A review of ethnobotanical studies reveals over 500 medicinal plants in Mindanao,Philippines

Medicinal plants have long been used to treat various diseases in both indigenous and non-indigenous populations of Mindanao,Philippines.Here,we extracted data from ethnobotanical studies to compile a comprehensive list of these medicinal plants and identify how and for what purpose they are most commonly used.We identified 530 verified medicinal plant species across 372 genera in 118 families.The two most frequently cited species were Euphorbia hirta and Psidium guajava.The most represented family was Fabaceae and the most represented genus was Ficus.A total of 28 medicinal plant species are designated as threatened at the national or global level;of these,11 are endemic to the Philippines.Medicinal plant preparations most commonly use leaves for oral administration to treat various diseases such as digestive issues,including diarrhea.This study underscores the need for further ethnobotanical investigations,particularly in areas lacking records.It also emphasizes the need for conservation of threatened and endemic medicinal plants to ensure sustainable utilization of this valuable resource.

Physiology of medicinal and aromatic plants under drought stress

Drought poses a significant challenge,restricting the productivity of medicinal and aromatic plants.The strain induced by drought can impede vital processes like respiration and photosynthesis,affecting various aspects of plants’growth and metabolism.In response to this adversity,medicinal plants employ mechanisms such as morphological and structural adjustments,modulation of drought-resistant genes,and augmented synthesis of secondary metabolites and osmotic regulatory substances to alleviate the stress.Extreme water scarcity can lead to leaf wilting and may ultimately result in plant death.The cultivation and management of medicinal plants under stress conditions often differ from those of other crops.This is because the main goal with medicinal plants is not only to increase the yield of the above-ground parts but also to enhance the production of active ingredients such as essential oils.To elucidate these mechanisms of drought resistance in medicinal and aromatic plants,the current review provides a summary of recent literature encompassing studies on the morphology,physiology,and biochemistry of medicinal and aromatic plants under drought conditions.

Vasorelaxant effects of biochemical constituents of various medicinal plants and their benefits in diab

Endothelial function plays a pivotal role in cardiovascular health,and dysfunction in this context diminishes vasorelaxation concomitant with endothelial activity.The nitric oxide-cyclic guanosine monophosphate pathway,prostacyclin-cyclic adenosine monophosphate pathway,inhibition of phosphodiesterase,and the opening of potassium channels,coupled with the reduction of calcium levels in the cell,constitute critical mechanisms governing vasorelaxation.Cardiovascular disease stands as a significant contributor to morbidity and mortality among individuals with diabetes,with adults afflicted by diabetes exhibiting a heightened cardiovascular risk compared to their non-diabetic counterparts.A plethora of medicinal plants,characterized by potent pharmacological effects and minimal side effects,holds promise in addressing these concerns.In this review,we delineate various medicinal plants and their respective biochemical constituents,showcasing concurrent vasorelaxant and anti-diabetic activities.

Ethnobotanical and Phytochemical Study of Medicinal Plants Sold in the Markets of the City of N’Djamena

The use of medicinal plants occupies an important place in traditional Chadian medicine, this study was carried out with the aim of listing the medicinal plants sold in the markets of the city of N’Djamena, and knowledge of the medicinal flora Chad, such as the leaves of Guiera senegalensis in Arabic called Khibeche, the roots of Cassia occidentalis called Am kwala-Kinkéliba in Arabic;the bark of Khaya senegalensis (Desv) A. Juss called Muraї in Arabic and the seeds of Trigonella foenum-graecum called Helbé in Arabic in order to treat the most frequently cited diseases such as malaria, the common cold, mother and newborn care, and typhoid. Ethnobotanical surveys were conducted from September to December 2022, in three markets in the city of N’Djamena, based on individual interviews using a semi-structured questionnaire, with 30 herbalists and traditional practitioners. Phytochemical screening analyses of the organs of four plants were carried out in the chemistry and biology laboratory of the Faculty of Exact and Applied Sciences (FSEA) following a standard protocol established by [1] and slightly modified by [2] [3]. The results of the surveys identified 68 species divided into fifty-five (55) genera and twenty-seven (27) families, the most represented of which were Caesalpiniaceae (10 species), Mimosaceae (5 species) and Combretaceae (4 species). The leaves were the most commonly used parts (43%), with decoction (70%) the most frequently used method of preparation. The oral route was the most popular with 73% of recipes. The phytochemical study revealed a wealth of secondary metabolites such as Trapezoidal Sterols, Alkaloids, Tannins, Flavonoids, Free Quinones, Anthocyane, Anthraquinones, Saponosides and Heterosides. These results can be considered as a source of information for scientific research in the field of phytochemistry and pharmacology.

Hypoglycaemiac Medicinal Plants Used by Diabetics at CNHU-HKM

Introduction: Diabetes is a major public health problem. Medicinal plants are frequently used either combine with industrial treatment or exclusively, in Africa and particularly in Benin. Our study aims to identify the different medicinal plants used by diabetic patients at the CNHU-HKM. Method: we carried out a descriptive and analytical cross-sectional study. It took place at the University Clinic of Endocrinology, Metabolism and Nutrition of CNHU-HKM over a of 3 months period from 20th of June to 16th of September, 2022, over diabetic followed-up. Results: One hundred and seventy-three (173) patients were gathered using an anonymous inquiry form. In the study population, the age of the patients varied between 31 and 75 years with an average age of 59 +/− 1.43 years, women represented 59% with a sex ratio (male/female) of 0.69. Sixty-five (65) or 37.6% of the population had used medicinal plants. Among given reasons for using medicinal plants were, mainly the positiveness on a third party. Data analysis outcome twenty-nine species of plants belonging to twenty (20) botanical families, the most represented being the Annonaceae and Fabaceae. The most used species are Phyllanthus amarus (hlenwé in fon), Mangifera indica (mangatin in fon), Momordica charantia (gninsikin in fon), Combretum micranthum (kinkéliba in fon), and Picralima nitida (ayorkpè in fon). Most used parts of the plants are the leaves. The recipes are prepared mainly by infusion and are administered exclusively by mouth. Most of the patients who used the hypoglycaemic medicinal plants were satisfied and no adverse effects were reported by them. Conclusion: Hypoglycaemic medicinal plants could be subjected to pharmacognosy and marketed due to their richness in active components, after further toxicological studies.

Nature’s Pharmacy under Siege: Investigating Antibiotic Resistance Pattern in Endophytic Bacteria of Medicinal Plants

Antibiotic resistance poses a significant global health threat, necessitating a thorough understanding of its prevalence in various ecological contexts. Medicinal plants, renowned for their therapeutic properties, host endophytic bacteria that produce bioactive compounds. Understanding antibiotic resistance dynamics in these bacteria is vital for human health and antibiotic efficacy preservation. In this study, we investigated antibiotic resistance profiles in endophytic bacteria from five medicinal plants: Thankuni, Neem, Aparajita, Joba, and Snake plant. We isolated and characterized 113 endophytic bacteria, with varying resistance patterns observed against multiple antibiotics. Notably, 53 strains were multidrug-resistant (MDR), with 14 exhibiting extensive drug resistance (XDR). Thankuni-associated bacteria displayed 44% MDR and 11% XDR, while Neem-associated bacteria showed higher resistance (60% MDR, 13% XDR). Aparajita-associated bacteria had lower resistance (22% MDR, 6% XDR), whereas Joba-associated bacteria exhibited substantial resistance (54% MDR, 14% XDR). Snake plant-associated bacteria showed 7% MDR and 4% XDR. Genus-specific distribution revealed Bacillus (47%), Staphylococcus (21%), and Klebsiella (11%) as major contributors to MDR. Our findings highlight diverse drug resistance patterns among plant-associated bacteria and underscore the complexity of antibiotic resistance dynamics in diverse plant environments. Identification of XDR strains emphasizes the severity of the antibiotic resistance problem, warranting further investigation into contributing factors.

Combination Activity of Standard Antituberculosis Drugs and Extracts of Medicinal Plants Commonly Used in Traditional Treatment of Tuberculosis in Uganda

Introduction: Resistance to antituberculosis drugs and adverse drug reactions remain the leading causes of tuberculosis therapeutic failure globally. Despite the increasing acceptance of medicinal plant use in combination with conventional antituberculosis drugs in treatment of tuberculosis (TB) in Uganda, there is paucity of knowledge on their combination effect. Aim: This research aimed to determine combination activity of standard antituberculosis drugs with extracts of Zanthoxylum leprieurii Guill. & Perr. and Rubia cordifolia L., the two common antituberculosis medicinal plants in Uganda, against pansensitive (H37Rv) and multi-drug resistant (MDR) Mycobacterium tuberculosis strains. Materials and Methods: Two reference MTB strains (H37Rv and MDR strain) were inoculated on Middlebrook 7H11 medium containing a combination of standard antituberculosis drugs and methanol extracts of Z. leprieurii and R. cordifolia at varying concentrations. The number of colonies on the plates was observed and counted weekly for up to 8 weeks. In vitro combination activity was determined using proportion method. Mean percentage inhibition was calculated for the reduction of number of colonies on drug-extract combination medium in relation to drug-extract-free control medium. Results: Drug-extract combinations showed good combination activity against Mycobacterium tuberculosis strains when compared with individual standard anti-TB drugs. This was more exhibited against MDR strain. There was however a reduction in percentage inhibition when extracts were combined with ethambutol and streptomycin against H37Rv strain. Conclusions: Zanthoxylum leprieurii and Rubia cordifolia in combination with standard anti-TB drugs exhibited increased in vitro activity against Mycobacterium tuberculosis, especially MDR-TB strain. This justifies the local use of these plants in traditional treatment of tuberculosis especially in resistant cases in Uganda.

Ethnobotanical Study of Medicinal Plants Used for Treating Urinary Tract Infections in N’Djamena (Chad)

Introduction: Infection disease is a real publique health problem. The rise of resistance for modern antibiotic in infections treatment imposed us order alternatives. The study objective was to contribute in the knowledge of medicinal plants uses in urinary infections treatment in N’Djamena (Chad) in view for amelioration the traditional medicine in future. Methodology: The study was conducted in the city of N’Djamena in the Republic of Chad that interviewed 60 traditherapists on using 11 plants for urinary tract infections treatment. The methodology of this study consisted of the knowledge of medicinal plants that used by traditherapists, and the plants identification was done in the laboratory of IRED at Farcha. Results: A total of 60 traditherapists was interrogated on the plants used in the treatment of urinary tract infections among the population of N’Djamena. The majority of traditherapists interrogated in this study were male with the rate of 61.67% against female with the rate of 38.33%. The age range of traditherapists was between 20 to 80 years, 25 (41.67%) from the age range between 30 - 50 years and 35 (58.33%) in age range from 50 to 70 years. For the origin of their knowledge, the study showed that 72% of traditherapists inherited the knowledge from their family, while 15% inherited from the family and from training. The ethnic groups of the traditherapists were Sara (16%), Maraba (12%) and Massa (11%). According to the results, 18.33% were illiterates, 49% attended primary school and 33.34% the secondary school. Our study found that 11 species of plants belonging to 11 families were used in the treatment of urinary tract infection and the Ziziphus spina-christi was the most represented. According to traditherapists the Ziziphus spina-christi, Cassia obovata and Euphorbia hirta were the most frequent plants used in the urinary tract infections treatment. The parts of plants used in the treatment were leaves and bark, grained leaves and entire plants with the proportion of 50%, 16.67 and 15% respectively. Conclusion: This study revealed that the medicinal plants are variously used in the treatment of infection urinary tract in the city of N’Djamena.

Traditional Use of Medicinal Plants Confirmed by the Baka in Southern and Eastern Cameroon

The limitations of biomedecine to provide effective solutions to certain pandemics has led many people to turn to alternative therapies. These palliative solutions, particularly phytomedecines, are much sought after for disease prevention and treatment. The Baka, a group of forest-dwelling people, hold knowledge on how wild plants can be effective in treating many illnesses. However, the greatest challenge for the identification of traditional medicines depends on the veracity of the information provided during ethnobotanic surveys by user populations. The present study describes forest plants used by the Baka and confirmed by them as being employed for traditional medicine. We carried out ethnobotanical surveys between 2019 and 2021 in 221 households within four districts of the Eastern and Southern Region of Cameroon. We used indices of significant use and performance applied to all mentioned species, alongside searches in the literature. The statistical tools used to distinguish the different groups/districts is Pearson’s X2 test. A total of 378 plant species were identified of 270 genera and 85 families. Ethnobotanical indices allowed to identify the most confirmed and efficient plants for several health problems. A pairwise comparison of these indices showed a significant correlation with a p-value < 2.2e-16 and a dissimilarity distance less than 0.5. Some plants selected are widely cited in other regions and/or countries for the same health problems. The presence of active molecules responsible for their biological activity was also proven, justifying their use in traditional medicine. This paper examines the potential to enhance the value of Cameroon’s pharmacopeia by integrating various ethnobotanical indices. It aims to discover new therapeutic molecules and develop improved traditional products from the diverse plant species documented. The findings indicate opportunities to advance both local and global healthcare solutions.

Potential efficacy and mechanism of medicinal plants on chronic kidney disease-associated vascular calcification:a review

Vascular calcification is a crucial risk factor that affects the incidence and mortality of cardiovascular disease in chronic kidney disease patients.Modern medicine relies on calcium-phosphorus binding agents,calcium mimetics,active vitamin D,and hemodialysis to prevent and treat vascular calcification,however,their efficacy is unsatisfactory and adverse reactions often occur.Medical plant therapy can act as an integrative regulator in patients with chronic kidney disease-associated vascular calcification,which can significantly improve patients’symptoms,but its specific mechanism has not been fully elucidated yet.In this paper,we reviewed the domestic and international theoretical studies on the pathogenesis mechanism of chronic kidney disease-associated vascular calcification in recent years,summarized eight active ingredients of medicinal plants as well as four compound formulas for improving chronic kidney disease-associated vascular calcification,and explored the mechanism of action of herbal medicine,which will provide a new strategy for promoting the prevention and treatment of vascular calcification.

In silico prospective analysis of the medicinal plants activity on the CagA oncoprotein from Helicobacter pylori

BACKGROUND Colonization with Helicobacter pylori(H.pylori)has a strong correlation with gastric cancer,and the virulence factor CagA is implicated in carcinogenesis.Studies have been conducted using medicinal plants with the aim of eliminating the pathogen;however,the possibility of blocking H.pylori-induced cell differentiation to prevent the onset and/or progression of tumors has not been addressed.This type of study is expensive and time-consuming,requiring in vitro and/or in vivo tests,which can be solved using bioinformatics.Therefore,prospective computational analyses were conducted to assess the feasibility of interaction between phenolic compounds from medicinal plants and the CagA oncoprotein.AIM To perform a computational prospecting of the interactions between phenolic compounds from medicinal plants and the CagA oncoprotein of H.pylori.METHODS In this in silico study,the structures of the phenolic compounds(ligands)kaempferol,myricetin,quercetin,ponciretin(flavonoids),and chlorogenic acid(phenolic acid)were selected from the PubChem database.These phenolic compounds were chosen based on previous studies that suggested medicinal plants as non-drug treatments to eliminate H.pylori infection.The three-dimensional structure model of the CagA oncoprotein of H.pylori(receptor)was obtained through molecular modeling using computational tools from the I-Tasser platform,employing the threading methodology.The primary sequence of CagA was sourced from GenBank(BAK52797.1).A screening was conducted to identify binding sites in the structure of the CagA oncoprotein that could potentially interact with the ligands,utilizing the GRaSP online platform.Both the ligands and receptor were prepared for molecular docking using AutoDock Tools 4(ADT)software,and the simulations were carried out using a combination of ADT and AutoDock Vina v.1.2.0 software.Two sets of simulations were performed:One involving the central region of CagA with phenolic compounds,and another involving the carboxy-terminus region of CagA with phenolic compounds.The receptor-ligand complexes were then analyzed using PyMol and BIOVIA Discovery Studio software.RESULTS The structure model obtained for the CagA oncoprotein exhibited high quality(C-score=0.09)and was validated using parameters from the MolProbity platform.The GRaSP online platform identified 24 residues(phenylalanine and leucine)as potential binding sites on the CagA oncoprotein.Molecular docking simulations were conducted with the three-dimensional model of the CagA oncoprotein.No complexes were observed in the simulations between the carboxy-terminus region of CagA and the phenolic compounds;however,all phenolic compounds interacted with the central region of the oncoprotein.Phenolic compounds and CagA exhibited significant affinity energy(-7.9 to-9.1 kcal/mol):CagA/kaempferol formed 28 chemical bonds,CagA/myricetin formed 18 chemical bonds,CagA/quercetin formed 16 chemical bonds,CagA/ponciretin formed 13 chemical bonds,and CagA/chlorogenic acid formed 17 chemical bonds.Although none of the phenolic compounds directly bound to the amino acid residues of the K-Xn-R-X-R membrane binding motif,all of them bound to residues,mostly positively or negatively charged,located near this region.CONCLUSION In silico,the tested phenolic compounds formed stable complexes with CagA.Therefore,they could be tested in vitro and/or in vivo to validate the findings,and to assess interference in CagA/cellular target interactions and in the oncogenic differentiation of gastric cells.

Study on Planting Techniques of Medicinal Plant Anchusa italica Retz

Anchusa italica Retz.,a perennial herb,has the effects of clearing away heat and toxic materials,and killing parasites to relieve itching.It is mainly used for breast abscess,sore swollen poison,scabies and so on,and serves as one of the commonly used medicinal materials in Uygur medicine.A.italica is distributed in Iran,Europe,Afghanistan and Kazakhstan.It is cultivated in China,and Xinjiang mostly imports it from Pakistan.This study belongs to the technical field of traditional Chinese medicine planting.The planting method solves the technical problems of sowing,field management,harvesting and processing of A.italica.

Analysis of wild medicinal vascular plant resources and diversity in Dabie Mountains, Anhui Province

Dabie Mountains are located at the junction of Anhui,Henan and Hubei provinces in the East of China.With its varied altitude,climate,and soil texture,Dabie Mountains are extremely rich in wild plant resources.The 12th Traditional Chinese Medicine(TCM)Resources Scientific Expedition Team of Shenyang Pharmaceutical University conducted a study on wild vascular plants resources,especially medicinal vascular plants,through field investigation,literature review and specimen identification.There were 472 species of vascular plants belonging to 347 genera and 125 families collected during July 2018 in this area,of which 424 species were medicinal vascular plants,accounting for 89.83%of the total.From the perspective of medicinal parts,most of the medicinal plants there have values in their roots and rhizomes,as well as the whole plants.The efficacy and characteristics of these pharmaceutical dimensions were also summarized and analyzed in detail.Besides,among the wild vascular plants collected,the most dominant families with the biggest numbers of species are Compositae,Lamiaceae,Liliaceae,Rosaceae,Leguminosae,Ranunculaceae,Saxifragaceae and Polygonaceae,and the dominant genus are Viola and Sedum.In terms of life form,perennial herbs are dominant,accounting for 55.72%of the total species,followed by some annual(or biennial)herbs,shrubs and lianas.Finally,recommendations are put forward for strengthening the protection and utilization of wild medicinal plant resources in Dabie Mountains.

Recent trends of machine learning applied to multi-source data of medicinal plants

In traditional medicine and ethnomedicine,medicinal plants have long been recognized as the basis for materials in therapeutic applications worldwide.In particular,the remarkable curative effect of traditional Chinese medicine during corona virus disease 2019(COVID-19)pandemic has attracted extensive attention globally.Medicinal plants have,therefore,become increasingly popular among the public.However,with increasing demand for and profit with medicinal plants,commercial fraudulent events such as adulteration or counterfeits sometimes occur,which poses a serious threat to the clinical outcomes and interests of consumers.With rapid advances in artificial intelligence,machine learning can be used to mine information on various medicinal plants to establish an ideal resource database.We herein present a review that mainly introduces common machine learning algorithms and discusses their application in multi-source data analysis of medicinal plants.The combination of machine learning algorithms and multi-source data analysis facilitates a comprehensive analysis and aids in the effective evaluation of the quality of medicinal plants.The findings of this review provide new possibilities for promoting the development and utilization of medicinal plants.

Mechanisms of medicinal plants in the treatment of diabetic wound

Wound repair is noticeably prolonged in a diabetic state due to a faulty inflammatory process and an underlying neuropathy.Several medicinal plants and their products have been of prime importance for the management of wounds over the years.Various mechanisms whereby medicinal plants elicit their action in wound repair are revealed and some plants are proven to be experimentally effective in enhancing wound closure and achieving healing.The mechanisms identified include hyperglycemic control,alleviation of physiological inflammation,controlled oxidative stress,infection control,and influence on gene expression.Information in this review was sourced from research and review articles in electronic databases such as Web of Science,Scopus,PubMed,and Google Scholar.

The role of selected medicinal plants from Iranian traditional medicine for the treatment of fatigue in metabolic syndrome

Background:Fatigue is a symptom of metabolic disorders such as metabolic syndrome,which is currently increasing in the world.There is no specific medication for fatigue,but in many cases,such as in metabolic disorders,it can be relieved by treating the underlying causes.Oxidative stress and inflammation are associated with fatigue and metabolic syndrome.Other mechanisms in metabolic syndrome are also involved in causing fatigue.Objective:The aim of this study was to investigate the role of selected medicinal plants from Iranian traditional medicine(ITM)in improving fatigue in patients with metabolic syndrome.Methods:ITM is one of the most ancient systems of medicine.In this article,we first explained fatigue,its types,and treatment from the perspective of ITM and then introduced a list of medicinal plants used in ITM to treat fatigue.Next,we reviewed the biological effects of these plants effective in treating the manifestations of the metabolic syndrome based on a search of electronic databases.Results:They have antioxidant,anti-inflammatory,and anti-diabetic activities.Among them,Matricaria chamomilla L.,Laurus nobilis L.,Origanum majorana L.,Vitex agnus-castus L.,Lawsonia inermis L.,Anethum graveolens L.,and Pistacia terebinthus L.improve the lipid profile and reduce dyslipidemia.Also,the antihypertensive effects of Matricaria chamomilla,Laurus nobilis,and Origanum majorana have been proven.Conclusion:These plants prevent fatigue and disease progression by countering oxidative stress and inflammation and affecting the properties of the metabolic syndrome.

An Overview of Nanoparticles from Medicinal Plants: Synthesis, Characterization and Bio-Applications

Presenting and definition the most important points about nanoparticles for medicinal plants and the most important vital applications of them. The scoping review was performed according to systemic style. The research articles included the selected studies dealing with primary information on nanotechnology and medicinal plants published between 2000 and 2023. The search was at grassroots platforms such as Web of Science and PubMed. Many studies correlated the properties of plants’ nanoparticles such as stability, surface area, and high reactivity, and their small size. It was found that nanoparticles (NPs) have size ranging from some nanometers to 100 nm and their morphology is controlled because of their tiny size, NPs have a big surface area, which makes them suitable for many applications. Green nanotechnology has the potential to become an industry with very high green credentials as it is increasingly commercialized. In general, nanoparticles derived from medicinal plants offer a promising avenue for various bio-applications. Their green synthesis, biocompatibility, and potential therapeutic properties make them an attractive area of research with the potential to impact fields ranging from medicine to agriculture.

Medicinal plants and phytomedicines are used to treat or prevent illnesses in Sudan: a review

Traditional medicine is a reliable source for treating many diseases in Sudan.It is widely recognized in Sudan,as no Sudanese house is devoid of medicinal herbs.The Sudanese people and their historical stock of knowledge are distinguished by their knowledge and the many applications of herbs in treatment.This reference paper aims to collect all the available information about the use of medicinal plants in Sudan to treat disease or prevent it.Sudanese medicinal plants include a variety of plants and there are many medicinal applications for these plants in the world.According to the information reached by the paper,there are many therapeutic medical applications of these plants in the treatment of various bacterial infections,including digestive diseases,malaria,diabetes,rheumatic pain,respiratory diseases,jaundice,urinary tract infections,wounds,cancer and various microbial infections,according to the information reached by the paper.This reference is for a few groups of Sudanese medicinal plants such as tamarind,hibiscus,Acacia nilotica,Combretum hartmannianum,and Guiera senegalensis,etc.This review article also showed that these plants contain many biologically active substances as active ingredients,including flavonoids,saponins,alkaloids,stimulants,terpenes,tannins,fatty acids and essential oils.Even though Sudanese people use herbal medicine to treat a wide range of illnesses,more research is needed to show that these plants are safe and effective for people to use.For example,phytochemical analysis,biochemical activity tests and toxicology studies should be done to show that these plants are safe and effective for people to use.

An Overview of the Use of Medicinal Plants in Regenerative Dentistry

Aim: The oral cavity has the particularity to host multiple hard and soft tissues, in this paper, we will discuss the current therapies that lead to cell differentiation by regenerative therapies and the future alternatives proposed by medicinal plants and all the regenerative potential of these different tissues. Material and Methods: A detailed review of the literature through the various search engines: Scopus, PubMed, google scholar, Cochrane, etc., uses the selected keywords to explore the effect of the regenerative potential of several medicinal plants. Results: Through our research, we have proceeded to sort different medicinal plants, according to their repairing and regenerative potential on the different tissues of the oral cavity. Conclusion: Future studies are conceivable to explore the opportunities and potential provided by medicinal plants in the field of regenerative dentistry.

Phytochemical Screening of Some Medicinal Plants in Al Jouf, KSA

The utilization of ethnobotanical and phytochemical investigations in the discovery of novel medications is beneficial. Screening for phytochemicals is an important step in detecting the bioactive ingredients of medicinal plants which are used in conventional therapy. For the first time, 23 medicinal plants utilized in Saudi Arabian traditional therapy were examined. From August 2020 to July 2021, ethnobotanical fieldwork was conducted. There was some plant species identified, divided into pertinent families. Standard procedures were used to screen these medicinal plants for the occurrence of glycosides, alkaloids, saponins, resins, saponins, tannins, and flavonoids. Among the medicinal plants used, the most common phytochemicals were alkaloids (95.65%), glycosides (86.96%), saponin (82.61%), tannins (73.91%), flavonoids (56.52%), and resin (52.17%). The least widely distributed chemicals, on the other side, were resins. Trigonella foenum-graecum L., Pimpinella anisum L., and Cuminum cyminum L. seeds were shown to contain all six categories of secondary metabolites. The ethnographic importance of these medicinal plants is consistent with the content of secondary metabolites.