Intelligent personal assistants play a pivotal role in in-vehicle systems,significantly enhancing life efficiency,driving safety,and decision-making support.In this study,the multi-modal design elements of intelligent...Intelligent personal assistants play a pivotal role in in-vehicle systems,significantly enhancing life efficiency,driving safety,and decision-making support.In this study,the multi-modal design elements of intelligent personal assistants within the context of visual,auditory,and somatosensory interactions with drivers were discussed.Their impact on the driver’s psychological state through various modes such as visual imagery,voice interaction,and gesture interaction were explored.The study also introduced innovative designs for in-vehicle intelligent personal assistants,incorporating design principles such as driver-centricity,prioritizing passenger safety,and utilizing timely feedback as a criterion.Additionally,the study employed design methods like driver behavior research and driving situation analysis to enhance the emotional connection between drivers and their vehicles,ultimately improving driver satisfaction and trust.展开更多
In this paper, we propose a novel AIenabled space-air-ground integrated networks(SAGIN). This new integrated networks architecture consists of LEO satellites and civil aircrafts carrying aerial base stations, called &...In this paper, we propose a novel AIenabled space-air-ground integrated networks(SAGIN). This new integrated networks architecture consists of LEO satellites and civil aircrafts carrying aerial base stations, called "civil aircraft assisted SAGIN(CAA-SAGIN)". The assistance of civil aircrafts can reduce the stress of satellite networks, improve the performance of SAGIN, decrease the construction cost and save space resources. Taking the Chinese mainland as an example, this paper has analyzed the distribution of civil aircrafts, and obtained the coverage characteristics of civil aircraft assisted networks(CAAN). Taking Starlink as the benchmark, this paper has calculated the service gap of CAAN, and designed the joint coverage constellation. The simulation results prove that the number of satellites in CAASAGIN can be greatly reduced with the assistance of civil aircrafts at the same data rate.展开更多
Objectives: Computational study will help us in reducing the experimental work. The process of drug discovery involves the designing of molecules with appropriate pharmacophores with the help of various soft wares. T...Objectives: Computational study will help us in reducing the experimental work. The process of drug discovery involves the designing of molecules with appropriate pharmacophores with the help of various soft wares. The purpose of this paper is to study the probable binding modes of fatty acids on fatty acids after enzymatic hydrolysis of the FAAH (fatty acid amide hydrolase) in different extracts of flowers, leaves, stem bark, root bark and nuts of Semecarpus anacardiurn L. f. by using molecular modeling study and computer assisted drug designing. Nuts yielded 20 fatty acids including saturated, ω-3 unsaturated, ω-6 unsaturated, ω-7 unsaturated and ω-9 unsaturated fatty acids. Based on IR, IH NMR, 13C NMR, MS (mass) spectrometry, GC analysis, the structural elucidation of these isolated fatty acids was established. Methods: A dataset comprising of 20 fatty acids were drawn in ChemDraw and converted into 3D-molecules with all possible tautomers and chiral centers. The minimization of molecules was carried out using PRCG (Polak-Ribiere Conjugate Gradient) method with maximum of 5000 iterations. The minimized compounds were used for protein preparation. The crystal structure of human FAAH (PDB ID: 3K84) is prepared and selected for the docking studies of 20 fatty acids using Schr6dinger docking program module.. Conclusions: In this study, we carried out the molecular docking studies in order to understand the probable binding mode of 20 fatty acids in FAAH from which we identified key active site residues for FAAH, thereby it can be used to design the novel compounds for FAAH targets.展开更多
A compound machine tool was designed, which combined rotary ultrasonic assisted grinding, electrical discharge machining(EDM) and multi-axis milling. Experimental results indicated that its positioning accuracy was le...A compound machine tool was designed, which combined rotary ultrasonic assisted grinding, electrical discharge machining(EDM) and multi-axis milling. Experimental results indicated that its positioning accuracy was less than 5.6 μm and its repetitive positioning accuracy was less than 1.8 μm; the vibration amplitude of ultrasonic grinding system was uniform and stable, and the EDM system worked well and stably.A smooth surface of K9 optical glass component was achieved by the grinding method.展开更多
This paper focuses on the use of models for increasing the precision of estimators in large-area forest surveys. It is motivated by the increasing availability of remotely sensed data, which facilitates the developmen...This paper focuses on the use of models for increasing the precision of estimators in large-area forest surveys. It is motivated by the increasing availability of remotely sensed data, which facilitates the development of models predicting the variables of interest in forest surveys. We present, review and compare three different estimation frameworks where models play a core role: model-assisted, model-based, and hybrid estimation. The first two are well known, whereas the third has only recently been introduced in forest surveys. Hybrid inference mixes design- based and model-based inference, since it relies on a probability sample of auxiliary data and a model predicting the target variable from the auxiliary data.We review studies on large-area forest surveys based on model-assisted, model- based, and hybrid estimation, and discuss advantages and disadvantages of the approaches. We conclude that no general recommendations can be made about whether model-assisted, model-based, or hybrid estimation should be preferred. The choice depends on the objective of the survey and the possibilities to acquire appropriate field and remotely sensed data. We also conclude that modelling approaches can only be successfully applied for estimating target variables such as growing stock volume or biomass, which are adequately related to commonly available remotely sensed data, and thus purely field based surveys remain important for several important forest parameters.展开更多
The traceability management system for pigs based on personal digital assistant (PDA) was constructed by software engineering method to provide the traceability management for pork safety. This traceability system i...The traceability management system for pigs based on personal digital assistant (PDA) was constructed by software engineering method to provide the traceability management for pork safety. This traceability system included information managements for pig breeding and pig quaran- tine inspection supervision. It also realized the record and supervision of pig information, feed usage, veterinary drug usage and quarantine inspec- tion. We mainly introduced the designs of systemic structure and functional structure of the traceability system and key techniques of system imple- mentation.展开更多
In this paper, the estimation capacities of the response surface methodology (RSM) and artificial neural network (ANN), in a microwave-assisted extraction method to determine the amount of zinc in fish samples were in...In this paper, the estimation capacities of the response surface methodology (RSM) and artificial neural network (ANN), in a microwave-assisted extraction method to determine the amount of zinc in fish samples were investigated. The experiments were carried out based on a 3-level, 4-variable Box–Behnken design. The amount of zinc was considered as a function of four independent variables, namely irradiation power, irradiation time, nitric acid concentration, and temperature. The RSM results showed the quadratic polynomial model can be used to describe the relationship between the various factors and the response. Using the ANN analysis, the optimal configuration of the ANN model was found to be 4-10-1. After predicting the model using RSM and ANN, two methodologies were then compared for their predictive capabilities. The results showed that the ANN model is much more accurate in prediction as compared to the RSM.展开更多
Transformation and innovation of assistance model promote the transition of urban social assistance building to multi-functional building. This paper, on the basis of analyzing complexity and peculiarity of urban soci...Transformation and innovation of assistance model promote the transition of urban social assistance building to multi-functional building. This paper, on the basis of analyzing complexity and peculiarity of urban social assistance building, as well as researches and practices of sustainable improvement of domestic architecture, proposed environmental, social and economic objectives of the sustainable improvement of urban social assistance building, and elaborated design strategies from the perspectives of site selection and its impact on environment, application, evaluation and utilization of ecological technologies, reform of old buildings, flexible internal layout of building and combination of routine use and disaster use design, so as to improve social benefits and social assessment of assistance buildings sustainably, and to balance humanistic concerns and social resource input.展开更多
The Epitaxial GaN thin films have been fabricated by Ion Beam Assisted Deposition (IBAD) process using nitrogen ions with hyperthermal energies on the polyimides polymer substrates. By applying with the Reflection of ...The Epitaxial GaN thin films have been fabricated by Ion Beam Assisted Deposition (IBAD) process using nitrogen ions with hyperthermal energies on the polyimides polymer substrates. By applying with the Reflection of High-Energy Electron Diffraction (RHEED), Scanning Electron Microscopy (SEM) and Quantum Design Physical Properties Measurement System, the behaviour of hexagonal GaN thin films is investigated. The result showed that the high quality of the deposited GaN layers kept appearing for many parameters depending on the temperature greatly. The behaviour of high quality of epitaxial GaN coating on the polyimide polymer substrates is a promising material for optoelectronic devices and semiconductor devices application.展开更多
The full-length of intact Zea mays gene for phosphoenolpyruvate carboxylase gene (ZmC4Ppc) is 6 781 bp. The products of PCR for this gene were not clear with poor repeatability, resulting in that it was difficult fo...The full-length of intact Zea mays gene for phosphoenolpyruvate carboxylase gene (ZmC4Ppc) is 6 781 bp. The products of PCR for this gene were not clear with poor repeatability, resulting in that it was difficult for marker-assisted selection (MAS) both in rice and maize. For selecting the markers for MAS, sequences presented only in maize rather than in rice were identified by BLAST, and used for primer design using Primer Premier 5.0. A pair of specific primer termed MRpc (Forward: 5' AAGCAGGGAAGCGAGACG 3', Reverse: 5' GATTGCCGCCAGCAGTAG 3') was used for selection of transformed rice, and ZmC4Ppc could be highly and constitutively expressed at each tested developmental stages in the transformed rice selected by using MRpc. Thus, MRpc was used for MAS of progenies carrying ZmC4Ppc gene in rice and some restorer lines with ZmC4Ppc (e.g. FPM881) derived from ZmC4Ppc-transformed Kitaake backcrossed with a restorer line Shuhui 881 were obtained. The analyses on genetic background, PEPCase activity, net photosynthetic rate, general combining ability (GCA) and specific combining ability (SCA) of FPM881 showed that similarity of genetic background reached above 95%, the PEPCase and net photosynthetic rate were higher than those of the control, and some of the progenies carrying ZmC4Ppc gene had better GCA and SCA for grain yield per plant, number of panicles per plant, and 1000-grain weight than those of the control. This suggested that the introduction of maize ZmC4Ppc gene via MAS and its stable expression could increase grain yield of rice and would likely provide a pathway for rice varietal improvement.展开更多
Objectives Renal replacement therapy(RRT)is increasingly adopted for critically ill patients diagnosed with acute kidney injury,but the optimal time for initiation remains unclear and prognosis is uncertain,leading to...Objectives Renal replacement therapy(RRT)is increasingly adopted for critically ill patients diagnosed with acute kidney injury,but the optimal time for initiation remains unclear and prognosis is uncertain,leading to medical complexity,ethical conflicts,and decision dilemmas in intensive care unit(ICU)settings.This study aimed to develop a decision aid(DA)for the family surrogate of critically ill patients to support their engagement in shared decision-making process with clinicians.Methods Development of DA employed a systematic process with user-centered design(UCD)principle,which included:(i)competitive analysis:searched,screened,and assessed the existing DAs to gather insights for design strategies,developmental techniques,and functionalities;(ii)user needs assessment:interviewed family surrogates in our hospital to explore target user group's decision-making experience and identify their unmet needs;(iii)evidence syntheses:integrate latest clinical evidence and pertinent information to inform the content development of DA.Results The competitive analysis included 16 relevant DAs,from which we derived valuable insights using existing resources.User decision needs were explored among a cohort of 15 family surrogates,revealing four thematic issues in decision-making,including stuck into dilemmas,sense of uncertainty,limited capacity,and delayed decision confirmation.A total of 27 articles were included for evidence syntheses.Relevant decision making knowledge on disease and treatment,as delineated in the literature sourced from decision support system or clinical guidelines,were formatted as the foundational knowledge base.Twenty-one items of evidence were extracted and integrated into the content panels of benefits and risks of RRT,possible outcomes,and reasons to choose.The DA was drafted into a web-based phototype using the elements of UCD.This platform could guide users in their preparation of decision-making through a sequential four-step process:identifying treatment options,weighing the benefits and risks,clarifying personal preferences and values,and formulating a schedule for formal shared decision-making with clinicians.Conclusions We developed a rapid prototype of DA tailored for family surrogate decision makers of critically ill patients in need of RRT in ICU setting.Future studies are needed to evaluate its usability,feasibility,and clinical effects of this intervention.展开更多
Blackmagic Design发布针对Blackmagic Video Assist 2.3的重要更新,为两款型号添加了3D LUT监看功能。升级到Video Assist 2.3版后,在使用5英寸和7英寸Blackmagic Video Assist型号时,用户可加载最多6个3D LUT用于现场视频监看。这6个3...Blackmagic Design发布针对Blackmagic Video Assist 2.3的重要更新,为两款型号添加了3D LUT监看功能。升级到Video Assist 2.3版后,在使用5英寸和7英寸Blackmagic Video Assist型号时,用户可加载最多6个3D LUT用于现场视频监看。这6个3D LUT可被存储,也可被随时调用,而且5英寸的Blackmagic Video Assist型号和7英寸的Blackmagic Video Assist 4K型号均具备这项新功能。展开更多
In order to restore force sensation to robot-assisted minimally invasive surgery(RMIS),design and performance evaluation of a miniature 6-axis force/torque sensor for force feedback is presented.Based on the resistive...In order to restore force sensation to robot-assisted minimally invasive surgery(RMIS),design and performance evaluation of a miniature 6-axis force/torque sensor for force feedback is presented.Based on the resistive sensing method,a flexural-hinged Stewart platform is designed as the flexible structure,and a straightforward optimization method considering the force and sensitivity isotropy of the sensor is proposed to determine geometric parameters which are best suited for the given external loads.The accuracy of this method is preliminarily discussed by finite element methods(FEMs).The sensor prototype is fabricated with the development of the electronic system.Calibration and dynamic loading tests for this sensor prototype are carried out.The working ranges of this sensor prototype are 30 N and 300 N·mm,and resolutions are 0.08 N in radial directions,0.25 N in axial direction,and 2.4 N·mm in rotational directions.It also exhibits a good capability for a typical dynamic force sensing at a frequency close to the normal heart rate of an adult.The sensor is compatible with surgical instruments for force feedback in RMIS.展开更多
The central treasury is implementing six measures this year to help small-and medium-sized enterprises (SMEs) meet the challenges they face, according to the Ministry of Finance.
In times of digitalisation, visual assistance systems in assembly are increasingly important. The design of these assembly systems needs to be highly complex to meet the requirements. Due to the increasing number of v...In times of digitalisation, visual assistance systems in assembly are increasingly important. The design of these assembly systems needs to be highly complex to meet the requirements. Due to the increasing number of variants in production processes, as well as shorter innovation and product life cycles, assistance systems should improve quality and reduce complexity of assembly processes. However, many large kitchen manufacturers still assemble kitchen cabinets manually, due to the high variety of components, such as rails and fittings. This paper focuses on the analysis and evaluation of virtual assistance systems to improve quality and usability in individualised kitchen cabinet assembly processes at a large German manufacturer. A solution is identified and detailed.展开更多
In the 6th edition of the Chinese Space Trajectory Design Competition held in 2014, a near-Earth asteroid sample-return trajectory design problem was released, in which the motion of the spacecraft is modeled in multi...In the 6th edition of the Chinese Space Trajectory Design Competition held in 2014, a near-Earth asteroid sample-return trajectory design problem was released, in which the motion of the spacecraft is modeled in multi-body dynamics, considering the gravitational forces of the Sun, Earth, and Moon. It is proposed that an electric-propulsion spacecraft initially parking in a circular 200-kin-altitude low Earth orbit is expected to rendezvous with an asteroid and carry as much sample as possible back to the Earth in a 10-year time frame. The team from the Technology and Engineering Center for Space Utilization, Chinese Academy of Sciences has reported a solution with an asteroid sample mass of 328 tons, which is ranked first in the competition. In this article, we will present our design and optimization methods, primarily including overall analysis, target selection, escape from and capture by the Earth-Moon system, and optimization of impulsive and low-thrust trajectories that are modeled in multi-body dynamics. The orbital resonance concept and lunar gravity assists are considered key techniques employed for trajectory design. The reported solution, preliminarily revealing the feasibility of returning a hundreds-of-tons asteroid or asteroid sample, envisions future space missions relating to near-Earth asteroid exploration.展开更多
Asteroid exploration is one of the most sophisticated missions currently being investigated. Gravity-assist trajectories have proven valuable in interplanetary missions such as the Pioneer, Voyager and Galileo. In thi...Asteroid exploration is one of the most sophisticated missions currently being investigated. Gravity-assist trajectories have proven valuable in interplanetary missions such as the Pioneer, Voyager and Galileo. In this paper, we design interplanetary trajectory for main belt asteroid exploration mission with the Mars gravity-assist (MGA) using “pork chop” plots and patched-conic theory and give some initial valuable trajectory parameters on main belt asteroid exploration mission with MGA.展开更多
文摘Intelligent personal assistants play a pivotal role in in-vehicle systems,significantly enhancing life efficiency,driving safety,and decision-making support.In this study,the multi-modal design elements of intelligent personal assistants within the context of visual,auditory,and somatosensory interactions with drivers were discussed.Their impact on the driver’s psychological state through various modes such as visual imagery,voice interaction,and gesture interaction were explored.The study also introduced innovative designs for in-vehicle intelligent personal assistants,incorporating design principles such as driver-centricity,prioritizing passenger safety,and utilizing timely feedback as a criterion.Additionally,the study employed design methods like driver behavior research and driving situation analysis to enhance the emotional connection between drivers and their vehicles,ultimately improving driver satisfaction and trust.
基金supported by National Nature Science Foundation of China (No. 61871155)。
文摘In this paper, we propose a novel AIenabled space-air-ground integrated networks(SAGIN). This new integrated networks architecture consists of LEO satellites and civil aircrafts carrying aerial base stations, called "civil aircraft assisted SAGIN(CAA-SAGIN)". The assistance of civil aircrafts can reduce the stress of satellite networks, improve the performance of SAGIN, decrease the construction cost and save space resources. Taking the Chinese mainland as an example, this paper has analyzed the distribution of civil aircrafts, and obtained the coverage characteristics of civil aircraft assisted networks(CAAN). Taking Starlink as the benchmark, this paper has calculated the service gap of CAAN, and designed the joint coverage constellation. The simulation results prove that the number of satellites in CAASAGIN can be greatly reduced with the assistance of civil aircrafts at the same data rate.
文摘Objectives: Computational study will help us in reducing the experimental work. The process of drug discovery involves the designing of molecules with appropriate pharmacophores with the help of various soft wares. The purpose of this paper is to study the probable binding modes of fatty acids on fatty acids after enzymatic hydrolysis of the FAAH (fatty acid amide hydrolase) in different extracts of flowers, leaves, stem bark, root bark and nuts of Semecarpus anacardiurn L. f. by using molecular modeling study and computer assisted drug designing. Nuts yielded 20 fatty acids including saturated, ω-3 unsaturated, ω-6 unsaturated, ω-7 unsaturated and ω-9 unsaturated fatty acids. Based on IR, IH NMR, 13C NMR, MS (mass) spectrometry, GC analysis, the structural elucidation of these isolated fatty acids was established. Methods: A dataset comprising of 20 fatty acids were drawn in ChemDraw and converted into 3D-molecules with all possible tautomers and chiral centers. The minimization of molecules was carried out using PRCG (Polak-Ribiere Conjugate Gradient) method with maximum of 5000 iterations. The minimized compounds were used for protein preparation. The crystal structure of human FAAH (PDB ID: 3K84) is prepared and selected for the docking studies of 20 fatty acids using Schr6dinger docking program module.. Conclusions: In this study, we carried out the molecular docking studies in order to understand the probable binding mode of 20 fatty acids in FAAH from which we identified key active site residues for FAAH, thereby it can be used to design the novel compounds for FAAH targets.
基金Supported by the National High Technology Research and Development Program of China("863" Program,No.2009AA044204)
文摘A compound machine tool was designed, which combined rotary ultrasonic assisted grinding, electrical discharge machining(EDM) and multi-axis milling. Experimental results indicated that its positioning accuracy was less than 5.6 μm and its repetitive positioning accuracy was less than 1.8 μm; the vibration amplitude of ultrasonic grinding system was uniform and stable, and the EDM system worked well and stably.A smooth surface of K9 optical glass component was achieved by the grinding method.
文摘This paper focuses on the use of models for increasing the precision of estimators in large-area forest surveys. It is motivated by the increasing availability of remotely sensed data, which facilitates the development of models predicting the variables of interest in forest surveys. We present, review and compare three different estimation frameworks where models play a core role: model-assisted, model-based, and hybrid estimation. The first two are well known, whereas the third has only recently been introduced in forest surveys. Hybrid inference mixes design- based and model-based inference, since it relies on a probability sample of auxiliary data and a model predicting the target variable from the auxiliary data.We review studies on large-area forest surveys based on model-assisted, model- based, and hybrid estimation, and discuss advantages and disadvantages of the approaches. We conclude that no general recommendations can be made about whether model-assisted, model-based, or hybrid estimation should be preferred. The choice depends on the objective of the survey and the possibilities to acquire appropriate field and remotely sensed data. We also conclude that modelling approaches can only be successfully applied for estimating target variables such as growing stock volume or biomass, which are adequately related to commonly available remotely sensed data, and thus purely field based surveys remain important for several important forest parameters.
基金supported by the Agricultural Science and Technology Innovation Project of Yunnan Province(2008LA020)sub-topic of National Key Technology R&D Program(2006BAD14B04)
文摘The traceability management system for pigs based on personal digital assistant (PDA) was constructed by software engineering method to provide the traceability management for pork safety. This traceability system included information managements for pig breeding and pig quaran- tine inspection supervision. It also realized the record and supervision of pig information, feed usage, veterinary drug usage and quarantine inspec- tion. We mainly introduced the designs of systemic structure and functional structure of the traceability system and key techniques of system imple- mentation.
文摘In this paper, the estimation capacities of the response surface methodology (RSM) and artificial neural network (ANN), in a microwave-assisted extraction method to determine the amount of zinc in fish samples were investigated. The experiments were carried out based on a 3-level, 4-variable Box–Behnken design. The amount of zinc was considered as a function of four independent variables, namely irradiation power, irradiation time, nitric acid concentration, and temperature. The RSM results showed the quadratic polynomial model can be used to describe the relationship between the various factors and the response. Using the ANN analysis, the optimal configuration of the ANN model was found to be 4-10-1. After predicting the model using RSM and ANN, two methodologies were then compared for their predictive capabilities. The results showed that the ANN model is much more accurate in prediction as compared to the RSM.
文摘Transformation and innovation of assistance model promote the transition of urban social assistance building to multi-functional building. This paper, on the basis of analyzing complexity and peculiarity of urban social assistance building, as well as researches and practices of sustainable improvement of domestic architecture, proposed environmental, social and economic objectives of the sustainable improvement of urban social assistance building, and elaborated design strategies from the perspectives of site selection and its impact on environment, application, evaluation and utilization of ecological technologies, reform of old buildings, flexible internal layout of building and combination of routine use and disaster use design, so as to improve social benefits and social assessment of assistance buildings sustainably, and to balance humanistic concerns and social resource input.
文摘The Epitaxial GaN thin films have been fabricated by Ion Beam Assisted Deposition (IBAD) process using nitrogen ions with hyperthermal energies on the polyimides polymer substrates. By applying with the Reflection of High-Energy Electron Diffraction (RHEED), Scanning Electron Microscopy (SEM) and Quantum Design Physical Properties Measurement System, the behaviour of hexagonal GaN thin films is investigated. The result showed that the high quality of the deposited GaN layers kept appearing for many parameters depending on the temperature greatly. The behaviour of high quality of epitaxial GaN coating on the polyimide polymer substrates is a promising material for optoelectronic devices and semiconductor devices application.
文摘The full-length of intact Zea mays gene for phosphoenolpyruvate carboxylase gene (ZmC4Ppc) is 6 781 bp. The products of PCR for this gene were not clear with poor repeatability, resulting in that it was difficult for marker-assisted selection (MAS) both in rice and maize. For selecting the markers for MAS, sequences presented only in maize rather than in rice were identified by BLAST, and used for primer design using Primer Premier 5.0. A pair of specific primer termed MRpc (Forward: 5' AAGCAGGGAAGCGAGACG 3', Reverse: 5' GATTGCCGCCAGCAGTAG 3') was used for selection of transformed rice, and ZmC4Ppc could be highly and constitutively expressed at each tested developmental stages in the transformed rice selected by using MRpc. Thus, MRpc was used for MAS of progenies carrying ZmC4Ppc gene in rice and some restorer lines with ZmC4Ppc (e.g. FPM881) derived from ZmC4Ppc-transformed Kitaake backcrossed with a restorer line Shuhui 881 were obtained. The analyses on genetic background, PEPCase activity, net photosynthetic rate, general combining ability (GCA) and specific combining ability (SCA) of FPM881 showed that similarity of genetic background reached above 95%, the PEPCase and net photosynthetic rate were higher than those of the control, and some of the progenies carrying ZmC4Ppc gene had better GCA and SCA for grain yield per plant, number of panicles per plant, and 1000-grain weight than those of the control. This suggested that the introduction of maize ZmC4Ppc gene via MAS and its stable expression could increase grain yield of rice and would likely provide a pathway for rice varietal improvement.
文摘Objectives Renal replacement therapy(RRT)is increasingly adopted for critically ill patients diagnosed with acute kidney injury,but the optimal time for initiation remains unclear and prognosis is uncertain,leading to medical complexity,ethical conflicts,and decision dilemmas in intensive care unit(ICU)settings.This study aimed to develop a decision aid(DA)for the family surrogate of critically ill patients to support their engagement in shared decision-making process with clinicians.Methods Development of DA employed a systematic process with user-centered design(UCD)principle,which included:(i)competitive analysis:searched,screened,and assessed the existing DAs to gather insights for design strategies,developmental techniques,and functionalities;(ii)user needs assessment:interviewed family surrogates in our hospital to explore target user group's decision-making experience and identify their unmet needs;(iii)evidence syntheses:integrate latest clinical evidence and pertinent information to inform the content development of DA.Results The competitive analysis included 16 relevant DAs,from which we derived valuable insights using existing resources.User decision needs were explored among a cohort of 15 family surrogates,revealing four thematic issues in decision-making,including stuck into dilemmas,sense of uncertainty,limited capacity,and delayed decision confirmation.A total of 27 articles were included for evidence syntheses.Relevant decision making knowledge on disease and treatment,as delineated in the literature sourced from decision support system or clinical guidelines,were formatted as the foundational knowledge base.Twenty-one items of evidence were extracted and integrated into the content panels of benefits and risks of RRT,possible outcomes,and reasons to choose.The DA was drafted into a web-based phototype using the elements of UCD.This platform could guide users in their preparation of decision-making through a sequential four-step process:identifying treatment options,weighing the benefits and risks,clarifying personal preferences and values,and formulating a schedule for formal shared decision-making with clinicians.Conclusions We developed a rapid prototype of DA tailored for family surrogate decision makers of critically ill patients in need of RRT in ICU setting.Future studies are needed to evaluate its usability,feasibility,and clinical effects of this intervention.
文摘Blackmagic Design发布针对Blackmagic Video Assist 2.3的重要更新,为两款型号添加了3D LUT监看功能。升级到Video Assist 2.3版后,在使用5英寸和7英寸Blackmagic Video Assist型号时,用户可加载最多6个3D LUT用于现场视频监看。这6个3D LUT可被存储,也可被随时调用,而且5英寸的Blackmagic Video Assist型号和7英寸的Blackmagic Video Assist 4K型号均具备这项新功能。
基金Project(SS2012AA041601)supported by National High Technology Research and Development Program of ChinaProject(81201150)supported by the National Natural Science Foundation of China
文摘In order to restore force sensation to robot-assisted minimally invasive surgery(RMIS),design and performance evaluation of a miniature 6-axis force/torque sensor for force feedback is presented.Based on the resistive sensing method,a flexural-hinged Stewart platform is designed as the flexible structure,and a straightforward optimization method considering the force and sensitivity isotropy of the sensor is proposed to determine geometric parameters which are best suited for the given external loads.The accuracy of this method is preliminarily discussed by finite element methods(FEMs).The sensor prototype is fabricated with the development of the electronic system.Calibration and dynamic loading tests for this sensor prototype are carried out.The working ranges of this sensor prototype are 30 N and 300 N·mm,and resolutions are 0.08 N in radial directions,0.25 N in axial direction,and 2.4 N·mm in rotational directions.It also exhibits a good capability for a typical dynamic force sensing at a frequency close to the normal heart rate of an adult.The sensor is compatible with surgical instruments for force feedback in RMIS.
文摘The central treasury is implementing six measures this year to help small-and medium-sized enterprises (SMEs) meet the challenges they face, according to the Ministry of Finance.
文摘In times of digitalisation, visual assistance systems in assembly are increasingly important. The design of these assembly systems needs to be highly complex to meet the requirements. Due to the increasing number of variants in production processes, as well as shorter innovation and product life cycles, assistance systems should improve quality and reduce complexity of assembly processes. However, many large kitchen manufacturers still assemble kitchen cabinets manually, due to the high variety of components, such as rails and fittings. This paper focuses on the analysis and evaluation of virtual assistance systems to improve quality and usability in individualised kitchen cabinet assembly processes at a large German manufacturer. A solution is identified and detailed.
基金supported by the National Natural Science Foundation of China(Grant11372311)the grant from the State key Laboratory of Astronautic Dynamics(2014-ADL-DW0201)
文摘In the 6th edition of the Chinese Space Trajectory Design Competition held in 2014, a near-Earth asteroid sample-return trajectory design problem was released, in which the motion of the spacecraft is modeled in multi-body dynamics, considering the gravitational forces of the Sun, Earth, and Moon. It is proposed that an electric-propulsion spacecraft initially parking in a circular 200-kin-altitude low Earth orbit is expected to rendezvous with an asteroid and carry as much sample as possible back to the Earth in a 10-year time frame. The team from the Technology and Engineering Center for Space Utilization, Chinese Academy of Sciences has reported a solution with an asteroid sample mass of 328 tons, which is ranked first in the competition. In this article, we will present our design and optimization methods, primarily including overall analysis, target selection, escape from and capture by the Earth-Moon system, and optimization of impulsive and low-thrust trajectories that are modeled in multi-body dynamics. The orbital resonance concept and lunar gravity assists are considered key techniques employed for trajectory design. The reported solution, preliminarily revealing the feasibility of returning a hundreds-of-tons asteroid or asteroid sample, envisions future space missions relating to near-Earth asteroid exploration.
文摘Asteroid exploration is one of the most sophisticated missions currently being investigated. Gravity-assist trajectories have proven valuable in interplanetary missions such as the Pioneer, Voyager and Galileo. In this paper, we design interplanetary trajectory for main belt asteroid exploration mission with the Mars gravity-assist (MGA) using “pork chop” plots and patched-conic theory and give some initial valuable trajectory parameters on main belt asteroid exploration mission with MGA.