Observation on effect of electroacupuncture of different frequencies on patients after thyroid surgery:a randomized controlled trial

Objective To observe postoperative effect of electroacupuncture（EA） of different frequencies in acupuncture anesthesia combined with drugs on patients undergoing thyroid surgery.Methods One hundred and twenty patients undergoing thyroid surgery were randomly divided into a 2Hz electroacupuncture anesthesia group（group A）,a 100 Hz electroacupuncture anesthesia group（group B）,a 2Hz/100 Hz electroacupuncture anesthesia group（group C） and a cervical plexus block group（group D） in accordance with the random number table method,with 30 patients in each group.In group A,group B and group C,electroacupuncture was applied at bilateral Futu（扶突 LI 18）,Hegu（合谷 LI 4） and Neiguan（内关 PC 6） at frequencies of 2 Hz,100 Hz and 2 Hz/100 Hz respectively for 30 min.The needles were retained till the end of the surgery.Dolantin and atropine were intramuscularly injected In group D,bilateral cervical plexus block was produced with a mixture of1%lidocaine and 0.375%bupivicaine.Before surgery,pain threshold and threshold of pain tolerance were determined;during surgery,the duration of surgery was recorded;and after surgery,QOLS（Quality Of Life Score） and PHS（Prince-Henry Score） were assessed.Results PHS in group A,group B and group C were lower than that in group D,respectively（0.20±0.41,0.17±0.38,0.10±0.31 vs 0.40±0.50,P〈0.01）,and PHS in group C was lower than those in group A and group B,respectively（both P〈0.01）.QOLS in group A,group B and group C were higher than that in group D,respectively（9.97±1.07,9.97±2.27,10.40±1.45 vs 9.73±1.41,P〈0.05,P〈0.01）,and QOLS in group C was higher than those in group A and group B,respectively（both P〈0.05）.Conclusion Acupuncture anesthesia combined with drugs has better postoperative effect than drug anesthesia.Electroacupuncture of different frequencies can significantly improve general quality of life of patients,so patients recover well after thyroid surgery.As patients in group C suffered from the slightest pain with the highest quality of life,they recovered best within the shortest time.Electroacupuncture at frequency of 2 Hz/100 Hz can better play postoperative analgesic effect.

Regulation of Acupuncture on Interferon-γand Tumor Necrosis Factor of Lung Cancer-Operative Cases

Objective： To investigate tumor necrosis factor （TNF） of lung the regulation of acupuncture on γ-interteron （LNF-γ） and cancer-operative cases. Methods： to determine the INF-γ and TNF contents in the blood serum of lung cancer patients by double antibody sandwich immunoenzymatic method （ELISA）; to measure the INF-γ and TNF contents of 30 lung cancer patients in the acupuncture anesthesia group and 30 lung cancer patients in general anesthesia group before the operation and at the 8th days, the 12th day after the operation respectively and make comparison between the two groups. Results. The pre-operation INF-γ contents of the two groups showed no significant difference （P〉 0.05）; the post operation INF-γ contents of the two groups showed significant difference at 8th day and 12th day after the operation （P〈 0.05）; the acupuncture anesthesia group was superior to the general anesthesia group; the self-comparison of the anesthesia group showed significant difference at the 12th day and 8th day after the operation （P〈 0.05）; the pre-operation TNF contents of the two groups showed no significant difference （P〉 0.05） and the post-operation TNF contents of the two groups showed significant difference at the 8th day and 12th day after the operation （P〈 0.05）. Conclusion：Acupuncture can increase the serum INF-γ and TNF contents of lung cancer patients and therefore regulate the immunity of the patients.