Two new coordination polymers, [Cd（N3）2（Baep）l/2]n （1） and [Cd2（N3）4（CH3OH）（Bapp）I/.2]n （2） （Baep = 1,4-bis（2-aminoethyl）piperazine, Bapp = 1,4-bis（3-aminopropyl）piperazine） were synthesized. The c...Two new coordination polymers, [Cd（N3）2（Baep）l/2]n （1） and [Cd2（N3）4（CH3OH）（Bapp）I/.2]n （2） （Baep = 1,4-bis（2-aminoethyl）piperazine, Bapp = 1,4-bis（3-aminopropyl）piperazine） were synthesized. The crystal of 1 is of monoclinic system, space group P21/c with a = 9.341（7）, b = 11.677（9）, c = 8.195（6） A, fl = 93.925（13）, V= 891.8（11） A3, Z= 4, μ（MoKa） = 2.42 mm-1, Mr = 280.58, Dc = 2.090 g/cm3, the final R = 0.0297 and wR = 0.0720. The crystal of 2 is of triclinic system, space group PI with a = 9.121（5）, b = 9.666（5）, c = 10.250（6） A, a = 72.91（2）, β= 77.10（2）, V = 73.95（2）°, V = 820.0（8）°, Z = 2,μ（MoKa） = 2.62 mm-1, Mr= 522.10, Dc = 2.114 g/cm3, the final R = 0.0251 and wR = 0.0632. Single-crystal X-ray diffraction studies reveal that 1 is a 3D structure based on a dinuclear unit {Cd2（N3）a（Baep）}, in which the Baep ligands formed in situ display two different bridging modes. Compound 2 also has a 3D structure based on a tetranuclear cluster {Cda（N3）8（CH3OH）2（Bapp）}, in which the azido anions exhibit four different bridging modes （μ-1,1, μ-1,3, μ-l,l,1 and μ-1,1,3）. The thermal stability and fluorescent property of 1 and 2 have also been investigated.展开更多
A series of fluorine- and piperazine-containing 1,2,4-triazole thione derivatives were synthesized by the Mannich reaction of triazole intermediates with various substituted piperazines and formaldehyde in high yields...A series of fluorine- and piperazine-containing 1,2,4-triazole thione derivatives were synthesized by the Mannich reaction of triazole intermediates with various substituted piperazines and formaldehyde in high yields. Structures of title compounds were confirmed by melting points, IR,~1H NMR,^（13）C NMR and elemental analysis. The preliminary bioassays for 17 novel title compounds showed that several compounds have significant fungicidal activity against Cercospora arachidicola, Physalospora piricola and Rhizoctonia cerealis at 50 mg/m L.展开更多
We designed and synthesized 5 new compounds. Their chemical structures were confirmed by means of MS, HNMR andelemental analysis. FPA was tested for positive inotropic activity. The results showed that FPA could incre...We designed and synthesized 5 new compounds. Their chemical structures were confirmed by means of MS, HNMR andelemental analysis. FPA was tested for positive inotropic activity. The results showed that FPA could increase the contrastive amplitudeof isolated atrium of guinea pigs and had no influence upon rhythm of the hearts.展开更多
以D-氨基葡萄糖盐酸盐为起始原料,经过羟基的乙酰化保护,得到2-氨基-1,3,4,6-四-O-乙酰基-2-脱氧-β-D-吡喃糖盐酸盐;然后在三乙胺存在下,与三光气、哌嗪衍生物"一锅法"反应,合成4种具有代表性的糖基哌嗪物质.产物结构均经FT-...以D-氨基葡萄糖盐酸盐为起始原料,经过羟基的乙酰化保护,得到2-氨基-1,3,4,6-四-O-乙酰基-2-脱氧-β-D-吡喃糖盐酸盐;然后在三乙胺存在下,与三光气、哌嗪衍生物"一锅法"反应,合成4种具有代表性的糖基哌嗪物质.产物结构均经FT-IR,1 H NMR和HRMS(ESI)确认.展开更多
选用六水合哌嗪为母体,二氯甲烷为溶剂,三乙胺为缚酸剂,正己胺、十二胺、氯乙酰氯为原料,合成新型可生物降解润滑油添加剂1,4-双(二硫代甲酸乙酰正己胺)哌嗪和1,4-双(二硫代甲酸乙酰十二胺)哌嗪;采用FT-IR,1 H NMR,TG手段对合成产物进...选用六水合哌嗪为母体,二氯甲烷为溶剂,三乙胺为缚酸剂,正己胺、十二胺、氯乙酰氯为原料,合成新型可生物降解润滑油添加剂1,4-双(二硫代甲酸乙酰正己胺)哌嗪和1,4-双(二硫代甲酸乙酰十二胺)哌嗪;采用FT-IR,1 H NMR,TG手段对合成产物进行结构表征及对产品热稳定性进行测试。以菜籽油为基础油,采用四球摩擦磨损试验机考察合成添加剂的抗磨性能,并对其进行可生物降解性测定。结果表明:合成产品与预测结构相同,热分解温度最低为305℃,与菜籽油的溶解度(质量分数)高达2.58%,1,4-双(二硫代甲酸乙酰十二胺)哌嗪具有较好的抗磨性能,1,4-双(二硫代甲酸乙酰正己胺)哌嗪具有较好的减摩性能,两者均具有优异的可生物降解性能(BDI大于80%)。展开更多
基金supported by the National Basic Research Program of China(973Program,2012CB821702)the National Natural Science Foundation of China(21173221and20903096)+1 种基金the State Key Laboratory of Structural ChemistryFujian Institute of Research onthe Structure of Matter,Chinese Academy of Sciences,Fuzhou,Fujian350002,China
文摘Two new coordination polymers, [Cd（N3）2（Baep）l/2]n （1） and [Cd2（N3）4（CH3OH）（Bapp）I/.2]n （2） （Baep = 1,4-bis（2-aminoethyl）piperazine, Bapp = 1,4-bis（3-aminopropyl）piperazine） were synthesized. The crystal of 1 is of monoclinic system, space group P21/c with a = 9.341（7）, b = 11.677（9）, c = 8.195（6） A, fl = 93.925（13）, V= 891.8（11） A3, Z= 4, μ（MoKa） = 2.42 mm-1, Mr = 280.58, Dc = 2.090 g/cm3, the final R = 0.0297 and wR = 0.0720. The crystal of 2 is of triclinic system, space group PI with a = 9.121（5）, b = 9.666（5）, c = 10.250（6） A, a = 72.91（2）, β= 77.10（2）, V = 73.95（2）°, V = 820.0（8）°, Z = 2,μ（MoKa） = 2.62 mm-1, Mr= 522.10, Dc = 2.114 g/cm3, the final R = 0.0251 and wR = 0.0632. Single-crystal X-ray diffraction studies reveal that 1 is a 3D structure based on a dinuclear unit {Cd2（N3）a（Baep）}, in which the Baep ligands formed in situ display two different bridging modes. Compound 2 also has a 3D structure based on a tetranuclear cluster {Cda（N3）8（CH3OH）2（Bapp）}, in which the azido anions exhibit four different bridging modes （μ-1,1, μ-1,3, μ-l,l,1 and μ-1,1,3）. The thermal stability and fluorescent property of 1 and 2 have also been investigated.
基金supported by the National Natural Science Foundation of China (No. 21372133)‘‘111’’ Project of Ministry of Education of China (No. B06005)
文摘A series of fluorine- and piperazine-containing 1,2,4-triazole thione derivatives were synthesized by the Mannich reaction of triazole intermediates with various substituted piperazines and formaldehyde in high yields. Structures of title compounds were confirmed by melting points, IR,~1H NMR,^（13）C NMR and elemental analysis. The preliminary bioassays for 17 novel title compounds showed that several compounds have significant fungicidal activity against Cercospora arachidicola, Physalospora piricola and Rhizoctonia cerealis at 50 mg/m L.
文摘We designed and synthesized 5 new compounds. Their chemical structures were confirmed by means of MS, HNMR andelemental analysis. FPA was tested for positive inotropic activity. The results showed that FPA could increase the contrastive amplitudeof isolated atrium of guinea pigs and had no influence upon rhythm of the hearts.
基金The project supported by National Natural Science Foundation of China(81070196)Natural Science Foundation of Beijing(7082101)Program for New Century Excellent Talents in University and Beijing Talents Foundation(BMU20100012)~~
文摘选用六水合哌嗪为母体,二氯甲烷为溶剂,三乙胺为缚酸剂,正己胺、十二胺、氯乙酰氯为原料,合成新型可生物降解润滑油添加剂1,4-双(二硫代甲酸乙酰正己胺)哌嗪和1,4-双(二硫代甲酸乙酰十二胺)哌嗪;采用FT-IR,1 H NMR,TG手段对合成产物进行结构表征及对产品热稳定性进行测试。以菜籽油为基础油,采用四球摩擦磨损试验机考察合成添加剂的抗磨性能,并对其进行可生物降解性测定。结果表明:合成产品与预测结构相同,热分解温度最低为305℃,与菜籽油的溶解度(质量分数)高达2.58%,1,4-双(二硫代甲酸乙酰十二胺)哌嗪具有较好的抗磨性能,1,4-双(二硫代甲酸乙酰正己胺)哌嗪具有较好的减摩性能,两者均具有优异的可生物降解性能(BDI大于80%)。
