The Internet of Things(IoT)is a smart networking infrastructure of physical devices,i.e.,things,that are embedded with sensors,actuators,software,and other technologies,to connect and share data with the respective se...The Internet of Things(IoT)is a smart networking infrastructure of physical devices,i.e.,things,that are embedded with sensors,actuators,software,and other technologies,to connect and share data with the respective server module.Although IoTs are cornerstones in different application domains,the device’s authenticity,i.e.,of server(s)and ordinary devices,is the most crucial issue and must be resolved on a priority basis.Therefore,various field-proven methodologies were presented to streamline the verification process of the communicating devices;however,location-aware authentication has not been reported as per our knowledge,which is a crucial metric,especially in scenarios where devices are mobile.This paper presents a lightweight and location-aware device-to-server authentication technique where the device’s membership with the nearest server is subjected to its location information along with other measures.Initially,Media Access Control(MAC)address and Advance Encryption Scheme(AES)along with a secret shared key,i.e.,λ_(i) of 128 bits,have been utilized by Trusted Authority(TA)to generate MaskIDs,which are used instead of the original ID,for every device,i.e.,server and member,and are shared in the offline phase.Secondly,TA shares a list of authentic devices,i.e.,server S_(j) and members C_(i),with every device in the IoT for the onward verification process,which is required to be executed before the initialization of the actual communication process.Additionally,every device should be located such that it lies within the coverage area of a server,and this location information is used in the authentication process.A thorough analytical analysis was carried out to check the susceptibility of the proposed and existing authentication approaches against well-known intruder attacks,i.e.,man-in-the-middle,masquerading,device,and server impersonations,etc.,especially in the IoT domain.Moreover,proposed authentication and existing state-of-the-art approaches have been simulated in the real environment of IoT to verify their performance,particularly in terms of various evaluation metrics,i.e.,processing,communication,and storage overheads.These results have verified the superiority of the proposed scheme against existing state-of-the-art approaches,preferably in terms of communication,storage,and processing costs.展开更多
Nowadays, devices are connected across all areas, from intelligent buildings and smart cities to Industry 4.0 andsmart healthcare. With the exponential growth of Internet of Things usage in our world, IoT security is ...Nowadays, devices are connected across all areas, from intelligent buildings and smart cities to Industry 4.0 andsmart healthcare. With the exponential growth of Internet of Things usage in our world, IoT security is still thebiggest challenge for its deployment. The main goal of IoT security is to ensure the accessibility of services providedby an IoT environment, protect privacy, and confidentiality, and guarantee the safety of IoT users, infrastructures,data, and devices. Authentication, as the first line of defense against security threats, becomes the priority ofeveryone. It can either grant or deny users access to resources according to their legitimacy. As a result, studyingand researching authentication issues within IoT is extremely important. As a result, studying and researchingauthentication issues within IoT is extremely important. This article presents a comparative study of recent researchin IoT security;it provides an analysis of recent authentication protocols from2019 to 2023 that cover several areaswithin IoT (such as smart cities, healthcare, and industry). This survey sought to provide an IoT security researchsummary, the biggest susceptibilities, and attacks, the appropriate technologies, and the most used simulators. Itillustrates that the resistance of protocols against attacks, and their computational and communication cost arelinked directly to the cryptography technique used to build it. Furthermore, it discusses the gaps in recent schemesand provides some future research directions.展开更多
In the existing ghost-imaging-based cryptographic key distribution(GCKD)protocols,the cryptographic keys need to be encoded by using many modulated patterns,which undoubtedly incurs long measurement time and huge memo...In the existing ghost-imaging-based cryptographic key distribution(GCKD)protocols,the cryptographic keys need to be encoded by using many modulated patterns,which undoubtedly incurs long measurement time and huge memory consumption.Given this,based on snapshot compressive ghost imaging,a public network cryptographic key distribution protocol is proposed,where the cryptographic keys and joint authentication information are encrypted into several color block diagrams to guarantee security.It transforms the previous single-pixel sequential multiple measurements into multi-pixel single exposure measurements,significantly reducing sampling time and memory storage.Both simulation and experimental results demonstrate the feasibility of this protocol and its ability to detect illegal attacks.Therefore,it takes GCKD a big step closer to practical applications.展开更多
With the development of hardware devices and the upgrading of smartphones,a large number of users save privacy-related information in mobile devices,mainly smartphones,which puts forward higher demands on the protecti...With the development of hardware devices and the upgrading of smartphones,a large number of users save privacy-related information in mobile devices,mainly smartphones,which puts forward higher demands on the protection of mobile users’privacy information.At present,mobile user authenticationmethods based on humancomputer interaction have been extensively studied due to their advantages of high precision and non-perception,but there are still shortcomings such as low data collection efficiency,untrustworthy participating nodes,and lack of practicability.To this end,this paper proposes a privacy-enhanced mobile user authentication method with motion sensors,which mainly includes:(1)Construct a smart contract-based private chain and federated learning to improve the data collection efficiency of mobile user authentication,reduce the probability of the model being bypassed by attackers,and reduce the overhead of data centralized processing and the risk of privacy leakage;(2)Use certificateless encryption to realize the authentication of the device to ensure the credibility of the client nodes participating in the calculation;(3)Combine Variational Mode Decomposition(VMD)and Long Short-TermMemory(LSTM)to analyze and model the motion sensor data of mobile devices to improve the accuracy of model certification.The experimental results on the real environment dataset of 1513 people show that themethod proposed in this paper can effectively resist poisoning attacks while ensuring the accuracy and efficiency of mobile user authentication.展开更多
Due to the rapid advancements in network technology,blockchain is being employed for distributed data storage.In the Internet of Things(IoT)scenario,different participants manage multiple blockchains located in differ...Due to the rapid advancements in network technology,blockchain is being employed for distributed data storage.In the Internet of Things(IoT)scenario,different participants manage multiple blockchains located in different trust domains,which has resulted in the extensive development of cross-domain authentication techniques.However,the emergence of many attackers equipped with quantum computers has the potential to launch quantum computing attacks against cross-domain authentication schemes based on traditional cryptography,posing a significant security threat.In response to the aforementioned challenges,our paper demonstrates a post-quantum cross-domain identity authentication scheme to negotiate the session key used in the cross-chain asset exchange process.Firstly,our paper designs the hiding and recovery process of user identity index based on lattice cryptography and introduces the identity-based signature from lattice to construct a post-quantum cross-domain authentication scheme.Secondly,our paper utilizes the hashed time-locked contract to achieves the cross-chain asset exchange of blockchain nodes in different trust domains.Furthermore,the security analysis reduces the security of the identity index and signature to Learning With Errors(LWE)and Short Integer Solution(SIS)assumption,respectively,indicating that our scheme has post-quantum security.Last but not least,through comparison analysis,we display that our scheme is efficient compared with the cross-domain authentication scheme based on traditional cryptography.展开更多
Machine-to-machine (M2M) communication plays a fundamental role in autonomous IoT (Internet of Things)-based infrastructure, a vital part of the fourth industrial revolution. Machine-type communication devices(MTCDs) ...Machine-to-machine (M2M) communication plays a fundamental role in autonomous IoT (Internet of Things)-based infrastructure, a vital part of the fourth industrial revolution. Machine-type communication devices(MTCDs) regularly share extensive data without human intervention while making all types of decisions. Thesedecisions may involve controlling sensitive ventilation systems maintaining uniform temperature, live heartbeatmonitoring, and several different alert systems. Many of these devices simultaneously share data to form anautomated system. The data shared between machine-type communication devices (MTCDs) is prone to risk dueto limited computational power, internal memory, and energy capacity. Therefore, securing the data and devicesbecomes challenging due to factors such as dynamic operational environments, remoteness, harsh conditions,and areas where human physical access is difficult. One of the crucial parts of securing MTCDs and data isauthentication, where each devicemust be verified before data transmission. SeveralM2Mauthentication schemeshave been proposed in the literature, however, the literature lacks a comprehensive overview of current M2Mauthentication techniques and the challenges associated with them. To utilize a suitable authentication schemefor specific scenarios, it is important to understand the challenges associated with it. Therefore, this article fillsthis gap by reviewing the state-of-the-art research on authentication schemes in MTCDs specifically concerningapplication categories, security provisions, and performance efficiency.展开更多
With the rapid advancement in exploring perceptual interactions and digital twins,metaverse technology has emerged to transcend the constraints of space-time and reality,facilitating remote AI-based collaboration.In t...With the rapid advancement in exploring perceptual interactions and digital twins,metaverse technology has emerged to transcend the constraints of space-time and reality,facilitating remote AI-based collaboration.In this dynamic metasystem environment,frequent information exchanges necessitate robust security measures,with Authentication and Key Agreement(AKA)serving as the primary line of defense to ensure communication security.However,traditional AKA protocols fall short in meeting the low-latency requirements essential for synchronous interactions within the metaverse.To address this challenge and enable nearly latency-free interactions,a novel low-latency AKA protocol based on chaotic maps is proposed.This protocol not only ensures mutual authentication of entities within the metasystem but also generates secure session keys.The security of these session keys is rigorously validated through formal proofs,formal verification,and informal proofs.When confronted with the Dolev-Yao(DY)threat model,the session keys are formally demonstrated to be secure under the Real-or-Random(ROR)model.The proposed protocol is further validated through simulations conducted using VMware workstation compiled in HLPSL language and C language.The simulation results affirm the protocol’s effectiveness in resisting well-known attacks while achieving the desired low latency for optimal metaverse interactions.展开更多
The dynamic landscape of the Internet of Things(IoT)is set to revolutionize the pace of interaction among entities,ushering in a proliferation of applications characterized by heightened quality and diversity.Among th...The dynamic landscape of the Internet of Things(IoT)is set to revolutionize the pace of interaction among entities,ushering in a proliferation of applications characterized by heightened quality and diversity.Among the pivotal applications within the realm of IoT,as a significant example,the Smart Grid(SG)evolves into intricate networks of energy deployment marked by data integration.This evolution concurrently entails data interchange with other IoT entities.However,there are also several challenges including data-sharing overheads and the intricate establishment of trusted centers in the IoT ecosystem.In this paper,we introduce a hierarchical secure data-sharing platform empowered by cloud-fog integration.Furthermore,we propose a novel non-interactive zero-knowledge proof-based group authentication and key agreement protocol that supports one-to-many sharing sets of IoT data,especially SG data.The security formal verification tool shows that the proposed scheme can achieve mutual authentication and secure data sharing while protecting the privacy of data providers.Compared with previous IoT data sharing schemes,the proposed scheme has advantages in both computational and transmission efficiency,and has more superiority with the increasing volume of shared data or increasing number of participants.展开更多
Wireless Sensor Network(WSN)is a distributed sensor network composed a large number of nodes with low cost,low performance and self-management.The special structure of WSN brings both convenience and vulnerability.For...Wireless Sensor Network(WSN)is a distributed sensor network composed a large number of nodes with low cost,low performance and self-management.The special structure of WSN brings both convenience and vulnerability.For example,a malicious participant can launch attacks by capturing a physical device.Therefore,node authentication that can resist malicious attacks is very important to network security.Recently,blockchain technology has shown the potential to enhance the security of the Internet of Things(IoT).In this paper,we propose a Blockchain-empowered Authentication Scheme(BAS)for WSN.In our scheme,all nodes are managed by utilizing the identity information stored on the blockchain.Besides,the simulation experiment about worm detection is executed on BAS,and the security is evaluated from detection and infection rate.The experiment results indicate that the proposed scheme can effectively inhibit the spread and infection of worms in the network.展开更多
BACKGROUND Phospholipase A2(PLA2)enzymes are pivotal in various biological processes,such as lipid mediator production,membrane remodeling,bioenergetics,and maintaining the body surface barrier.Notably,these enzymes p...BACKGROUND Phospholipase A2(PLA2)enzymes are pivotal in various biological processes,such as lipid mediator production,membrane remodeling,bioenergetics,and maintaining the body surface barrier.Notably,these enzymes play a significant role in the development of diverse tumors.AIM To systematically and comprehensively explore the expression of the PLA2 family genes and their potential implications in cholangiocarcinoma(CCA).METHODS We conducted an analysis of five CCA datasets from The Cancer Genome Atlas and the Gene Expression Omnibus.The study identified differentially expressed genes between tumor tissues and adjacent normal tissues,with a focus on PLA2G2A and PLA2G12B.Gene Set Enrichment Analysis was utilized to pinpoint associated pathways.Moreover,relevant hub genes and microRNAs for PLA2G2A and PLA2G12B were predicted,and their correlation with the prognosis of CCA was evaluated.RESULTS PLA2G2A and PLA2G12B were discerned as differentially expressed in CCA,manifesting significant variations in expression levels in urine and serum between CCA patients and healthy individuals.Elevated expression of PLA2G2A was correlated with poorer overall survival in CCA patients.Additionally,the study delineated pathways and miRNAs associated with these genes.CONCLUSION Our findings suggest that PLA2G2A and PLA2G12B may serve as novel potential diagnostic and prognostic markers for CCA.The increased levels of these genes in biological fluids could be employed as non-invasive markers for CCA,and their expression levels are indicative of prognosis,underscoring their potential utility in clinical settings.展开更多
Internet of Health Things(IoHT)is a subset of Internet of Things(IoT)technology that includes interconnected medical devices and sensors used in medical and healthcare information systems.However,IoHT is susceptible t...Internet of Health Things(IoHT)is a subset of Internet of Things(IoT)technology that includes interconnected medical devices and sensors used in medical and healthcare information systems.However,IoHT is susceptible to cybersecurity threats due to its reliance on low-power biomedical devices and the use of open wireless channels for communication.In this article,we intend to address this shortcoming,and as a result,we propose a new scheme called,the certificateless anonymous authentication(CAA)scheme.The proposed scheme is based on hyperelliptic curve cryptography(HECC),an enhanced variant of elliptic curve cryptography(ECC)that employs a smaller key size of 80 bits as compared to 160 bits.The proposed scheme is secure against various attacks in both formal and informal security analyses.The formal study makes use of the Real-or-Random(ROR)model.A thorough comparative study of the proposed scheme is conducted for the security and efficiency of the proposed scheme with the relevant existing schemes.The results demonstrate that the proposed scheme not only ensures high security for health-related data but also increases efficiency.The proposed scheme’s computation cost is 2.88 ms,and the communication cost is 1440 bits,which shows its better efficiency compared to its counterpart schemes.展开更多
基金supported by the National Natural Science Foundation of China (52373091,52173084,51973192,51603122)Shanxi-Zheda Institute of Advanced Materials and Chemical Engineering (2021SZ-FR002)。
文摘The Internet of Things(IoT)is a smart networking infrastructure of physical devices,i.e.,things,that are embedded with sensors,actuators,software,and other technologies,to connect and share data with the respective server module.Although IoTs are cornerstones in different application domains,the device’s authenticity,i.e.,of server(s)and ordinary devices,is the most crucial issue and must be resolved on a priority basis.Therefore,various field-proven methodologies were presented to streamline the verification process of the communicating devices;however,location-aware authentication has not been reported as per our knowledge,which is a crucial metric,especially in scenarios where devices are mobile.This paper presents a lightweight and location-aware device-to-server authentication technique where the device’s membership with the nearest server is subjected to its location information along with other measures.Initially,Media Access Control(MAC)address and Advance Encryption Scheme(AES)along with a secret shared key,i.e.,λ_(i) of 128 bits,have been utilized by Trusted Authority(TA)to generate MaskIDs,which are used instead of the original ID,for every device,i.e.,server and member,and are shared in the offline phase.Secondly,TA shares a list of authentic devices,i.e.,server S_(j) and members C_(i),with every device in the IoT for the onward verification process,which is required to be executed before the initialization of the actual communication process.Additionally,every device should be located such that it lies within the coverage area of a server,and this location information is used in the authentication process.A thorough analytical analysis was carried out to check the susceptibility of the proposed and existing authentication approaches against well-known intruder attacks,i.e.,man-in-the-middle,masquerading,device,and server impersonations,etc.,especially in the IoT domain.Moreover,proposed authentication and existing state-of-the-art approaches have been simulated in the real environment of IoT to verify their performance,particularly in terms of various evaluation metrics,i.e.,processing,communication,and storage overheads.These results have verified the superiority of the proposed scheme against existing state-of-the-art approaches,preferably in terms of communication,storage,and processing costs.
文摘Nowadays, devices are connected across all areas, from intelligent buildings and smart cities to Industry 4.0 andsmart healthcare. With the exponential growth of Internet of Things usage in our world, IoT security is still thebiggest challenge for its deployment. The main goal of IoT security is to ensure the accessibility of services providedby an IoT environment, protect privacy, and confidentiality, and guarantee the safety of IoT users, infrastructures,data, and devices. Authentication, as the first line of defense against security threats, becomes the priority ofeveryone. It can either grant or deny users access to resources according to their legitimacy. As a result, studyingand researching authentication issues within IoT is extremely important. As a result, studying and researchingauthentication issues within IoT is extremely important. This article presents a comparative study of recent researchin IoT security;it provides an analysis of recent authentication protocols from2019 to 2023 that cover several areaswithin IoT (such as smart cities, healthcare, and industry). This survey sought to provide an IoT security researchsummary, the biggest susceptibilities, and attacks, the appropriate technologies, and the most used simulators. Itillustrates that the resistance of protocols against attacks, and their computational and communication cost arelinked directly to the cryptography technique used to build it. Furthermore, it discusses the gaps in recent schemesand provides some future research directions.
基金supported by the Beijing Natural Science Foundation(Grant No.4222016).
文摘In the existing ghost-imaging-based cryptographic key distribution(GCKD)protocols,the cryptographic keys need to be encoded by using many modulated patterns,which undoubtedly incurs long measurement time and huge memory consumption.Given this,based on snapshot compressive ghost imaging,a public network cryptographic key distribution protocol is proposed,where the cryptographic keys and joint authentication information are encrypted into several color block diagrams to guarantee security.It transforms the previous single-pixel sequential multiple measurements into multi-pixel single exposure measurements,significantly reducing sampling time and memory storage.Both simulation and experimental results demonstrate the feasibility of this protocol and its ability to detect illegal attacks.Therefore,it takes GCKD a big step closer to practical applications.
基金Wenzhou Key Scientific and Technological Projects(No.ZG2020031)Wenzhou Polytechnic Research Projects(No.WZY2021002)+3 种基金Key R&D Projects in Zhejiang Province(No.2021C01117)Major Program of Natural Science Foundation of Zhejiang Province(LD22F020002)the Cloud Security Key Technology Research Laboratorythe Researchers Supporting Project Number(RSP2023R509),King Saud University,Riyadh,Saudi Arabia.
文摘With the development of hardware devices and the upgrading of smartphones,a large number of users save privacy-related information in mobile devices,mainly smartphones,which puts forward higher demands on the protection of mobile users’privacy information.At present,mobile user authenticationmethods based on humancomputer interaction have been extensively studied due to their advantages of high precision and non-perception,but there are still shortcomings such as low data collection efficiency,untrustworthy participating nodes,and lack of practicability.To this end,this paper proposes a privacy-enhanced mobile user authentication method with motion sensors,which mainly includes:(1)Construct a smart contract-based private chain and federated learning to improve the data collection efficiency of mobile user authentication,reduce the probability of the model being bypassed by attackers,and reduce the overhead of data centralized processing and the risk of privacy leakage;(2)Use certificateless encryption to realize the authentication of the device to ensure the credibility of the client nodes participating in the calculation;(3)Combine Variational Mode Decomposition(VMD)and Long Short-TermMemory(LSTM)to analyze and model the motion sensor data of mobile devices to improve the accuracy of model certification.The experimental results on the real environment dataset of 1513 people show that themethod proposed in this paper can effectively resist poisoning attacks while ensuring the accuracy and efficiency of mobile user authentication.
基金This work was supported by the Defense Industrial Technology Development Program(Grant No.JCKY2021208B036).
文摘Due to the rapid advancements in network technology,blockchain is being employed for distributed data storage.In the Internet of Things(IoT)scenario,different participants manage multiple blockchains located in different trust domains,which has resulted in the extensive development of cross-domain authentication techniques.However,the emergence of many attackers equipped with quantum computers has the potential to launch quantum computing attacks against cross-domain authentication schemes based on traditional cryptography,posing a significant security threat.In response to the aforementioned challenges,our paper demonstrates a post-quantum cross-domain identity authentication scheme to negotiate the session key used in the cross-chain asset exchange process.Firstly,our paper designs the hiding and recovery process of user identity index based on lattice cryptography and introduces the identity-based signature from lattice to construct a post-quantum cross-domain authentication scheme.Secondly,our paper utilizes the hashed time-locked contract to achieves the cross-chain asset exchange of blockchain nodes in different trust domains.Furthermore,the security analysis reduces the security of the identity index and signature to Learning With Errors(LWE)and Short Integer Solution(SIS)assumption,respectively,indicating that our scheme has post-quantum security.Last but not least,through comparison analysis,we display that our scheme is efficient compared with the cross-domain authentication scheme based on traditional cryptography.
基金the Deanship of Scientific Research,Vice Presidency for Graduate Studies and Scientific Research,King Faisal University,Saudi Arabia(Grant No.GRANT5,208).
文摘Machine-to-machine (M2M) communication plays a fundamental role in autonomous IoT (Internet of Things)-based infrastructure, a vital part of the fourth industrial revolution. Machine-type communication devices(MTCDs) regularly share extensive data without human intervention while making all types of decisions. Thesedecisions may involve controlling sensitive ventilation systems maintaining uniform temperature, live heartbeatmonitoring, and several different alert systems. Many of these devices simultaneously share data to form anautomated system. The data shared between machine-type communication devices (MTCDs) is prone to risk dueto limited computational power, internal memory, and energy capacity. Therefore, securing the data and devicesbecomes challenging due to factors such as dynamic operational environments, remoteness, harsh conditions,and areas where human physical access is difficult. One of the crucial parts of securing MTCDs and data isauthentication, where each devicemust be verified before data transmission. SeveralM2Mauthentication schemeshave been proposed in the literature, however, the literature lacks a comprehensive overview of current M2Mauthentication techniques and the challenges associated with them. To utilize a suitable authentication schemefor specific scenarios, it is important to understand the challenges associated with it. Therefore, this article fillsthis gap by reviewing the state-of-the-art research on authentication schemes in MTCDs specifically concerningapplication categories, security provisions, and performance efficiency.
基金This work has received funding from National Natural Science Foundation of China(No.42275157).
文摘With the rapid advancement in exploring perceptual interactions and digital twins,metaverse technology has emerged to transcend the constraints of space-time and reality,facilitating remote AI-based collaboration.In this dynamic metasystem environment,frequent information exchanges necessitate robust security measures,with Authentication and Key Agreement(AKA)serving as the primary line of defense to ensure communication security.However,traditional AKA protocols fall short in meeting the low-latency requirements essential for synchronous interactions within the metaverse.To address this challenge and enable nearly latency-free interactions,a novel low-latency AKA protocol based on chaotic maps is proposed.This protocol not only ensures mutual authentication of entities within the metasystem but also generates secure session keys.The security of these session keys is rigorously validated through formal proofs,formal verification,and informal proofs.When confronted with the Dolev-Yao(DY)threat model,the session keys are formally demonstrated to be secure under the Real-or-Random(ROR)model.The proposed protocol is further validated through simulations conducted using VMware workstation compiled in HLPSL language and C language.The simulation results affirm the protocol’s effectiveness in resisting well-known attacks while achieving the desired low latency for optimal metaverse interactions.
基金supported by the National Key R&D Program of China(No.2022YFB3103400)the National Natural Science Foundation of China under Grants 61932015 and 62172317.
文摘The dynamic landscape of the Internet of Things(IoT)is set to revolutionize the pace of interaction among entities,ushering in a proliferation of applications characterized by heightened quality and diversity.Among the pivotal applications within the realm of IoT,as a significant example,the Smart Grid(SG)evolves into intricate networks of energy deployment marked by data integration.This evolution concurrently entails data interchange with other IoT entities.However,there are also several challenges including data-sharing overheads and the intricate establishment of trusted centers in the IoT ecosystem.In this paper,we introduce a hierarchical secure data-sharing platform empowered by cloud-fog integration.Furthermore,we propose a novel non-interactive zero-knowledge proof-based group authentication and key agreement protocol that supports one-to-many sharing sets of IoT data,especially SG data.The security formal verification tool shows that the proposed scheme can achieve mutual authentication and secure data sharing while protecting the privacy of data providers.Compared with previous IoT data sharing schemes,the proposed scheme has advantages in both computational and transmission efficiency,and has more superiority with the increasing volume of shared data or increasing number of participants.
基金supported by the Natural Science Foundation under Grant No.61962009Major Scientific and Technological Special Project of Guizhou Province under Grant No.20183001Foundation of Guizhou Provincial Key Laboratory of Public Big Data under Grant No.2018BDKFJJ003,2018BDKFJJ005 and 2019BDKFJJ009.
文摘Wireless Sensor Network(WSN)is a distributed sensor network composed a large number of nodes with low cost,low performance and self-management.The special structure of WSN brings both convenience and vulnerability.For example,a malicious participant can launch attacks by capturing a physical device.Therefore,node authentication that can resist malicious attacks is very important to network security.Recently,blockchain technology has shown the potential to enhance the security of the Internet of Things(IoT).In this paper,we propose a Blockchain-empowered Authentication Scheme(BAS)for WSN.In our scheme,all nodes are managed by utilizing the identity information stored on the blockchain.Besides,the simulation experiment about worm detection is executed on BAS,and the security is evaluated from detection and infection rate.The experiment results indicate that the proposed scheme can effectively inhibit the spread and infection of worms in the network.
基金Supported by the Key Specialty Construction Project of Shanghai Pudong New Area Health Commission,No.PWZzk2022-17Shanghai East Hospital Clinical Research Project,No.DFLC2022019and the Featured Clinical Discipline Project of Shanghai Pudong District,No.PWYts2021-06.
文摘BACKGROUND Phospholipase A2(PLA2)enzymes are pivotal in various biological processes,such as lipid mediator production,membrane remodeling,bioenergetics,and maintaining the body surface barrier.Notably,these enzymes play a significant role in the development of diverse tumors.AIM To systematically and comprehensively explore the expression of the PLA2 family genes and their potential implications in cholangiocarcinoma(CCA).METHODS We conducted an analysis of five CCA datasets from The Cancer Genome Atlas and the Gene Expression Omnibus.The study identified differentially expressed genes between tumor tissues and adjacent normal tissues,with a focus on PLA2G2A and PLA2G12B.Gene Set Enrichment Analysis was utilized to pinpoint associated pathways.Moreover,relevant hub genes and microRNAs for PLA2G2A and PLA2G12B were predicted,and their correlation with the prognosis of CCA was evaluated.RESULTS PLA2G2A and PLA2G12B were discerned as differentially expressed in CCA,manifesting significant variations in expression levels in urine and serum between CCA patients and healthy individuals.Elevated expression of PLA2G2A was correlated with poorer overall survival in CCA patients.Additionally,the study delineated pathways and miRNAs associated with these genes.CONCLUSION Our findings suggest that PLA2G2A and PLA2G12B may serve as novel potential diagnostic and prognostic markers for CCA.The increased levels of these genes in biological fluids could be employed as non-invasive markers for CCA,and their expression levels are indicative of prognosis,underscoring their potential utility in clinical settings.
文摘Internet of Health Things(IoHT)is a subset of Internet of Things(IoT)technology that includes interconnected medical devices and sensors used in medical and healthcare information systems.However,IoHT is susceptible to cybersecurity threats due to its reliance on low-power biomedical devices and the use of open wireless channels for communication.In this article,we intend to address this shortcoming,and as a result,we propose a new scheme called,the certificateless anonymous authentication(CAA)scheme.The proposed scheme is based on hyperelliptic curve cryptography(HECC),an enhanced variant of elliptic curve cryptography(ECC)that employs a smaller key size of 80 bits as compared to 160 bits.The proposed scheme is secure against various attacks in both formal and informal security analyses.The formal study makes use of the Real-or-Random(ROR)model.A thorough comparative study of the proposed scheme is conducted for the security and efficiency of the proposed scheme with the relevant existing schemes.The results demonstrate that the proposed scheme not only ensures high security for health-related data but also increases efficiency.The proposed scheme’s computation cost is 2.88 ms,and the communication cost is 1440 bits,which shows its better efficiency compared to its counterpart schemes.
