Thread lifting is one of the widely chosen procedures for minimally invasive facial rejuvenation. Traditional facial thread lifting has nearly inevitable side effects e.g. facial edema, facial bruising, prolonged reco...Thread lifting is one of the widely chosen procedures for minimally invasive facial rejuvenation. Traditional facial thread lifting has nearly inevitable side effects e.g. facial edema, facial bruising, prolonged recovery, skin puckering, and visible and/or palpable threads, as well as less common complications e.g. damage of facial vital structures. Applying the extrafacial loose areolar (XFLA) thread lifting technique by using loose areolar connective tissue, the fourth layer of the scalp, as insertion medium for the threads to be anchored to the layer above (epicranial aponeurosis or galea aponeurotica) and the layer below (pericranium), could help minimize most of the previously mentioned side effects. In this manuscript, technique steps will be detailed to prove its novelty.展开更多
Background A Chinese family with autosomal dominant central areolar choroidal dystrophy （CACD） was identified. The purpose of this study was to collect the clinical findings from the family and to identify the genet...Background A Chinese family with autosomal dominant central areolar choroidal dystrophy （CACD） was identified. The purpose of this study was to collect the clinical findings from the family and to identify the genetic entity by linkage analysis.Methods Forty-three individuals from 3 generations of the family underwent ophthalmologic examinations, including best-corrected visual acuity, examination of the anterior segments, and inspection of the ocular fundus after pharmacologic mydriasis. Affected family members further underwent color vision test, color fundus photography, fluorescein angiography, automated perimetry, and electroretinography. The family was followed up for 30 months. Peripheral venous blood or buccal swabs were collected from each family member and genomic DNA was extracted. Linkage analysis was performed for candidate genes or loci using microsatellite markers.Results Seven family members in 3 continuous generations were diagnosed as having autosomal dominant CACD. The family showed progressive development of the disease, affecting both male and female. Age of onset of visual disturbances varied between 11 and 50 years. Phenotypic variability among affected individuals was apparent and ranged from relatively normal-appearing fundus with mild parafoveal pigment mottling to geographic atrophy of the macula. Fluorescein angiography showed hyperfluorescent parafoveal changes in early stage or well-demarcated area of chorioretinal atrophy with enhanced visibility of the residual underlying choroidal vessels in the late stage. Peripheral retina and visual fields were normal in affected individuals. Electroretinogram showed normal or mild reduction in the photopic amplitude. Eight candidate genes （STGD4, RCD1, peripherin/RDS, GUCA 1A, RIMS1, UNC119, GUCY2D, and AIPL1） and two genetic loci （4p15.2-16.3, and 17p13） were excluded to be responsible for the disease by linkage analysis.Conclusions The clinical findings Of this Chinese family with CACD shared similarities with previously reported families of other ethnicities. Linkage analysis excluded the known genes and genetic loci, indicating genetic heterogeneity of the disease.展开更多
Objective To investigate the use of vertical intra-areolar incision in dual plane breast augmentation.Methods Fifteen cases received dual plane breast augmentation with vertical intra-areola incision in our hospital f...Objective To investigate the use of vertical intra-areolar incision in dual plane breast augmentation.Methods Fifteen cases received dual plane breast augmentation with vertical intra-areola incision in our hospital from January 2008 to December 2008.Breast gland was cut vertically in the upper part and pectoralis major muscle was separated according to the direction of the muscle fiber.Then the pectoralis major muscle was partially amputated at the starting point.Finally the implant was placed partially under the breast gland and partially under the pectoralis major muscle.Results The follow-up of more than one year showed all cases healed well and the incisions were concealed except one case who suffered delayed healing of the wound and depigmentation of the incision.Conclusion Vertical intra-areolar incision in dual plane breast augmentation is an easily-performed and feasible method and leaves less scar post operation.展开更多
文摘Thread lifting is one of the widely chosen procedures for minimally invasive facial rejuvenation. Traditional facial thread lifting has nearly inevitable side effects e.g. facial edema, facial bruising, prolonged recovery, skin puckering, and visible and/or palpable threads, as well as less common complications e.g. damage of facial vital structures. Applying the extrafacial loose areolar (XFLA) thread lifting technique by using loose areolar connective tissue, the fourth layer of the scalp, as insertion medium for the threads to be anchored to the layer above (epicranial aponeurosis or galea aponeurotica) and the layer below (pericranium), could help minimize most of the previously mentioned side effects. In this manuscript, technique steps will be detailed to prove its novelty.
基金This work was supported by grants from Beijing Natural Science Foundation （No. 7072020） and National Natural Science Foundation of China （No. 30772378）.
文摘Background A Chinese family with autosomal dominant central areolar choroidal dystrophy （CACD） was identified. The purpose of this study was to collect the clinical findings from the family and to identify the genetic entity by linkage analysis.Methods Forty-three individuals from 3 generations of the family underwent ophthalmologic examinations, including best-corrected visual acuity, examination of the anterior segments, and inspection of the ocular fundus after pharmacologic mydriasis. Affected family members further underwent color vision test, color fundus photography, fluorescein angiography, automated perimetry, and electroretinography. The family was followed up for 30 months. Peripheral venous blood or buccal swabs were collected from each family member and genomic DNA was extracted. Linkage analysis was performed for candidate genes or loci using microsatellite markers.Results Seven family members in 3 continuous generations were diagnosed as having autosomal dominant CACD. The family showed progressive development of the disease, affecting both male and female. Age of onset of visual disturbances varied between 11 and 50 years. Phenotypic variability among affected individuals was apparent and ranged from relatively normal-appearing fundus with mild parafoveal pigment mottling to geographic atrophy of the macula. Fluorescein angiography showed hyperfluorescent parafoveal changes in early stage or well-demarcated area of chorioretinal atrophy with enhanced visibility of the residual underlying choroidal vessels in the late stage. Peripheral retina and visual fields were normal in affected individuals. Electroretinogram showed normal or mild reduction in the photopic amplitude. Eight candidate genes （STGD4, RCD1, peripherin/RDS, GUCA 1A, RIMS1, UNC119, GUCY2D, and AIPL1） and two genetic loci （4p15.2-16.3, and 17p13） were excluded to be responsible for the disease by linkage analysis.Conclusions The clinical findings Of this Chinese family with CACD shared similarities with previously reported families of other ethnicities. Linkage analysis excluded the known genes and genetic loci, indicating genetic heterogeneity of the disease.
文摘Objective To investigate the use of vertical intra-areolar incision in dual plane breast augmentation.Methods Fifteen cases received dual plane breast augmentation with vertical intra-areola incision in our hospital from January 2008 to December 2008.Breast gland was cut vertically in the upper part and pectoralis major muscle was separated according to the direction of the muscle fiber.Then the pectoralis major muscle was partially amputated at the starting point.Finally the implant was placed partially under the breast gland and partially under the pectoralis major muscle.Results The follow-up of more than one year showed all cases healed well and the incisions were concealed except one case who suffered delayed healing of the wound and depigmentation of the incision.Conclusion Vertical intra-areolar incision in dual plane breast augmentation is an easily-performed and feasible method and leaves less scar post operation.
