BACKGROUND Since 2017,the number of magnet ingestion cases has increased year over year in our hospital.Almost all of the ingested magnetic foreign bodies were magnetic beads,and most of the patients experienced intes...BACKGROUND Since 2017,the number of magnet ingestion cases has increased year over year in our hospital.Almost all of the ingested magnetic foreign bodies were magnetic beads,and most of the patients experienced intestinal perforations,causing substantial damage.AIM To summarize our experience with surgical treatment of multiple magnet ingestion in children.METHODS The data for general surgeries were collected from January 2010 to April 2020,and the clinical characteristics,treatment methods,and outcomes were summarized and analyzed.Several typical cases were selected and discussed.RESULTS Fifty-six cases of ingested magnetic foreign bodies were collected,of which 47 were magnetic beads.The average patient age was 4.7±3.0 years old.The number of ingested magnetic foreign bodies ranged from 2 to 73.There were 26 cases with symptoms at the time of admission,including two cases of shock.Thirteen patients were discharged successfully following conservative treatment and 43 were treated by surgery.Laparotomy was the main method of operation.Laparoscopy was used in four cases,of which three were converted to open surgery,and one was treated successfully using surgery through the navel.Postoperative complications occurred in seven cases,incision infections were observed in six,and adhesive ileus was observed in one.CONCLUSION Clinicians need to summarize their experiences with treating magnetic foreign body ingestions in detail and carry out clinical research to reduce the damage to children.展开更多
Nanocluster polyoxometalates with a structure of buckyball (fullerene) are a promising means of targeted delivery of drugs in the body. In this paper, based on an analysis of histological sections of liver and kidney ...Nanocluster polyoxometalates with a structure of buckyball (fullerene) are a promising means of targeted delivery of drugs in the body. In this paper, based on an analysis of histological sections of liver and kidney and peripheral blood, showed a significant reduction of toxicity of buckyballs, containing ions of molybdenum (VI), the substitution of Mo (V) ions to Fe (III), in contrast to buckyballs based on Mo (V). The absence of accumulation of molybdenum in rats with a daily intramuscular injection of aqueous solutions of both drugs within a month was confirmed.展开更多
The phenomena of buckyball-graphene collisions were investigated by classical molecular dynamics(MD)simulation using the empirical Tersoff potential.Three cases were investigated:collisions between a buckyball and a s...The phenomena of buckyball-graphene collisions were investigated by classical molecular dynamics(MD)simulation using the empirical Tersoff potential.Three cases were investigated:collisions between a buckyball and a single-layer graphene;collisions between a nano-onion(a double-layer concentric spherical nanostructure:a C_(60) in a C_(320))and a single-layer graphene;collisions between a nano-onion and a double-layer graphene.The impact velocity of the buckyball or nano-onion ranged from 4.37 km/s to 15.31 km/s.Simulation results for the buckyball-graphene collisions show that the buckyball bounces back when the impact velocity is less than 8.75 km/s,sticks to the graphene when the impact velocity is between 8.75 km/s and 12.03 km/s,and breaks when the impact velocity is greater than 12.03 km/s.Similar phenomena are observed for the other two cases.A single buckyball can never go through a single-layer graphene intact;however,the inner structure(C_(60))of a nano-onion can penetrate through a single-layer graphene without any damage.The energy evolution during the whole simulation process was also studied.展开更多
文摘BACKGROUND Since 2017,the number of magnet ingestion cases has increased year over year in our hospital.Almost all of the ingested magnetic foreign bodies were magnetic beads,and most of the patients experienced intestinal perforations,causing substantial damage.AIM To summarize our experience with surgical treatment of multiple magnet ingestion in children.METHODS The data for general surgeries were collected from January 2010 to April 2020,and the clinical characteristics,treatment methods,and outcomes were summarized and analyzed.Several typical cases were selected and discussed.RESULTS Fifty-six cases of ingested magnetic foreign bodies were collected,of which 47 were magnetic beads.The average patient age was 4.7±3.0 years old.The number of ingested magnetic foreign bodies ranged from 2 to 73.There were 26 cases with symptoms at the time of admission,including two cases of shock.Thirteen patients were discharged successfully following conservative treatment and 43 were treated by surgery.Laparotomy was the main method of operation.Laparoscopy was used in four cases,of which three were converted to open surgery,and one was treated successfully using surgery through the navel.Postoperative complications occurred in seven cases,incision infections were observed in six,and adhesive ileus was observed in one.CONCLUSION Clinicians need to summarize their experiences with treating magnetic foreign body ingestions in detail and carry out clinical research to reduce the damage to children.
文摘Nanocluster polyoxometalates with a structure of buckyball (fullerene) are a promising means of targeted delivery of drugs in the body. In this paper, based on an analysis of histological sections of liver and kidney and peripheral blood, showed a significant reduction of toxicity of buckyballs, containing ions of molybdenum (VI), the substitution of Mo (V) ions to Fe (III), in contrast to buckyballs based on Mo (V). The absence of accumulation of molybdenum in rats with a daily intramuscular injection of aqueous solutions of both drugs within a month was confirmed.
文摘The phenomena of buckyball-graphene collisions were investigated by classical molecular dynamics(MD)simulation using the empirical Tersoff potential.Three cases were investigated:collisions between a buckyball and a single-layer graphene;collisions between a nano-onion(a double-layer concentric spherical nanostructure:a C_(60) in a C_(320))and a single-layer graphene;collisions between a nano-onion and a double-layer graphene.The impact velocity of the buckyball or nano-onion ranged from 4.37 km/s to 15.31 km/s.Simulation results for the buckyball-graphene collisions show that the buckyball bounces back when the impact velocity is less than 8.75 km/s,sticks to the graphene when the impact velocity is between 8.75 km/s and 12.03 km/s,and breaks when the impact velocity is greater than 12.03 km/s.Similar phenomena are observed for the other two cases.A single buckyball can never go through a single-layer graphene intact;however,the inner structure(C_(60))of a nano-onion can penetrate through a single-layer graphene without any damage.The energy evolution during the whole simulation process was also studied.
