with light sedation treatments demanded their physical presence at patients’ bed site.

SYMBOLIC COMPUTATION FOR THE QUALITATIVE THEORY OF DIFFERENTIAL EQUATIONS

This paper provides a survey on symbolic computational approaches for the analysis of qualitative behaviors of systems of ordinary differential equations,focusing on symbolic and algebraic analysis for the local stability and bifurcation of limit cycles in the neighborhoods of equilibria and periodic orbits of the systems,with a highlight on applications to computational biology.

Construction of a General Standard Molecule for the Qualitative Detection in Different Transgenic Foodcrops

Now every laboratory is facing a common problem that is seriously lacking in the standard reference molecule in the GMC detecting research center. Constructing the recombinant plasmid is the urgent demand. In order to overcome this problem, this study respectively cloned CrylA（B）, BAR, CP4-EPSPS, PAT and RBCL genes into PMD 18-T vector. This constructed plasmid could be used as the standard reference molecule in the qualitative detecting of the exogenous CP4-EPSPS gene, CrylA（B） gene, BAR gene and PAT gene. Identification by double restriction endonuclease digestion and identification by PCR proved that the test result was positive. All of these indicated that the established reference molecules in this study were suitable for the qualitative analysis standard of this GMC detection.

The research of mine rock burst hazard identification based on fault tree analysis

In order to identify the rock burst hazard in coalmine and thus to give a credible forecast, firstly, analyzed such effect factors as natural geological factors and mining technological conditions based on the investigation of more than one hundred mine rock burst cases. Secondly, adopted the fault tree analysis （FTA） technology to the mine rock burst hazard identification for the first time and confirmed twelve kinds of basic events, that is, the large mining depth, the burst-orientation coal seams, the solid strata of roof and bottom, near the faults with bigger fall, the folds, the change of seam thickness, other regional tectonics transformation or stress strip, the drilling, blasting and extracting operation, the unscientific extracting methods, the illogical extracting sequence, the residual pillars and the too close distance between the working face and the residual areas or the stopping extracting lines. Moreover, worked out the fault tree of mine rock burst. At last, it made qualitative analysis and quantitative analysis and forecasted the rock burst hazard according to the characteristic of geologic structure and exploitation technology conditions in certain mine of Shandong Province, China, the rock burst accidents happened in the following exploitation validated that it is of feasibility and veracity adopting FTA to identify the mine rock burst hazard.

On Improving Students＇ Listening Proficiency From Correlation Analysis Between English Listening and Other English Skills

Researches have proved that in human beings＇ actual languange communication, listening is the most important part. However, in English learning, listening seems always to be a weakness for many Chinese students. English learning is a systematic process, during which, English listening proficience is influeced by many factors. Therefore, from the systematicness and inner relations in English learning and based on qualitative analysis and quantitative analysis between English listening and other English skills in English listening, this paper tries to give the correlation analysis and accordingly give some suggestions to improve listening proficiency for ESL （English as a second language） learners

The Analysis of the Members＇ Subjective Apiration in Group Psychological Counseling Process

Objective This stud）＇ aims to analyze interpersonal pattern gr-oup psychological counseling process for members＇ subjective apiration. Method Using Nvivo7.0 qualitative analysis software to do the transcripts c-oding analysis of interpersonal pattern group psychological counseling pro-cess. Result Through the qualitative analysis,we fred that members＇ sub-jective apiration have two trends： One trend is with the group psycholo-gical counseling process for increasing;another kind is： increase--decrease--increase ,specificly showing that：：existing subjective apiration-- The subjective will weaken （because of denial and skepticism this group ）or strengthen （accepting this group）-- the subjective apiration increases, applying new pattern in groups--the subjective apiration become specification, the new pattern to repl-ace the old pattern in life. Conclusion 1. In interpersonal group counseling process, members＇ subjective apiration exists two kinds of trend that to weakened after reinforcement and enhancement gradually strengthen： 2. Members＇ subjective apiration of group psychological counseling can influence the effect of group psychological counseling.

The Analysis of the Members＇ Subjective Apiration in Group Psychological Counseling Process

Objective This study aims to analyze interpersonal pattern gr-oup psychological counseling process for members＇ subjective apiration. Method Using Nvivo7.0 qualitative analysis software to do the transcripts c-oding analysis of interpersonal pattern group psychological counseling pro-cess. Result Through the qualitative analysis,we find that members＇ sub-jective apiration have two trends： One trend is with the group psycholo-gical counseling process for increasing;another kind is： increase--decrease--increase, specificly showing that：：existing subjective apiration-- The subjective will weaken （because of denial and skepticism this group ）or strengthen （accepting this group）-- the subjective apiration increases, applying new pattern in groups--the subjective apiration become specification, the new pattern to repl-ace the old pattern in life. Conclusion 1. In interpersonal group counseling process, members＇ subjective apiration exists two kinds of trend that to weakened after reinforcement and enhancement gradually strengthen; 2. Members＇ subjective apiration of group psychological counseling can influence the effect of group psychological counseling.

我国省域公共卫生服务与经济耦合协调及提升路径

目的探究我国各省域公共卫生服务与经济协调发展的现状及其影响因素,为地区实现高效、均衡发展提供建议。方法运用熵权法、耦合协调度、模糊集定性比较分析等方法评价我国各省域公共卫生服务与经济发展协调关系,借助fsQCA 3.0软件探究二者协调关系的影响因素与驱动路径。结果2020年我国各省域公共卫生服务与经济发展耦合协调度属于良好协调等级以上的地区较少,大部分地区处于濒临失调状态。条件变量的必要性检验一致性均≤0.9,单一条件变量对地方公共卫生服务与经济协调发展驱动能力有限,存在多条件变量构成复杂驱动路径。组态分析共得出8种组态结果,共归纳为3种组态路径,其中组态1与组态2属于地方高经济水平主导型驱动路径,组态3、组态4、组态5和组态8属于公共卫生服务与地方经济融合型驱动路径,组态6与组态7属于公共卫生服务主导型驱动路径。结论我国公共卫生服务与经济发展协调性整体不高,每万人口公共卫生机构数、每万人口公共卫生技术人员数以及人均国内生产总值等是影响地方公共卫生服务与经济协调发展的核心因素,不同条件变量组合可促进地方公共卫生服务与经济协调发展。低协调地区可根据本地区实际情况,参考高协调路径,实现公共卫生服务与经济协调发展。

Influence of dissipation on solitary wave solution to generalized Boussinesq equation

This paper uses the theory of planar dynamic systems and the knowledge of reaction-diffusion equations,and then studies the bounded traveling wave solution of the generalized Boussinesq equation affected by dissipation and the influence of dissipation on solitary waves.The dynamic system corresponding to the traveling wave solution of the equation is qualitatively analyzed in detail.The influence of the dissipation coefficient on the solution behavior of the bounded traveling wave is studied,and the critical values that can describe the magnitude of the dissipation effect are,respectively,found for the two cases of b_3<0 and b_3>0 in the equation.The results show that,when the dissipation effect is significant(i.e.,r is greater than the critical value in a certain situation),the traveling wave solution to the generalized Boussinesq equation appears as a kink-shaped solitary wave solution;when the dissipation effect is small(i.e.,r is smaller than the critical value in a certain situation),the traveling wave solution to the equation appears as the oscillation attenuation solution.By using the hypothesis undetermined method,all possible solitary wave solutions to the equation when there is no dissipation effect(i.e.,r=0)and the partial kink-shaped solitary wave solution when the dissipation effect is significant are obtained;in particular,when the dissipation effect is small,an approximate solution of the oscillation attenuation solution can be achieved.This paper is further based on the idea of the homogenization principles.By establishing an integral equation reflecting the relationship between the approximate solution of the oscillation attenuation solution and the exact solution obtained in the paper,and by investigating the asymptotic behavior of the solution at infinity,the error estimate between the approximate solution of the oscillation attenuation solution and the exact solution is obtained,which is an infinitesimal amount that decays exponentially.The influence of the dissipation coefficient on the amplitude,frequency,period,and energy of the bounded traveling wave solution of the equation is also discussed.