A new coordination polymer,[Co2(L)2(H2O)2]n·H2O(1,H2L?=?5-(1H-1,2,4-triazol-1-yl)-1,3-benzenedicarboxylic acid),was constructed by hydrothermal condition reaction of Co(NO3)2·6H2O and H2L at the pH value of ...A new coordination polymer,[Co2(L)2(H2O)2]n·H2O(1,H2L?=?5-(1H-1,2,4-triazol-1-yl)-1,3-benzenedicarboxylic acid),was constructed by hydrothermal condition reaction of Co(NO3)2·6H2O and H2L at the pH value of 5.6.The as-prepared complex 1 was characterized by elemental analysis,IR and single-crystal X-ray diffraction.Furthermore,a green hand grinding technique has been implemented to reduce the particle size of complex 1 to generate nanoscale 1(denoted as nano 1 hereafter)with spherical morphology.Furthermore,the treatment of the compound on anxiety and insomnia was evaluated.Firstly,the ELISA was used to detect the content of serotonin,gamma-aminobutyric acid in the brain.Besides,the Rat sleep phase detection was determined by pentobarbital synergistic sleep experiment.展开更多
文摘A new coordination polymer,[Co2(L)2(H2O)2]n·H2O(1,H2L?=?5-(1H-1,2,4-triazol-1-yl)-1,3-benzenedicarboxylic acid),was constructed by hydrothermal condition reaction of Co(NO3)2·6H2O and H2L at the pH value of 5.6.The as-prepared complex 1 was characterized by elemental analysis,IR and single-crystal X-ray diffraction.Furthermore,a green hand grinding technique has been implemented to reduce the particle size of complex 1 to generate nanoscale 1(denoted as nano 1 hereafter)with spherical morphology.Furthermore,the treatment of the compound on anxiety and insomnia was evaluated.Firstly,the ELISA was used to detect the content of serotonin,gamma-aminobutyric acid in the brain.Besides,the Rat sleep phase detection was determined by pentobarbital synergistic sleep experiment.
