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Classification and Comprehension of Software Requirements Using Ensemble Learning
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作者 Jalil Abbas Arshad Ahmad +4 位作者 Syed Muqsit Shaheed Rubia Fatima Sajid Shah Mohammad Elaffendi Gauhar Ali 《Computers, Materials & Continua》 SCIE EI 2024年第8期2839-2855,共17页
The software development process mostly depends on accurately identifying both essential and optional features.Initially,user needs are typically expressed in free-form language,requiring significant time and human re... The software development process mostly depends on accurately identifying both essential and optional features.Initially,user needs are typically expressed in free-form language,requiring significant time and human resources to translate these into clear functional and non-functional requirements.To address this challenge,various machine learning(ML)methods have been explored to automate the understanding of these requirements,aiming to reduce time and human effort.However,existing techniques often struggle with complex instructions and large-scale projects.In our study,we introduce an innovative approach known as the Functional and Non-functional Requirements Classifier(FNRC).By combining the traditional random forest algorithm with the Accuracy Sliding Window(ASW)technique,we develop optimal sub-ensembles that surpass the initial classifier’s accuracy while using fewer trees.Experimental results demonstrate that our FNRC methodology performs robustly across different datasets,achieving a balanced Precision of 75%on the PROMISE dataset and an impressive Recall of 85%on the CCHIT dataset.Both datasets consistently maintain an F-measure around 64%,highlighting FNRC’s ability to effectively balance precision and recall in diverse scenarios.These findings contribute to more accurate and efficient software development processes,increasing the probability of achieving successful project outcomes. 展开更多
关键词 Ensemble learning machine learning non-functional requirements requirement engineering accuracy sliding window
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An Investigation on Open-RAN Specifications:Use Cases,Security Threats,Requirements,Discussions
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作者 Heejae Park Tri-HaiNguyen Laihyuk Park 《Computer Modeling in Engineering & Sciences》 SCIE EI 2024年第10期13-41,共29页
The emergence of various technologies such as terahertz communications,Reconfigurable Intelligent Surfaces(RIS),and AI-powered communication services will burden network operators with rising infrastructure costs.Rece... The emergence of various technologies such as terahertz communications,Reconfigurable Intelligent Surfaces(RIS),and AI-powered communication services will burden network operators with rising infrastructure costs.Recently,the Open Radio Access Network(O-RAN)has been introduced as a solution for growing financial and operational burdens in Beyond 5G(B5G)and 6G networks.O-RAN promotes openness and intelligence to overcome the limitations of traditional RANs.By disaggregating conventional Base Band Units(BBUs)into O-RAN Distributed Units(O-DU)and O-RAN Centralized Units(O-CU),O-RAN offers greater flexibility for upgrades and network automation.However,this openness introduces new security challenges compared to traditional RANs.Many existing studies overlook these security requirements of the O-RAN networks.To gain deeper insights into the O-RAN system and security,this paper first provides an overview of the general O-RAN architecture and its diverse use cases relevant to B5G and 6G applications.We then delve into specifications of O-RAN security threats and requirements,aiming to mitigate security vulnerabilities effectively.By providing a comprehensive understanding of O-RAN architecture,use cases,and security considerations,thisworkserves as a valuable resource for future research in O-RAN and its security. 展开更多
关键词 O-RAN ARCHITECTURE use cases security issues security requirements security discussions
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Requirements ranking based on crowd-sourcing high-end product USs
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作者 MA Yufeng DOU Yajie +2 位作者 XU Xiangqian JIA Qingyang TAN Yuejin 《Journal of Systems Engineering and Electronics》 SCIE EI CSCD 2024年第1期94-104,共11页
Based on the characteristics of high-end products,crowd-sourcing user stories can be seen as an effective means of gathering requirements,involving a large user base and generating a substantial amount of unstructured... Based on the characteristics of high-end products,crowd-sourcing user stories can be seen as an effective means of gathering requirements,involving a large user base and generating a substantial amount of unstructured feedback.The key challenge lies in transforming abstract user needs into specific ones,requiring integration and analysis.Therefore,we propose a topic mining-based approach to categorize,summarize,and rank product requirements from user stories.Specifically,after determining the number of story categories based on py LDAvis,we initially classify“I want to”phrases within user stories.Subsequently,classic topic models are applied to each category to generate their names,defining each post-classification user story category as a requirement.Furthermore,a weighted ranking function is devised to calculate the importance of each requirement.Finally,we validate the effectiveness and feasibility of the proposed method using 2966 crowd-sourced user stories related to smart home systems. 展开更多
关键词 high-end product complex system crowd-sourcing user stories topic mining requirements ranking
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Autoantibodies against beta cells to predict early insulin requirements in pediatric patients with clinically diagnosed type 2 diabetes
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作者 Jorge M Molina Patricia G Medina +4 位作者 Rita A Gomez Julia R Herrera Nancy L Martínez Brenda Hernández Yesenia García 《World Journal of Diabetes》 SCIE 2024年第8期1717-1725,共9页
BACKGROUND Autoimmunity has emerged as a probable disease modifier in patients with clinically diagnosed type 2 diabetes mellitus(T2DM),that is,patients who have insulin resistance,obesity,and other cardiovascular ris... BACKGROUND Autoimmunity has emerged as a probable disease modifier in patients with clinically diagnosed type 2 diabetes mellitus(T2DM),that is,patients who have insulin resistance,obesity,and other cardiovascular risk factors,suggesting that the presence of glutamic acid decarboxylase(anti-GAD65),islet antigen 2(anti-IA2),and zinc transporter 8(anti-Zn8T)antibodies could have deleterious effects on beta cell function,causing failure and earlier requirement for insulin treatment.AIM To evaluate anti-GAD65,anti-IA2 and anti-Zn8T as predictors of early insulin requirement in adolescents with a clinical diagnosis of T2DM.METHODS This was a case–control study in patients with clinically diagnosed with T2DM(68 cases and 64 controls with and without early insulin dependence respectively),male and female,aged 12–18 years.Somatometry,blood pressure,glucose,insulin,C-peptide,glycated hemoglobin A1c,and lipid profiles were assessed.ELISA was used to measure anti-GAD65,anti-IA2,and anti-Zn8T antibodies.Descriptive statistics,Pearson'sχ2 test,Student's t test,and logistic regression was performed.P<0.05 was considered statistically significant.RESULTS There were 132 patients(53.8%female),with a mean age was 15.9±1.3 years,and there was a disease evolution time of 4.49±0.88 years.The presence of anti-GAD65,anti-IA2,and anti-Zn8T positivity was found in 29.5%,18.2%,and 15.9%,respectively.Dividing the groups by early or no insulin dependence showed that the group with insulin had a higher frequency of antibody positivity:anti-GAD65 odds ratio(OR):2.42(1.112–5.303,P=0.026);anti-IA2:OR:1.55(0.859–2.818,P=0.105);and anti-Zn8T:OR:7.32(2.039–26.279,P=0.002).CONCLUSION Anti-GAD65 positivity was high in our study.Anti-GAD65 and anti-Zn8T positivity showed a significantly depleted beta cell reserve phenotype,leading to an increased risk of early insulin dependence. 展开更多
关键词 DIABETES OBESITY Adolescents AUTOIMMUNITY Beta cell Insulin requirements
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How to implement a knowledge graph completeness assessment with the guidance of user requirements
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作者 ZHANG Ying XIAO Gang 《Journal of Systems Engineering and Electronics》 SCIE CSCD 2024年第3期679-688,共10页
In the context of big data, many large-scale knowledge graphs have emerged to effectively organize the explosive growth of web data on the Internet. To select suitable knowledge graphs for use from many knowledge grap... In the context of big data, many large-scale knowledge graphs have emerged to effectively organize the explosive growth of web data on the Internet. To select suitable knowledge graphs for use from many knowledge graphs, quality assessment is particularly important. As an important thing of quality assessment, completeness assessment generally refers to the ratio of the current data volume to the total data volume.When evaluating the completeness of a knowledge graph, it is often necessary to refine the completeness dimension by setting different completeness metrics to produce more complete and understandable evaluation results for the knowledge graph.However, lack of awareness of requirements is the most problematic quality issue. In the actual evaluation process, the existing completeness metrics need to consider the actual application. Therefore, to accurately recommend suitable knowledge graphs to many users, it is particularly important to develop relevant measurement metrics and formulate measurement schemes for completeness. In this paper, we will first clarify the concept of completeness, establish each metric of completeness, and finally design a measurement proposal for the completeness of knowledge graphs. 展开更多
关键词 knowledge graph completeness assessment relative completeness user requirement quality management
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Research Progress on Nutritional Requirements of Carp
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作者 Yina LU 《Asian Agricultural Research》 2024年第1期37-39,43,共4页
Carp is a temperate freshwater fish native to Asia,distributed in all regions of the world except Australia and South America.With the improvement of comprehensive and healthy breeding technology of carp,the unit yiel... Carp is a temperate freshwater fish native to Asia,distributed in all regions of the world except Australia and South America.With the improvement of comprehensive and healthy breeding technology of carp,the unit yield has been greatly increased mainly due to the exten-sive use of compound feed.In this study,the nutritional requirements of carp were summarized from the aspects of protein,amino acids,fat,carbohydrate,calcium and phosphorus,vitamins and taurine.This study provides a certain theoretical reference for scientific formula of carp feed. 展开更多
关键词 CARP Nutritional requirements Foreground
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Security and Privacy in Solar Insecticidal Lamps Internet of Things:Requirements and Challenges
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作者 Qingsong Zhao Lei Shu +3 位作者 Kailiang Li Mohamed Amine Ferrag Ximeng Liu Yanbin Li 《IEEE/CAA Journal of Automatica Sinica》 SCIE EI CSCD 2024年第1期58-73,共16页
Solar insecticidal lamps(SIL) can effectively control pests and reduce the use of pesticides. Combining SIL and Internet of Things(IoT) has formed a new type of agricultural IoT,known as SIL-IoT, which can improve the... Solar insecticidal lamps(SIL) can effectively control pests and reduce the use of pesticides. Combining SIL and Internet of Things(IoT) has formed a new type of agricultural IoT,known as SIL-IoT, which can improve the effectiveness of migratory phototropic pest control. However, since the SIL is connected to the Internet, it is vulnerable to various security issues.These issues can lead to serious consequences, such as tampering with the parameters of SIL, illegally starting and stopping SIL,etc. In this paper, we describe the overall security requirements of SIL-IoT and present an extensive survey of security and privacy solutions for SIL-IoT. We investigate the background and logical architecture of SIL-IoT, discuss SIL-IoT security scenarios, and analyze potential attacks. Starting from the security requirements of SIL-IoT we divide them into six categories, namely privacy, authentication, confidentiality, access control, availability,and integrity. Next, we describe the SIL-IoT privacy and security solutions, as well as the blockchain-based solutions. Based on the current survey, we finally discuss the challenges and future research directions of SIL-IoT. 展开更多
关键词 CHALLENGES Internet of Things(IoT) privacy and security security requirements solar insecticidal lamps(SIL)
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Operational requirements analysis method based on question answering of WEKG
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作者 ZHANG Zhiwei DOU Yajie +3 位作者 XU Xiangqian MA Yufeng JIANG Jiang TAN Yuejin 《Journal of Systems Engineering and Electronics》 SCIE CSCD 2024年第2期386-395,共10页
The weapon and equipment operational requirement analysis(WEORA) is a necessary condition to win a future war,among which the acquisition of knowledge about weapons and equipment is a great challenge. The main challen... The weapon and equipment operational requirement analysis(WEORA) is a necessary condition to win a future war,among which the acquisition of knowledge about weapons and equipment is a great challenge. The main challenge is that the existing weapons and equipment data fails to carry out structured knowledge representation, and knowledge navigation based on natural language cannot efficiently support the WEORA. To solve above problem, this research proposes a method based on question answering(QA) of weapons and equipment knowledge graph(WEKG) to construct and navigate the knowledge related to weapons and equipment in the WEORA. This method firstly constructs the WEKG, and builds a neutral network-based QA system over the WEKG by means of semantic parsing for knowledge navigation. Finally, the method is evaluated and a chatbot on the QA system is developed for the WEORA. Our proposed method has good performance in the accuracy and efficiency of searching target knowledge, and can well assist the WEORA. 展开更多
关键词 operational requirement analysis weapons and equipment knowledge graph(WEKG) question answering(QA) neutral network
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The Customer Requirements Analysis Method of Engineering Products Based on Multiple Preference Information
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作者 Guo Mao 《Proceedings of Business and Economic Studies》 2024年第1期204-209,共6页
To effectively evaluate the fuzziness of the market environment in product planning,a customer requirements analysis method based on multiple preference information is proposed.Firstly,decision-makers use a preferred ... To effectively evaluate the fuzziness of the market environment in product planning,a customer requirements analysis method based on multiple preference information is proposed.Firstly,decision-makers use a preferred information form to evaluate the importance of each customer requirement.Secondly,a transfer function is employed to unify various forms of preference information into a fuzzy complementary judgment matrix.The ranking vector is then calculated using row and normalization methods,and the initial importance of customer requirements is obtained by aggregating the weights of decision members.Finally,the correction coefficients of initial importance and each demand are synthesized,and the importance of customer requirements is determined through normalization.The development example of the PE jaw crusher demonstrates the effectiveness and feasibility of the proposed method. 展开更多
关键词 Product planning Customer requirements Importance ratings Multi-format information
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Empirical Analysis of Software Success Rate Forecasting During Requirement Engineering Processes 被引量:1
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作者 Muhammad Hasnain Imran Ghani +3 位作者 Seung Ryul Jeong Muhammad Fermi Pasha Sardar Usman Anjum Abbas 《Computers, Materials & Continua》 SCIE EI 2023年第1期783-799,共17页
Forecasting on success or failure of software has become an interesting and,in fact,an essential task in the software development industry.In order to explore the latest data on successes and failures,this research fo... Forecasting on success or failure of software has become an interesting and,in fact,an essential task in the software development industry.In order to explore the latest data on successes and failures,this research focused on certain questions such as is early phase of the software development life cycle better than later phases in predicting software success and avoiding high rework?What human factors contribute to success or failure of a software?What software practices are used by the industry practitioners to achieve high quality of software in their day-to-day work?In order to conduct this empirical analysis a total of 104 practitioners were recruited to determine how human factors,misinterpretation,and miscommunication of requirements and decision-making processes play their roles in software success forecasting.We discussed a potential relationship between forecasting of software success or failure and the development processes.We noticed that experienced participants had more confidence in their practices and responded to the questionnaire in this empirical study,and they were more likely to rate software success forecasting linking to the development processes.Our analysis also shows that cognitive bias is the central human factor that negatively affects forecasting of software success rate.The results of this empirical study also validated that requirements’misinterpretation and miscommunication were themain causes behind software systems’failure.It has been seen that reliable,relevant,and trustworthy sources of information help in decision-making to predict software systems’success in the software industry.This empirical study highlights a need for other software practitioners to avoid such bias while working on software projects.Future investigation can be performed to identify the other human factors that may impact software systems’success. 展开更多
关键词 Cognitive bias misinterpretation of requirements miscommunication software success and failure prediction decision making
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Requirement Engineering for E-Coaching in Higher Education
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作者 Essam Almuhsin Ben Soh +1 位作者 Alice Li Azmat Ullah 《Engineering(科研)》 CAS 2023年第5期275-290,共16页
This paper presents a requirement engineering for developing an e-coaching environment in the higher education sector. This research demonstrates that IT experts encounter challenges in establishing a system that matc... This paper presents a requirement engineering for developing an e-coaching environment in the higher education sector. This research demonstrates that IT experts encounter challenges in establishing a system that matches a university’s expectations, as they are usually uncertain about its goals and system requirements. The paper illustrates a business goal-focused requirement induction technique, which encompasses demonstrating the business procedures through Business Process Modelling Notation (BPMN), assessing the university goals via the tree diagram, and drawing out the system requirements from the university objectives through UML state diagrams. A case study of supporting the development of a new IT course is used as a case study and applied using BPMN. 展开更多
关键词 E-Coaching System requirements requirement Engineering E-Coaching Process Business Goals
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On the Assessment of Generative AI in Requirements Analysis and Modeling Tasks with UML:An Exploratory Study
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作者 Chong Wang Peng Liang +2 位作者 Xiaojian Li Jian Wang Zhong Luo 《计算机教育》 2023年第12期2-10,共9页
Generative AI is rapidly employed by software developers to generate code or other software artifacts.However,the analysis and assessment of generative AI with respect to requirements analysis and modeling tasks,espec... Generative AI is rapidly employed by software developers to generate code or other software artifacts.However,the analysis and assessment of generative AI with respect to requirements analysis and modeling tasks,especially with UML,has received little attention.This paper investigates the capabilities of generative AI to aid in the creation of three types of UML models:UML use case models,class diagrams,and sequence diagrams.For this purpose,we designed an AI-aided UML modeling task in our course on software requirements modeling.50 undergraduates who majored in Software Engineering at Wuhan University completed the modeling task and the corresponding online survey.Our findings show that generative AI can help create these three types of UML models,but its performance is limited to identifying essential modeling elements of these UML models. 展开更多
关键词 AI-aided education UML modeling Generative AI requirements engineering
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IoT for Streetlighting-Requirements for Modelling of Management Services-Part I
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作者 Mila Ilieva-Obretenova Radi Pipev 《Management Studies》 2023年第5期245-252,共8页
Energy conservation is the effort to reduce the overconsumption of energy by the usage of less energy services.Energy conservation could be user oriented or industry sector oriented.One of these sectors is the streetl... Energy conservation is the effort to reduce the overconsumption of energy by the usage of less energy services.Energy conservation could be user oriented or industry sector oriented.One of these sectors is the streetlighting-major energy consumer in the town-forming nearly 30%of each country’s consumption.Intelligent designed management of streetlighting not only reduces the energy consumption of the town,but also increases the public safety and the wellbeing.The article focuses the management of IoT for streetlighting in smart city.This is the first stage of project“Service management for IoT in streetlighting”.While the basic management principles are efficiency and fairness,the requirements of all actors must be defined.On the base of requirements,the authors synthesize the management functions with selected granularity.The chosen methodology is unified modelling language(UML):use case diagrams.The models are intended to business developers,university professors,and students. 展开更多
关键词 streetlighting IOT requirements management system UML
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An Approach towards Goal-Oriented Requirements Ontology: Consistency and Completeness Based Requirements Analysis
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作者 Mohammad Mustafa Taye Said Ghoul 《Journal of Software Engineering and Applications》 2023年第2期31-49,共19页
The paper presents a new approach to managing software requirement elicitation techniques with a high level of analyses based on domain ontology techniques, where we established a mapping between user scenario, struct... The paper presents a new approach to managing software requirement elicitation techniques with a high level of analyses based on domain ontology techniques, where we established a mapping between user scenario, structured requirement, and domain ontology techniques to improve many attributes such as requirement consistency, completeness and eliminating duplicate requirements to reduce risk of overrun time and budgets. One of the main targets of requirement engineering is to develop a requirement document with high quality. So, we proposed a user interface to collect all vital information about the project directly from the regular user and requirement engineering;After that, the proposal will generate an ontology based on semantic relations and rules. Requirements Engineering tries to keep requirements throughout a project’s life cycle consistent necessities clear, and up to date. This prototype allows mapping requirement scenarios into ontology elements for semantically interrupted. The general points of our prototype are to guarantee the identification requirements and improved nature of the Software Requirements Specification (SRS) by solving incomplete and conflicting information in the requirements specification. 展开更多
关键词 requirements Engineering requirements Elicitation Domain Ontology ONTOLOGY
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On-demand QoS routing protocol based on energy and bandwidth requirement in Ad Hoc networks
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作者 石为人 黄超 雷璐宁 《仪器仪表学报》 EI CAS CSCD 北大核心 2008年第9期1793-1798,共6页
Along with the emergence of real-time multi-media,interactive service,real-time voice and other services calling for high quality of service,there should be a good network to support those services.Most present route ... Along with the emergence of real-time multi-media,interactive service,real-time voice and other services calling for high quality of service,there should be a good network to support those services.Most present route algo- rithms with computational complexity hardly consider the restriction of node energy,so it degrades the whole capabil- ity of network.Bandwidth guarantee is one of the most crucial factors in real-time application,and this paper brings forward a distributed on-demand QoS routing protocol based on energy and bandwidth requirement.This QoS routing protocol makes use of bandwidth calculation algorithm and analyzes its route mechanism.The simulation results veri- fy its validity.The QoS routing protocol improves the packet delivery fraction and average end-to-end delay,prolongs the network lifetime,enhances the network performance and satisfies the route requirement for ad hoc networks. 展开更多
关键词 通信系统 实时多媒体系统 声音 计算方法
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Professional Requirements for Contemporary Teachers
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作者 丁丽红 《海外英语》 2011年第3X期135-136,共2页
The rapid development of high-tech based information technology marks the era of a knowledge-based economy. This form of economy, characterized by knowledge, has raised new demands for most teachers. To rise to the ch... The rapid development of high-tech based information technology marks the era of a knowledge-based economy. This form of economy, characterized by knowledge, has raised new demands for most teachers. To rise to the challenge, teachers must maintain innovative attitudes and practical abilities that will meet the social requirements. The writer examines the professional requirements for contemporary teachers in this paper. 展开更多
关键词 CONTEMPORARY TEACHERS PROFESSIONAL requirements teachers’ CULTURE
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Dietary requirements of synthesizable amino acids by animals:a paradigm shift in protein nutrition 被引量:23
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作者 Guoyao Wu 《Journal of Animal Science and Biotechnology》 SCIE CAS CSCD 2015年第1期1-12,共12页
Amino acids are building blocks for proteins in all animals. Based on growth or nitrogen balance, amino acids were traditionally classified as nutritionally essential or nonessential for mammals, birds and fish. It wa... Amino acids are building blocks for proteins in all animals. Based on growth or nitrogen balance, amino acids were traditionally classified as nutritionally essential or nonessential for mammals, birds and fish. It was assumed that all the "nutritionally nonessential amino acids (NEAA)" were synthesized sufficiently in the body to meet the needs for maximal growth and optimal health. However, careful analysis of the scientific literature reveals that over the past century there has not been compelling experimental evidence to support this assumption. NEAA (e.g., glutamine, glutamate, proline, glycine and arginine) play important roles in regulating gene expression, cell signaling, antioxidative responses, fertility, neurotransmission, and immunity. Additionally, glutamate, glutamine and aspartate are major metabolic fuels for the small intestine to maintain its digestive function and to protect the integrity of the intestinal mucosa. Thus, diets for animals must contain all NEAA to optimize their survival, growth, development, reproduction, and health. Furthermore, NEAA should be taken into consideration in revising the "ideal protein" concept that is currently used to formulate swine and poultry diets. Adequate provision of all amino acids (including NEAA) in diets enhances the efficiency of animal production. In this regard, amino acids should not be classified as nutritionally essential or nonessential in animal or human nutrition. The new Texas A&M University's optimal ratios of dietary amino acids for swine and chickens are expected to beneficially reduce dietary protein content and improve the efficiency of their nutrient utilization, growth, and production performance. 展开更多
关键词 DIET METABOLISM NUTRITION Protein requirements
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Specifying Requirements of Real-Time System with Rules and Templates 被引量:8
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作者 Wu Guo-qing Xiao Hai-feng +1 位作者 Zheng Pen Ying Shi 《Wuhan University Journal of Natural Sciences》 EI CAS 2000年第3期278-284,共7页
This paper presents a model specifying requirements of real-time systems. Different from existing researches, this model mainly uses rules and templates to represent hierarchical FSMs (Finite State Machine). In this m... This paper presents a model specifying requirements of real-time systems. Different from existing researches, this model mainly uses rules and templates to represent hierarchical FSMs (Finite State Machine). In this model, one rule corresponds to one state transition of FSM and one template corresponds to one FSM. Rules and information with respect to a FSM can be written in a template. So templates include not only state diagrams, but also information that can not be described by FSM, such as performance requirements. The specification using this model consists of a collection of templates and it is easy for users to understand and to review. After introduced the related researches and principles of the model, this paper specifies requirements of a real-time system with this model, and discusses characters of this model in the end. 展开更多
关键词 requirements specification model requirements specification real-time system finite state machine
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Dose requirement and complications of diluted and undiluted propofol for deep sedation in endoscopic retrograde cholangiopancreatography 被引量:15
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作者 Somchai Amornyotin Wichit Srikureja +1 位作者 Wiyada Chalayonnavin Siriporn Kongphlay 《Hepatobiliary & Pancreatic Diseases International》 SCIE CAS 2011年第3期313-318,共6页
BACKGROUND:In general,the dose requirement and complications of propofol are lower when used in the diluted form than in the undiluted form.The aim of this study was to determine the dose requirement and complications... BACKGROUND:In general,the dose requirement and complications of propofol are lower when used in the diluted form than in the undiluted form.The aim of this study was to determine the dose requirement and complications of diluted and undiluted propofol for deep sedation in endoscopic retrograde cholangiopancreatography.METHODS:Eighty-six patients were randomly assigned to either group D (diluted propofol) or U (undiluted propofol).All patients were sedated with 0.02-0.03 mg/kg midazolam (total dose ≤2 mg for age <70 years and 1 mg for age ≥70) and 0.5-1 μg/kg fentanyl (total dose ≤75 μg for age <70 and ≤50 μg for age ≥70).Patients in group U (42) were sedated with standard undiluted propofol (10 mg/mL).Patients in group D (44) were sedated with diluted propofol (5 mg/mL).All patients in both groups were monitored for the depth of sedation using the Narcotrend system.The primary outcome variable was the total dose of propofol used during the procedure.The secondary outcome variables were complications during and immediately after the procedure,and recovery time.RESULTS:All endoscopies were completed successfully.Mean propofol doses per body weight and per body weight per hour in groups D and U were 3.0 mg/kg,6.2 mg/kg per hour and 4.7 mg/kg,8.0 mg/kg per hour,respectively.The mean dose of propofol,expressed as total dose,dose/kg or dose/kg per hour and the recovery time were not significantly different between the two groups.Sedation-related adverse events during and immediately after the procedure were higher in group U (42.9%) than in group D (18.2%) (P=0.013).CONCLUSIONS:Propofol requirement and recovery time in the diluted and undiluted propofol groups were comparable.However,the sedation-related hypotension was significantly lower in the diluted group than the undiluted group. 展开更多
关键词 PROPOFOL dose requirement COMPLICATION endoscopic retrograde cholangiopancreatography
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Practical starter pig amino acid requirements in relation to immunity,gut health and growth performance 被引量:8
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作者 Bob Goodband Mike Tokach +2 位作者 Steve Dritz Joel DeRouchey Jason Woodworth 《Journal of Animal Science and Biotechnology》 SCIE CAS 2014年第3期251-261,共11页
Immune system activation begins a host of physiological responses. Infectious agents are recognized by monocytes and macrophages which in turn stimulate cytokine production. It is the hormone-like factors called cytok... Immune system activation begins a host of physiological responses. Infectious agents are recognized by monocytes and macrophages which in turn stimulate cytokine production. It is the hormone-like factors called cytokines that orchestrate the immune response. The classic responses observed with immune system activation and cytokine production include: anorexia, fever, lethargy, recruitment of other immune cells, and phagocytosis. While production of immune system components is known to require some amino acids, increases in amino acid requirements are more than offset by the associated decrease in protein accretion and increased muscle protein degradation that also accompanies immune system activation. However, the biggest impact of cytokine production is a decrease in feed intake. Therefore, as feed intake decreases, the energy needed to drive protein synthesis is also decreased. This suggests that diets should still be formulated on a similar calorie:lysine ratio as those formulated for non-immune challenged pigs. The evidence is sparse or equivocal for increasing nutrient requirements during an immune challenge. Nutritionists and swine producers should resist the pressure to alter the diet, limit feed, or add expensive feed additives during an immune challenge. While immune stimulation does not necessitate changes in diet formulation, when pigs are challenged with non-pathogenic diarrhea there are potential advantages on gut health with the increased use of crystalline amino acids rather than intact protein sources (i.e., soybean meal). This is because reducing crude protein decreases the quantity of fermentable protein entering the large intestine, which lowers post weaning diarrhea. It also lowers the requirement for expensive specialty protein sources or other protein sources such as soybean meal that present immunological challenges to the gut. The objective of this review is two-fold. The first is to discuss immunity by nutrition interactions, or lack thereof, and secondly, to review amino acid requirement estimates for nursery pigs. 展开更多
关键词 Amino acids IMMUNITY PIGS requirements
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