Aromatic amino acid halides are valuable amino acid derivatives and fundamental building blocks that are used to various coupling reaction^1-3!,such as Heck,Suzuki and Ullmann reaction[4-7],and also important precurso...Aromatic amino acid halides are valuable amino acid derivatives and fundamental building blocks that are used to various coupling reaction^1-3!,such as Heck,Suzuki and Ullmann reaction[4-7],and also important precursors of active natural products,pharmaceuticals and chiral auxiliaries[8-9].展开更多
A library of novel 3-aryl isoindolinone derivatives with aromatic amino acid derivative fragments was designed and synthesized. Two synthetic routes were employed to construct 3-aryl isoindolinone ring system for diff...A library of novel 3-aryl isoindolinone derivatives with aromatic amino acid derivative fragments was designed and synthesized. Two synthetic routes were employed to construct 3-aryl isoindolinone ring system for different amino acid derivatives.展开更多
基金supported by the National Key R&D Program of China(No.2019YFE0119300)the National Natural Science Foundation of China(Nos.32088101,91853101)+3 种基金the Grant from Chinese Academy of Sciences(No.ZDBSLY-SLH032)the Natural Science Foundation of Liaoning Province,China(No.2019-YQ-07)the Dalian Science and Technology Innovation Foundation,China (No.2019J11CY019)the Grant from Dalian Institute of Chemical Physics,CAS(No.DICP I202007).
文摘Aromatic amino acid halides are valuable amino acid derivatives and fundamental building blocks that are used to various coupling reaction^1-3!,such as Heck,Suzuki and Ullmann reaction[4-7],and also important precursors of active natural products,pharmaceuticals and chiral auxiliaries[8-9].
基金Supported by the National Natural Science Foundation of China（No.81072526） and the Fund of the Department of Science and Technology of Jilin Province of China（No.20106039）.
文摘A library of novel 3-aryl isoindolinone derivatives with aromatic amino acid derivative fragments was designed and synthesized. Two synthetic routes were employed to construct 3-aryl isoindolinone ring system for different amino acid derivatives.
