行为分析训练法结合醒神益智针刺疗法促进儿童孤独症康复效果观察

目的观察行为分析训练法(ABA)结合醒神益智针刺疗法促进儿童孤独症康复效果。方法研究纳入共计86例儿童孤独症(2021年3月—2022年11月收治)进行研究,采取随机数字表法将患儿分为观察组(43例)与对照组(43例),对照组患儿采取ABA训练法治疗,观察组患儿在ABA训练法治疗基础上结合醒神益智针刺疗法治疗,各组数据观察:治疗效果、治疗前后患儿中医证候积分(语言迟钝、精神呆滞、智力低下、纳食欠佳等)变化、治疗后运动能力改善时间与语言表达能力好转时间、治疗前后患儿孤独症治疗评估表(Autism Treatment Evaluation Checklist,ATEC)评分变化及儿童孤独症评定量表(Childhood autism rating scale,CARS)评分变化、孤独症行为量表(Autism Behavior Checklist,ABC)评分变化、患儿治疗前后发育商(Developmental quotient,DQ)及社会生活能力量表(Social life ability scale,SM)评分变化、治疗前后血清纤溶酶原激活物抑制因子-1(Plasminogen activator inhibitor-1,PAI-1)及组织型纤溶酶原激活剂(Tissue Plasmin activator,t-PA)水平变化。结果观察组患儿治疗总有效率(93.02%)高于对照组(76.74%),P<0.05;观察组患儿运动能力改善时间与语言表达能力好转时间均比对照组患儿短,P<0.05;治疗前各组患儿中医证候积分(语言迟钝、精神呆滞、智力低下、纳食欠佳等)、ATEC评分及CARS评分、ABC评分及DQ评分、SM评分、PAI-1及t-PA水平比较,P>0.05,治疗后各组患儿中医证候积分(语言迟钝、精神呆滞、智力低下、纳食欠佳等)、ATEC评分及CARS评分、ABC评分及DQ评分、SM评分、PAI-1及t-PA水平均改善,观察组患儿治疗后中医证候积分(语言迟钝、精神呆滞、智力低下、纳食欠佳等)、ATEC评分及CARS评分、ABC评分及DQ评分、SM评分、PAI-1及t-PA水平均优于对照组患儿,P<0.05。结论ABA训练法结合醒神益智针刺疗法可较好促进儿童孤独症康复,患儿治疗效果佳,症状改善,发育好,值得应用。

基于ABA法的听觉统合训练对自闭症谱系障碍患儿社交能力及语言发育水平的影响

目的探讨基于行为分析(ABA)法的听觉统合训练对自闭症谱系障碍(ASD)患儿社交能力及语言发育水平的影响。方法选取2018年7月~2019年7月我科收治的87例ASD患儿作为研究对象,根据随机数字表法分为对照组和观察组。对照组43例给予常规训练。观察组44例给予基于ABA法的听觉统合训练。比较两组训练前、训练6个月后孤独症行为量表(ABC)评分、儿童孤独症评定量表(CARS)评分、自闭症儿童心理教育评核第三版(PEP-3)评分;自闭症治疗评估表(ATEC)评分及语言发育水平。结果观察组训练后ABC、CARS、ATEC评分低于对照组,PEP-3评分高于对照组,语言发育水平优于对照组(P<0.05)。结论基于ABA法的听觉统合训练可提高ASD患儿的认知行为能力,改善心理障碍,提高语言能力和社交能力。

Studies on the Dynamics of Endogenous GAs, ABA and IAA in the Shoot Apex of Chinese Pine in Relation to Male Cone Bud Initiation

The endogenous GAs, ABA and IAA in the shoot apices of 8-year-old Chinese pines, flowered, non-flowered and non-flowered but treated with GA4/7 were analyzed by GC-MS-SIM.The results demonstrated that GA3 and GA9 levels were obviously higher in flowered plants than in non-flowered. A peak value of GA3 in flowered plants occurred after appearance of the earliest auxiliary bud primorda which had the possibility of transforming into male cone bud primordia and before the morphological initiation of male cone bud primordia. Exogenously applied GA4/7 could enhance the endogenous GA3 and GA9, this may benefit the promotion of male cone buds in Chinese pine. The relations among ex-ogenously applied GA4/7 endogenous GAs, ABA and IAA in the shoot apices, and the initiation of male cone bud are discussed.