Extensive improvements in small-scale thermal systems in electronic circuits,automotive industries,and microcomputers conduct the study of microsystems as essential.Flow and thermic field characteristics of the cohere...Extensive improvements in small-scale thermal systems in electronic circuits,automotive industries,and microcomputers conduct the study of microsystems as essential.Flow and thermic field characteristics of the coherent nanofluid-guided microchannel heat sink are described in this perusal.The porous media approximate was used to search the heat distribution in the expanded sheet and Cu:γ-AlOOH/water.A hybrid blend of Boehme copper and aluminum nanoparticles is evaluated to have a cooling effect on the microchannel heat sink.By using Akbari Ganji and finite element methods,linear and non-linear differential equations as well as simple dimensionless equations have been analyzed.The purpose of this study is to investigate the fluid and thermal parameters of copper hybrid solution added to water,such as Nusselt number and Darcy number so that we can reach the best cooling of the fluid.Also,by installing a piece of fin on the wall of the heat sink,the coefficient of conductive heat transfer and displacement heat transfer with the surrounding air fluid increases,and the efficiency of the system increases.The overall results show that expanding values on the NP(series heat transfer fluid system maximizes performance with temperatures)volume division of copper,as well as boehmite alumina particles,lead to a decrease within the stream velocity of the Cu:AlOOH/water.Increasing the volume fraction of nanoparticles in the hybrid mixture decreases the temperature of the solid surface and the hybrid nanofluid.The Brownian movement improves as the volume percentage of nanoparticles in the hybrid mixture grows,spreading the heat across the environment.As a result,heat transmission rates rise.As the Darcy number increases,the thermal field for solid sections and Cu:AlOOH/water improves.展开更多
为了探讨小鼠胚胎主动脉-性腺-中肾(aorta-gonad-mesonephros,AGM)区基质微环境对胚胎造血的作用,分离鉴定小鼠背主动脉(dorsalaorta,DA)来源间充质干细胞样基质细胞(mesenchymal stem cell like stromal cells,MSC like stromal cells...为了探讨小鼠胚胎主动脉-性腺-中肾(aorta-gonad-mesonephros,AGM)区基质微环境对胚胎造血的作用,分离鉴定小鼠背主动脉(dorsalaorta,DA)来源间充质干细胞样基质细胞(mesenchymal stem cell like stromal cells,MSC like stromal cells)并研究其生长特性、表面标志和间质分化能力。取E11.5小鼠胚胎,分离获得DA区细胞,转染质粒pSV3neo-SV40,筛选具有G418抗性的阳性细胞,挑取成纤维样细胞,传代培养并检测其增殖能力,应用流式细胞术检测相关表面标志,诱导其向脂肪、成骨和成软骨细胞分化。结果表明:筛选获得的20个细胞克隆多为成纤维样细胞。mDAF3和mDAF18可在体外传代50代以上,稳定表达G418抗性,细胞倍增时间约为24小时,具有向成骨细胞、脂肪细胞和成软骨细胞分化的能力,流式细胞术检测结果显示其表达CD29、CD44、CD105、Sca-1,弱表达CD34,CD45和CD31。结论:永生化的mDAF3和mDAF18具有MSC的表型特征和分化功能,提示小鼠胚胎DA区可能存在MSC,小鼠胚胎DA区MSC样基质细胞可为研究基质微环境对胚胎造血发育的调控作用提供支持细胞。展开更多
文摘Extensive improvements in small-scale thermal systems in electronic circuits,automotive industries,and microcomputers conduct the study of microsystems as essential.Flow and thermic field characteristics of the coherent nanofluid-guided microchannel heat sink are described in this perusal.The porous media approximate was used to search the heat distribution in the expanded sheet and Cu:γ-AlOOH/water.A hybrid blend of Boehme copper and aluminum nanoparticles is evaluated to have a cooling effect on the microchannel heat sink.By using Akbari Ganji and finite element methods,linear and non-linear differential equations as well as simple dimensionless equations have been analyzed.The purpose of this study is to investigate the fluid and thermal parameters of copper hybrid solution added to water,such as Nusselt number and Darcy number so that we can reach the best cooling of the fluid.Also,by installing a piece of fin on the wall of the heat sink,the coefficient of conductive heat transfer and displacement heat transfer with the surrounding air fluid increases,and the efficiency of the system increases.The overall results show that expanding values on the NP(series heat transfer fluid system maximizes performance with temperatures)volume division of copper,as well as boehmite alumina particles,lead to a decrease within the stream velocity of the Cu:AlOOH/water.Increasing the volume fraction of nanoparticles in the hybrid mixture decreases the temperature of the solid surface and the hybrid nanofluid.The Brownian movement improves as the volume percentage of nanoparticles in the hybrid mixture grows,spreading the heat across the environment.As a result,heat transmission rates rise.As the Darcy number increases,the thermal field for solid sections and Cu:AlOOH/water improves.
文摘为了探讨小鼠胚胎主动脉-性腺-中肾(aorta-gonad-mesonephros,AGM)区基质微环境对胚胎造血的作用,分离鉴定小鼠背主动脉(dorsalaorta,DA)来源间充质干细胞样基质细胞(mesenchymal stem cell like stromal cells,MSC like stromal cells)并研究其生长特性、表面标志和间质分化能力。取E11.5小鼠胚胎,分离获得DA区细胞,转染质粒pSV3neo-SV40,筛选具有G418抗性的阳性细胞,挑取成纤维样细胞,传代培养并检测其增殖能力,应用流式细胞术检测相关表面标志,诱导其向脂肪、成骨和成软骨细胞分化。结果表明:筛选获得的20个细胞克隆多为成纤维样细胞。mDAF3和mDAF18可在体外传代50代以上,稳定表达G418抗性,细胞倍增时间约为24小时,具有向成骨细胞、脂肪细胞和成软骨细胞分化的能力,流式细胞术检测结果显示其表达CD29、CD44、CD105、Sca-1,弱表达CD34,CD45和CD31。结论:永生化的mDAF3和mDAF18具有MSC的表型特征和分化功能,提示小鼠胚胎DA区可能存在MSC,小鼠胚胎DA区MSC样基质细胞可为研究基质微环境对胚胎造血发育的调控作用提供支持细胞。
