AIM: To determine the frequency, subtype,complications, treatment and visual prognosis of uveitis in patients with multiple sclerosis(MS). METHODS: A total of 1702 MS patients’ medical records were reviewed for a his...AIM: To determine the frequency, subtype,complications, treatment and visual prognosis of uveitis in patients with multiple sclerosis(MS). METHODS: A total of 1702 MS patients’ medical records were reviewed for a history of uveitis both with a neurologist and an ophthalmologist.RESULTS: Nine patients(0.52%) with uveitis were detected. Eight of them were female, one was male. The mean age was 42.0±14.1y(range 22-66). Seven patients were relapsing remitting MS, two were secondary progressive MS. The mean duration of MS was 10.8 ±10.3y, and the mean duration of uveitis 10.3 ±9.9y. The onset of uveitis preceded that of MS(four patients) by a mean of 5.0±4.3y(range 1-11). MS diagnosed prior to the onset of uveitis(five patients) by an interval of 0.75-16y(mean 4.95 ±6.24y). There were 16 affected eyes of nine patients. The most common types of uveitis were panuveitis and intermediate uveitis. Uveitis was bilateral in most patients. The most common complications were cataract and glaucoma, and patients with such complications were surgically treated. The range of visual acuity of affected eyes was 20/800 to 20/22, with only six of 16 affected eyes better than 20/40. After treatment, the visual acuity of the affected eyes was better than 20/40 in11 of 16 eyes. CONCLUSION: Uveitis should be considered when assessing an MS patient with visual loss, as surgical interventions other than medical treatments may be needed to improve visual function. Complications could be seen more often when posterior segment is involved.展开更多
AIM:To describe the clinical characteristics and surgical outcomes of complicated cataract with pediatric trematodal granulomatous uveitis(TGU).METHODS:Patients of cataract with TGU in the membranous(inactive) stage u...AIM:To describe the clinical characteristics and surgical outcomes of complicated cataract with pediatric trematodal granulomatous uveitis(TGU).METHODS:Patients of cataract with TGU in the membranous(inactive) stage underwent cataract surgery with intraocular lens(IOL) implantation.Preoperative history and ophthalmic examination were conducted for all cases,whereas Schimphlug imaging and corneal topography were done for some patients.Postoperative follow up was done on the 1st,2nd,and 5th postoperative days after surgery.Then,it was done at least at one,three,and six months postoperatively.Intraoperative and postoperative complications and the methods of their management were reported.RESULTS:Twelve eyes of 12 male children were included in this study ranging from 8 to 16y.The mean best corrected Snellen visual acuity(BCVA) was significantly improved from 0.09±0.06 preoperatively to 0.37±0.11 at the final visit 6mo postoperatively(P<0.001).Schimphlug imaging and corneal topography showed flattening of the anterior surface of the inferior cornea.Intraoperative difficulties and complications included the poor dilatability of the drown down pupil,strong posterior synechia between the anterior lens capsule and the iris at the site of the inferior retrocorneal vascularized membrane and hyphema.All cases underwent primary hydrophobic IOL implantation.CONCLUSION:Surgery for this type of cataract is relatively safe and effective.It is associated with some specific difficulties and complications that should be considered during surgery and follow up.展开更多
Purpose:To report a case of presumed acquired retinal astrocytoma in association with anterior uveitis. Methods:A 29-year-old man presented with mutton fat keratic precipitates in the inferiorlower cornea,with complic...Purpose:To report a case of presumed acquired retinal astrocytoma in association with anterior uveitis. Methods:A 29-year-old man presented with mutton fat keratic precipitates in the inferiorlower cornea,with complicated cataract and a circumscribed,solitary,yellowish-white retinal lesion in the right eye.Phacoemulsification with intraocular lens implantation was performed, with election to observeand the lesion was observed periodically. The lesion was followed for over two years without any change in size, shape or, and appearance. The anterior uveitis has not recurred at the time of writing. Results:Systemic medical and laboratory evaluations, including chest computed tomography,cranial magnetic resonance imaging,and serum angiotensin converting enzyme level, were normal. The characteristic fundus, FA,OCT scan, ultrasound scan,and lack of other contributory laboratory findings strongly supported the diagnosis of acquired retinal astrocytoma in this patient. Conclusion:We hypothesized that anterior uveitis may contribute to the growth and maintenance of retinal lesions. (Eye Science 2013; 28:51-54)展开更多
文摘AIM: To determine the frequency, subtype,complications, treatment and visual prognosis of uveitis in patients with multiple sclerosis(MS). METHODS: A total of 1702 MS patients’ medical records were reviewed for a history of uveitis both with a neurologist and an ophthalmologist.RESULTS: Nine patients(0.52%) with uveitis were detected. Eight of them were female, one was male. The mean age was 42.0±14.1y(range 22-66). Seven patients were relapsing remitting MS, two were secondary progressive MS. The mean duration of MS was 10.8 ±10.3y, and the mean duration of uveitis 10.3 ±9.9y. The onset of uveitis preceded that of MS(four patients) by a mean of 5.0±4.3y(range 1-11). MS diagnosed prior to the onset of uveitis(five patients) by an interval of 0.75-16y(mean 4.95 ±6.24y). There were 16 affected eyes of nine patients. The most common types of uveitis were panuveitis and intermediate uveitis. Uveitis was bilateral in most patients. The most common complications were cataract and glaucoma, and patients with such complications were surgically treated. The range of visual acuity of affected eyes was 20/800 to 20/22, with only six of 16 affected eyes better than 20/40. After treatment, the visual acuity of the affected eyes was better than 20/40 in11 of 16 eyes. CONCLUSION: Uveitis should be considered when assessing an MS patient with visual loss, as surgical interventions other than medical treatments may be needed to improve visual function. Complications could be seen more often when posterior segment is involved.
文摘AIM:To describe the clinical characteristics and surgical outcomes of complicated cataract with pediatric trematodal granulomatous uveitis(TGU).METHODS:Patients of cataract with TGU in the membranous(inactive) stage underwent cataract surgery with intraocular lens(IOL) implantation.Preoperative history and ophthalmic examination were conducted for all cases,whereas Schimphlug imaging and corneal topography were done for some patients.Postoperative follow up was done on the 1st,2nd,and 5th postoperative days after surgery.Then,it was done at least at one,three,and six months postoperatively.Intraoperative and postoperative complications and the methods of their management were reported.RESULTS:Twelve eyes of 12 male children were included in this study ranging from 8 to 16y.The mean best corrected Snellen visual acuity(BCVA) was significantly improved from 0.09±0.06 preoperatively to 0.37±0.11 at the final visit 6mo postoperatively(P<0.001).Schimphlug imaging and corneal topography showed flattening of the anterior surface of the inferior cornea.Intraoperative difficulties and complications included the poor dilatability of the drown down pupil,strong posterior synechia between the anterior lens capsule and the iris at the site of the inferior retrocorneal vascularized membrane and hyphema.All cases underwent primary hydrophobic IOL implantation.CONCLUSION:Surgery for this type of cataract is relatively safe and effective.It is associated with some specific difficulties and complications that should be considered during surgery and follow up.
文摘Purpose:To report a case of presumed acquired retinal astrocytoma in association with anterior uveitis. Methods:A 29-year-old man presented with mutton fat keratic precipitates in the inferiorlower cornea,with complicated cataract and a circumscribed,solitary,yellowish-white retinal lesion in the right eye.Phacoemulsification with intraocular lens implantation was performed, with election to observeand the lesion was observed periodically. The lesion was followed for over two years without any change in size, shape or, and appearance. The anterior uveitis has not recurred at the time of writing. Results:Systemic medical and laboratory evaluations, including chest computed tomography,cranial magnetic resonance imaging,and serum angiotensin converting enzyme level, were normal. The characteristic fundus, FA,OCT scan, ultrasound scan,and lack of other contributory laboratory findings strongly supported the diagnosis of acquired retinal astrocytoma in this patient. Conclusion:We hypothesized that anterior uveitis may contribute to the growth and maintenance of retinal lesions. (Eye Science 2013; 28:51-54)
