Looking up Prescriptions to Treat Infectious Disease:Anti-epidemic Books of Medical Formularies and Epidemic Prevention and Control in the Qing Dynasty

Copying,compiling,publishing,disseminating,and referencing anti-epidemic books of medical formularies were common activities during the outbreak of epidemics in the Qing dynasty.Its emergence,motivated by epidemic disease again and again,was important component parts of epidemic prevention and control.They played a unique role as media on affairs such as treating patients suffering from infectious diseases,mobilizing peoples to make contributions to anti-epidemic activities,integrating and popularizing knowledge of epidemic prevention.Anti-epidemic books of medical formularies were important to link peoples,things,and substances related with epidemic prevention and control,and were a kind of motivation to actively deal with the infectious disease,control the epidemic,and maintain health.Compared to other common measures,anti-epidemic books of medical formularies participated in many prevention and control practices deeply,which actually built a low cost,spontaneous,dispersed and non-institutional system to respond to epidemic,and the system had characteristics of stronger conductibility,bigger coverage area,and better external benefits.

Network Pharmacology, Molecular Docking and Experimental Exploring Molecular Mechanisms of Yinqiao Anti-Epidemic Formula in Regulating Mucosal Immune System of Respiratory Tract

[Objectives]To explore the molecular mechanisms of Yinqiao anti-epidemic formula(YQAEF)in regulating mucosal immune system of respiratory tract.[Methods]The active components of YQAEF were obtained from the TCMSP database,and RMIS targets were obtained from the GeneCards database.A"YQAEF components-RMIS targets-pathways"network was constructed by analyzing the above data to screen core targets for molecular docking verification.A mouse model of acute upper respiratory tract infection(AURI)was developed.Based on the experimental models,the key pathway target genes screened by network pharmacology were verified in vivo.[Results]The main active components of YQAEF involved in the regulation of the RMIS included quercetin,acetic acid,and raffinose.Key targets,such as angiotensin-converting enzyme(ACE),galactosidase alpha(GLA),matrix metalloproteinase 2(MMP2),Serpin Family E Member 1(SERPINE1),and myeloperoxidase(MPO)and important viral infection and endocrine resistance signaling pathways were included in the regulation of the RMIS with YQAEF.Molecular docking assays showed that the key targets had good binding activities with the components of YQAEF.Based on the results of network pharmacology,key target proteins in ACE,GLA,MMP2,SERPINE1,and MPO were selected for experimental verification.The results showed that ACE/ACE2 and MPO expressions were increased in the oral and throat mucosa of the AURI mice.Under YQAEF treatment,the expression levels of ACE/ACE2 and MPO were decreased.[Conclusions]This study revealed the mechanism of YQAEF in the regulation of RMIS,which is associated with multiple components,targets,and pathways.Further experiments confirmed that YQAEF interfered with MPO and ACE/ACE2 signaling pathways to regulate the RMIS in the oral and throat mucosa tissue of mice with AURI,and provide a new direction for exploring the potential antiviral mechanism of YQAEF.

Understanding the Global Identification with China’s Stories: A Cross-Cultural Perspective

Cross-cultural storytelling is a primary way for humankind to seek mutual recognition of value orientations between cultures,which facilitates the ability to jointly address the problems of human existence in the context of globalization.In this study,we conducted an interview survey of 6,130 respondents who were college students or graduates from 107 countries.The results show that there were a number of cross-cultural values embodied in China’s stories seen by the respondents as part of a common vision for the future of humankind and widely identified guidance on collaborative responses to global challenges.These cross-cultural values are common prosperity,ecological harmony,individual-collective integration,the urgency of global peace,as well as respect for multicultural and indigenous development paths.

Comparison between seismic analysis of twisting and regular 52-story towers considering soil-structure interaction

A dynamic analysis of both twisting and regular towers is carried out to determine the results of considering soil-structure interaction(SSI)on high-rise buildings.In addition,the difference between the seismic performance of using twisting towers over regular ones is investigated.The twisting tower is a simulation of the Evolution Tower(Moscow).The towers’skeletons consist of RC elements and rest on a reinforced concrete piled-raft foundation.The soil model is considered as multi-layered with the same soil properties as the zone chosen for the analysis(New Mansoura City,Egypt).The only difference between both towers is their shape in elevation.The whole system is modelled and analyzed in a single step as one full 3D model,which is known as the direct approach in SSI.All analyses are carried out using finite-element software(Midas GTS NX).Dynamic output responses due to three records of seismic loads are proposed and presented in some graphs.Based on the results,it is concluded that SSI has a considerable effect on the dynamic response of tall buildings mainly because of the foundation flexibility,as it leads to lengthening the vibration period,increasing the story drift and the base shear for both cases.

英语绘本融入Story time板块的教学尝试

英语绘本作为一种教学资源,因其图片鲜活、语料丰富、文化多元、内涵深刻而成为Story time板块强有力的补充。英语绘本融入Story time板块的教学,需要从六要素着眼,找准“融合点”;以主题情境助力,调整“匹配度”;以人物线串起任务,捕捉“突破点”。

基于英语核心素养的“Story time”教学新尝试

“Story time”板块是英语教材各单元的核心。教师结合“Story time”板块的特点,以课堂教学为载体来发展学生的语言能力、培养学生的思维品质、提升学生的学习能力、增强学生的文化意识,是提升学生英语学科核心素养的一项重要内容,也是当今小学英语课堂教学的新趋势。

基于主题意义的Story time板块课后作业设计

对主题意义的探究是小学英语教学的核心,而基于主题意义的作业设计是对课堂教学的补充和延伸。教师要基于主题意义探索Story time板块的课后作业设计,设计主题化、趣味化、生活化、层次化、实践化的课后作业,并通过合作与评价的方式,培养和激发学生对英语学习的兴趣,帮助学生深化对主题意义的理解,提高学生的综合语言运用能力,发展学生的思维品质,促进学生核心素养的形成和发展。

Research on Strategies for Enhancing the Ability of Chinese German Learners to Tell Chinese Stories Through Short Videos

In the age of new media,short videos play an increasingly important role in international cultural exchange.However,German learners often encounter challenges when producing and sharing short videos due to factors such as technology and language proficiency.Such challenges can affect the professionalism and attractiveness of the videos.This study focuses on German learners at the University of Shanghai for Science and Technology.The aim of this study is to investigate students’experiences in producing short videos,identify issues through surveys and interviews,and concentrate on editing skills,language proficiency,and intercultural communication abilities.It proposes strategies for developing these skills and aims to provide insights for German and other foreign language learners in telling Chinese stories using short videos.

Study on the Influence of Aspect Ratio on the Seismic Response and Overturning Resistance of a New Staggered Story Isolated Structure

The aspect ratio of the structure has a significant impact on the overall stability of the ultra high-rise building. A large aspect ratio of the structure increases the risk of overturning and reduces the lateral stiffness of the structure, leading to significant tensile and compressive stresses in the isolated bearings. To study the effect of aspect ratio on the seismic response and overturning resistance of a new staggered story isolated structure, three models with different aspect ratios were established. Nonlinear time-history analysis of the three models was conducted using ETABS finite element software. The results indicate that the overturning moment and overturning resistance moment of the superstructure in the new staggered story isolated structure increase with an increasing aspect ratio. However, the increase in the overturning moment of the superstructure is much greater than the increase in the overturning resistance moment, resulting in a decrease in the overturning resistance ratio of the superstructure with an increasing aspect ratio. The overturning moment and overturning resistance moment of the substructure in the new staggered story isolated structure decrease with an increasing aspect ratio. However, the decrease in the overturning moment of the substructure is greater than the decrease in the overturning resistance moment, leading to an increase in the overturning resistance ratio of the substructure with an increasing aspect ratio. The decrease in the overturning resistance ratio of the superstructure in the new staggered story isolated structure is much greater than the increase in the overturning resistance ratio of the substructure. Therefore, as the aspect ratio of the overall structure increases, the overturning resistance ratio of the superstructure and the entire structure decreases.

Progressive Collapse Resistance of a New Staggered Story Isolated System

A new staggered isolated system developed from the mid-story isolated system is the new staggered story isolated system. There are not many studies on this structure currently. In this study, an 18-story new staggered story isolated system model is established using SAP2000. The dynamic nonlinear dynamic alternate method is used to analyze the structure against progressive collapse. Results show that the structure has good resistance to progressive collapse, and there is no progressive collapse under each working condition. The progressive collapse does not occur for the case of removing only one vertical structural member of the new staggered of isolated system. The side column has big influence on this isolated structures’ progressive collapse;the removal of vertical structural member of the isolation layer has less impact on the structure than the removal of the bottom vertical structural member. After the removing of the member, the internal force of the structure will be redistributed, and the axial force of the adjacent columns will change obviously, showing a trend of “near large and far small”.

Writing the Silenced Female Body, Scrutinizing the Grand Narrative of Colonization and Decolonization: The Body in Zoë Wicomb’s David’s Story

David’s Story by Zoë Wicomb addresses the complexities of representing female suffering and the limitations of traditional historical narratives in capturing the experiences of marginalized bodies.It challenges the grand narratives of national history by emphasizing the indispensable role of women’s experiences.Through characters like Dulcie and Rachael,Wicomb portrays the female body as a site of resistance and resilience,highlighting the need for more nuanced and inclusive ways of documenting history.Underscoring the inexpressibility of trauma and the limitations of language and representation,the novel self-reflexively acknowledges its own aporia of completing the narrative,embodying the ongoing struggle to capture the full breadth of human experience.

A Study of a Moral Dilemma Stories Teaching Model Focusing on the Development of Higher-Order Thinking --"Synthetic polymers" as an example

Cultivating students'higher-order thinking is one of the important goals of modern education,and innovative teaching model is an effective way to achieve this goal.Aiming at the inadequacy of the existing moral dilemma stories approach in the transformation of knowledge and behavior,this research constructs a new Project Based Learning-Ethical Dilemma Stories(PBL-EDS)Teaching Model applicable to China's secondary education stage based on the innovative features of the moral dilemma stories approach on the core competencies,taking the chemistry subject as an example to carry out practice,and puts forward suggestions for the implementation of the teaching model.Chemistry as an example to carry out the practice,and suggestions are made for the implementation of the teaching model.

Practical Paths for Integrating“Stories of China”in the New Era into Ideological and Political Education in Universities

As socialism with Chinese characteristics enters a new era,ideological and political education in universities is presented with new opportunities.Telling the“Stories of China”is not only necessary for inheriting and promoting the excellent traditional Chinese culture but also an important way to build the socialist core value system and cultivate qualified builders of socialism.Effectively integrating the“Stories of China”with the ideological and political theory courses in universities is of great significance for guiding students to establish correct worldviews,outlooks on life,and values.This paper focuses on the practical paths of integrating the“Stories of China”with ideological and political theory in universities,deeply analyzes the existing integration mechanisms,principles to follow,and challenges faced,and explores innovative paths.It aims to provide a new perspective for ideological and political education in universities,promote the comprehensive development of students,and provide solid theoretical support for cultivating qualified socialist builders.

Story Map在高中英语读后续写教学实践中的应用——以2023年全国高考新课标Ⅰ卷读后续写为例

读后续写作为新高考英语写作的新题型,可以有效地考查学生的阅读能力和写作水平,而使用Story Map有助于培养学生的续写思维和写作能力。英语教师应深入分析读后续写题型,认真探索以Story Map促进高中英语叙事文本类读后续写教学的途径,采取绘制Story Map、挖掘续写突破点、合理想象续编故事、明确标准以评促写等做法,帮助学生出色完成续写。

Seismic Response of Adjacent Structure to Inter-Story Isolated Structure

Currently, land resources are becoming more and more constrained and structures are getting closer to each other. To investigate the seismic response of inter-story isolated structure to adjacent structure, models considering no soil-structure interaction (SSI), considering soil-structure interaction (SSI), and considering structure-soil-structure interaction (SSSI) were established. Nonlinear seismic response comparative analysis was conducted by varying the spacing between adjacent structure and inter-story isolated structure, as well as the weight of adjacent structure, under different earthquake inputs, in order to obtain the structural response characteristics. The results indicate that the inter-story drift and inter-story shear of the inter-story isolated structure without considering SSI are smaller than those considering SSI and SSSI. The inter-story drift and inter-story shear of the inter-story isolated structure considering SSSI are further affected compared to that of the inter-story isolated structure considering only SSI. As the spacing between adjacent structure and inter-story isolated structure increases, the influence of adjacent structure on inter-story isolated structure decreases. The variation in the spacing between the two structures has a negligible effect on the isolation layer of the inter-story isolated structure. With the increase in the weight of adjacent structure, the influence of adjacent structure on inter-story isolated structure becomes more significant. The increasing weight of adjacent structure has an increasing effect on the Isolation layer of the inter-story isolated structure.

SEISMIC DAMAGE PREDICTION ON MULTI-STORYBRIOK BUILDINGS WITH TWO FRAME-SHEAR-WALL-SUPPORTED STORIES

This paper presents a method for searching the weak story by using the ultimate shear force coefficient on the multi-story brick buildings with two frame-shear-wall-supported stories. The method of seismic damage prediction is discussed according to different weak stories. When the first story is t theweak one,the damage state of the building can be determined by the displacement ratio. The prediction method is also used in a practical engineering project.

China's Anti-epidemic Diplomacy Boosts Global Public Health Governance

In 2020 with a pandemic sweeping the world,global political and economic orders seriously disrupted and tens of millions of human lives threatened,the spread of the novel coronavirus is the world's number one challenge.China has efficiently organized domestic epidemic control and vigorously promoted international cooperation in the battle against the pandemic by advancing head-of-state diplomacy.In this ongoing crisis,China has actively led the way for global public health governance,promoted the building of a community with common health for mankind,and demonstrated the actions of a responsible major country.

The Logic of Self-Justification of China’s Anti-Epidemic Effectiveness

The COVID-19 outbreak in 2020 is a syndrome of economic,social and governance crises.It is not only a test of the medical and health system of a country or a region,but also a test of the emergency management system and the comprehensive governance capacity.Based on the complexity of epidemic prevention and control,no single factor can explain and respond to the"exceptional status"of epidemic prevention and control.Only by applying the"Theory of History Resultant Force",establishing systematic thinking,and comprehensively reviewing and analyzing can we comprehensively and objectively clarify its pros and cons.Having taken advantage of the party’s leadership,the nationwide system,and the Socialism with Chinese characteristics with a broad mass base and strong material support,China has achieved obvious results in a relatively short period of time in the process of epidemic prevention and control.It provides other countries or regions with Chinese experience,and Chinese wisdom for anti-epidemic efforts.

Acquisition and Dissemination of Anti-Epidemic Medical Prescriptions During the Outbreaks in the Qing Dynasty of China

During the epidemics in the Qing dynasty,many medical professionals,nonprofessionals,and social organizations collected and sorted medical prescriptions related to infectious diseases.These people also compiled,published,disseminated,and consulted related medical formularies.The above historical event can be viewed as the construction and dissemination of medical knowledge.They edited and published medical formularies on infectious diseases with lower cost and in flexible ways by taking the initiative and giving full scope to creativity.Diverse anti-epidemic medical prescriptions from these medical formularies can be used for infectious diseases in the event of the outbreaks.However,the therapeutic effects of classical prescriptions and folk recipes cannot be regarded as the same.The wide circulation of anti-epidemic medical prescriptions and medical formularies was essentially a process of epidemic prevention resource allocation.Not only did it enable many nonprofessionals to participate in epidemic prevention and control,but it also enhanced awareness,knowledge,and capacity for epidemic prevention at the individual level.At the same time,due to the uneven quality and individual differences in the physical fitness and condition of the prescriptions and formularies,they had the capacity of causing inconveniences to the readers or patients.

Hero Hua Mulan With a Thousand Faces:Why Chinese Stories Can Move the World?Evidence From a Global Cross-Cultural Interview Survey

While people from Western countries do not always understand of the underlying cultural values of most Chinese stories,the Hua Mulan story has gained significant recognition from Western audiences.Therefore,it would be quite beneficial if we could understand the key elements that have contributed to the success of the Hua Mulan story so that we can employ similar elements in other intercultural communication programs and promote the communication and dissemination of cultures between China and the rest of the world.According to the findings from the interviews of 6,130 respondents from 107 countries,we found that the Hua Mulan story gains global acceptance because it represents a story of“a hero with a thousand faces,”which embodies the integration of Chinese traditions and contemporary spirit through sharing a global meaning while responding to various culturally common challenges.Five key cultural value dimensions are responsible for this Chinese story’s cross-cultural affinity and influence,which helped it win recognition and empathy worldwide.The five key cultural value dimensions are loyalty and patriotism,the courage to take responsibility,compatibility of individualism and collectivism,respondence to the multicultural appeal,and hero growth.These dimensions are then generalized as the value identity orientation grounded in a Global Shared Meaning(GSM)in this study.