Chemical investigation on the medicinal fungus Ganoderma australe led to the identification of ten new nor-lanostane triterpenes,namely two hexa-nor ones,ganoaustratetraenones A(1)and B(2),five penta-nor ones,ganoaust...Chemical investigation on the medicinal fungus Ganoderma australe led to the identification of ten new nor-lanostane triterpenes,namely two hexa-nor ones,ganoaustratetraenones A(1)and B(2),five penta-nor ones,ganoaustraldehydes A-E(3-7),and three tetra-nor ones ganoaustrenoic acids A-C(8-10).The chemical structures along with the absolute configurations were determined by extensive spectroscopic analysis of 1D&2D NMR and HRESIMS data.The postulated biosynthesis pathways of these compounds were proposed.Ganoaustraldehydes A(3)and B(4)showed moderate inhibition against nitric oxide production in RAW264.7 macrophage cells with the respec-tive IC_(50) values of 32.5,34.2μM(the IC_(50) of positive control pyrrolidine dithiocarbamate was 20.0μM).展开更多
Temperature is a key factor that shapes the distribution of organisms.Having knowledge about how species respond to temperature is relevant to devise strategies for addressing the impacts of climate change.Aquatic ins...Temperature is a key factor that shapes the distribution of organisms.Having knowledge about how species respond to temperature is relevant to devise strategies for addressing the impacts of climate change.Aquatic insects are particularly vulnerable to climate change,yet there is still much to learn about their ecology and distribution.In the Yungas ecoregion of Northwestern Argentina,cold-and warm-adapted species of the orders Ephemeroptera,Plecoptera,and Trichoptera(EPT)are segregated by elevation.We modeled the ecological niche of South American EPT species in this region using available data and projected their potential distribution in geographic space.Species were grouped based on their ecogeographic similarity,and we analyzed their replacement pattern along elevation gradients,focusing on the ecotone where opposing thermal preferences converge.Along this interface,we identified critical points where the combined incidence of cold and warm assemblages maximizes,indicating a significant transition zone.We found that the Montane Cloud Forest holds the interface,with a particularly greater suitability at its lower boundary.The main axis of the interface runs in a N-S direction and falls between 14°C-16°C mean annual isotherms.The probability of a particular location within a basin being classified as part of the interface increases as Kira’s warmth index approaches a score around 150.Understanding the interface is critical for defining the thermal limits of species distribution and designing biomonitoring programs.Changes in the location of thermal constants related to mountainous ecotones may cause vertical displacement of aquatic insects and vegetation communities.We have recognized significant temperature thresholds that serve as indicators of suitability for the interface.As global warming is anticipated to shift these indicators,we suggest using them to monitor the imprints of climate change on mountain ecosystems.展开更多
Introduction: Due to its severe toxicity, carbon monoxide poisoning is an emergency that leads to cardiac and brain involvement, and emergency physicians should aim to master this diagnosis. This study is intended to ...Introduction: Due to its severe toxicity, carbon monoxide poisoning is an emergency that leads to cardiac and brain involvement, and emergency physicians should aim to master this diagnosis. This study is intended to describe the expected prevalence of these severe toxicities in the emergency department. Materials and Methods: A retrospective cohort of consecutive patients over 16 years of age presenting with carbon monoxide poisoning to the emergency department of the Hospital Universitario Austral, Argentina, during the period from January 2018 to June 2022. The prevalence of myocardial and brain toxicity was assessed regarding percentage, continuous variables with mean and standard deviation, categorical variables with percentage and absolute frequency. Positive findings of acute neurological toxicity included seizures, syncope and coma, while cardiovascular toxicity encompassed acute myocardial infarction (MI) diagnosed by electrocardiogram or elevated troponin levels, arrhythmias, and the development of pulmonary edema/ congestive heart failure (CHF) confirmed by chest X-ray with suggestive signs or clinically compatible symptoms. Patients were followed-up for 90 days to estimate hospitalization and mortality. Results: A total of 67 patients were evaluated;44.77% of them were males with a mean age of 38.5 ± 14.97 years. The prevalence of acute myocardial toxicity was 7.46% (n: 5). Among these patients, 3 had overweight as a risk factor, and 3 showed ECG abnormalities with negative T-waves. The prevalence of acute brain toxicity was 8.9% (n: 6). In total, 37% (n: 25) of patients met the criteria for hyperbaric oxygen therapy, of which 32% (n: 8) underwent more than one session. A total of 7.46% of patients (n: 5) required hospitalization. Mortality at 90 days was 0%. Conclusion: Among the patients who presented to the emergency department, the prevalence of acute myocardial toxicity was 7.46% (n: 5), which is lower than the prevalence reported in other studies to date. The prevalence of acute brain toxicity was 8.9% (n: 6), and there are no studies describing the prevalence of acute brain toxicity in the emergency department to date. There were no fatalities in our series.展开更多
Based on the field data acquired in the program of fast ice observation off Zhongshan Station, Prydz Bay, East Antarctica during the austral summer 2005/ 2006, physical properties evolution of fast ice during the ice ...Based on the field data acquired in the program of fast ice observation off Zhongshan Station, Prydz Bay, East Antarctica during the austral summer 2005/ 2006, physical properties evolution of fast ice during the ice ablation season is analyzed in detail. Results show that the annual maximum ice thickness in 2005 occurred in later November, and then ice started to reek, and the ablation duration was 62 days; sea water under the ice became warmer synchronously; corresponding to the warming sea ice temperature, a "relative cold mid-layer" appeared in sea ice; the fast ice marginal line recoiled back to the shore observably, and the recoil distance was 20.9 km from 18 December 2005 through 14 January 2006. In addition, based on the data of sea ice thickness survey along the investigation course of MV Xuelong on December 18 of 2005, the ice thickness distribution paten in the marginal ice zone have been described : sea ice thickness increased, but the diversity of floe ice thick-ness decreased from open water to fast ice zone distinctly.展开更多
The relationships of variations of sea surface temperature anomalies (SSTA) in the South Pacificwith ENSO and Southern Hemisphere Annular Mode (SAM) are examined in the present article byemploying the NCEP-NCAR reanal...The relationships of variations of sea surface temperature anomalies (SSTA) in the South Pacificwith ENSO and Southern Hemisphere Annular Mode (SAM) are examined in the present article byemploying the NCEP-NCAR reanalysis from 1951 to 2006. Two principal modes of South Pacific SSTA areobtained using the EOF (Empirical Orthogonal Function) analysis for austral winter (June, July and August).Our results suggest that EOF1 is closely related with ENSO and EOF2 links to SAM. The EOF1 varieslargely on an interannual and EOF2 on a decadal scale. The time series of coefficients of EOF1 is highlycorrelated simultaneously with Nino3 index. However, the time series of coefficients of EOF2 issignificantly correlated with the March-April-May mean SAM index. Both the EOF1 and EOF2 are found insignificant correlation to summer precipitation over China. With higher-than-normal SSTs in the easternSouth Pacific and simultaneously lower SSTs in the western South Pacific in June-July-August, thesummertime rainfall is found to be less than normal in northern China. As displayed in EOF2 of SSTA, inyears with lower-than-normal SSTs in mid-latitude southern and equatorial eastern Pacific andhigher-than-normal SSTs in the equatorial middle Pacific in March-April-May, the summer precipitation inAugust tends to be more than normal in regions south of Yangtze River.展开更多
This paper documents a decadal strengthened co-variability of the Antarctic Oscillation (AAO) and ENSO in austral spring after the mid-1990s. During the period 1979-93, the ENSO (AAO) spatial signatures are restri...This paper documents a decadal strengthened co-variability of the Antarctic Oscillation (AAO) and ENSO in austral spring after the mid-1990s. During the period 1979-93, the ENSO (AAO) spatial signatures are restricted to the tropicsmidlatitudes (Antarctic-midlatitudes) of the Southern Hemisphere (SH), with a weak connection between the two oscillations. Comparatively, after the mid-1990s, the E1 Nifio-related atmospheric anomalies project on a negative AAO pattern with a barotropic structure in the mid-high latitudes of the SH. The expansion of E1 Nifio-related air temperature anomalies have a heightened impact on the meridional thermal structure of the SH, contributing to a weakened circumpolar westerly and strengthened subtropical jet. Meanwhile, the ENSO-related southern three-cell circulations expand poleward and then strongly couple the Antarctic and the tropics. Numerical simulation results suggest that the intensified connection between ENSO and SST in the South Pacific since the mid-1990s is responsible for the strengthened AAO-ENSO relationship.展开更多
Surface ozone(O3)is a secondary pollutant harmful to human health and a greenhouse gas which is one of the prime climate forcers.Due to the clean atmospheric environment of the Antarctic region and given the complexit...Surface ozone(O3)is a secondary pollutant harmful to human health and a greenhouse gas which is one of the prime climate forcers.Due to the clean atmospheric environment of the Antarctic region and given the complexity of O3 chemistry,the observation of surface O3 variability in this region is necessary in the quest to better understand the potential sources and sink of polar surface O3.In this paper,we highlighted our observations on O3 variability at the Great Wall Station(GWS)during austral summer in December 2018 and January 2019.The continuous surface O3 measurement at the GWS,Antarctica was carried out using the Ecotech Ozone analyzer.To understand the roles of the meteorological conditions on the temporal variations of O3,meteorological data was obtained from the conventional auto-observational station at the GWS.The Hybrid Single-Particle Lagrangian Integrated Trajectory(HYSPLIT)model was employed to investigate the air mass transport over the region.The observed austral summer surface O3 concentrations at the GWS exhibited variability and were significantly lower than those previously observed at other permanent coastal stations in Antarctica.The surface ozone variability at the GWS was strongly influenced by the synoptic change of air mass origin although the roles of photochemistry production and destruction were still uncertain.Marine characteristics and stable surface O3 characterized the air masses that reached the GWS.The unique characteristic of surface O3 at the coastal site of GWS was emphasized by its synoptic air mass characteristics,which displayed a significant influence on surface O3 variability.Air mass that traveled over the ocean with relatively shorter distance was linked to the lower O3 level,whereby the marine transport of reactive bromine(Br)species was thought to play a significant role in the tropospheric chemistry that leads to O3 destruction.Meanwhile,the diurnal variation indicated that the O3 background concentration levels were not strongly associated with the local atmospheric conditions.展开更多
-STD Data obtained from the Third Chinese National Antarctic Research Expedition from January to February 1987 in the region near the South Shetland Islands are used to investigate an oceanic front, continental water ...-STD Data obtained from the Third Chinese National Antarctic Research Expedition from January to February 1987 in the region near the South Shetland Islands are used to investigate an oceanic front, continental water boundary (CWB), north of the South Shetland Islands. The characteristics of the CWB in surface and subsurface layers as well as deep layer are discussed respectively. The estimations of the geostrophic currents and the baroclinic deformed radius Rbc in this area show that the flow along the front is in the geostrophic equilibrium approximately, and the formation of the front is mainly due to the strong boundary current north of the South Shetland Islands. Its length along the front is estimated to be about 360 km and its width across the front is about 30 km.展开更多
Have you ever seen this kind of unique animal,which is cute,a round ball of fluff with sharp claws and a big nose in Australia? The answer is koala found only in small fragmented habitats on the eastern coast of Austr...Have you ever seen this kind of unique animal,which is cute,a round ball of fluff with sharp claws and a big nose in Australia? The answer is koala found only in small fragmented habitats on the eastern coast of Australia. It was a sunny day.We had chance to go to the Lone Pine Koala Sanctuary in Queensland,the world’s first and largest koala sanctuary.I did not realize that until I saw the first batch of koalas there.It was amazing to watch over 130"drunk"koalas in one place.展开更多
基金National Natural Science Foundation of China (grant numbers 21961142008,22177138) for fundings.
文摘Chemical investigation on the medicinal fungus Ganoderma australe led to the identification of ten new nor-lanostane triterpenes,namely two hexa-nor ones,ganoaustratetraenones A(1)and B(2),five penta-nor ones,ganoaustraldehydes A-E(3-7),and three tetra-nor ones ganoaustrenoic acids A-C(8-10).The chemical structures along with the absolute configurations were determined by extensive spectroscopic analysis of 1D&2D NMR and HRESIMS data.The postulated biosynthesis pathways of these compounds were proposed.Ganoaustraldehydes A(3)and B(4)showed moderate inhibition against nitric oxide production in RAW264.7 macrophage cells with the respec-tive IC_(50) values of 32.5,34.2μM(the IC_(50) of positive control pyrrolidine dithiocarbamate was 20.0μM).
文摘Temperature is a key factor that shapes the distribution of organisms.Having knowledge about how species respond to temperature is relevant to devise strategies for addressing the impacts of climate change.Aquatic insects are particularly vulnerable to climate change,yet there is still much to learn about their ecology and distribution.In the Yungas ecoregion of Northwestern Argentina,cold-and warm-adapted species of the orders Ephemeroptera,Plecoptera,and Trichoptera(EPT)are segregated by elevation.We modeled the ecological niche of South American EPT species in this region using available data and projected their potential distribution in geographic space.Species were grouped based on their ecogeographic similarity,and we analyzed their replacement pattern along elevation gradients,focusing on the ecotone where opposing thermal preferences converge.Along this interface,we identified critical points where the combined incidence of cold and warm assemblages maximizes,indicating a significant transition zone.We found that the Montane Cloud Forest holds the interface,with a particularly greater suitability at its lower boundary.The main axis of the interface runs in a N-S direction and falls between 14°C-16°C mean annual isotherms.The probability of a particular location within a basin being classified as part of the interface increases as Kira’s warmth index approaches a score around 150.Understanding the interface is critical for defining the thermal limits of species distribution and designing biomonitoring programs.Changes in the location of thermal constants related to mountainous ecotones may cause vertical displacement of aquatic insects and vegetation communities.We have recognized significant temperature thresholds that serve as indicators of suitability for the interface.As global warming is anticipated to shift these indicators,we suggest using them to monitor the imprints of climate change on mountain ecosystems.
文摘Introduction: Due to its severe toxicity, carbon monoxide poisoning is an emergency that leads to cardiac and brain involvement, and emergency physicians should aim to master this diagnosis. This study is intended to describe the expected prevalence of these severe toxicities in the emergency department. Materials and Methods: A retrospective cohort of consecutive patients over 16 years of age presenting with carbon monoxide poisoning to the emergency department of the Hospital Universitario Austral, Argentina, during the period from January 2018 to June 2022. The prevalence of myocardial and brain toxicity was assessed regarding percentage, continuous variables with mean and standard deviation, categorical variables with percentage and absolute frequency. Positive findings of acute neurological toxicity included seizures, syncope and coma, while cardiovascular toxicity encompassed acute myocardial infarction (MI) diagnosed by electrocardiogram or elevated troponin levels, arrhythmias, and the development of pulmonary edema/ congestive heart failure (CHF) confirmed by chest X-ray with suggestive signs or clinically compatible symptoms. Patients were followed-up for 90 days to estimate hospitalization and mortality. Results: A total of 67 patients were evaluated;44.77% of them were males with a mean age of 38.5 ± 14.97 years. The prevalence of acute myocardial toxicity was 7.46% (n: 5). Among these patients, 3 had overweight as a risk factor, and 3 showed ECG abnormalities with negative T-waves. The prevalence of acute brain toxicity was 8.9% (n: 6). In total, 37% (n: 25) of patients met the criteria for hyperbaric oxygen therapy, of which 32% (n: 8) underwent more than one session. A total of 7.46% of patients (n: 5) required hospitalization. Mortality at 90 days was 0%. Conclusion: Among the patients who presented to the emergency department, the prevalence of acute myocardial toxicity was 7.46% (n: 5), which is lower than the prevalence reported in other studies to date. The prevalence of acute brain toxicity was 8.9% (n: 6), and there are no studies describing the prevalence of acute brain toxicity in the emergency department to date. There were no fatalities in our series.
基金supported by the National Natural Science Foundation of China under contract No.40676001 No.40233032,the National Key Technology R&D Program No.2006BAB18B03.
文摘Based on the field data acquired in the program of fast ice observation off Zhongshan Station, Prydz Bay, East Antarctica during the austral summer 2005/ 2006, physical properties evolution of fast ice during the ice ablation season is analyzed in detail. Results show that the annual maximum ice thickness in 2005 occurred in later November, and then ice started to reek, and the ablation duration was 62 days; sea water under the ice became warmer synchronously; corresponding to the warming sea ice temperature, a "relative cold mid-layer" appeared in sea ice; the fast ice marginal line recoiled back to the shore observably, and the recoil distance was 20.9 km from 18 December 2005 through 14 January 2006. In addition, based on the data of sea ice thickness survey along the investigation course of MV Xuelong on December 18 of 2005, the ice thickness distribution paten in the marginal ice zone have been described : sea ice thickness increased, but the diversity of floe ice thick-ness decreased from open water to fast ice zone distinctly.
基金Natural Science Foundation of China(41105056,41175062)"Qinglan"Project of Jiangsu Province for Activating Research TeamsPriority Academic Program Development of Jiangsu Province Higher Education Institutions
文摘The relationships of variations of sea surface temperature anomalies (SSTA) in the South Pacificwith ENSO and Southern Hemisphere Annular Mode (SAM) are examined in the present article byemploying the NCEP-NCAR reanalysis from 1951 to 2006. Two principal modes of South Pacific SSTA areobtained using the EOF (Empirical Orthogonal Function) analysis for austral winter (June, July and August).Our results suggest that EOF1 is closely related with ENSO and EOF2 links to SAM. The EOF1 varieslargely on an interannual and EOF2 on a decadal scale. The time series of coefficients of EOF1 is highlycorrelated simultaneously with Nino3 index. However, the time series of coefficients of EOF2 issignificantly correlated with the March-April-May mean SAM index. Both the EOF1 and EOF2 are found insignificant correlation to summer precipitation over China. With higher-than-normal SSTs in the easternSouth Pacific and simultaneously lower SSTs in the western South Pacific in June-July-August, thesummertime rainfall is found to be less than normal in northern China. As displayed in EOF2 of SSTA, inyears with lower-than-normal SSTs in mid-latitude southern and equatorial eastern Pacific andhigher-than-normal SSTs in the equatorial middle Pacific in March-April-May, the summer precipitation inAugust tends to be more than normal in regions south of Yangtze River.
基金jointly supported by the National Natural Science Foundation of China(Grant Nos.41421004 and 41210007)the Special Fund for Public Welfare Industry(Meteorology)(Grant No.GYHY201306026)
文摘This paper documents a decadal strengthened co-variability of the Antarctic Oscillation (AAO) and ENSO in austral spring after the mid-1990s. During the period 1979-93, the ENSO (AAO) spatial signatures are restricted to the tropicsmidlatitudes (Antarctic-midlatitudes) of the Southern Hemisphere (SH), with a weak connection between the two oscillations. Comparatively, after the mid-1990s, the E1 Nifio-related atmospheric anomalies project on a negative AAO pattern with a barotropic structure in the mid-high latitudes of the SH. The expansion of E1 Nifio-related air temperature anomalies have a heightened impact on the meridional thermal structure of the SH, contributing to a weakened circumpolar westerly and strengthened subtropical jet. Meanwhile, the ENSO-related southern three-cell circulations expand poleward and then strongly couple the Antarctic and the tropics. Numerical simulation results suggest that the intensified connection between ENSO and SST in the South Pacific since the mid-1990s is responsible for the strengthened AAO-ENSO relationship.
基金funded by the Sultan Mizan Antarctic Research Foundation(YPASM,2017)Malaysiasupported by the Chinese Arctic and Antarctic Administration(CAA)support by Universiti Malaysia Sabah(UMS)。
文摘Surface ozone(O3)is a secondary pollutant harmful to human health and a greenhouse gas which is one of the prime climate forcers.Due to the clean atmospheric environment of the Antarctic region and given the complexity of O3 chemistry,the observation of surface O3 variability in this region is necessary in the quest to better understand the potential sources and sink of polar surface O3.In this paper,we highlighted our observations on O3 variability at the Great Wall Station(GWS)during austral summer in December 2018 and January 2019.The continuous surface O3 measurement at the GWS,Antarctica was carried out using the Ecotech Ozone analyzer.To understand the roles of the meteorological conditions on the temporal variations of O3,meteorological data was obtained from the conventional auto-observational station at the GWS.The Hybrid Single-Particle Lagrangian Integrated Trajectory(HYSPLIT)model was employed to investigate the air mass transport over the region.The observed austral summer surface O3 concentrations at the GWS exhibited variability and were significantly lower than those previously observed at other permanent coastal stations in Antarctica.The surface ozone variability at the GWS was strongly influenced by the synoptic change of air mass origin although the roles of photochemistry production and destruction were still uncertain.Marine characteristics and stable surface O3 characterized the air masses that reached the GWS.The unique characteristic of surface O3 at the coastal site of GWS was emphasized by its synoptic air mass characteristics,which displayed a significant influence on surface O3 variability.Air mass that traveled over the ocean with relatively shorter distance was linked to the lower O3 level,whereby the marine transport of reactive bromine(Br)species was thought to play a significant role in the tropospheric chemistry that leads to O3 destruction.Meanwhile,the diurnal variation indicated that the O3 background concentration levels were not strongly associated with the local atmospheric conditions.
文摘-STD Data obtained from the Third Chinese National Antarctic Research Expedition from January to February 1987 in the region near the South Shetland Islands are used to investigate an oceanic front, continental water boundary (CWB), north of the South Shetland Islands. The characteristics of the CWB in surface and subsurface layers as well as deep layer are discussed respectively. The estimations of the geostrophic currents and the baroclinic deformed radius Rbc in this area show that the flow along the front is in the geostrophic equilibrium approximately, and the formation of the front is mainly due to the strong boundary current north of the South Shetland Islands. Its length along the front is estimated to be about 360 km and its width across the front is about 30 km.
文摘Have you ever seen this kind of unique animal,which is cute,a round ball of fluff with sharp claws and a big nose in Australia? The answer is koala found only in small fragmented habitats on the eastern coast of Australia. It was a sunny day.We had chance to go to the Lone Pine Koala Sanctuary in Queensland,the world’s first and largest koala sanctuary.I did not realize that until I saw the first batch of koalas there.It was amazing to watch over 130"drunk"koalas in one place.