Autophagy,which means‘‘self-eating’’,is a process in which a portion of the cytosol is enclosed in a double-membrane autophagosome and delivered to the hydrolytic vacuole/lysosome for recycling(Fig.1).Bulk degrada...Autophagy,which means‘‘self-eating’’,is a process in which a portion of the cytosol is enclosed in a double-membrane autophagosome and delivered to the hydrolytic vacuole/lysosome for recycling(Fig.1).Bulk degradation by autophagy provides energy and materials for cell survival under various stress conditions such as starvation and energy deprivation.Autophagy also has a scavenging function展开更多
基金supported by grants from the National Basic Research Program of China (2013CB910100)the National Science Foundation of China (31421002, 31561143001, 31225018)also by an International Early Career Scientist Grant from the Howard Hughes Medical Institute
文摘Autophagy,which means‘‘self-eating’’,is a process in which a portion of the cytosol is enclosed in a double-membrane autophagosome and delivered to the hydrolytic vacuole/lysosome for recycling(Fig.1).Bulk degradation by autophagy provides energy and materials for cell survival under various stress conditions such as starvation and energy deprivation.Autophagy also has a scavenging function
