The aim of this paper was to prepare an artificial bile duct using polytetrafluoroethylene（PTFE） for the development of a new treatment for biliary diseases. The basic properties of the PTFE material, such as crysta...The aim of this paper was to prepare an artificial bile duct using polytetrafluoroethylene（PTFE） for the development of a new treatment for biliary diseases. The basic properties of the PTFE material, such as crystallization properties, were characterized; the surface structures of the sample tubes were observed by scanning electron microscope（SEM） and water permeability test of different tubes was evaluated by osmosis device. Six Shanghai white pigs were selected to do the implantation surgery of the artificial biIe ducts. After 90 days, the artifidai bile ducts were removed from the pigs and characterized by electron microscope in order to study the tissue compatibility. The results of animal test indicated that the artificial bile duct had good tissue compatibility. This new artificial bile duct shows great potential for the treatment of biliary diseases.展开更多
基金State Key Laboratory for Modification of Chemical Fibers and Polymer Materials,China ( No. LZ0902 )Natural Science Foundation of Shanghai,China ( No. 10ZR1400900)
文摘The aim of this paper was to prepare an artificial bile duct using polytetrafluoroethylene（PTFE） for the development of a new treatment for biliary diseases. The basic properties of the PTFE material, such as crystallization properties, were characterized; the surface structures of the sample tubes were observed by scanning electron microscope（SEM） and water permeability test of different tubes was evaluated by osmosis device. Six Shanghai white pigs were selected to do the implantation surgery of the artificial biIe ducts. After 90 days, the artifidai bile ducts were removed from the pigs and characterized by electron microscope in order to study the tissue compatibility. The results of animal test indicated that the artificial bile duct had good tissue compatibility. This new artificial bile duct shows great potential for the treatment of biliary diseases.
