Novel chiral multidentate P_3N_4-type ligand has been synthesized and characterized by NMR and HRMS.Using i-PrOH as solvent and hydrogen source, asymmetric transfer hydrogenation of various ketones was investigated. T...Novel chiral multidentate P_3N_4-type ligand has been synthesized and characterized by NMR and HRMS.Using i-PrOH as solvent and hydrogen source, asymmetric transfer hydrogenation of various ketones was investigated. The catalyst generated in situ from chiral multidentate aminophosphine ligand(R,R,R,R)-3 and IrCl(CO)(PPh_3)_2exhibited highly catalytic activity and excellent enantioselectivity under mild conditions, achieving the corresponding chiral alcohols with up to 99% yield and 99% ee.展开更多
The asymmetric borane reduction of carbonyl compounds using chiral catalysts is one of the most active research. Among them,Oxazaborolidines developed by Corey are most significant- Herein. we report the use of sufony...The asymmetric borane reduction of carbonyl compounds using chiral catalysts is one of the most active research. Among them,Oxazaborolidines developed by Corey are most significant- Herein. we report the use of sufonylamides as chiral catalysts to reduce aromatic ketone in high yield and with e.e. of up to 91 %. Scheme:展开更多
A quantitative interpretation of mass spectra of complex organic compounds so far is notvery perfect and needs some further investigation. In this paper a mechanism of cleft-rate-determining-steps of aromatic conjugat...A quantitative interpretation of mass spectra of complex organic compounds so far is notvery perfect and needs some further investigation. In this paper a mechanism of cleft-rate-determining-steps of aromatic conjugated polyenic acid, methyl benzoate, methyl phenyl ketone,benzonitrile and aniline is proposed, and various quantum parameters of molecular ions ofaromatic conjugated polyenic compounds, together with their framents are calculated bymeans of CNDO/2 method. Through the process of calculation, the peak-height of mass spectracan be quantitatively interpreted, which means that the main factors which influence the cleftforms of simple cleavage of mass spectra of conjugated compounds given by the authorsmight be true to some extent.展开更多
基金the National Natural Science Foundation of China (No. 21173176)the Program for Innovative Research Team in Chinese Universities (No. IRT_14R31)+1 种基金the Fundamental Research Funds for the Central Universities (No. 20720150040)NFFTBS (No. J1310024) for financial support
文摘Novel chiral multidentate P_3N_4-type ligand has been synthesized and characterized by NMR and HRMS.Using i-PrOH as solvent and hydrogen source, asymmetric transfer hydrogenation of various ketones was investigated. The catalyst generated in situ from chiral multidentate aminophosphine ligand(R,R,R,R)-3 and IrCl(CO)(PPh_3)_2exhibited highly catalytic activity and excellent enantioselectivity under mild conditions, achieving the corresponding chiral alcohols with up to 99% yield and 99% ee.
文摘The asymmetric borane reduction of carbonyl compounds using chiral catalysts is one of the most active research. Among them,Oxazaborolidines developed by Corey are most significant- Herein. we report the use of sufonylamides as chiral catalysts to reduce aromatic ketone in high yield and with e.e. of up to 91 %. Scheme:
文摘A quantitative interpretation of mass spectra of complex organic compounds so far is notvery perfect and needs some further investigation. In this paper a mechanism of cleft-rate-determining-steps of aromatic conjugated polyenic acid, methyl benzoate, methyl phenyl ketone,benzonitrile and aniline is proposed, and various quantum parameters of molecular ions ofaromatic conjugated polyenic compounds, together with their framents are calculated bymeans of CNDO/2 method. Through the process of calculation, the peak-height of mass spectracan be quantitatively interpreted, which means that the main factors which influence the cleftforms of simple cleavage of mass spectra of conjugated compounds given by the authorsmight be true to some extent.
