Astrocytes are key cells in the central nervous system.They are involved in many important functions under physiological and pathological conditions.As part of neuroglia,they have been recognised as cellular elements ...Astrocytes are key cells in the central nervous system.They are involved in many important functions under physiological and pathological conditions.As part of neuroglia,they have been recognised as cellular elements in their own right.The name astrocyte was first proposed by Mihaly von Lenhossek in 1895 because of the finely branched processes and star-like appearance of these particular cells.As early as the late 19th and early 20th centuries,Ramon y Cajal and Camillo Golgi had noted that although astrocytes have stellate features,their morphology is extremely diverse.Modern research has confirmed the morphological diversity of astrocytes both in vitro and in vivo and their complex,specific,and important roles in the central nervous system.In this review,the functions of astrocytes and their roles are described.展开更多
Neurons and glial cells, particularly astrocytes, are the two main cell populations in the central nervous system. While it is established that brain functions primarily rely on neuronal activity, an active contributi...Neurons and glial cells, particularly astrocytes, are the two main cell populations in the central nervous system. While it is established that brain functions primarily rely on neuronal activity, an active contribution of astrocytes to information processing is only starting to be considered. There is growing evidence that astrocytes, as part of the tripartite synapse, participate in this challenge by receiving and integrating neuronal signals and, in turn, by sending signals that target neurons[1]. The involvement of astrocytes in information processing has mainly been studied at the level of the single astrocyte, often missing the role of astrocyte networks in this process.展开更多
文摘Astrocytes are key cells in the central nervous system.They are involved in many important functions under physiological and pathological conditions.As part of neuroglia,they have been recognised as cellular elements in their own right.The name astrocyte was first proposed by Mihaly von Lenhossek in 1895 because of the finely branched processes and star-like appearance of these particular cells.As early as the late 19th and early 20th centuries,Ramon y Cajal and Camillo Golgi had noted that although astrocytes have stellate features,their morphology is extremely diverse.Modern research has confirmed the morphological diversity of astrocytes both in vitro and in vivo and their complex,specific,and important roles in the central nervous system.In this review,the functions of astrocytes and their roles are described.
文摘Neurons and glial cells, particularly astrocytes, are the two main cell populations in the central nervous system. While it is established that brain functions primarily rely on neuronal activity, an active contribution of astrocytes to information processing is only starting to be considered. There is growing evidence that astrocytes, as part of the tripartite synapse, participate in this challenge by receiving and integrating neuronal signals and, in turn, by sending signals that target neurons[1]. The involvement of astrocytes in information processing has mainly been studied at the level of the single astrocyte, often missing the role of astrocyte networks in this process.
