Synthetic data as an investigative tool in hypertension and renal diseases research

There is a growing body of clinical research on the utility of synthetic data derivatives,an emerging research tool in medicine.In nephrology,clinicians can use machine learning and artificial intelligence as powerful aids in their clinical decision-making while also preserving patient privacy.This is especially important given the epidemiology of chronic kidney disease,renal oncology,and hypertension worldwide.However,there remains a need to create a framework for guidance regarding how to better utilize synthetic data as a practical application in this research.

The future of artificial hibernation medicine:protection of nerves and organs after spinal cord injury

Spinal cord injury is a serious disease of the central nervous system involving irreversible nerve injury and various organ system injuries.At present,no effective clinical treatment exists.As one of the artificial hibernation techniques,mild hypothermia has preliminarily confirmed its clinical effect on spinal cord injury.However,its technical defects and barriers,along with serious clinical side effects,restrict its clinical application for spinal cord injury.Artificial hibernation is a futureoriented disruptive technology for human life support.It involves endogenous hibernation inducers and hibernation-related central neuromodulation that activate particular neurons,reduce the central constant temperature setting point,disrupt the normal constant body temperature,make the body adapt"to the external cold environment,and reduce the physiological resistance to cold stimulation.Thus,studying the artificial hibernation mechanism may help develop new treatment strategies more suitable for clinical use than the cooling method of mild hypothermia technology.This review introduces artificial hibernation technologies,including mild hypothermia technology,hibernation inducers,and hibernation-related central neuromodulation technology.It summarizes the relevant research on hypothermia and hibernation for organ and nerve protection.These studies show that artificial hibernation technologies have therapeutic significance on nerve injury after spinal co rd injury through inflammatory inhibition,immunosuppression,oxidative defense,and possible central protection.It also promotes the repair and protection of res pirato ry and digestive,cardiovascular,locomoto r,urinary,and endocrine systems.This review provides new insights for the clinical treatment of nerve and multiple organ protection after spinal cord injury thanks to artificial hibernation.At present,artificial hibernation technology is not mature,and research fa ces various challenges.Neve rtheless,the effort is wo rthwhile for the future development of medicine.

Toward Enhancing Wearability and Fashion of Wearable Supercapacitor with Modified Polyurethane Artificial Leather Electrolyte

Inspired by the sophisticated artificial leather garment industry and toward enhancing wearability of energy storage devices, we demonstrate a polyurethane artificial leather supercapacitor with large sheet electrodes embedded in theleather layer simultaneously working as a polyelectrolyte. This design totally reserves textiles underneath and thus addresses the well-known challenge of wearing comfortability. It provides a revolutionary configuration of wearable supercapacitors: the artificial leather on garment is also a supercapacitor.Unlike the polyvinyl alcohol-based acidic electrolytes, which are widely used, sodium chloride is used to modify the intrinsically fluorescent polyurethane leather for ionic transportation, which has no harm to human. The fluorescent leather supercapacitor is easily transferrable from any arbitrary substrates to form various patterns, enabling multifunctionalities of practical wearability, fashion, and energy storage.

Recovery Technology of DMF from Wet Type Polyurethane Synthetic Leather Waste Gas

A new recovery technology is developed to recycle N,N-dimethyl formamide （DMF） in waste gas from wet type polyurethane synthetic leather industry. Given that the concentration of DMF in waste gas was as low as 325.6- 688.3 mg·m^-3, it was necessary to make sure two phases contact adequately and strengthen the mass transfer by increasing contact area and enhancing the turbulence. Therefore, two-stage countercurrent absorption and two-stage fog removing system were introduced into the technology. The top section of the absorption column was filled with structured wire-ripple stainless steel packing BX500, while the lower section with sting-ripple packing CB250Y. Total height of packing material was 6 m. In addition, there were both two-stage fog removing layer and high efficiency liquid distributor at the column top. All the operating parameters, including temperature, pressure, flow rate and liquid position, could be controlled by computers without manual operation, making sure the outlet gas achieved the national emission standard that the DMF concentration should be below 40 mg·m^-3. The whole equipment could recover 237.6 t of DMF each year, with the profit up to CNY 521×10^3.

Synthesis of Hyperbranched Polymers and Its Effect on Water Vapor Permeability of Microfiber Synthetic Leather

A series of hyperbranched poly(amine-ester)polyols were synthesized by the polycondensation of N,N-diethylol-3-amine-methylpropionate(prepared by Michael addition reaction of methyl acrylate with diethanolamine)as an AB2-type monomer with trimethylol propane as the core moiety,proceeding in one-step procedure in the melt with p-toluenesulfonic acid as catalyst.The obtained monomer and polymers were characterized by FTIR and 1H-NMR spectroscopy.The solubility and surface activity in aqueous solution of the polymers were also examined.The gas permeability,water vapor permeability,and moisture absorption of microfiber synthetic leather treated by hyperbranched polymer were studied.The optimum conditions were that the dosage of dye and hyperbranched polymer was 5% and 10%,respectively.The water vapor permeability and moisture absorption of microfiber synthetic leather reached to 0.525 4 mg/(10 cm2·24 h)and 0.046 7 mg/(10 cm2·24 h).Compared with blank samples,they increased by 15% and 35%,respectively.However,the dosage of hyperbranched polymer has little influence on gas permeability of microfiber synthetic leather.SEM results show that the fiber of microfiber synthetic leather treated by hyperbranched polymer is incompact.

Application of Cationic Waterborne Polyurethane as Impregnation Material for Microfiber Synthetic Leather Base

A cationic waterborne polyurethane(CWPU) was synthesized and utilized as impregnation material for manufacturing microfiber synthetic leather base,in an attempt to decrease environmental pollution associated with organic solvents and improve simulation degree relative to genuine leather.The alkali resistance of the CWPU and four manufacture methods were investigated.Meanwhile,the dyeing properties of the microfiber synthetic leather base were studied.It was found that the CWPU displayed enough alkali resistance to endure the alkali deweighting process for microfiber synthetic leather base manufacture.In terms of bending length,bending rigidity,compression elasticity ratio and specific compression elasticity ratio of the resulting base,coagulating the impregnated CWPU with sodium hydroxide before steam treatment was the optimal method.The extent of fiber splitting and the handle of the base from this method were both similar to conventional base filled with solvent-based polyurethane(SPU).The dyeing properties of the microfiber synthetic leather base filled with CWPU were also found superior to the one filled with either anionic waterborne polyurethane(AWPU) or SPU.

Food synthetic biology-driven protein supply transition: From animal-derived production to microbial fermentation

Animal-derived protein production is one of the major traditional protein supply methods,which continues to face increasing challenges to satisfy global needs due to population growth,augmented individual protein consumption,and aggravated environmental pollution.Thus,ensuring a sustainable protein source is a considerable challenge.The emergence and development of food synthetic biology has enabled the establishment of cell factories that effectively synthesize proteins,which is an important way to solve the protein supply problem.This review aims to discuss the existing problems of traditional protein supply and to elucidate the feasibility of synthetic biology in the process of protein synthesis.Moreover,using artificial bioengineered milk and artificial bioengineered eggs as examples,the progress of food protein supply transition based on synthetic biology has been systematically summarized.Additionally,the future of food synthetic biology as a potential source of protein has been also discussed.By strengthening and innovating the application of food synthetic biology technologies,including genetic engineering and high-throughput screening methods,the current limitations of artificial foods for protein synthesis and production should be addressed.Therefore,the development and industrial production of new food resources should be explored to ensure safe,high-quality,and sustainable global protein supply.

An investigation on plasma spraying with artificial bone powder and bonding characteristics of coating

Artificial bone powder is satisfactorily deposited onto the surface of synthetic metal arthrosis(Co-Cr-Mo) with plasma spraying process. Factors influencing the quality of coating are investigated. Bond of artificial bone powder coating sprayed with different parameters is measured. and the coatings are anlyzed with metallographic examination and electron probe analysis. Experiments show that artificial bone powder coating sprayed onto synthetic metal arthrosis with satisfactory bond strength can be obtained by manipulating plasma spraying.

Interaction and the Genesis of Experience: A Phenomenological Contribution for Meaningful Embodied Artificial Intelligence

In this article I will address the issue of the meaning of Embodied Artificial Intelligence(EAI)as it is configured today.My starting point is the refined interactive perspective on the semantics of EAI,as was recently suggested by Froese and colleagues.This perspective rests on the assumption that the concept of human bodily subjectivity must be extended to include meaning-making processes,which are enabled by advanced AI systems that may be incorporated in the human biological body.After having clarified the technical background,I will introduce the genetic component of the phenomenological method as a suitable tool to face the aforementioned issue.Towards this end,I will place the genetic method in the context of the so-called New Human-Machine Interaction(New HMI).I will further outline a genetic phenomenology of visual embodiment,suggesting a futuristic application based on the thesis of the“technological supplementation of phenomenological methodology”through the synthetic method.The case at stake is that of patients with a severe clinical picture characterised by the loss of corneal function,who in the near future could be treated with synthetic corneal prosthetic implants produced by a 3D bio-printing process by using an advanced EAI technique.I will conclude this article with a brief review of the main problems that still remain open.

Wearable synthetic leather-based high-performance X-ray shielding materials enabled by the plant polyphenol-and hierarchical structure-facilitated dispersion

Effective protection against X-ray is the premise of utilizing the X-ray,thus it is critical to develop novel X-ray shielding materials with both low density and high X-ray attenuation efficiency.As the even distribution of high-Z element components is of great significance for increasing the attenuation efficiency of X-ray shielding materials,in this study,the microfiber membrane(MFM),a type of synthetic leather featuring hierarchical structure was chosen to provide large surface area for the dispersion of rare earth(RE)element.Meanwhile,plant polyphenol was utilized to achieve the stable loading and uniform dispersion of the Ce or Er into MFM.Benefiting from the assistance of polyphenol and hierarchical structure of MFM,the even dispersion of RE element was successfully realized.The resultant shielding materials displayed approximately 10%superior X-ray attenuation efficiency compared to that without polyphenol,and an averagely 9%increment in X-ray attenuation efficiency than that without hierarchical structure.Moreover,the obtained composite with a thickness of 2.8 mm displayed superior X-ray shielding performance compared to 0.25 mm lead sheet in 16-83 keV and retained an ultralow density of 1.4 g cm^(-3).Our research results would shed new light on the manufacture of high-performance X-ray shielding materials with excellent X-ray shielding performance.

Synthetic optical vortex beams from the analogous trajectory change of an artificial satellite

We propose a method to generate specially shaped high-order singular beams of pre-designed intensity distributions. Such a method does not a priori assume a phase formula, but rather relies on the 'cake-cutting and assembly' approach to achieve the azimuthal phase gradient for beam shaping, inspired by the orbital motion trajectory change of an artificial satellite. Based on our method, several typical vortex beams with desired intensity patterns are experimentally generated. As an example, we realize optical trapping and transportation of microorganisms with a triangle-shaped vortex beam, demonstrating the applicability of such unconventional vortex beams in optical trapping and manipulation.

基于人工智能的皮革企业物流系统设计研究

皮革产业对物流体系具有极高的依赖性,物流水平可以直接影响企业的经营成本、产业效益等。以人工智能为基础提出了一种皮革企业物流系统的设计思路,从设备层、边缘层、云端应用层3个视角构建了具体的皮革企业物流系统框架,实现了皮革企业物流系统的数据采集与传送、物流业务协调与系统互联、业务和数据建模等功能,旨在为人工智能与皮革产业物流体系的融合提供借鉴。

How does bio-based leather become the favorite of luxury brands?

Artificial leather and synthetic leather products have more than 60 years of development history,because the cost of artificial leather is lower than real leather,the manufacturing process is relatively simple,widely used in textile,automotive and furniture decoration fields.

大数据与计算模型

当前,人工智能持续升温,大语言模型吸引了众多人士的关注,并在全球范围内掀起了一股热潮。人工智能的成功本质上不是大算力“出奇迹”,而是改变了计算模型。首先,肯定了数据对于人工智能的基础性作用,指出合成数据将是未来数据的主要来源。然后,回顾了计算模型的发展历程,重点介绍了神经网络模型与图灵模型的历史性竞争;指出了大模型的重要标志是机器涌现智能,强调大模型的本质是“压缩”;分析了大模型产生“幻觉”的原因。最后,呼吁科技界在智能化科研中要重视大科学模型。

合成革材料在球类运动用品中的差异与优势比较分析

球类运动是当下热门的运动种类,相关用品的材料制备是目前我国体育产业领域的重点方向之一。以篮球、足球、排球等球类运动为例,通过对球类运动用品进行分类,总结了不同球类运动用品的需求差异、性能差异,对球类、运动鞋、防护用品等相关运动用品合成革材料的制备原理和工艺分别进行分析,应用合成革制备球类运动产品,能够充分利用合成革材料种类丰富、可加工性强等优势,满足不同球类运动用品的个性化需求,作为传统天然皮革的有效替代物,合成革在球类运动用品加工领域具有极为广阔的应用前景。旨在为体育产业与合成革材料的融合提供借鉴。

体育服饰用超细纤维合成革针刺非织造基布的力学性能表征

为有效解决开纤处理后海岛超细纤维针刺非织造基布致密性低且针刺痕迹等一系列问题,以促使其在体育服饰用超细纤维合成革中广泛应用,本文基于针刺法将高收缩聚酯纤维掺入海岛超细纤维合成革非织造基布,以制备生成了超细纤维合成革针刺非织造基布,并对其力学性能进行了测试表征。结果发现,随着高收缩聚酯纤维掺入量增加,超细纤维合成革针刺非织造基布断裂强度与撕裂强度皆逐渐增大;透湿性与吸湿性先降低后升高;热收缩率逐步增高;耐磨性逐渐提升,且基布均匀度较好;弯曲长度与弯曲刚度皆逐渐增大,柔软度随之降低;以针刺非织造基布为原料制成的体育服饰用超细纤维合成革表面平整且光滑,底面平整且粗糙度适中,致密性较好,且断裂强度、撕裂强度、透湿性与吸水性均表现优异。

运动器材用水性聚氨酯合成革胶膜制备及其性能研究

为改善运动器材用水性聚氨酯合成革综合性能,本文以聚丙二醇2000与二月桂酸二丁基锡为原料,以硅烷偶联剂为改性剂制备了水性聚氨酯合成革胶膜,并对其性能进行了测试表征。结果表明,随着硅烷偶联剂用量增加,合成革用水性聚氨酯乳液由透明变为白色,粒径逐渐增大,黏度逐步增大,离心稳定性较好;随着硅烷偶联剂用量增加,水性聚氨酯合成革胶膜拉伸强度与断裂伸长率均先增后减,杨氏模量先缓慢增大后迅速增大,剥离强度先增后减,当用量为6 g时胶膜力学性能整体表现最优;随着硅烷偶联剂用量增加,水性聚氨酯合成革胶膜吸水率先减后增,水接触角逐渐增大,当用量为6 g时胶膜耐水性能整体表现最佳。

体育用品合成革用水性聚氨酯热熔胶研究

为顺应绿色环保理念,保障体育运动装备综合性能,优化体育用品用水性聚氨酯合成革的力学性能与粘接性能,制备环保型水性聚氨酯热熔胶以粘接、修补合成革具有非常重要的现实意义。据此,本文以甲苯二异氰酸酯、聚己二酸-1,4-丁二醇酯二醇等为原料制备了水性聚氨酯乳液,并以接枝剂甲基丙烯酸羟乙酯改性制备了体育合成革用水性聚氨酯热熔胶,同时对其性能进行了测试表征。结果发现,随着接枝剂甲基丙烯酸羟乙酯用量的增加,体育用品合成革用水性聚氨酯热熔胶拉伸强度与断裂伸长率随之增大,剥离强度与剪切强度逐步增大,水接触角逐渐增大,而吸水率明显下降,表明接枝剂甲基丙烯酸羟乙酯的掺入,可有效改善水性聚氨酯热熔胶的机械性能、粘接性能,以及耐水性与疏水性。

基于人工智能的皮革材料缺陷检测与识别方法研究

本文在分析现代皮革材料缺陷检测与识别方法的基础上,尝试将人工智能技术融入该类材料的检测环节,构建了一种基于深度学习无监督+二分类需求的皮革材料缺陷检测智能化系统,并对该系统工作时的缺陷检测效率、误检率、缺陷识别情况等进行测试。结果表明,该方法以深度学习为核心,可以获得较高的皮革材料缺陷检测效率、较低的误检率和较好的自主学习能力。

基于卷积神经网络的柔性皮革材料缺陷无损检测技术研究

卷积神经网络是一种类似深度学习模型的多层感知器,被广泛应用于分析视觉图像。本文以无损化、高效化、智能化检测为目标,构建了一种基于卷积神经网络的柔性皮革材料缺陷检测技术流程,针对该流程对柔性皮革材料缺陷检测的效果进行了案例分析,旨在为皮革领域材料无损检测技术的发展提供借鉴。