We are very pleased to announce that we have invited Dr. Xue-Long JIANG to serve as the Associate Editor-in-Chief for Zoological Research (ZR), effective from 1 March, 2016. Dr. JIANG, Professor and principle invest...We are very pleased to announce that we have invited Dr. Xue-Long JIANG to serve as the Associate Editor-in-Chief for Zoological Research (ZR), effective from 1 March, 2016. Dr. JIANG, Professor and principle investigator from the Laboratory of Mammal Ecology and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, has worked with ZR since 2006 as a member of the editorial board and has played an active and important role in maintaining ZR as a respected academic publishing platform. Currently, he also works as the Associate Editor-in-Chief of Acta Thefiologica Sinica, Mammal Research and as a senior editorial board member of Biodiversity Science.展开更多
We are very pleased to announce that we have invited Dr. Wai-Yee Chan, Professor and Director of School of Biomedical Sciences, The Chinese University of Hong Kong, to serve as the Associate Editor- in-Chief for Zoolo...We are very pleased to announce that we have invited Dr. Wai-Yee Chan, Professor and Director of School of Biomedical Sciences, The Chinese University of Hong Kong, to serve as the Associate Editor- in-Chief for Zoological Research (ZR), effective 1 September, 2016.展开更多
Human fights has always been a concept that evolves with the development of globalization. To clarify their relations, Human Rights made an interview with Xu Tiebing, an associate researcher on international studies w...Human fights has always been a concept that evolves with the development of globalization. To clarify their relations, Human Rights made an interview with Xu Tiebing, an associate researcher on international studies with the Communication University of China. Xu has recently translated the French book Atlas de la Mondialisation into Chinese.展开更多
BACKGROUND High venous ammonia(VA)values have been proven to be a part of the mechanism of hepatic encephalopathy in patients with liver cirrhosis(LC)as well as acute hepatitis.Moreover,VA has been associated with poo...BACKGROUND High venous ammonia(VA)values have been proven to be a part of the mechanism of hepatic encephalopathy in patients with liver cirrhosis(LC)as well as acute hepatitis.Moreover,VA has been associated with poor prognosis and high mortality in these clinical settings.However,the role of ammonia in acuteon-chronic liver failure(ACLF)has not yet been clearly established.AIM To assess the role of VA in predicting the outcome of cirrhotic patients with ACLF in a tertiary care center.METHODS We performed a retrospective observational study including consecutive patients with LC hospitalized for acute non-elective indications such as ascites,hepatic encephalopathy(HE),upper gastrointestinal bleeding,or bacterial infections that fulfilled the Asian Pacific Association for the Study of the Liver(APASL)criteria for ACLF.The study was conducted in“St.Spiridon”University Hospital,Iasi,Romania,a tertiary care center,between January 2017 and January 2019.The APASL ACLF Research Consortium(AARC)score was calculated and ACLF grade was established accordingly.West-haven classification was used for HE.Statistical analysis was performed using IBM SPSS version 22.0.RESULTS Four hundred and forty-six patients were included,aged 59(50-65)years,57.4%men.Child-Pugh,model for end-stage liver disease(MELD)and AARC scores were 11(10-12),19.13±6.79,and 7(6-8),respectively.66.4%had ACLF grade I,31.2%ACLF grade II,and 2.5%ACLF grade III.HE was diagnosed in 83.9%,34%grade I,37.2%grade II,23.5%grade III,and 5.3%grade IV.Overall mortality was 7.8%.VA was 103(78-148)μmol/L.Receiver operating characteristic analysis showed good accuracy for the prediction of in-hospital mortality for the AARC score[Area under the curve(AUC)=0.886],MELD score(AUC=0.816),VA(AUC=0.812)and a fair accuracy for the Child-Pugh score(AUC=0.799).Subsequently,a cut-off value for the prediction of mortality was identified for VA(152.5μmol/L,sensitivity=0.706,1-specificity=0.190).Univariate analysis found acute kidney injury,severe HE(grade III or IV),VA≥152.5μmol/L,MELD score≥22.5,Child-Pugh score≥12.5,and AARC score≥8.5 to be associated with inhospital mortality.Multivariate analysis identified AARC score≥8.5 and venous ammonia≥152μmol/L to be independent predictors of in-hospital mortality.CONCLUSION VA could be used as an inexpensive predictor of in-hospital mortality in patients with ACLF.Patients with both ACLF and VA>152.5μmol/L have a high risk for a poor outcome.展开更多
Document Of World Medical AssociationWorld medical association declaration of Helsinki Ethical principles for medical research involving human subjects
THE number of nongovernmental women’s organizations in China has increased dramatically in recent years. The long list includes friendship organizations of women in the same trade and a number of academic research as...THE number of nongovernmental women’s organizations in China has increased dramatically in recent years. The long list includes friendship organizations of women in the same trade and a number of academic research associations. The Working Committee on Female Professionals, under China Personnel Research Association represents on the major national academic women’s societies. The association’s goal is to study problems confronting female professional women, establishing展开更多
文摘We are very pleased to announce that we have invited Dr. Xue-Long JIANG to serve as the Associate Editor-in-Chief for Zoological Research (ZR), effective from 1 March, 2016. Dr. JIANG, Professor and principle investigator from the Laboratory of Mammal Ecology and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, has worked with ZR since 2006 as a member of the editorial board and has played an active and important role in maintaining ZR as a respected academic publishing platform. Currently, he also works as the Associate Editor-in-Chief of Acta Thefiologica Sinica, Mammal Research and as a senior editorial board member of Biodiversity Science.
文摘We are very pleased to announce that we have invited Dr. Wai-Yee Chan, Professor and Director of School of Biomedical Sciences, The Chinese University of Hong Kong, to serve as the Associate Editor- in-Chief for Zoological Research (ZR), effective 1 September, 2016.
文摘Human fights has always been a concept that evolves with the development of globalization. To clarify their relations, Human Rights made an interview with Xu Tiebing, an associate researcher on international studies with the Communication University of China. Xu has recently translated the French book Atlas de la Mondialisation into Chinese.
文摘BACKGROUND High venous ammonia(VA)values have been proven to be a part of the mechanism of hepatic encephalopathy in patients with liver cirrhosis(LC)as well as acute hepatitis.Moreover,VA has been associated with poor prognosis and high mortality in these clinical settings.However,the role of ammonia in acuteon-chronic liver failure(ACLF)has not yet been clearly established.AIM To assess the role of VA in predicting the outcome of cirrhotic patients with ACLF in a tertiary care center.METHODS We performed a retrospective observational study including consecutive patients with LC hospitalized for acute non-elective indications such as ascites,hepatic encephalopathy(HE),upper gastrointestinal bleeding,or bacterial infections that fulfilled the Asian Pacific Association for the Study of the Liver(APASL)criteria for ACLF.The study was conducted in“St.Spiridon”University Hospital,Iasi,Romania,a tertiary care center,between January 2017 and January 2019.The APASL ACLF Research Consortium(AARC)score was calculated and ACLF grade was established accordingly.West-haven classification was used for HE.Statistical analysis was performed using IBM SPSS version 22.0.RESULTS Four hundred and forty-six patients were included,aged 59(50-65)years,57.4%men.Child-Pugh,model for end-stage liver disease(MELD)and AARC scores were 11(10-12),19.13±6.79,and 7(6-8),respectively.66.4%had ACLF grade I,31.2%ACLF grade II,and 2.5%ACLF grade III.HE was diagnosed in 83.9%,34%grade I,37.2%grade II,23.5%grade III,and 5.3%grade IV.Overall mortality was 7.8%.VA was 103(78-148)μmol/L.Receiver operating characteristic analysis showed good accuracy for the prediction of in-hospital mortality for the AARC score[Area under the curve(AUC)=0.886],MELD score(AUC=0.816),VA(AUC=0.812)and a fair accuracy for the Child-Pugh score(AUC=0.799).Subsequently,a cut-off value for the prediction of mortality was identified for VA(152.5μmol/L,sensitivity=0.706,1-specificity=0.190).Univariate analysis found acute kidney injury,severe HE(grade III or IV),VA≥152.5μmol/L,MELD score≥22.5,Child-Pugh score≥12.5,and AARC score≥8.5 to be associated with inhospital mortality.Multivariate analysis identified AARC score≥8.5 and venous ammonia≥152μmol/L to be independent predictors of in-hospital mortality.CONCLUSION VA could be used as an inexpensive predictor of in-hospital mortality in patients with ACLF.Patients with both ACLF and VA>152.5μmol/L have a high risk for a poor outcome.
文摘Document Of World Medical AssociationWorld medical association declaration of Helsinki Ethical principles for medical research involving human subjects
文摘THE number of nongovernmental women’s organizations in China has increased dramatically in recent years. The long list includes friendship organizations of women in the same trade and a number of academic research associations. The Working Committee on Female Professionals, under China Personnel Research Association represents on the major national academic women’s societies. The association’s goal is to study problems confronting female professional women, establishing