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Fiber optic monitoring of an anti-slide pile in a retrogressive landslide 被引量:3
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作者 Lei Zhang Honghu Zhu +1 位作者 Heming Han Bin Shi 《Journal of Rock Mechanics and Geotechnical Engineering》 SCIE CSCD 2024年第1期333-343,共11页
Anti-slide piles are one of the most important reinforcement structures against landslides,and evalu-ating the working conditions is of great significance for landslide mitigation.The widely adopted analytical methods... Anti-slide piles are one of the most important reinforcement structures against landslides,and evalu-ating the working conditions is of great significance for landslide mitigation.The widely adopted analytical methods of pile internal forces include cantilever beam method and elastic foundation beam method.However,due to many assumptions involved in calculation,the analytical models cannot be fully applicable to complex site situations,e.g.landslides with multi-sliding surfaces and pile-soil interface separation as discussed herein.In view of this,the combination of distributed fiber optic sensing(DFOS)and strain-internal force conversion methods was proposed to evaluate the working conditions of an anti-sliding pile in a typical retrogressive landslide in the Three Gorges reservoir area,China.Brillouin optical time domain reflectometry(BOTDR)was utilized to monitor the strain distri-bution along the pile.Next,by analyzing the relative deformation between the pile and its adjacent inclinometer,the pile-soil interface separation was profiled.Finally,the internal forces of the anti-slide pile were derived based on the strain-internal force conversion method.According to the ratio of calculated internal forces to the design values,the working conditions of the anti-slide pile could be evaluated.The results demonstrated that the proposed method could reveal the deformation pattern of the anti-slide pile system,and can quantitatively evaluate its working conditions. 展开更多
关键词 anti-slide pile Multi-sliding surface Pile-soil interface Brillouin optical time domain reflectometry (BOTDR) Geotechnical monitoring Reservoir landslide
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Anchoring Depth Research of Anti-Slide Piles of Anchor Bar in Soil 被引量:6
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作者 Xunchang Li,Yuming Men School of Geological Engineering and Surveying Engineering,Chang’an University,Xi’an 710054,China. 《地学前缘》 EI CAS CSCD 北大核心 2009年第S1期182-182,共1页
The model test result of earth force in the side of anti-slide pile of anchor bars was introduced.There are three groups of the tests.The loads were on the back side of the slope in two groups.The other one was loaded... The model test result of earth force in the side of anti-slide pile of anchor bars was introduced.There are three groups of the tests.The loads were on the back side of the slope in two groups.The other one was loaded just behind the pile by the jack.In order to get the force of the soil,some earth-pressure boxes were used to get the earth pressure on the side of the piles.The part of the max pressure and the earth pressure was mainly focused under the slip line 展开更多
关键词 anti-slide PILE of ANCHOR BAR model test ANCHORING DEPTH SLIP line
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Design of micropiles to increase earth slopes stability 被引量:4
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作者 孙书伟 王家臣 卞晓琳 《Journal of Central South University》 SCIE EI CAS 2013年第5期1361-1367,共7页
A methodology was proposed for the design of micropiles to increase earth slopes stability. An analytic model based on bearn-colurnn equation and an existing P-y curve method was set up and used to find the shear capa... A methodology was proposed for the design of micropiles to increase earth slopes stability. An analytic model based on bearn-colurnn equation and an existing P-y curve method was set up and used to find the shear capacity of the micropile. Then, a step-by-step design procedure for stabilization of earth slope with rnicropiles was introduced, involving six main steps: 1) Choosing a location for the rnicropiles within the existing slope; 2) Selecting micropile cross section; 3) Estimating length of rnicropile; 4) Evaluating shear capacity of mieropiles; 5) Calculating spacing required to provide force to stabilize the slope; 6) Designing the concrete cap beam. The application of the method to an embankment landslide in Qinghai Province was described in detail. In the final design, three rows of rnicropiles were adopted as a group and a total of 126 rnicropiles with 0.23 m in diameter were used. The micropile length ranged between 15 and 18 m, with the spacing 1.5 m at in-row direction. The monitoring data indicate that slope movement has been effectively controlled as a result of the slope stabilization measure, which verifies the reasonability of the design method. 展开更多
关键词 micropiles earth slope stabilization lateral response analysis design method P-y curve
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Shaking table test for reinforcement of soil slope with multiple sliding surfaces by reinforced double-row anti-slide piles 被引量:6
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作者 WU Hong-gang PAI Li-fang 《Journal of Mountain Science》 SCIE CSCD 2022年第5期1419-1436,共18页
Despite the continuous advancements of engineering construction in high-intensity areas,many engineering landslides are still manufactured with huge thrust force,and double-row piles are effective to control such larg... Despite the continuous advancements of engineering construction in high-intensity areas,many engineering landslides are still manufactured with huge thrust force,and double-row piles are effective to control such large landslides.In this study,large shaking table test were performed to test and obtain multi-attribute seismic data such as feature image,acceleration,and dynamic soil pressure.Through the feature image processing analysis,the deformation characteristics for the slope reinforced by double-row piles were revealed.By analyzing the acceleration and the dynamic soil pressure time domain,the spatial dynamic response characteristics were revealed.Using Fast Fourier Transform and half-power bandwidth,the damping ratio of acceleration and dynamic soil pressure was obtained.Following that,the Seism Signal was used to calculate the spectral displacement of the accelerations to obtain the regional differences of spectral displacement.The results showed that the overall deformation mechanism of the slope originates from tension failure in the soil mass.The platform at the back of the slope was caused by seismic subsidence,and the peak acceleration ratio was positively correlated with the relative pile heights.The dynamic soil pressure of the front row piles showed an inverted"K"-shaped distribution,but that of the back row piles showed an"S"-shaped distribution.The predominant frequency of acceleration was 2.16 Hz,and the main frequency band was 0.7-6.87 Hz;for dynamic soil pressure,the two parameters became 1.15 Hz and 0.5-6.59 Hz,respectively.In conclusion,dynamic soil pressure was more sensitive to dampening effects than acceleration.Besides,compared to acceleration,dynamic soil pressure exhibited larger loss factors and lower resonance peaks.Finally,back row pile heads were highly sensitive to spectral displacement compared to front row pile heads.These findings may be of reference value for future seismic designs of double-row piles. 展开更多
关键词 Double row anti-slide piles multislide surface landslide Shaking table test ACCELERATION Dynamic soil pressure Dynamic response characteristic
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Interval finite element method and its application on anti-slide stability analysis 被引量:3
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作者 邵国建 苏静波 《Applied Mathematics and Mechanics(English Edition)》 SCIE EI 2007年第4期521-529,共9页
The problem of interval correlation results in interval extension is discussed by the relationship of interval-valued functions and real-valued functions. The methods of reducing interval extension are given. Based on... The problem of interval correlation results in interval extension is discussed by the relationship of interval-valued functions and real-valued functions. The methods of reducing interval extension are given. Based on the ideas of the paper, the formulas of sub-interval perturbed finite element method based on the elements are given. The sub-interval amount is discussed and the approximate computation formula is given. At the same time, the computational precision is discussed and some measures of improving computational efficiency are given. Finally, based on sub-interval perturbed finite element method and anti-slide stability analysis method, the formula for computing the bounds of stability factor is given. It provides a basis for estimating and evaluating reasonably anti-slide stability of structures. 展开更多
关键词 interval correlation interval extension computational precision interval finite element method anti-slide stability
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Behaviour of Batter Micropiles Subjected to Vertical and Lateral Loading Conditions 被引量:1
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作者 Binu Sharma Zakir Hussain 《Journal of Geoscience and Environment Protection》 2019年第2期206-220,共15页
Micropiles are drilled and grouted piles having diameter between 100 to 250 mm. Due to its small diameter, it is suitable for low headroom and limited work area conditions. It can be installed without noise nuisance, ... Micropiles are drilled and grouted piles having diameter between 100 to 250 mm. Due to its small diameter, it is suitable for low headroom and limited work area conditions. It can be installed without noise nuisance, without vibrations to surrounding soils and structures and without disruption to the production operations in industries which makes micropiles suitable for underpinning and seismic retrofitting of structures. It is necessary to therefore understand the behaviour of micropiles under different loading conditions. This work is on vertical and battered micropiles with different length/diameter ratio (L/D) subjected to vertical and lateral loading conditions. Batter angles had a significant influence on both the vertical and lateral load carrying capacity. The ultimate vertical load was found to increase upto a 30&#176;batter. The ultimate lateral load was found to increase significantly with increasing L/D ratios upto an L/D ratio of 30 for vertical and 48 for battered piles, beyond which the increase was found to be not significant. In general, negative battered micropiles offered more lateral resistance than positive battered micropiles. The results of the study indicated that the ultimate load capacity and mode of failure of the micropiles are a function of the angle of batter, direction of batter and the L/D ratio for vertically and laterally loaded micropiles. 展开更多
关键词 BATTER micropiles VERTICAL LOAD LATERAL LOAD LENGTH to DIAMETER Ratio Failure Mechanism
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New method of designing anti-slide piles——the strength reduction FEM 被引量:3
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作者 Zheng Yingren Zhao Shanyi +1 位作者 Lei Wenjie Tang Xiaosong 《Engineering Sciences》 EI 2010年第3期2-11,共10页
At present,the thrust of an anti-slide pile can be worked out with some calculation methods. However,the resistance in front of the pile,the distributions of resistance and thrust,and appropriate pile length cannot be... At present,the thrust of an anti-slide pile can be worked out with some calculation methods. However,the resistance in front of the pile,the distributions of resistance and thrust,and appropriate pile length cannot be easily obtained. In this paper,the authors applied the strength-reduction finite element method (FEM) to several design cases of anti-slide piles. Using this method,it is possible to take the pile-soil interactions into consideration,obtain reasonable resistance in front of pile and the distributions of thrust and resistance,and reasonable lengths of anti-slide piles. In particular,the thrust and resistance imposed on embedded anti-slide piles can be calculated and composite anti-slide pile structures such as anchored piles and braced piles can be optimized. It is proved through the calculation examples that this method is more reliable and economical in the design of anti-slide pile. 展开更多
关键词 strength reduction method finite element method anti-slide piles sub-grade reaction embedded piles
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Centrifuge and numerical modeling of h-type anti-slide pile reinforced soil-rock mixture slope 被引量:1
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作者 ZHANG Hao XING Hao-feng +1 位作者 XUE Dao-rui TANNANT Dwayne 《Journal of Mountain Science》 SCIE CSCD 2023年第5期1441-1457,共17页
Due to the loose structure,high porosity and high permeability of soil-rock mixture slope,the slope is unstable and may cause huge economic losses and casualties.The h-type anti-slide pile is regarded as an effective ... Due to the loose structure,high porosity and high permeability of soil-rock mixture slope,the slope is unstable and may cause huge economic losses and casualties.The h-type anti-slide pile is regarded as an effective means to prevent the instability of soilrock mixture slope.In this paper,a centrifuge model test was conducted to investigate the stress distribution of the h-type anti-slide pile and the evolution process of soil arching during the loading.A numerical simulation model was built based on the similar relationship between the centrifuge model and the prototype to investigate the influence factors of the pile spacing,anchored depth,and crossbeam stiffness,and some recommendations were proposed for its application.The results show that the bending moment distribution of the rear pile exhibits Wshaped,while for the front pile,its distribution resembles V-shaped.The soil arching evolution process during loading is gradually dissipated from bottom to top and from far to near.During the loading,the change of bending moment can be divided into three stages,namely,the stabilization stage,the slow growth stage,and the rapid growth stage.In engineering projects,the recommended values of the pile spacing,anchored depth,and crossbeam stiffness are 4.0d,2.0d,and 2.0EI,where d and EI are the diameter and bending stiffness of the h-type anti-slide pile respectively. 展开更多
关键词 Centrifugemodel test Numerical simulation h-type anti-slide pile Soil-rock mixture slop Soil arching
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Construction of Micropiles Using Pressure Techniques
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作者 Hussein Elarabi Amin Ahmed Abbas Soorkty 《Journal of Civil Engineering and Architecture》 2015年第1期45-50,共6页
This paper discusses the technique of casting concrete ofmicropiles with pressures and the consequence of comparisons with normal way of casting concrete (casting with gravity). Preliminary geotechnical studies have... This paper discusses the technique of casting concrete ofmicropiles with pressures and the consequence of comparisons with normal way of casting concrete (casting with gravity). Preliminary geotechnical studies have been made in specific area in Sudan to predict the soil parameters and then an experimental work has been done for an estimated number ofmicropiles with different diameters and different techniques of placing concrete with various amount of pressure. This study was carried out to learn the usefulness of this technique in the field of structural foundations in Sudan. Capacities of micropiles were compared in cases of non-pressure casting (normal way of casting concrete) and pressure casting. Through the results, it was found that the entry of pressure factor in the operation of casting concrete increases the capacities of micropiles. The increased value of ultimate load depends on the amount of pressure applied. 展开更多
关键词 micropilE load test pressure casting.
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软土地区水泥土墙后插微型桩复合支护结构加固机理及应用分析
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作者 邹振 蒋楠 《水电能源科学》 北大核心 2025年第1期52-56,共5页
水泥土墙后插微型桩为一种较为新型的支护结构型式,目前规范中暂无该类支护结构计算方法,且在工程应用与研究中较少。为此,描述了水泥土墙内置微型桩支护体系布置形式,采用有限元数值建模计算分析方法研究了水泥土墙后插微型桩复合支护... 水泥土墙后插微型桩为一种较为新型的支护结构型式,目前规范中暂无该类支护结构计算方法,且在工程应用与研究中较少。为此,描述了水泥土墙内置微型桩支护体系布置形式,采用有限元数值建模计算分析方法研究了水泥土墙后插微型桩复合支护结构加固机理,提出了后插微型桩复合支护结构体系稳定性理论计算方法,并结合深圳市某软土地区堤防工程进行了应用实例计算分析及监测数据验证。结果表明,微型桩主要承受轴向荷载,直至支护体系破坏桩身弯矩和剪力仍较小,其加固作用类似于锚栓;建立的复合支护结构计算简图及稳定性计算公式可实现支护结构稳定性计算;现场监测数据的反馈可得出该新型复合支护结构体系安全可靠;水泥土墙后置深层微型桩应用于软土地区堤防工程中综合性价比高,较大提高了水泥土墙抗滑移、抗倾覆能力,降低了工程造价,具有一定的推广价值。 展开更多
关键词 水泥土墙后插微型桩 加固机理 计算公式 复合支护结构 工程实例 监测数据
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Study of the seismic performance of hybrid A-frame micropile/MSE (mechanically stabilized earth) wall 被引量:2
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作者 Chen Yumin Zhang Zhichao Liu Hanlong 《Earthquake Engineering and Engineering Vibration》 SCIE EI CSCD 2017年第2期275-295,共21页
The Hybrid A-Frame Micropile/MSE (mechanically stabilized earth) Wall suitable for mountain roadways is put forward in this study: a pair of vertical and inclined micropiles goes through the backfill region of a hi... The Hybrid A-Frame Micropile/MSE (mechanically stabilized earth) Wall suitable for mountain roadways is put forward in this study: a pair of vertical and inclined micropiles goes through the backfill region of a highway MSE Wall from the road surface and are then anchored into the foundation. The pile cap and grade beam are placed on the pile tops, and then a road barrier is connected to the grade beam by connecting pieces. The MSE wall's global stability, local stability and impact resistance of the road barrier can be enhanced simultaneously by this design. In order to validate the serviceability of the hybrid A-frame micropile/MSE wall and the reliability of the numerical method, scale model tests and a corresponding numerical simulation were conducted. Then, the seismic performance of the MSE walls before and after reinforcement with micropiles was studied comparatively through numerical methods. The results indicate that the hybrid A-frame micropile/ MSE wall can effectively control earthquake-induced deformation, differential settlement at the road surface, bearing pressure on the bottom and acceleration by means of a rigid-soft combination of micropiles and MSE. The accumulated displacement under earthquakes with amplitude of 0.1-0.5 g is reduced by 36.3%-46.5%, and the acceleration amplification factor on the top of the wall is reduced by 13.4%, 15.7% and 19.3% based on 0.1, 0.3 and 0.5 g input earthquake loading, respectively, In addition, the earthquake-induced failure mode of the MSE wall in steep terrain is the sliding of the MSE region along the backslope, while the micropiles effectively control the sliding trend. The maximum earthquake-induced pile bending moment is in the interface between MSE and slope foundation, so it is necessary to strengthen the reinforcement of the pile body in the interface. Hence, it is proven that the hybrid A-frame micropile/MSE wall system has good seismic performance. 展开更多
关键词 MSE wall steep slope micropilE reinforcement measure sliding trend seismic performance
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Pre-Stressed Rope Reinforced Anti-Sliding Pile 被引量:1
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作者 XU Jun WANG Chenghua 《Wuhan University Journal of Natural Sciences》 EI CAS 2006年第4期887-891,共5页
Pre-stressed rope reinforced anti-sliding pile is a composite anti-sliding structure. It is made up of pre-stressed rope and general anti-sliding pile. It can bring traditional anti-sliding pile's retaining performan... Pre-stressed rope reinforced anti-sliding pile is a composite anti-sliding structure. It is made up of pre-stressed rope and general anti-sliding pile. It can bring traditional anti-sliding pile's retaining performance into full play, and to treat with landslide fast and economically. The difference between them is that the pre-stressed rope will transfix the whole anti- sliding pile through a prearranged pipe in this structure. The working mechanics, the design method and economic benefit are studied. The results show that the pre-stressed rope reinforced anti-sliding pile can treat with the small and middle landslides or high slopes well and possess the notable advantage of technology and economic. 展开更多
关键词 pre-stressed rope anti-sliding pile composite anti-sliding structure
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Application of strength reduction method to dynamic anti-sliding stability analysis of high gravity dam with complex dam foundation 被引量:3
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作者 Deng-hong CHEN Cheng-bin DU 《Water Science and Engineering》 EI CAS 2011年第2期212-224,共13页
Considering that there are some limitations in analyzing the anti-sliding seismic stability of dam-foundation systems with the traditional pseudo-static method and response spectrum method, the dynamic strength reduct... Considering that there are some limitations in analyzing the anti-sliding seismic stability of dam-foundation systems with the traditional pseudo-static method and response spectrum method, the dynamic strength reduction method was used to study the deep anti-sliding stability of a high gravity dam with a complex dam foundation in response to strong earthquake-induced ground action. Based on static anti-sliding stability analysis of the dam foundation undertaken by decreasing the shear strength parameters of the rock mass in equal proportion, the seismic time history analysis was carried out. The proposed instability criterion for the dynamic strength reduction method was that the peak values of dynamic displacements and plastic strain energy change suddenly with the increase of the strength reduction factor. The elasto-plastic behavior of the dam foundation was idealized using the Drucker-Prager yield criterion based on the associated flow rule assumption. The result of elasto-plastic time history analysis of an overflow dam monolith based on the dynamic strength reduction method was compared with that of the dynamic linear elastic analysis, and the reliability of elasto-plastic time history analysis was confirmed. The results also show that the safety factors of the dam-foundation system in the static and dynamic cases are 3.25 and 3.0, respectively, and that the F2 fault has a significant influence on the anti-sliding stability of the high gravity dam. It is also concluded that the proposed instability criterion for the dynamic strength reduction method is feasible. 展开更多
关键词 dynamic anti-sliding stability complex dam foundation dynamic strength reduction method instability criteria elasto-plastie model dynamic time history analysis gravity dam
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Study on the performance of the micropile-mechanically stabilized earth wall 被引量:1
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作者 ZHANG Zhi-chao Ronald Y.S.PAK +1 位作者 CHEN Yu-min LIU Han-long 《Journal of Mountain Science》 SCIE CSCD 2018年第4期825-844,共20页
The Micropile-Mechanically Stabilized Earth(MSE) wall, specially designed for mountain roads, is proposed to improve the MSE wall local stability, global stability and impact resistance of roadside barriers. Model tes... The Micropile-Mechanically Stabilized Earth(MSE) wall, specially designed for mountain roads, is proposed to improve the MSE wall local stability, global stability and impact resistance of roadside barriers. Model tests and the corresponding numerical modeling were conducted to validate the serviceability of the Micropile-MSE wall and the reliability of the numerical method. Then, a parametric study of the stress and deformation of Micropile-MSE wall based on the backfill strength and interfacial friction angle between backfill and backslope is conducted to evaluate its performance.The test results indicate that the surcharge-induced horizontal earth pressure, base pressure and lateral displacement of the wall panel of Micropile-MSE wall decrease. The corresponding numerical results are nearly equal to the measured values. The basic failure mode of MSE wall in steep terrain is the sliding of backfill along the backslope, while A-frame style micropiles are capable of preventing the sliding trend.The maximum resultant displacement can be decreased by 6.25% to 46.9% based on different interfacial friction angles, and the displacement canbe reduced by 6% ~ 56.1% based on different backfill strengths. Furthermore, the reduction increases when the interfacial friction angle and internal friction angle of backfill decrease. In addition, the lateral displacement of wall panel, the deformation of backfill decrease and the tension strain of geogrid obviously, which guarantees the MSE wall functions and provides good conditions for mountain roads. 展开更多
关键词 Mechanically stabilized earth wall Model test micropilE Numerical simulation Stress and deformation behavior
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Study on distribution rule of sliding pushing force and remnant resistant sliding force acting on anti-sliding pile 被引量:1
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作者 Qingyang YU Lei NIE 《Global Geology》 2006年第2期227-231,共5页
Anti-slide pile is one of the important methods to administer landslide geological disaster because of its advantages.It plays important role in administering landslide.It is a premise of reasonable economy and techno... Anti-slide pile is one of the important methods to administer landslide geological disaster because of its advantages.It plays important role in administering landslide.It is a premise of reasonable economy and technological advance to know the distribution rule and feature of the force between anti-sliding pile and surrounding rock.To determine the sliding force and remnant resistant sliding force,according to need of study,this paper sets up the geological model and mechanics model in term of a typical landslide,and analyzes the effect rule of sliding body distortion,strength and gravity to the pushing force and remnant resistant sliding force by use of the numerical model.The distribution rule of pushing force and remnant resistant sliding force of the type of landslide is given. 展开更多
关键词 anti-slide pile pushing force remnant resistant sliding force numerical model
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Sensitivity analysis of factors affecting gravity dam anti-sliding stability along a foundation surface using Sobol method
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作者 Bo Xu Shi-da Wang 《Water Science and Engineering》 EI CAS CSCD 2023年第4期399-407,共9页
The anti-sliding stability of a gravity dam along its foundation surface is a key problem in the design of gravity dams.In this study,a sensitivity analysis framework was proposed for investigating the factors affecti... The anti-sliding stability of a gravity dam along its foundation surface is a key problem in the design of gravity dams.In this study,a sensitivity analysis framework was proposed for investigating the factors affecting gravity dam anti-sliding stability along the foundation surface.According to the design specifications,the loads and factors affecting the stability of a gravity dam were comprehensively selected.Afterwards,the sensitivity of the factors was preliminarily analyzed using the Sobol method with Latin hypercube sampling.Then,the results of the sensitivity analysis were verified with those obtained using the Garson method.Finally,the effects of different sampling methods,probability distribution types of factor samples,and ranges of factor values on the analysis results were evaluated.A case study of a typical gravity dam in Yunnan Province of China showed that the dominant factors affecting the gravity dam anti-sliding stability were the anti-shear cohesion,upstream and downstream water levels,anti-shear friction coefficient,uplift pressure reduction coefficient,concrete density,and silt height.Choice of sampling methods showed no significant effect,but the probability distribution type and the range of factor values greatly affected the analysis results.Therefore,these two elements should be sufficiently considered to improve the reliability of the dam anti-sliding stability analysis. 展开更多
关键词 Gravity dam anti-sliding stability Sensitivity analysis Sobol method Latin hypercube sampling
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Mechanism of Ganlu Xiaodu MicroPill against COVID-19 based on network pharmacology and molecular docking method
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作者 Yu-Hui Kuang Xiao-Qi Chen +3 位作者 Qing Zhao Jia-Qi Liang Kang Xie Xin-Ju Chen 《Journal of Hainan Medical University》 2020年第16期1-7,共7页
Objective: To analyze the potential active components and molecular mechanism of Ganlu Xiaodu MicroPill in the treatment of COVID-19 by network pharmacology and molecular docking. Methods: the active chemical constitu... Objective: To analyze the potential active components and molecular mechanism of Ganlu Xiaodu MicroPill in the treatment of COVID-19 by network pharmacology and molecular docking. Methods: the active chemical constituents and action targets of Ganlu Xiaodu MicroPill were searched by TCMSP and BATMAN-TCM platform, and the key targets were matched with the COVID-19 targets searched by CTD database. The core targets were selected and analyzed by GO and KEGG enrichment analysis by R software to predict the action mechanism of traditional Chinese medicine compound. The key component sets were docked with 3CLpro and ACE2. Results: 138 active components and 53 key targets were obtained. There are 1298 items in GO biological process, 59 items in cell composition, 62 items in molecular function, and 120 items enriched in KEGG pathway. Results: molecular docking showed that the affinity of 20 chemical components such as quercetin, luteolin and kaempferol with ACE2 and 3CLpro was higher than that of ribavirin and chloroquine. Conclusion: Ganlu Xiaodu MicroPill may regulate and interfere with SARS-CoV-2 infection through antivirus, inhibition of inflammatory factors and regulation of immunity, which fully reflects the therapeutic advantages of multi-components, multi-targets and multi-pathways of traditional Chinese medicine. 展开更多
关键词 Ganlu Xiaodu micropill COVID-19 Network pharmacology Molecular docking
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甘露消毒丹加减治疗妊娠期肝内胆汁淤积综合征的临床效果
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作者 彭瑶 夏晓健 +2 位作者 陈瑾 梁艳 杨琦 《中国当代医药》 CAS 2024年第13期80-83,共4页
目的探讨甘露消毒丹加减治疗妊娠期肝内胆汁淤积综合征(ICP)的临床效果。方法选取2021年10月至2022年6月在江西省妇幼保健院就诊的60例ICP患者作为研究对象,根据随机数字表法分为对照组和研究组,每组各30例。对照组给予常规西药治疗,研... 目的探讨甘露消毒丹加减治疗妊娠期肝内胆汁淤积综合征(ICP)的临床效果。方法选取2021年10月至2022年6月在江西省妇幼保健院就诊的60例ICP患者作为研究对象,根据随机数字表法分为对照组和研究组,每组各30例。对照组给予常规西药治疗,研究组给予甘露消毒丹加减治疗。比较两组患者的瘙痒程度评分,胆红素[总胆红素(TBil)、间接胆红素(IBil)、结合胆红素(DBil)],肝功能[丙氨酸转氨酶(ALT)、天冬氨酸转氨酶(AST)],并对两组患者不良妊娠结局进行观察。结果研究组治疗后的皮肤瘙痒评分及TBil、IBil、DBil水平均低于对照组,差异有统计学意义(P<0.05);研究组的ALT、AST水平均低于对照组,差异有统计学意义(P<0.05);研究组的不良妊娠结局总发生率低于对照组,差异有统计学意义(P<0.05)。结论甘露消毒丹加减治疗ICP患者能改善患者临床症状及肝功能,缓解皮肤瘙痒程度,减少不良妊娠结局的发生。 展开更多
关键词 甘露消毒丹加减 妊娠期肝内胆汁淤积综合征 肝功能 临床疗效
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基于群桩基础改进的变径微型桩承载特征研究
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作者 任光明 李海涛 +3 位作者 王必杨 范荣全 董斌 罗毅 《水文地质工程地质》 CAS CSCD 北大核心 2024年第2期90-100,共11页
为改善输电杆塔微型桩基础的承载特性、降低用料成本,提出基于微型群桩改进的变径微型桩基础型式。通过高原山区等截面微型群桩原型试验与数值反演模型相互验证,对3种变径微型单桩进行模拟,并与微型群桩承载效果进行对比分析,揭示变径... 为改善输电杆塔微型桩基础的承载特性、降低用料成本,提出基于微型群桩改进的变径微型桩基础型式。通过高原山区等截面微型群桩原型试验与数值反演模型相互验证,对3种变径微型单桩进行模拟,并与微型群桩承载效果进行对比分析,揭示变径微型桩的承载特征与变形机理。结果表明:微型群桩基础(2×2单桩)由于承台和群桩效应的影响,其抗压和抗拔承载力分别大于和小于对应的单桩承载力总和;双扩径微型桩(扩径部分直径=2×等截面桩身直径)的极限抗拔和抗压承载力约为等截面微型桩的3.8倍和2.7倍,土体变形集中于扩径部位,且变形量较大,表现为多支点摩擦-端承桩特性;于桩顶增设承台可有效改善双扩径单桩的下压及水平承载性能,与未增设承台相比,承载力分别提高了2.1倍和2.2倍。研究表明,通过扩展部分桩径并增设承台使微型单桩性能提升至等截面群桩水平的方法可行,对送变电建设具有工程意义。 展开更多
关键词 送变电工程 等截面微型群桩 原型试验 数值模拟 变径微型桩 承载力特征
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施工顺序对微型钢管桩加固既有基础变形的影响试验研究
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作者 刘江涛 李存军 +3 位作者 于江华 张彦红 张春彬 孔纲强 《土木与环境工程学报(中英文)》 CSCD 北大核心 2024年第4期100-108,共9页
微型钢管桩由于具有施工效率高、对周围环境友好等技术优点,被广泛应用于既有建筑物的增层改造、加固及纠偏工程中。施工顺序会影响加固或纠偏效果,甚至影响建筑物的安全,然而围绕施工顺序对微型钢管桩加固既有基础的变形特性影响的研... 微型钢管桩由于具有施工效率高、对周围环境友好等技术优点,被广泛应用于既有建筑物的增层改造、加固及纠偏工程中。施工顺序会影响加固或纠偏效果,甚至影响建筑物的安全,然而围绕施工顺序对微型钢管桩加固既有基础的变形特性影响的研究仍相对不足。基于透明土材料和粒子图像测速(Particle Image Velocimetry,PIV)处理技术,开展不同沉桩顺序(逆时针、顺逆时针结合、Z字形及对称形)下既有基础微型桩加固的可视化模型试验,分析加固过程引起的桩周土体位移场变化,以及不同沉桩加固顺序对既有承台的影响规律,并确定最优的加固方案。结果表明,在试验条件下,承台面下方的桩对桩周的土体有挤密作用,在承台周边压桩时,承台面下方的桩周围土体位移较小,相对于无承台情况影响范围缩小42%,最大位移缩小36%;对称加固顺序相对最优,施工过程中对既有基础的抬升位移仅为最不利加固顺序时的56%。 展开更多
关键词 既有基础 微型钢管桩 透明土 加固顺序 位移场
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