Objective To investigate whether lung inflation during cardiopulmonary by -pass (CPB) surgeryfor congenital heart disease is needed to maintain adequate lung mechanics and surfactant phospholipidproduction. Methods Th...Objective To investigate whether lung inflation during cardiopulmonary by -pass (CPB) surgeryfor congenital heart disease is needed to maintain adequate lung mechanics and surfactant phospholipidproduction. Methods Thirty patients (2～10 year) with atrial or ventricular septal defects were randomly dividedinto 3 groups. group I (control group). IPPV; group Ⅱ： PEEP= 0.392kpa; group Ⅲ: IPPV and lungs inflated with0.392kPa during CPB. Results Crs was measured and airway aspirates were obtained. At the end of surgery,compared with the other 2 groups Crs, SatPC/TP and SatPC/TPL was decreased significantly in group I andlower than its baseline (P<0.05). Conclusio Use of PEEP and lung inflation during open heart surgery inchildren was more effective to improve lung function and surfactant phospholipid production.展开更多
文摘Objective To investigate whether lung inflation during cardiopulmonary by -pass (CPB) surgeryfor congenital heart disease is needed to maintain adequate lung mechanics and surfactant phospholipidproduction. Methods Thirty patients (2～10 year) with atrial or ventricular septal defects were randomly dividedinto 3 groups. group I (control group). IPPV; group Ⅱ： PEEP= 0.392kpa; group Ⅲ: IPPV and lungs inflated with0.392kPa during CPB. Results Crs was measured and airway aspirates were obtained. At the end of surgery,compared with the other 2 groups Crs, SatPC/TP and SatPC/TPL was decreased significantly in group I andlower than its baseline (P<0.05). Conclusio Use of PEEP and lung inflation during open heart surgery inchildren was more effective to improve lung function and surfactant phospholipid production.
