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Outcomes of cervical degenerative disc disease treated by anterior cervical discectomy and fusion with self-locking fusion cage 被引量:2
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作者 Bo Zhang Yu-Zhen Jiang +1 位作者 Qing-Peng Song Yan An 《World Journal of Clinical Cases》 SCIE 2022年第15期4776-4784,共9页
BACKGROUND Cervical degenerative disc(CDD)disease is a common type of spondylosis.Although anterior cervical discectomy and fusion(ACDF)is the preferred treatment for CDD disease,internal fixation with a titanium plat... BACKGROUND Cervical degenerative disc(CDD)disease is a common type of spondylosis.Although anterior cervical discectomy and fusion(ACDF)is the preferred treatment for CDD disease,internal fixation with a titanium plate may cause various complications.The invention of the ACDF with a self-locking fusion cage(ROI-C)has effectively decreased the incidence of postoperative complications.AIM To observe the outcomes of CDD disease treated by ACDF with a ROI-C.METHODS Ninety patients with CDD disease treated at our hospital from March 2019 to March 2021 were included.They were divided into two groups(control group and observation group,n=45 in each)using a random number table.Patients in the control group received ACDF plus internal fixation with a titanium plate.Those in the observation group received ACDF+ROI-C placement.The two groups of patients were compared in terms of surgical parameters,pain,cervical spine function,range of motion,and complications.RESULTS The two groups of patients showed no significant differences in surgical time,blood loss,drainage volume,and length of hospital stay(P>0.05).No significant differences in the visual analogue scale(VAS),Japanese Orthopedic Association(JOA),and neck disability index(NDI)scores were observed between the two groups before surgery(P>0.05).The VAS and NDI scores in the observation group were considerably lower than those in the control group after surgery;however,the JOA scores in the observation group were significantly higher than those in the control group(P<0.05).No significant differences were observed in cervical disc height and the range of motion of the superior or inferior adjacent vertebrae between the two groups before surgery(P>0.05).The disc height in the observation group was larger than that in the control group after surgery.The range of motion of both the superior and inferior adjacent vertebrae was significantly smaller in the observation group than in the control group(P<0.05).The incidence of complications was only 2.22% in the observation group compared to 15.56% in the control group,and the difference was statistically significant(P<0.05).CONCLUSION Cervical spine function restoration was better with ROI-C with internal fixation in ACDF than with conventional titanium plates in ACDF for CDD disease. 展开更多
关键词 Degenerative disc disease Self-locking fusion cage featuring VerteBRIDGE plates anterior cervical discectomy and fusion Therapy
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Anterior Discectomy and Fusion versus Posterior Foraminotomy in Treatment of Cervical Radiculopathy: A Comparative Prospective Study 被引量:2
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作者 Ahmad Abdalla Ali A. Abd Elaleem 《Open Journal of Modern Neurosurgery》 2019年第4期441-451,共11页
Introduction: Cervical radiculopathy is caused by either cervical disc herniation or bone spurs due to cervical spine degeneration. It is common in middle aged and elderly patients. Those patients who are refractory t... Introduction: Cervical radiculopathy is caused by either cervical disc herniation or bone spurs due to cervical spine degeneration. It is common in middle aged and elderly patients. Those patients who are refractory to conservative treatment are candidates for surgical management. The surgical approaches for cervical radiculopathy are either anterior cervical discectomy and fusion (ACDF) or posterior cervical foraminotomy (PCF). In spite of many reports on ACDF and PCF, only a few studies directly compare the outcomes of both techniques. Purpose: To compare anterior cervical discectomy and fusion (ACDF) with posterior cervical foraminotomy (PCF) for the treatment of cervical radiculopathy, regarding the surgical, clinical and radiological outcomes. Patient and methods: This is a prospective randomized controlled clinical study carried on 44 patients with unilateral cervical radiculopathy. They are divided into 2 groups;group (A) included 23 patients who underwent ACDF and group (B) included 21 patients who underwent PCF, with 1 year follow up. The patient age, sex, clinical manifestations, surgical outcomes as number of cervical level, operative time, blood loss, complications and length of hospital stay were recorded. Visual analogus scale (VAS) and neck disability index (NDI) were used for evaluation of clinical outcomes. Postoperative imaging was done after 1 year to detect instability or adjacent level degeneration. Chi-square and unpaired T-test were used to compare the mean values of both groups. Results: The mean age was nearly 45 years for both groups. C5-6 ACDF was the most common level in group (A), while C6-7 PCF was the most frequent operated level in group (B). PCF group had less operative time, blood loss and length of hospital stay than ACDF group. Clinical improvement of the mean values of VAS and NDI were more pronounced in PCF group as compared to ACDF group with statistically significant difference. No cases of cervical instability were recorded during the period of follow up. Conclusion: Posterior cervical foraminotomy is a safe and effective technique for the treatment of cervical radiculopathy as compared to anterior cervical discectomy and fusion. PCF has a shorter operative time, less hospital stay and better clinical outcome. 展开更多
关键词 cervical Radiculopathy anterior cervical discectomy and fusion POSTERIOR cervical FORAMINOTOMY
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Delayed massive cerebral infarction after perioperative period of anterior cervical discectomy and fusion:A case report
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作者 Fei Jia Chuan-Chao Du Xiao-Guang Liu 《World Journal of Clinical Cases》 SCIE 2021年第28期8602-8608,共7页
BACKGROUND Cerebral infarction is an extremely rare postoperative complication of anterior cervical discectomy and fusion(ACDF),particularly in the delayed setting.We present a case who had a sudden stroke on day 18 a... BACKGROUND Cerebral infarction is an extremely rare postoperative complication of anterior cervical discectomy and fusion(ACDF),particularly in the delayed setting.We present a case who had a sudden stroke on day 18 after surgery.By sharing our experience with this case,we hope to provide new information about stroke after anterior cervical surgery.CASE SUMMARY We present the case of a 61-year-old man with more than 20 years of hypertension and 14 years of coronary heart disease who had suffered a stroke 11 years ago.The patient was admitted for a multiple ACDF due to symptoms of cervical spondylotic myelopathy and had a sudden stroke on day 18 after surgery.Imaging findings showed a large-area infarct of his left cerebral hemisphere and thrombosis in his left common carotid artery.With the consent of his family,the thrombus was removed and a vascular stent was implanted through an interventional operation.Forty days later,the patient was transferred to a rehabilitation hospital for further treatment.He had normal consciousness but slurred speech at the 1-year follow-up evaluation.The motor and sensory functions of his hemiplegic limbs partially recovered.CONCLUSION This case illustrated that a postoperative stroke related to anterior cervical surgery may be attributed to prolonged carotid retraction and might have a long silent period.Preventive measures include careful preoperative and postoperative examination for high-risk patients as well as gentle and intermittent retraction of carotid artery sheath during operation. 展开更多
关键词 anterior cervical discectomy and fusion Cerebral infarction Carotid artery Postoperative complication Case report
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Mid-term outcomes of Bryan cervical disc arthroplasty versus anterior cervical discectomy and fusion for cervical spondylopathy
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作者 郝定均 《外科研究与新技术》 2011年第2期84-84,共1页
Objective To compare the clinical outcomes of Bryan disc replacement with anterior cervical discectomy and fusion (ACDF) in patients with cervical spondylopathy. Methods Sixteen patients underwent Bryan cervicaldisc r... Objective To compare the clinical outcomes of Bryan disc replacement with anterior cervical discectomy and fusion (ACDF) in patients with cervical spondylopathy. Methods Sixteen patients underwent Bryan cervicaldisc replacement (A group) ,and 展开更多
关键词 Mid-term outcomes of Bryan cervical disc arthroplasty versus anterior cervical discectomy and fusion for cervical spondylopathy
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Multilevel cervical spondylotic myelopathy treated by anterior cervical decompression in subsection and autograft fusion 被引量:4
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作者 赵建华 刘鹏 李起鸿 《Journal of Medical Colleges of PLA(China)》 CAS 2007年第4期209-215,共7页
Objective:To investigate a novel surgical method for multilevel cervical spondylotic myelopathy (CSM). Methods: Totally 21 patients with multilevel CSM undergoing a novel surgical procedure from April 2001 to Janu... Objective:To investigate a novel surgical method for multilevel cervical spondylotic myelopathy (CSM). Methods: Totally 21 patients with multilevel CSM undergoing a novel surgical procedure from April 2001 to January 2004 were analyzed retrospectively. All patients experienced anterior cervical decompression surgery in subsection, autograft fusion and internal fixation. Preoperative, immediate postoperative and follow-up image data, X-rays and semi-quantitative Japanese orthopaedics association (JOA) scores were used to evaluate the restoration of lordosis (Cobb's angle), intervertebral heights, the stability of the cervical spine and the improvement of neurological impairment. Results: Preoperative symptoms were markedly alleviated or disappeared in most of the patients. According to the JOA scores, the ratio of improvement in neurological function was 72. 2%, including excellent in 9 cases (42.9%), good in 7 cases (33.3%), fair in 3 cases (14.3%) and poor in 2 cases (9.5%). Immediate postoperative X-rays showed obvious improvements in lordosis and in the intervertebral height of the cervical spine (P〈0. 01). There is no evidence of instrument failure during the mean follow-up period of 14. 2 months (9-24 months, P〉0. 01). Conclusion:Anterior cervical decompression in subsection, autograft fusion and internal fixation is a rational effective method for the surgical treatment of multilevel CSM. 展开更多
关键词 cervical spondylotic myelopathy MULTILEVEL anterior decompression fusion internal fixation
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Multilevel Anterior Cervical Decompression and Fusion: Cervical Range of Motion and Clinical Outcomes
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作者 Ahmed Hosameldin Abdelrahman Senosi Mostafa Abdel-Latif 《Open Journal of Modern Neurosurgery》 2022年第4期181-196,共16页
Background: Multiple level anterior cervical discectomy and fusion (ACDF) is indicated for those who suffer from multilevel stenosis or compression of the spinal canal. It was reported that this intervention would unf... Background: Multiple level anterior cervical discectomy and fusion (ACDF) is indicated for those who suffer from multilevel stenosis or compression of the spinal canal. It was reported that this intervention would unfortunately lead to a loss of normal cervical range of motion (CROM). Although, fewer studies have demonstrated the exact impact of the procedure on CROM. In our study, short and midterm postoperative CROM was described. Methods: Ninety patients who underwent ACDF were followed up postoperatively for at least 3 months. Active CROM was measured in all patients preoperatively and in postoperative follow-ups by cervical spine X-rays in lateral dynamic view using Cobb’s angle method. Results: Unfortunately, postoperative CROM was significantly diminished. At the short-term (3 months) follow-up there was a great limitation in CROM. While an obvious increase in CROM at the midterm (6 months) follow-up was observed in flexion especially. The reduction in global ROM (calculated as preoperative global ROM – 6 months postoperative ROM) was 4.1 and the reduction rate (calculated as reduction ROM divided by preoperative ROM) was 9.5%. The recovery ROM (calculated as 6 months postoperative ROM – 1 month postoperative ROM) was 8.2. The recovery rate (calculated as recovery ROM divided by 1 month postoperative ROM) was 26.5%. Conclusion: Active CROM following multiple level ACDF was obviously diminished. The most affected motion after surgery was flexion. It was noticed that at the short-term follow-up CROM would be more limited while after further follow up CROM was obviously improved even in neck flexion motion. 展开更多
关键词 MULTILEVEL anterior cervical discectomy fusion cervical Range of Motion
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一种新开发的牵开系统在显微镜辅助经前路颈椎间盘切除与融合术治疗颈椎病中的应用
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作者 钱湖 韦贵火 +1 位作者 敖俊 覃建朴 《遵义医科大学学报》 2025年第1期53-58,共6页
目的旨在介绍一种新开发的牵开系统,并分析其在显微镜辅助经前路颈椎间盘切除与融合术(ACDF)治疗颈椎病的可行性和安全性。方法回顾性收集并分析2019年1月至2023年11月于遵义医科大学附属医院诊断为颈椎病,且使用新开发的牵开系统进行... 目的旨在介绍一种新开发的牵开系统,并分析其在显微镜辅助经前路颈椎间盘切除与融合术(ACDF)治疗颈椎病的可行性和安全性。方法回顾性收集并分析2019年1月至2023年11月于遵义医科大学附属医院诊断为颈椎病,且使用新开发的牵开系统进行显微镜辅助下ACDF的患者资料,评估该牵开系统的可行性及安全性。结果本研究共纳入48例患者。术后影像学数据显示,减压充分,手术效果良好。视觉模拟评分(VAS)和颈部残疾指数评分(NDI)分别从术前的(5.43±1.12、29.77±6.06)分下降至术后的(2.60±0.78、11.75±3.26)分。日本骨科协会评分(JOA)从术前的(7.93±1.37)分上升至术后的(12.22±1.71)分。C2-7的Cobb角从术前的(10.37±6.79)度增加到手术后(14.58±6.10)度。未观察到临床或影像学相关并发症。结论新开发的牵开系统在显微镜辅助下ACDF手术中表现出良好的可行性和安全性,可为临床应用提供一种新的选择。 展开更多
关键词 颈椎病 牵开器 前路颈椎间盘切除与融合术 显微镜
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Dysphagia in a patient with ankylosing spondylitis:A case report
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作者 Xin-Wen Wang Wen-Zhi Zhang 《World Journal of Clinical Cases》 SCIE 2021年第7期1639-1645,共7页
BACKGROUND Ankylosing spondylitis(AS)is a systematic and rheumatic disease,which causes multiple symptoms.However,dysphagia due to the formation of a giant anterior cervical osteophyte is rare in patients with AS.CASE... BACKGROUND Ankylosing spondylitis(AS)is a systematic and rheumatic disease,which causes multiple symptoms.However,dysphagia due to the formation of a giant anterior cervical osteophyte is rare in patients with AS.CASE SUMMARY We present the case of a 65-year-old male patient who was diagnosed with AS and visited the hospital with a complaint of progressive dysphagia.The appropriate imaging examinations indicated that a giant anterior cervical osteophyte at C3-4 caused esophageal compression,which led to dysphagia.An operation for resection was performed without complications.CONCLUSION This case demonstrates that a large cervical osteophyte may be the cause of dysphagia in patients with AS,and early accurate diagnosis and surgical treatment are very important for the improvement of symptoms.Anterior cervical discectomy and fusion are extremely effective and should be taken into consideration. 展开更多
关键词 Ankylosing spondylitis DYSPHAGIA Giant osteophyte cervical spine anterior cervical discectomy and fusion Case report
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Cervicogenic exophthalmos: Possible etiology and pathogenesis
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作者 Chi-Ming Wu Hung-En Liao +1 位作者 Shang-Wei Hsu Shou-Jen Lan 《World Journal of Clinical Cases》 SCIE 2020年第2期318-324,共7页
BACKGROUND Unilateral exophthalmos is often caused by inflammation, neoplasm, infection,metabolic disease, vascular disorder and several other less common conditions.Reflex sympathetic dystrophy related to unilateral ... BACKGROUND Unilateral exophthalmos is often caused by inflammation, neoplasm, infection,metabolic disease, vascular disorder and several other less common conditions.Reflex sympathetic dystrophy related to unilateral exophthalmos has not been reported in the past literature.CASE SUMMARY We describe a 45-year-old female with unilateral exophthalmos caused by reflex sympathetic dystrophy and its unexpected spontaneous disappearance after a standard anterior cervical discectomy and fixation operation with two PEEK interbody cages and a plate. To our surprise, the patient’s left unilateral exophthalmos improved spontaneously in the morning on postoperative day 2-with no relapse, without any further medication, as of seven years. We have named this condition "cervicogenic exophthalmos."CONCLUSION We would inform other clinicians that unilateral exophthalmos was caused not only by inflammation, vascular disorder, infection, neoplasm, or metabolic disease, but also by reflex sympathetic dystrophy related with cervicogenic spondylosis. To the best of our knowledge, ours is the first related case report and use of the term "cervicogenic exophthalmos" after reviewing previous literature. 展开更多
关键词 EXOPHTHALMOS Reflex sympathetic dystrophy anterior cervical discectomy and fixation PEEK cage Cervicogenic exophthalmos Cervicogenic spondylosis Case report
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加速康复外科模式下的加速康复护理干预在前路颈椎间盘切除融合术患者中的应用效果分析
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作者 钱瑜 刘欢 +4 位作者 赵中晶 肖玮 吴浩 王凯 冯帅 《中国医刊》 CAS 2024年第8期852-855,共4页
目的探讨加速康复外科(ERAS)模式下的加速康复护理干预在前路颈椎间盘切除融合术(ACDF)患者中的应用效果。方法选取2020年5月至2021年5月首都医科大学宣武医院收治的162例接受ACDF治疗的颈椎病患者为研究对象,在组间基线特征可比的原则... 目的探讨加速康复外科(ERAS)模式下的加速康复护理干预在前路颈椎间盘切除融合术(ACDF)患者中的应用效果。方法选取2020年5月至2021年5月首都医科大学宣武医院收治的162例接受ACDF治疗的颈椎病患者为研究对象,在组间基线特征可比的原则上,采用随机数字表法分为对照组和观察组,每组81例。对照组患者给予常规护理干预,观察组患者给予ERAS模式下的加速康复护理干预。比较分析两组患者的术后胃肠功能、术后疼痛程度、导尿管拔除时间、首次下床时间及住院时间。结果两组患者的术后恶心、呕吐发生率比较差异无统计学意义(P>0.05);观察组患者的首次排气时间、首次排便时间、首次进食固体食物时间、导尿管拔除时间、首次下床时间、住院时间、静息时的视觉模拟评分法评分、运动时的视觉模拟评分法评分均短于或低于对照组,差异均有统计学意义(P<0.05)。结论实施ERAS模式下的加速康复护理干预可显著改善接受ACDF治疗的颈椎病患者的术后胃肠功能,促进患者的术后恢复进程,值得临床应用。 展开更多
关键词 加速康复外科 颈椎病 前路颈椎间盘切除融合术
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颈椎前路椎间盘切除融合术后患者运动恐惧分型及影响因素
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作者 申荣华 李秀莉 +1 位作者 王健 杨洁 《河北医药》 CAS 2024年第20期3173-3177,共5页
目的分析颈椎前路椎间盘切除融合(anterior cervical discectomy and fusion,ACDF)术后患者运动恐惧分型及影响因素,为制订针对性干预方案提供参考。方法采用横断面调查,选取2022年1月至2023年6月收治的ACDF术后患者作为调查对象,采用... 目的分析颈椎前路椎间盘切除融合(anterior cervical discectomy and fusion,ACDF)术后患者运动恐惧分型及影响因素,为制订针对性干预方案提供参考。方法采用横断面调查,选取2022年1月至2023年6月收治的ACDF术后患者作为调查对象,采用一般资料调查表、恐动症Tampa评分量表、多维度运动自我效能量表进行调查。使用潜在剖面分析识别患者运动恐惧分型,二元Logistic回归分析不同运动恐惧类别的影响因素。结果最终纳入137例ACDF术后患者,其运动恐惧分为2个潜在剖面类别:“高恐惧—运动恐惧型”54例占39.4%,“低恐惧—运动回避型”83例占60.6%。相比较于“低恐惧—运动回避型”,女性、体重指数>24.0 kg/m^(2)、运动自我效能得分低的患者发展为“高恐惧—运动恐惧型”的概率大(OR=0.476、0.700、-1.305,P<0.05)。结论ACDF术后患者运动恐惧有2种潜在剖面类别,医护人员应根据其运动恐惧分型,实施针对性干预,以提高其康复运动的积极性。 展开更多
关键词 颈椎病 前路椎间盘切除融合术 运动恐惧 潜在剖面分析 影响因素分析
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显微镜辅助椎间盘切除融合内固定术对局限型后纵韧带骨化症的疗效研究
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作者 常跃文 朱文俊 +1 位作者 顾伟 冯俊涛 《实用临床医药杂志》 CAS 2024年第21期17-21,共5页
目的探析局限型后纵韧带骨化症(OPLL)患者接受显微镜下椎间盘切除融合内固定术(ACDF)治疗的近期与远期疗效情况。方法回顾性选取2020年2月—2022年2月收治的局限型OPLL患者105例,按照ACDF治疗过程中是否辅助使用显微镜分为显微镜组56例... 目的探析局限型后纵韧带骨化症(OPLL)患者接受显微镜下椎间盘切除融合内固定术(ACDF)治疗的近期与远期疗效情况。方法回顾性选取2020年2月—2022年2月收治的局限型OPLL患者105例,按照ACDF治疗过程中是否辅助使用显微镜分为显微镜组56例和常规组49例,观察围术期指标、视觉模拟评分法(VAS)评分、健康调查评估量表(SF-36)评分、椎管最狭窄处椎管面积与脊髓前后径、颈椎活动度、椎间隙高度、关节功能[日本骨科医师协会评分(JOA)颈椎病评分及颈部障碍指数(NDI)]及并发症风险。结果显微镜组平均手术时间(141.85±18.35)min、平均住院时间(10.18±1.58)d短于常规组的(159.46±21.42)min、(12.03±1.82)d,显微镜组术中平均出血量(80.65±7.28)mL少于常规组的(103.52±10.43)mL,差异有统计学意义(P<0.05);显微镜组术后6个月VAS评分(2.82±0.53)分、SF-36评分(79.56±5.68)分优于常规组的(3.51±0.60)、(72.35±4.77)分,差异有统计学意义(P<0.05);显微镜组与常规组在术后椎管面积、脊髓前后径上比较[(138.24±24.32)mm^(2)与(123.62±18.74)mm^(2),(5.42±0.46)mm与(4.73±0.51)mm],差异有统计学意义(P<0.05);显微镜组与常规组在术后6个月颈椎活动度上比较[(25.21±3.37)°与(28.65±3.56)°],差异有统计学意义(P<0.05);显微镜组并发症发生率为5.36%,低于常规组的18.37%,差异有统计学意义(P<0.05);显微镜组与常规组JOA、NDI评分在时间、组间和交互效应上比较,差异有统计学意义(P<0.05)。结论局限型OPLL患者实施ACDF治疗过程中借助显微镜提供清晰视野,并对骨化灶采用磨钻磨除、打薄处理,能更有效地解除脊髓压迫,改善近期疼痛和关节功能状况,降低脊髓损伤等并发症风险。 展开更多
关键词 后纵韧带骨化症 椎间盘切除融合内固定术 显微镜 椎管面积 脊髓前后径 关节功能
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不同融合装置对脊髓型颈椎病前路椎管减压融合后颈椎矢状位参数的影响 被引量:1
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作者 任杭岭 宋娜 +3 位作者 徐大霞 李宗欢 张志 张景涛 《中国组织工程研究》 CAS 北大核心 2024年第33期5375-5381,共7页
背景:颈前路手术对颈椎矢状位平衡参数的影响逐渐被关注,目前对于双节段颈椎病的术式选择缺乏明确可行的临床指南,寻求最适合的固定方式更有益于此类型患者。目的:对比颈前路减压不同融合装置对邻近双节段脊髓型颈椎病术后颈椎矢状位参... 背景:颈前路手术对颈椎矢状位平衡参数的影响逐渐被关注,目前对于双节段颈椎病的术式选择缺乏明确可行的临床指南,寻求最适合的固定方式更有益于此类型患者。目的:对比颈前路减压不同融合装置对邻近双节段脊髓型颈椎病术后颈椎矢状位参数变化的影响。方法:回顾性分析2018年3月至2020年9月聊城市人民医院收治的符合选择标准的邻近双节段脊髓型颈椎病患者44例,全部患者均行前路椎间盘切除椎管减压融合治疗,根据椎间融合装置的不同分为2组,零切迹组(zero-p组)纳入患者23例,钛板联合cage组(cage组)纳入患者21例。所有患者术前完善颈椎正侧位X射线片、颈椎CT及MRI检查,末次随访时拍摄颈椎正侧位X射线片,手术前后于X射线片上测量颈椎矢状位平衡参数,包括颈椎前凸角(C2-7 Cobb角)、颈椎矢状位垂直距离、病椎局部前凸角和T1倾斜角。记录手术时间、术中出血量、末次随访椎间融合以及术后吞咽障碍发生情况,并于术前及术后评估患者日本骨科学会颈椎评分。计算两组患者手术前后颈椎矢状位参数变化值并对比其差异。结果与结论:①两组患者均顺利完成手术并获得随访,zero-p组手术时间较cage组短,术中出血量较cage组少,但差异无显著性意义(P>0.05);②cage组术后吞咽障碍发生率(7/21,33%)高于zero-p组(3/23,13%),差异有显著性意义(P<0.05);③末次随访时,两组临床疗效相同,均骨性融合;组内比较发现两组颈椎矢状位参数指标均较术前改善(P<0.05);组间比较末次随访时各矢状位参数差异均无显著性意义(P>0.05);两组间颈椎矢状位垂直距离、C2-7 Cobb角、T1倾斜角变化值比较差异均无显著性意义(P>0.05),但zero-p组病椎局部前凸角变化值较cage组小,差异有显著性意义(P<0.05);④提示前路椎间盘切除椎管减压融合过程中使用zero-p与钛板联合cage均能有效改善颈椎矢状面平衡,钛板联合cage椎间融合可以更好地重建患者颈椎前凸曲度,对于融合装置的选择还应综合考虑手术并发症的发生情况。 展开更多
关键词 脊髓型颈椎病 前路椎间盘切除减压融合 椎间融合 zero-p 钛板 颈椎矢状位参数
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颈前路椎间盘切除减压融合术联合术后中药治疗神经根型颈椎病的临床研究 被引量:2
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作者 杨姝玥 樊思远 +2 位作者 庄子逸 移平 唐向盛 《中日友好医院学报》 CAS 2024年第2期82-86,共5页
目的:探究中药联合颈前路椎间盘切除减压融合术治疗神经根型颈椎病的临床疗效,术后使用中药是否能够促进患者康复。方法:回顾性分析2019年10月—2022年2月在中日友好医院脊柱外科行颈前路椎间盘切除减压融合术的58例神经根型颈椎病患者... 目的:探究中药联合颈前路椎间盘切除减压融合术治疗神经根型颈椎病的临床疗效,术后使用中药是否能够促进患者康复。方法:回顾性分析2019年10月—2022年2月在中日友好医院脊柱外科行颈前路椎间盘切除减压融合术的58例神经根型颈椎病患者。58例患者被分为单纯手术组和手术联合中药组,其中单纯手术组32例,手术联合中药组26例。记录并分析手术时间、术中出血量、术后并发症情况及术前与术后不同时间点纳入患者的疼痛视觉模拟评分(VAS)、颈椎功能障碍指数(NDI)。结果:所有手术均顺利完成且患者均完成术后12个月内的随访。单纯手术组和手术联合中药组的VAS评分在术后1个月、3个月(3.00±0.75 vs 2.00±1.00;2.00±1.00 vs 2.00±1.00)差异有统计学意义(P<0.05);NDI评分在术后3个月、6个月(15.00±3.00 vs 13.00±3.00;13.94±1.90 vs 12.50±3.00)差异有统计学意义(P<0.05)。结论:颈前路椎间盘切除减压融合术可解除患者颈神经受压状态,术后联合使用中药可以改善患者症状,缓解术后疼痛,促进神经功能恢复。 展开更多
关键词 神经根型颈椎病 中医中药 颈前路椎间盘切除减压融合术 临床疗效
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不同颈椎前路椎间融合系统内固定颈椎的生物力学变化 被引量:1
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作者 王强 李世芸 +1 位作者 熊鹰 李甜甜 《中国组织工程研究》 CAS 北大核心 2024年第6期821-826,共6页
背景:针对在颈椎病治疗过程中,颈椎前路椎间融合系统Zero-P系统在术后会出现螺钉松动、断裂等问题,研发出一种新型Low-P系统。目的:对比新型Low-P与Zero-P型颈椎前路椎间融合系统对颈椎邻近节段生物力学的影响,并对内固定系统进行应力分... 背景:针对在颈椎病治疗过程中,颈椎前路椎间融合系统Zero-P系统在术后会出现螺钉松动、断裂等问题,研发出一种新型Low-P系统。目的:对比新型Low-P与Zero-P型颈椎前路椎间融合系统对颈椎邻近节段生物力学的影响,并对内固定系统进行应力分析,从而为临床治疗提供理论参考。方法:建立无损颈椎C_(1)-C_(7)节段完整模型,基于模型有效性,建立在C_(4)-C_(5)节段置入Low-P型(Z型Low-P和H型Low-P)与Zero-P型系统的有限元模型,在前屈、后伸、侧弯和旋转4种工况下,分析置入器械、邻近椎体髓核、纤维环与终板的应力分布情况。结果与结论:(1)置入Low-P型与Zero-P型内固定器械后,H型Low-P系统活动范围大,Z型Low-P系统最大应力值较小,Zero-P型对邻近节段髓核最大应力较大,终板最大应力较小;(2)3种内固定系统对邻近节段纤维环的影响相接近;(3)Zero-P型内固定系统螺钉应力远大于Low-P系统;(4)提示相比Zero-P型内固定系统,新型Low-P系统降低了钢板和螺钉的应力值,可以降低螺钉松动、内固定系统失效等问题;Low-P型系统对于邻近椎间盘髓核的应力较小,可降低邻近节段椎间盘退变;此次研究结果可为Low-P型内固定系统的临床研究提供理论依据。 展开更多
关键词 颈椎前路内固定系统 Low-P型 Zero-P型 颈椎 生物力学 有限元分析
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零切迹融合器联合钛板椎间融合器治疗多节段脊髓型颈椎病
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作者 钟建斌 胡勇 +5 位作者 储振涛 董伟鑫 袁振山 孙肖阳 朱秉科 赖欧杰 《中国骨伤》 CAS CSCD 2024年第12期1188-1195,共8页
目的:探讨零切迹融合器联合钛板椎间融合器治疗多节段脊髓型颈椎病的临床疗效。方法:回顾性分析2016年1月至2020年1月手术治疗的107例多节段脊髓型颈椎病患者,根据手术方式不同分为Hybrid组和对照组。Hybrid组54例,男42例,女12例;年龄33... 目的:探讨零切迹融合器联合钛板椎间融合器治疗多节段脊髓型颈椎病的临床疗效。方法:回顾性分析2016年1月至2020年1月手术治疗的107例多节段脊髓型颈椎病患者,根据手术方式不同分为Hybrid组和对照组。Hybrid组54例,男42例,女12例;年龄33~77 (57.3±9.5)岁;C_(3)-C_(6) 20例,C_4-C_(7) 27例,C_(3)-C_(7) 7例;采用零切迹融合器联合钛板椎间融合器内固定术。对照组53例,男34例,女19例;年龄36~79(57.8±8.9)岁;C_(3)-C_(6) 17例,C_4-C_(7) 27例,C_(3)-C_(7) 9例,采用钛板椎间融合器内固定术。比较两组手术时间、术中出血量和并发症情况,采用视觉模拟评分(visual analogue scale,VAS)、日本骨科学会(Japanese Orthopedic Association,JOA)评分和颈椎功能障碍指数(neck disability index,NDI)评估临床症状恢复情况;测量并比较颈椎前凸角(cervical lordosis,CL)、颈椎矢状垂直轴(cervical sagittal vertical axis,C-SVA)和T_(1)倾角(T_(1) slope,T_(1)S)以评估颈椎矢状面参数。结果:107例患者均获得随访,Hybrid组随访时间为24~64(31.7±18.4)个月,对照组随访时间为24~65(32.6±15.8)个月,两组随访时间比较,差异无统计学意义(P>0.05)。Hybrid组手术时间和出血量少于对照组(P<0.05)。两组末次随访颈部VAS、JOA评分和NDI均较术前明显改善(P<0.05)。两组手术前后颈部VAS、JOA和NDI评分组间比较,差异无统计学意义(P>0.05)。两组术后3个月及末次随访CL均较术前明显改善(P<0.05),两组手术前后T_(1)S和C-SVA组间比较,差异无统计学意义(P>0.05)。Hybrid组术后2例出现吞咽困难,对照组9例出现吞咽困难,两组比较差异有统计学意义(χ^(2)=5.112,P=0.024)。随访期间两组无内固定物松动、移位、断裂等并发症。结论:与钛板椎间融合器相比,零切迹融合器联合钛板椎间融合器治疗多节段脊髓型颈椎病可缩短手术时间和出血量,减少手术创伤及术后吞咽困难,有利于早期快速康复。 展开更多
关键词 多节段脊髓型颈椎病 外科手术 零切迹融合器 颈前路间盘切除植骨融合术
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小尾寒羊颈椎前路椎间盘切除融合模型的建立及评估
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作者 窦新雨 刘宇 +6 位作者 刘啸 祝斌 贾斐 王霖邦 金攻 沈飞 刘晓光 《中国实验动物学报》 CAS CSCD 北大核心 2024年第2期139-150,共12页
目的颈椎间盘突出症(cervical disc herniation,CDH)是骨科常见疾病之一,随着对该疾病研究的深入及颈椎内植物的发展,建立颈椎融合动物模型成为不可或缺的部分,目前国内对颈椎融合动物模型建立及评估的研究报道较少,本研究以期为颈椎融... 目的颈椎间盘突出症(cervical disc herniation,CDH)是骨科常见疾病之一,随着对该疾病研究的深入及颈椎内植物的发展,建立颈椎融合动物模型成为不可或缺的部分,目前国内对颈椎融合动物模型建立及评估的研究报道较少,本研究以期为颈椎融合相关研究提供完备的动物模型和内植物性能的评估方案。方法选择小尾寒羊,改良术式后行颈椎前路椎间盘切除融合术(anterior cervical discectomy and fusion,ACDF),将聚醚醚酮(polyetheretherketone,PEEK)椎间融合器(interbody fusion cage,Cage)(对照组)、3D打印钛合金Cage(实验组1)及新方法钛合金Cage(实验组2)分别植入每只羊的不同颈椎节段(C2/3~C4/5),术后行血液学检测、组织病理学分析评估手术恢复情况及材料生物安全性,利用X光、CT、Micro-CT及定量分析、硬组织切片染色、生物力学试验评估内植物的骨长入及骨融合情况。结果绵羊改良术式ACDF模型建立成功,血液学检测重要指标无显著性差异(P>0.05),组织病理学分析显示均无炎症细胞浸润等病理改变,内植物生物安全性良好,X光及CT显示内固定位置及椎间融合情况良好,术后3个月及6个月Micro-CT及定量分析表明,与PEEK Cage组相比,新方法钛合金Cage组及3D打印钛合金Cage组内部的骨体积/总体积、骨小梁数目显著性升高(P<0.01),骨小梁间距显著性降低(P<0.01),且新方法钛合金Cage组骨质长入更多(P<0.01),硬组织切片染色表明新方法钛合金Cage组及3D打印钛合金Cage组孔隙内有明显骨质长入且较为密实,结合较PEEK Cage组略好,生物力学试验显示,与PEEK Cage组相比,新方法钛合金Cage及3D打印钛合金Cage在一定程度上降低了颈椎屈伸、侧弯、扭转运动范围(P<0.05),同时增强了颈椎的稳定性,且新方法钛合金Cage更有优势(P<0.05)。结论建立绵羊改良术式ACDF模型后,利用合理有效的评估方法,证明了该模型的合理性及有效性,同时说明3种材料的Cage均显示出良好的生物安全性,新方法钛合金Cage及3D打印钛合金Cage较PEEK Cage的骨长入及骨融合性能更强,可增强颈椎的稳定性,且新方法钛合金Cage更有优势。 展开更多
关键词 颈椎前路椎间盘切除融合术 颈椎间盘突出症 绵羊模型 椎间融合器
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Baguera-C人工颈椎间盘置换与零切迹颈前路椎间融合治疗单节段颈椎病的疗效比较
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作者 姜海军 赵衍斌 +3 位作者 孙宇 夏天 杨枭雄 周非非 《骨科》 CAS 2024年第6期488-494,共7页
目的比较Baguera-C人工颈椎间盘置换与零切迹(Zero-P)颈前路椎间融合治疗单节段颈椎病的疗效。方法回顾性分析在北京大学第三医院手术治疗的单节段颈椎病病人42例,21例采用Baguera-C人工颈椎间盘置换的病人纳入置换组,21例采用Zero-P行... 目的比较Baguera-C人工颈椎间盘置换与零切迹(Zero-P)颈前路椎间融合治疗单节段颈椎病的疗效。方法回顾性分析在北京大学第三医院手术治疗的单节段颈椎病病人42例,21例采用Baguera-C人工颈椎间盘置换的病人纳入置换组,21例采用Zero-P行颈前路减压融合内固定术的病人纳入融合组。比较两组病人术前、术后3个月、末次随访时的日本骨科学会(JOA)评分、颈椎疼痛视觉模拟量表(VAS)评分、颈椎功能障碍指数(NDI)、颈椎曲度、C2~C7矢状面轴向距离(C-SVA)、T1倾斜角、手术节段的相邻节段活动度等。结果两组病人随访时间、手术时间和出血量比较,差异均无统计学意义(P>0.05)。置换组术后1例(4.76%)、融合组术后2例(9.52%)出现轻度吞咽困难,随访时症状逐渐缓解。在术前、术后3个月和末次随访这3个不同时间点,两组病人的JOA评分、VAS评分、NDI进行组内两两比较,差异均有统计学意义(P<0.05),但组间差异无统计学意义(P>0.05);末次随访时置换组的JOA评分改善率优于融合组(95.19%±9.08%vs.81.54%±27.35%),差异有统计学意义(P<0.05)。置换组术后3个月、末次随访的T1倾斜角均大于术前,差异有统计学意义(P<0.05);置换组4例(19.05%)出现异位骨化,均未影响置换节段的活动度。融合组术后3个月的颈椎曲度明显大于术前,末次随访时的上邻椎活动度明显大于术前及术后3个月,末次随访时的下邻椎活动度明显大于术前,差异均有统计学意义(P<0.05)。融合组病人末次随访时有2例未融合,融合率为90.48%。末次随访融合组下邻椎活动度大于置换组,差异有统计学意义(P<0.05)。结论Baguera-C人工颈椎间盘置换与Zero-P颈前路减压融合治疗单节段颈椎病均能取得较好的临床疗效,但Baguera-C人工颈椎间盘能够有效模拟椎间盘功能,保护小关节运动,有效减少相邻节段的退变发生。 展开更多
关键词 颈椎病 椎间盘置换术 Baguera-C 零切迹 颈前路减压融合术
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3D-CT指导单孔分体脊柱内镜精准切除钩状突减压颈神经的安全性研究
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作者 刘昌震 王红艳 +4 位作者 孙兆忠 孙宁 冯志萌 李洒 李岳飞 《中国疼痛医学杂志》 CAS CSCD 北大核心 2024年第7期515-521,共7页
目的:观测钩状突尖端(uncinate process tip,UPT)、椎弓根峡部和颈神经之间的位置关系,为单孔分体脊柱内镜辅助颈椎前路椎间盘切除减压融合术中钩状突精准切除实现颈神经彻底减压提供临床数据参考。方法:选取2016年8月至2021年1月滨州... 目的:观测钩状突尖端(uncinate process tip,UPT)、椎弓根峡部和颈神经之间的位置关系,为单孔分体脊柱内镜辅助颈椎前路椎间盘切除减压融合术中钩状突精准切除实现颈神经彻底减压提供临床数据参考。方法:选取2016年8月至2021年1月滨州医学院附属医院的26例神经根型颈椎病病人资料,并在Mimics21.0上观测C3~4至C7~T1相关参数:UPT分别至UPT所在矢状面的颈神经前缘前后距离(a)、UPT所在矢状面的颈神经下缘垂直距离(b)、颈神经起点上缘左右距离(c)、颈神经起点上缘垂直距离(d)、颈神经起点下缘垂直距离(e)、椎弓根峡部外侧缘前后距离(f)、椎弓根峡部外侧缘左右距离(g)、颈神经外展角(∠A)、前倾角(∠B)。结果:C_(3~4)至C_(7)~T_(1),同节段不同性别、不同侧别之间差异无统计学意义;同节段b、e之间差异无统计学意义,表明减压UPT所在矢状面的颈神经下缘即可实现颈神经起点下缘减压;随着C_(3~4)至C_(7)~T_(1)节段降低,a逐渐减小;b、d、e、g、∠A、∠B逐渐增加;c、f先增加后减小(P<0.05)。结论:以UPT作为重要骨性标志点,明确颈神经减压范围并精准切除钩状突。UPT向前(0.9±0.5)mm至(2.3±1.3)mm至椎弓根峡部外侧缘,向外磨透钩状突,可完成UPT至椎弓根区出口处颈神经腹侧减压;向上(5.5±2.1)mm至(8.0±3.0)mm、向内(1.1±0.5)mm至(1.9±0.9)mm分别磨除部分上位椎体和钩状突后外侧壁增生骨赘,可显露硬脊膜外侧缘和颈神经起点上缘,完成UPT至颈神经起点减压,为手术精准切除钩状突安全减压颈神经提供理论依据。 展开更多
关键词 3D-CT 单孔分体脊柱内镜 颈椎前路椎间盘切除减压融合术 钩状突尖端
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有限元法预测颈椎前路椎间盘切除融合螺钉置入位置对内固定稳定性的影响 被引量:1
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作者 季兴华 魏金政 +1 位作者 郝帅 邢泽军 《中国组织工程研究》 CAS 北大核心 2024年第30期4777-4782,共6页
背景:在颈椎前路椎间盘切除融合过程中,螺钉放置角度会影响内固定系统的稳定性。目的:有限元分析法预测不同螺钉放置角度对颈椎前路椎间盘切除融合过程中内固定系统应力的影响,寻找螺钉最佳放置角度。方法:采用三维重建法建立颈椎力学模... 背景:在颈椎前路椎间盘切除融合过程中,螺钉放置角度会影响内固定系统的稳定性。目的:有限元分析法预测不同螺钉放置角度对颈椎前路椎间盘切除融合过程中内固定系统应力的影响,寻找螺钉最佳放置角度。方法:采用三维重建法建立颈椎力学模型,模拟颈椎侧弯、直立和前屈等3种不同的工况。在SolidWorks 2017软件中,建立颈椎前路钢板和螺钉模型,根据螺钉的不同放置角度建模,a为内侧偏移,b为理想位置,c为外侧偏移,d为向下偏移,e为向上偏移。观察不同螺钉放置角度下内固定的应力分布,并记录其应力和位移。结果与结论:①构建全颈椎及前路钢板置入后的有限元模型,在相同工况下,钢板上螺钉的不同置入角度对脊柱生物力学改变无明显差别;②但微观数值显示,在侧弯工况下,向外偏移(c)螺钉位置的抗侧弯性能最好;在直立工况下,向下偏移(d)螺钉承载效果最好;在反屈工况下,向外偏移(c)螺钉抗屈效果最好;③在不同的运动工况下,内固定装置的固定效果是相对稳定的;当螺钉向内侧、外侧、向下或向上放置时,3种工况下的内固定效果相差10%,但位移变化较小;这说明在临床实际操作中同时满足承重、抗弯、抗屈的最佳螺钉位置是不存在的;④提示颈椎前路间盘切除融合术中钢板螺钉的置入方向对颈椎的力学稳定性影响不大;在颈椎侧屈、直立、前屈运动时,不同方向的螺钉角度对颈椎内固定装置的稳定性影响不大;因此在临床手术中无需刻意追求螺钉的置入方向。 展开更多
关键词 颈椎前路 椎体融合 生物力学 有限元法 内固定 螺钉放置
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