Due to the mobility of users in an organization,inclusion of dynamic attributes such as time and location becomes the major challenge in Ciphertext-Policy Attribute-Based Encryption(CP-ABE).By considering this challen...Due to the mobility of users in an organization,inclusion of dynamic attributes such as time and location becomes the major challenge in Ciphertext-Policy Attribute-Based Encryption(CP-ABE).By considering this challenge;we focus to present dynamic time and location information in CP-ABE with mul-ti-authorization.Atfirst,along with the set of attributes of the users,their corre-sponding location is also embedded.Geohash is used to encode the latitude and longitude of the user’s position.Then,decrypt time period and access time period of users are defined using the new time tree(NTT)structure.The NTT sets the encrypted duration of the encrypted data and the valid access time of the private key on the data user’s private key.Besides,single authorization of attribute authority(AA)is extended as multi authorization for enhancing the effectiveness of key generation.Simulation results depict that the proposed CP-ABE achieves better encryption time,decryption time,security level and memory usage.Namely,encryption time and decryption time of the proposed CP-ABE are reduced to 19%and 16%than that of existing CP-ABE scheme.展开更多
Over the years immunotherapy has demonstrably improved the field of cancer treatment.However,achieving long-term survival for colorectal cancer(CRC)patients remains a significant unmet need.Combination immunotherapies...Over the years immunotherapy has demonstrably improved the field of cancer treatment.However,achieving long-term survival for colorectal cancer(CRC)patients remains a significant unmet need.Combination immunotherapies incor-porating targeted drugs like MEK or multi-kinase inhibitors have offered some palliative benefit.Nevertheless,substantial gaps remain in the current therapeutic armamentarium for CRC.In recent years,there has been a surge of interest in exploring novel treatment strategies,including the application of light-activated drugs in conjunction with optical devices.This approach holds promise for achie-ving localized and targeted delivery of cytotoxic agents,such as microtubule-targeting drugs,directly to cancerous cells within the colon.展开更多
BACKGROUND Heart failure(HF),a common cardiovascular condition,is characterized by significant morbidity and mortality.While traditional Chinese medicine(TCM)is often used as a complementary approach in HF management,...BACKGROUND Heart failure(HF),a common cardiovascular condition,is characterized by significant morbidity and mortality.While traditional Chinese medicine(TCM)is often used as a complementary approach in HF management,systematic evalua-tions of its impact on clinical outcomes,TCM syndrome scores,and B-type natriuretic peptide(BNP)levels are lacking.This study fills this gap through a comprehensive analysis of randomized controlled trials(RCTs)focusing on TCM for HF treatment.It encompasses an assessment of methodological quality,a meta-analysis,and an evaluation of evidence quality based on established standards.The results offer crucial insights into the potential advantages and constraints of TCM in HF management.RCTs on TCM for HF treatment published since the establishment of the database were searched in four Chinese and English databases,including China National Knowledge Infrastructure,Wanfang,VIP Information Chinese Science and Technology Journal,and PubMed.Methodological quality was assessed for the included studies with the Cochrane risk-of-bias assessment tool,and the meta-analysis and publication bias assessment was performed with the RevMan5.3 software.Finally,the quality of evidence was rated according to the GRADE criteria.RESULTS A total of 1098 RCTs were initially retrieved.After screening,16 RCTs were finally included in our study,which were published between 2020 and 2023.These RCTs involved 1660 HF patients,including 832 in the TCM group[TCM combined with conventional Western medicine(CMW)treatment]and 828 in the CWM group(CWM treatment).The course of treatments varied from 1 wk to 3 months.TCM syndrome differentiation was analyzed in 11 of the included RCTs.In all included RCTs,outcome indicators included comprehensive clinical outcomes,TCM syndrome scores,and BNP levels.The meta-analysis results showed significant differences between the TCM and CWM groups in terms of comprehensive clinical outcomes[risk ratio=-0.54;95%confidence interval(CI)=-0.61,-0.47;P<0.00001],TCM syndrome scores[weighted mean difference(WMD)=-142.07;95%CI=-147.56,-136.57;P<0.00001],and BNP levels(WMD=-142.07;95%CI=-147.56,-136.57;P<0.00001).According to the GRADE criteria,RCTs where"TCM improves clinical comprehensive outcomes"were rated as low-quality evidence,and RCTs where"TCM reduces TCM syndrome scores"or"TCM decreases BNP levels"were rated as medium-quality evidence.CONCLUSION TCM combined with CWM treatment effectively improves comprehensive clinical outcomes and diminishes TCM syndrome scores and BNP levels in HF patients.Given the low and medium quality of the included RCTs,the application of these results should be cautious.展开更多
Recently,the Darna distribution has been introduced as a new lifetime distribution.The two-parameter Darna distribution represents is a mixture of two well-known gamma and exponential distributions.A manufacturer or a...Recently,the Darna distribution has been introduced as a new lifetime distribution.The two-parameter Darna distribution represents is a mixture of two well-known gamma and exponential distributions.A manufacturer or an engineer of products conducts life testing to examine whether the quality level of products meets the customer’s requirements,such as reliability or the minimum lifetime.In this article,an attribute modified chain sampling inspection plan based on the time truncated life test is proposed for items whose lifetime follows the Darna distribution.The plan parameters,including the sample size,the acceptance number,and the past lot result of the proposed sampling plan,are determined with the help of the two-point approach considering the acceptable quality level(AQL)and the limiting quality level(LQL).The plan parameters and the corresponding operating characteristic functions of a new plan are provided in tabular form for various Darna distribution parameters.Also,a few illustrated examples are presented for various distribution parameters.The usefulness of the proposed attribute modified chain sampling plan is investigated using two real failure time datasets.The results indicate that the proposed sampling plan can reduce the sample size when the termination ratio increases for fixed values of the producer’s risk and acceptance number.Hence,the proposed attribute modified chain sampling inspection plan is recommended to practitioners in the field.展开更多
The dissociation between data management and data ownership makes it difficult to protect data security and privacy in cloud storage systems.Traditional encryption technologies are not suitable for data protection in ...The dissociation between data management and data ownership makes it difficult to protect data security and privacy in cloud storage systems.Traditional encryption technologies are not suitable for data protection in cloud storage systems.A novel multi-authority proxy re-encryption mechanism based on ciphertext-policy attribute-based encryption（MPRE-CPABE） is proposed for cloud storage systems.MPRE-CPABE requires data owner to split each file into two blocks,one big block and one small block.The small block is used to encrypt the big one as the private key,and then the encrypted big block will be uploaded to the cloud storage system.Even if the uploaded big block of file is stolen,illegal users cannot get the complete information of the file easily.Ciphertext-policy attribute-based encryption（CPABE）is always criticized for its heavy overload and insecure issues when distributing keys or revoking user＇s access right.MPRE-CPABE applies CPABE to the multi-authority cloud storage system,and solves the above issues.The weighted access structure（WAS） is proposed to support a variety of fine-grained threshold access control policy in multi-authority environments,and reduce the computational cost of key distribution.Meanwhile,MPRE-CPABE uses proxy re-encryption to reduce the computational cost of access revocation.Experiments are implemented on platforms of Ubuntu and CloudSim.Experimental results show that MPRE-CPABE can greatly reduce the computational cost of the generation of key components and the revocation of user＇s access right.MPRE-CPABE is also proved secure under the security model of decisional bilinear Diffie-Hellman（DBDH）.展开更多
TrustedRBAC is a scalable, decentralized trust-management and access control mechanism for systems that span multiple autonomous domains. We utilize X.509 attri- bute certificates to define trust domains, roles to def...TrustedRBAC is a scalable, decentralized trust-management and access control mechanism for systems that span multiple autonomous domains. We utilize X.509 attri- bute certificates to define trust domains, roles to define controlled activities, and role delegation across domains to represent permissions to these activities. This paper describes the TrustedRBAC model and its scalable design and implementation.展开更多
We have made a clerical error in Table 1 on the page of 239, Volume 23, No.4 of Journal of Medical Colleges of PLA (the article is entitled as Expression and role of AQP1 in cervical squamous carcinoma
To editorial board of Acta Mathematica Scientia(Acta MS) I was shocked when I was informed that the paper entitled"Eigenvalue Problem for the Laplacian Equations"by Shao Zhiqiang and Hong Jiaxing appeared in...To editorial board of Acta Mathematica Scientia(Acta MS) I was shocked when I was informed that the paper entitled"Eigenvalue Problem for the Laplacian Equations"by Shao Zhiqiang and Hong Jiaxing appeared in Acta MS(2007)Series B,no 2.For the past 15 years,I have not had any contact with Mr.Shao Zhiqiang and I have展开更多
Aims andscope of the Journal.Medical Journal of Chinese People's Liberation Army(Med J Chin PLA)is a multiple-subjects medical periodical published by the People's Military Medical Press,under the auspice of D...Aims andscope of the Journal.Medical Journal of Chinese People's Liberation Army(Med J Chin PLA)is a multiple-subjects medical periodical published by the People's Military Medical Press,under the auspice of Department of Health,General Logistics Department of PLA,and it展开更多
Aims and scope of the Journal. Medical Journal of Chinese People’s Liberation Army (Med J Chin PLA) is a multiple-subjects medical periodical published by the People’s Military Medical Press, under the auspice of De...Aims and scope of the Journal. Medical Journal of Chinese People’s Liberation Army (Med J Chin PLA) is a multiple-subjects medical periodical published by the People’s Military Medical Press, under the auspice of Department of Health, General Logistics Department of PLA, and it is issued domestically and abroad. Med J Chin PLA has become one of the source journals of statistics in Chinese Scientific Thesis and Chinese Scientific Quotation Database, the key periodical of multiple-subject medical journals, and is a prize journal of National Periodical Award and one of the Top Hundred Periodicals in China. Med J Chin PLA is issued monthly. Its permanent sections include Expert Forum, Research on Special Topics, Medical Treatises, Experimental Research, Clinical Research, Technology and Methodology, Discussion of Knotty Cases (Pathology), Reviews, Military Medical Sciences, News in Medicine etc. Manuscripts sent by both domestic and overseas writers are welcome. Contribution of reviews is usually invited by the Editors, but recommendations for topics and authors are welcomed.展开更多
Aims andscope of the Journal .Medical Journal of Chinese People’s Liberation Army (Med J Chin PLA) is a multiple-subjects medical periodical published by the People’s Military Medical Press,under the auspice of Depa...Aims andscope of the Journal .Medical Journal of Chinese People’s Liberation Army (Med J Chin PLA) is a multiple-subjects medical periodical published by the People’s Military Medical Press,under the auspice of Department ofHealth, General Logistics Department of PLA,andit is issued展开更多
文摘Due to the mobility of users in an organization,inclusion of dynamic attributes such as time and location becomes the major challenge in Ciphertext-Policy Attribute-Based Encryption(CP-ABE).By considering this challenge;we focus to present dynamic time and location information in CP-ABE with mul-ti-authorization.Atfirst,along with the set of attributes of the users,their corre-sponding location is also embedded.Geohash is used to encode the latitude and longitude of the user’s position.Then,decrypt time period and access time period of users are defined using the new time tree(NTT)structure.The NTT sets the encrypted duration of the encrypted data and the valid access time of the private key on the data user’s private key.Besides,single authorization of attribute authority(AA)is extended as multi authorization for enhancing the effectiveness of key generation.Simulation results depict that the proposed CP-ABE achieves better encryption time,decryption time,security level and memory usage.Namely,encryption time and decryption time of the proposed CP-ABE are reduced to 19%and 16%than that of existing CP-ABE scheme.
文摘Over the years immunotherapy has demonstrably improved the field of cancer treatment.However,achieving long-term survival for colorectal cancer(CRC)patients remains a significant unmet need.Combination immunotherapies incor-porating targeted drugs like MEK or multi-kinase inhibitors have offered some palliative benefit.Nevertheless,substantial gaps remain in the current therapeutic armamentarium for CRC.In recent years,there has been a surge of interest in exploring novel treatment strategies,including the application of light-activated drugs in conjunction with optical devices.This approach holds promise for achie-ving localized and targeted delivery of cytotoxic agents,such as microtubule-targeting drugs,directly to cancerous cells within the colon.
文摘BACKGROUND Heart failure(HF),a common cardiovascular condition,is characterized by significant morbidity and mortality.While traditional Chinese medicine(TCM)is often used as a complementary approach in HF management,systematic evalua-tions of its impact on clinical outcomes,TCM syndrome scores,and B-type natriuretic peptide(BNP)levels are lacking.This study fills this gap through a comprehensive analysis of randomized controlled trials(RCTs)focusing on TCM for HF treatment.It encompasses an assessment of methodological quality,a meta-analysis,and an evaluation of evidence quality based on established standards.The results offer crucial insights into the potential advantages and constraints of TCM in HF management.RCTs on TCM for HF treatment published since the establishment of the database were searched in four Chinese and English databases,including China National Knowledge Infrastructure,Wanfang,VIP Information Chinese Science and Technology Journal,and PubMed.Methodological quality was assessed for the included studies with the Cochrane risk-of-bias assessment tool,and the meta-analysis and publication bias assessment was performed with the RevMan5.3 software.Finally,the quality of evidence was rated according to the GRADE criteria.RESULTS A total of 1098 RCTs were initially retrieved.After screening,16 RCTs were finally included in our study,which were published between 2020 and 2023.These RCTs involved 1660 HF patients,including 832 in the TCM group[TCM combined with conventional Western medicine(CMW)treatment]and 828 in the CWM group(CWM treatment).The course of treatments varied from 1 wk to 3 months.TCM syndrome differentiation was analyzed in 11 of the included RCTs.In all included RCTs,outcome indicators included comprehensive clinical outcomes,TCM syndrome scores,and BNP levels.The meta-analysis results showed significant differences between the TCM and CWM groups in terms of comprehensive clinical outcomes[risk ratio=-0.54;95%confidence interval(CI)=-0.61,-0.47;P<0.00001],TCM syndrome scores[weighted mean difference(WMD)=-142.07;95%CI=-147.56,-136.57;P<0.00001],and BNP levels(WMD=-142.07;95%CI=-147.56,-136.57;P<0.00001).According to the GRADE criteria,RCTs where"TCM improves clinical comprehensive outcomes"were rated as low-quality evidence,and RCTs where"TCM reduces TCM syndrome scores"or"TCM decreases BNP levels"were rated as medium-quality evidence.CONCLUSION TCM combined with CWM treatment effectively improves comprehensive clinical outcomes and diminishes TCM syndrome scores and BNP levels in HF patients.Given the low and medium quality of the included RCTs,the application of these results should be cautious.
基金A.R.A.Alanzi would like to thank the Deanship of Scientific Research at Majmaah University for financial support and encouragement.
文摘Recently,the Darna distribution has been introduced as a new lifetime distribution.The two-parameter Darna distribution represents is a mixture of two well-known gamma and exponential distributions.A manufacturer or an engineer of products conducts life testing to examine whether the quality level of products meets the customer’s requirements,such as reliability or the minimum lifetime.In this article,an attribute modified chain sampling inspection plan based on the time truncated life test is proposed for items whose lifetime follows the Darna distribution.The plan parameters,including the sample size,the acceptance number,and the past lot result of the proposed sampling plan,are determined with the help of the two-point approach considering the acceptable quality level(AQL)and the limiting quality level(LQL).The plan parameters and the corresponding operating characteristic functions of a new plan are provided in tabular form for various Darna distribution parameters.Also,a few illustrated examples are presented for various distribution parameters.The usefulness of the proposed attribute modified chain sampling plan is investigated using two real failure time datasets.The results indicate that the proposed sampling plan can reduce the sample size when the termination ratio increases for fixed values of the producer’s risk and acceptance number.Hence,the proposed attribute modified chain sampling inspection plan is recommended to practitioners in the field.
基金supported by the National Natural Science Foundation of China(6120200461472192)+1 种基金the Special Fund for Fast Sharing of Science Paper in Net Era by CSTD(2013116)the Natural Science Fund of Higher Education of Jiangsu Province(14KJB520014)
文摘The dissociation between data management and data ownership makes it difficult to protect data security and privacy in cloud storage systems.Traditional encryption technologies are not suitable for data protection in cloud storage systems.A novel multi-authority proxy re-encryption mechanism based on ciphertext-policy attribute-based encryption（MPRE-CPABE） is proposed for cloud storage systems.MPRE-CPABE requires data owner to split each file into two blocks,one big block and one small block.The small block is used to encrypt the big one as the private key,and then the encrypted big block will be uploaded to the cloud storage system.Even if the uploaded big block of file is stolen,illegal users cannot get the complete information of the file easily.Ciphertext-policy attribute-based encryption（CPABE）is always criticized for its heavy overload and insecure issues when distributing keys or revoking user＇s access right.MPRE-CPABE applies CPABE to the multi-authority cloud storage system,and solves the above issues.The weighted access structure（WAS） is proposed to support a variety of fine-grained threshold access control policy in multi-authority environments,and reduce the computational cost of key distribution.Meanwhile,MPRE-CPABE uses proxy re-encryption to reduce the computational cost of access revocation.Experiments are implemented on platforms of Ubuntu and CloudSim.Experimental results show that MPRE-CPABE can greatly reduce the computational cost of the generation of key components and the revocation of user＇s access right.MPRE-CPABE is also proved secure under the security model of decisional bilinear Diffie-Hellman（DBDH）.
文摘TrustedRBAC is a scalable, decentralized trust-management and access control mechanism for systems that span multiple autonomous domains. We utilize X.509 attri- bute certificates to define trust domains, roles to define controlled activities, and role delegation across domains to represent permissions to these activities. This paper describes the TrustedRBAC model and its scalable design and implementation.
文摘We have made a clerical error in Table 1 on the page of 239, Volume 23, No.4 of Journal of Medical Colleges of PLA (the article is entitled as Expression and role of AQP1 in cervical squamous carcinoma
文摘To editorial board of Acta Mathematica Scientia(Acta MS) I was shocked when I was informed that the paper entitled"Eigenvalue Problem for the Laplacian Equations"by Shao Zhiqiang and Hong Jiaxing appeared in Acta MS(2007)Series B,no 2.For the past 15 years,I have not had any contact with Mr.Shao Zhiqiang and I have
文摘Aims andscope of the Journal.Medical Journal of Chinese People's Liberation Army(Med J Chin PLA)is a multiple-subjects medical periodical published by the People's Military Medical Press,under the auspice of Department of Health,General Logistics Department of PLA,and it
文摘Aims and scope of the Journal. Medical Journal of Chinese People’s Liberation Army (Med J Chin PLA) is a multiple-subjects medical periodical published by the People’s Military Medical Press, under the auspice of Department of Health, General Logistics Department of PLA, and it is issued domestically and abroad. Med J Chin PLA has become one of the source journals of statistics in Chinese Scientific Thesis and Chinese Scientific Quotation Database, the key periodical of multiple-subject medical journals, and is a prize journal of National Periodical Award and one of the Top Hundred Periodicals in China. Med J Chin PLA is issued monthly. Its permanent sections include Expert Forum, Research on Special Topics, Medical Treatises, Experimental Research, Clinical Research, Technology and Methodology, Discussion of Knotty Cases (Pathology), Reviews, Military Medical Sciences, News in Medicine etc. Manuscripts sent by both domestic and overseas writers are welcome. Contribution of reviews is usually invited by the Editors, but recommendations for topics and authors are welcomed.
文摘Aims andscope of the Journal .Medical Journal of Chinese People’s Liberation Army (Med J Chin PLA) is a multiple-subjects medical periodical published by the People’s Military Medical Press,under the auspice of Department ofHealth, General Logistics Department of PLA,andit is issued
