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Astragalus granule combined with auricular point sticking for cough varlant asthma in children 被引量:1
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作者 张黎雯 《China Medical Abstracts(Internal Medicine)》 2017年第1期6-7,共2页
Objective To observe the clinical efficacy and effect of Astragalus Granule(AG),auricular point sticking combined with aerosol inhalation on the levels of tumor necrosis factor-α(TNF-α),interleukin-4(IL-4),interleuk... Objective To observe the clinical efficacy and effect of Astragalus Granule(AG),auricular point sticking combined with aerosol inhalation on the levels of tumor necrosis factor-α(TNF-α),interleukin-4(IL-4),interleukin-10(IL-10),eosinophil cell count(EOS),and immunoglobulin E(lgE)in cough variant asthma(CVA) 展开更多
关键词 TNF IL CVA EOS astragalus granule combined with auricular point sticking for cough varlant asthma in children
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Astragalus Salvia Granules to Benefit the Qi (Qishen Yiqi Keli) protects H9C2 cardiomyocytes by suppressing oxidative stress
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作者 Bangze Fu Shuzhen Guo +2 位作者 Xue Yu Hong Chang Wei Wang 《Journal of Traditional Chinese Medical Sciences》 2016年第3期176-183,共8页
Objective:To investigate the effects of Qishen Yiqi Keli(QSYQ;Astragalus Salvia Granules to Benefit the Qi)on ROS scavenging and inhibition of NADPH oxidase in an effort to identify new natural antioxidants.Methods:A ... Objective:To investigate the effects of Qishen Yiqi Keli(QSYQ;Astragalus Salvia Granules to Benefit the Qi)on ROS scavenging and inhibition of NADPH oxidase in an effort to identify new natural antioxidants.Methods:A total of 23 representative components in QSYQ were investigated,their effects on hydrogen peroxide induced ROS were assayed by dichlorofluorescein assay.Lucigenin chemiluminescence was adopted to test the effect on NADPH oxidase activity in H9C2 cardiomyocyte cells,and pyrogallol autoxidation was adopted to test the superoxide scavenging capacity.Results:Nine compounds in QSYQ could significantly inhibited H2O2-induced ROS increase compared with the model group(P<.05),including tanshinone I,salvianolic acid A,danshinone IIA,and cryptotanshinone from salvia root,luteolin from salvia root,harpagoside,harpagide,and angoroside C from scrophularia root.Nine compounds in QSYQ could significantly inhibited the production ofO2in H9C2 cell.Tanshinone I showed a lowest IC50 value 0.07 mM,the other including salvianolic acid A,cryptotanshinone,and salvianolic acid B,luteolin,isochlorogenic acid C,astragaloside IV,and glycyrrhetinic acid.Licochalcone A inhibited the autoxidation of pyrogallol at a low concentration,and tanshinone I showed no significant inhibitory effect from 2 mM to 20 mM.Conclusion:QSYQ had significant effects on ROS scavenging and inhibition of NADPH oxidase.Tanshinone I and salvianolic acid A are potential NADPH oxidase inhibitors. 展开更多
关键词 Qishen Yiqi Keli QSYQ astragalus Salvia granules to Benefit the Qi NADPH oxidase Tanshinone I
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