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Design and Synthesis of Novel Aryloxyalkyl-arylpiperazine Derivatives as α_(1A)-Adrenoceptor Antagonists
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作者 HaoFANG MinYongLI +2 位作者 LinXIA ZhenZhouJIANG ZhiZhenLU 《Chinese Chemical Letters》 SCIE CAS CSCD 2005年第4期445-448,共4页
A series of 1-[2-(substituted phenoxy)ethyl]-4-(2-methoxyphenyl)-piperazine deriva- tives have been synthesized. The radioligand receptor binding assay indicated that most of them bind with α1-adrenoceptor specific... A series of 1-[2-(substituted phenoxy)ethyl]-4-(2-methoxyphenyl)-piperazine deriva- tives have been synthesized. The radioligand receptor binding assay indicated that most of them bind with α1-adrenoceptor specifically, and one of the compound possessed subtype A selectivity. 展开更多
关键词 Α1-ADRENOCEPTOR ANTAGONIST aryloxyalkyl-arylpiperazine.
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