Background and objective: Occupational asthma is responsible for 5 to 20% of adult asthma cases globally, and car painters are among the most at-risk workers. The objective of this study was to determine the prevalenc...Background and objective: Occupational asthma is responsible for 5 to 20% of adult asthma cases globally, and car painters are among the most at-risk workers. The objective of this study was to determine the prevalence and characteristics of car painters with probable occupational asthma in Parakou, Benin. Materials and methods: A prospective cross-sectional study was carried out between April and September 2023 in Parakou, the third most important city in Benin. Results: Overall, 116 workers in 22 car painting shops were included, 64 (55.17%) masters and 52 (44.83%) apprentices. Their mean age was 30.59 (±11.30) years, and their male-female ratio was 28:1. A past history of asthma was reported in 3 (2.59%). There were 113 (97.41%) who used gun spray;49 (42.24%) worked in a confined environment;100 (86.21%) reported breathing discomfort during painting;and 2 (1.72%) used air-filtered masks. The overall prevalence of probable occupational asthma was 10.34% (12/116;95% CI, 6.02 - 17.21), 12.50% (8/64) in masters and 7.69% (4/52) in apprentices (p = 0.398). Preceding occupational rhinitis occurred in 6 (50%). Asthma symptoms were partially controlled in 8 (66.67%) and uncontrolled in one (8.33%). Being a daily smoker (aOR = 4.59;95%CI, 1.01 - 22.00;p = 0.048) was associated with probable occupational asthma, after adjustment for age and permanent residence. Following Peak Expiratory Flow monitoring, four painters provided interpretable records, of whom three were confirmed with occupational asthma based on the Oasys scoring system. Of the 12 with probable occupational asthma, none was followed-up at occupational health departments;3 (25%) were prescribed a short-acting β-2-agonist, and no worker was treated with inhaled corticosteroids. These workers considered the impact of the disease on their productivity at work to be moderate. Conclusion: occupational asthma was common among car painters in Parakou. This calls for raising awareness on this condition, and for actions to improve the prevention and management of the disease among professionals.展开更多
目的探讨慢性阻塞性肺疾病急性加重期(acute exacerbation of chronic obstructive pulmonary disease,AECOPD)患者急性生理学与慢性健康状况评分Ⅱ(acute physiology and chronic health evaluationⅡ,APACHEⅡ)及慢性阻塞性肺疾病和...目的探讨慢性阻塞性肺疾病急性加重期(acute exacerbation of chronic obstructive pulmonary disease,AECOPD)患者急性生理学与慢性健康状况评分Ⅱ(acute physiology and chronic health evaluationⅡ,APACHEⅡ)及慢性阻塞性肺疾病和支气管哮喘生理评分(COPD and asthma physiology score,CAPS)与病情严重程度及预后的关系及评估价值。方法回顾性分析2013年1月至2018年11月于北京积水潭医院呼吸与危重症医学科住院治疗的AECOPD患者239例。根据住院期间有无机械通气分为无机械通气组和机械通气组;根据预后分为存活组和死亡组。住院后计算APACHEⅡ评分及CAPS评分。进行两种评分系统的不同组间比较;进行两种评分系统与住院期间需要行机械通气的可能性及疾病转归的相关性分析;评估入院时两种评分系统对住院期间需要行机械通气的可能性及死亡发生风险的预测价值。结果①AECOPD无机械通气组患者两种评分均明显低于机械通气组[APACHEⅡ分别为(12.09±3.48)分、(18.74±4.06)分,CAPS分别为(18.70±5.70)分、(26.35±7.87)分,P<0.05];②AECOPD存活组患者两种评分均明显低于死亡组[APACHEⅡ分别为(13.88±4.06)分、(20.86±4.43)分,CAPS分别为(19.66±5.37)分、(32.84±6.74)分,P<0.05];③Spearman相关分析显示,AECOPD患者APACHEⅡ评分、CAPS评分与住院期间需要行机械通气的可能性均呈显著相关(r值分别为0.694、0.525,P<0.05);④Spearman相关分析显示,AECOPD患者APACHEⅡ评分、CAPS评分与死亡发生风险均呈显著相关(r值分别为0.554、0.612,P<0.05)。结论AECOPD患者入院时APACHEⅡ评分及CAPS评分与病情严重程度及预后密切相关;对于评估患者病情严重程度、住院期间需要行机械通气的可能性,APACHEⅡ评分优于CAPS评分;两者对于AECOPD患者预后的预测价值基本相当,均具有较高的预测价值。展开更多
哮喘控制测试(Asthma Control Test,ACT)评分作为评估哮喘控制水平调查问卷中的一种,可评估哮喘患者评分时前4周的控制情况,以其简便、快捷、实用等优点受到临床医师及患者的青睐。近年来,随着对ACT评分研究的进一步深入,发现其不仅在...哮喘控制测试(Asthma Control Test,ACT)评分作为评估哮喘控制水平调查问卷中的一种,可评估哮喘患者评分时前4周的控制情况,以其简便、快捷、实用等优点受到临床医师及患者的青睐。近年来,随着对ACT评分研究的进一步深入,发现其不仅在评估哮喘控制水平方面具有重要作用,而且还具有预测哮喘未来风险等功能。本文就ACT评分在哮喘研究中的应用做一综述。展开更多
文摘Background and objective: Occupational asthma is responsible for 5 to 20% of adult asthma cases globally, and car painters are among the most at-risk workers. The objective of this study was to determine the prevalence and characteristics of car painters with probable occupational asthma in Parakou, Benin. Materials and methods: A prospective cross-sectional study was carried out between April and September 2023 in Parakou, the third most important city in Benin. Results: Overall, 116 workers in 22 car painting shops were included, 64 (55.17%) masters and 52 (44.83%) apprentices. Their mean age was 30.59 (±11.30) years, and their male-female ratio was 28:1. A past history of asthma was reported in 3 (2.59%). There were 113 (97.41%) who used gun spray;49 (42.24%) worked in a confined environment;100 (86.21%) reported breathing discomfort during painting;and 2 (1.72%) used air-filtered masks. The overall prevalence of probable occupational asthma was 10.34% (12/116;95% CI, 6.02 - 17.21), 12.50% (8/64) in masters and 7.69% (4/52) in apprentices (p = 0.398). Preceding occupational rhinitis occurred in 6 (50%). Asthma symptoms were partially controlled in 8 (66.67%) and uncontrolled in one (8.33%). Being a daily smoker (aOR = 4.59;95%CI, 1.01 - 22.00;p = 0.048) was associated with probable occupational asthma, after adjustment for age and permanent residence. Following Peak Expiratory Flow monitoring, four painters provided interpretable records, of whom three were confirmed with occupational asthma based on the Oasys scoring system. Of the 12 with probable occupational asthma, none was followed-up at occupational health departments;3 (25%) were prescribed a short-acting β-2-agonist, and no worker was treated with inhaled corticosteroids. These workers considered the impact of the disease on their productivity at work to be moderate. Conclusion: occupational asthma was common among car painters in Parakou. This calls for raising awareness on this condition, and for actions to improve the prevention and management of the disease among professionals.
文摘目的探讨慢性阻塞性肺疾病急性加重期(acute exacerbation of chronic obstructive pulmonary disease,AECOPD)患者急性生理学与慢性健康状况评分Ⅱ(acute physiology and chronic health evaluationⅡ,APACHEⅡ)及慢性阻塞性肺疾病和支气管哮喘生理评分(COPD and asthma physiology score,CAPS)与病情严重程度及预后的关系及评估价值。方法回顾性分析2013年1月至2018年11月于北京积水潭医院呼吸与危重症医学科住院治疗的AECOPD患者239例。根据住院期间有无机械通气分为无机械通气组和机械通气组;根据预后分为存活组和死亡组。住院后计算APACHEⅡ评分及CAPS评分。进行两种评分系统的不同组间比较;进行两种评分系统与住院期间需要行机械通气的可能性及疾病转归的相关性分析;评估入院时两种评分系统对住院期间需要行机械通气的可能性及死亡发生风险的预测价值。结果①AECOPD无机械通气组患者两种评分均明显低于机械通气组[APACHEⅡ分别为(12.09±3.48)分、(18.74±4.06)分,CAPS分别为(18.70±5.70)分、(26.35±7.87)分,P<0.05];②AECOPD存活组患者两种评分均明显低于死亡组[APACHEⅡ分别为(13.88±4.06)分、(20.86±4.43)分,CAPS分别为(19.66±5.37)分、(32.84±6.74)分,P<0.05];③Spearman相关分析显示,AECOPD患者APACHEⅡ评分、CAPS评分与住院期间需要行机械通气的可能性均呈显著相关(r值分别为0.694、0.525,P<0.05);④Spearman相关分析显示,AECOPD患者APACHEⅡ评分、CAPS评分与死亡发生风险均呈显著相关(r值分别为0.554、0.612,P<0.05)。结论AECOPD患者入院时APACHEⅡ评分及CAPS评分与病情严重程度及预后密切相关;对于评估患者病情严重程度、住院期间需要行机械通气的可能性,APACHEⅡ评分优于CAPS评分;两者对于AECOPD患者预后的预测价值基本相当,均具有较高的预测价值。
文摘哮喘控制测试(Asthma Control Test,ACT)评分作为评估哮喘控制水平调查问卷中的一种,可评估哮喘患者评分时前4周的控制情况,以其简便、快捷、实用等优点受到临床医师及患者的青睐。近年来,随着对ACT评分研究的进一步深入,发现其不仅在评估哮喘控制水平方面具有重要作用,而且还具有预测哮喘未来风险等功能。本文就ACT评分在哮喘研究中的应用做一综述。
