Over the years immunotherapy has demonstrably improved the field of cancer treatment.However,achieving long-term survival for colorectal cancer(CRC)patients remains a significant unmet need.Combination immunotherapies...Over the years immunotherapy has demonstrably improved the field of cancer treatment.However,achieving long-term survival for colorectal cancer(CRC)patients remains a significant unmet need.Combination immunotherapies incor-porating targeted drugs like MEK or multi-kinase inhibitors have offered some palliative benefit.Nevertheless,substantial gaps remain in the current therapeutic armamentarium for CRC.In recent years,there has been a surge of interest in exploring novel treatment strategies,including the application of light-activated drugs in conjunction with optical devices.This approach holds promise for achie-ving localized and targeted delivery of cytotoxic agents,such as microtubule-targeting drugs,directly to cancerous cells within the colon.展开更多
BACKGROUND Heart failure(HF),a common cardiovascular condition,is characterized by significant morbidity and mortality.While traditional Chinese medicine(TCM)is often used as a complementary approach in HF management,...BACKGROUND Heart failure(HF),a common cardiovascular condition,is characterized by significant morbidity and mortality.While traditional Chinese medicine(TCM)is often used as a complementary approach in HF management,systematic evalua-tions of its impact on clinical outcomes,TCM syndrome scores,and B-type natriuretic peptide(BNP)levels are lacking.This study fills this gap through a comprehensive analysis of randomized controlled trials(RCTs)focusing on TCM for HF treatment.It encompasses an assessment of methodological quality,a meta-analysis,and an evaluation of evidence quality based on established standards.The results offer crucial insights into the potential advantages and constraints of TCM in HF management.RCTs on TCM for HF treatment published since the establishment of the database were searched in four Chinese and English databases,including China National Knowledge Infrastructure,Wanfang,VIP Information Chinese Science and Technology Journal,and PubMed.Methodological quality was assessed for the included studies with the Cochrane risk-of-bias assessment tool,and the meta-analysis and publication bias assessment was performed with the RevMan5.3 software.Finally,the quality of evidence was rated according to the GRADE criteria.RESULTS A total of 1098 RCTs were initially retrieved.After screening,16 RCTs were finally included in our study,which were published between 2020 and 2023.These RCTs involved 1660 HF patients,including 832 in the TCM group[TCM combined with conventional Western medicine(CMW)treatment]and 828 in the CWM group(CWM treatment).The course of treatments varied from 1 wk to 3 months.TCM syndrome differentiation was analyzed in 11 of the included RCTs.In all included RCTs,outcome indicators included comprehensive clinical outcomes,TCM syndrome scores,and BNP levels.The meta-analysis results showed significant differences between the TCM and CWM groups in terms of comprehensive clinical outcomes[risk ratio=-0.54;95%confidence interval(CI)=-0.61,-0.47;P<0.00001],TCM syndrome scores[weighted mean difference(WMD)=-142.07;95%CI=-147.56,-136.57;P<0.00001],and BNP levels(WMD=-142.07;95%CI=-147.56,-136.57;P<0.00001).According to the GRADE criteria,RCTs where"TCM improves clinical comprehensive outcomes"were rated as low-quality evidence,and RCTs where"TCM reduces TCM syndrome scores"or"TCM decreases BNP levels"were rated as medium-quality evidence.CONCLUSION TCM combined with CWM treatment effectively improves comprehensive clinical outcomes and diminishes TCM syndrome scores and BNP levels in HF patients.Given the low and medium quality of the included RCTs,the application of these results should be cautious.展开更多
Writer identity in academic writing has long been ignored by developing L2 writers.Moreover,research has much focused on the reader in shaping writing,and treated the role of the writer as unproblematic.In this essay,...Writer identity in academic writing has long been ignored by developing L2 writers.Moreover,research has much focused on the reader in shaping writing,and treated the role of the writer as unproblematic.In this essay,the construction of writer identity in developing writers’academic writing practice will be explored through a review of some relevant literature research and gain insights for the development of writer apprentices and writing instruction.展开更多
It is commonly known that writing is an advanced skill which is essential in language learning but at the same time the most difficult task for learners. This paper is with the aim to explore helpful roles that teache...It is commonly known that writing is an advanced skill which is essential in language learning but at the same time the most difficult task for learners. This paper is with the aim to explore helpful roles that teacher can play to help non-English major students improve their English writing, so as to help improve their writing ability in the author's context.展开更多
Although the story continuation writing task(SCWT) has attracted much research attention, few studies have investigated the construct of the task, particularly with respect to which language competence it focuses on. ...Although the story continuation writing task(SCWT) has attracted much research attention, few studies have investigated the construct of the task, particularly with respect to which language competence it focuses on. In addition, although some studies have demonstrated that China’s Standards of English Language Ability(CSE) provides comprehensive insights into the development of Chinese learners’ English language proficiency, little research has investigated the relationship between CSE and SCWT. This study drew upon the CSE to develop an SCWT language use inventory to address the above research gaps. A total of 358 high school students were asked to complete the questionnaire, of which 277 valid responses were analyzed. Exploratory factor analysis(EFA) on the CSE-based questionnaire revealed the presence of six factors, namely language correctness, language variety, task planning, connecting-and-generating, selecting-andmining, and organizing. The strategy of connecting-and-generating was the only significant predictor of the learners’ SCWT scores. The paper also discusses the findings relating to the SCWT rating and other integrated writing tasks.展开更多
Based on the researches of language transfer,contrastive analysis and error analysis,this paper tries to investigate the negative transfer of Chinese on Chinese students'English writings from the perspective of sy...Based on the researches of language transfer,contrastive analysis and error analysis,this paper tries to investigate the negative transfer of Chinese on Chinese students'English writings from the perspective of syntax.During one and a half months'teaching practice in Shannxi Hanzhong No.1 Middle School,the author lived through the real teaching process and found that there were lots of problems in students'English writings.The author makes a contrastive study of the different characteristics existing in Chinese and English languag es at the level of syntax,and analyses the typical syntactic errors appearing in the 60 students'English compositions collected from one or dinary class.These syntactic errors are caused by the negative transfer of Chinese.The purpose of the investigation is to study in what pat tern students have been influenced by Chinese in their English writings.Based on the findings and analysis of the mother tongue transfer on English writings,some implications are also provided in order to help minimize or eliminate the interference of negative transfer of the Chinese in students'English writings and improve the teaching and learning of English.展开更多
We have made a clerical error in Table 1 on the page of 239, Volume 23, No.4 of Journal of Medical Colleges of PLA (the article is entitled as Expression and role of AQP1 in cervical squamous carcinoma
To editorial board of Acta Mathematica Scientia(Acta MS) I was shocked when I was informed that the paper entitled"Eigenvalue Problem for the Laplacian Equations"by Shao Zhiqiang and Hong Jiaxing appeared in...To editorial board of Acta Mathematica Scientia(Acta MS) I was shocked when I was informed that the paper entitled"Eigenvalue Problem for the Laplacian Equations"by Shao Zhiqiang and Hong Jiaxing appeared in Acta MS(2007)Series B,no 2.For the past 15 years,I have not had any contact with Mr.Shao Zhiqiang and I have展开更多
Western travel writings about China provided material driving and theoretical guidance for the Age of Discovery, and became the main spiritual motive of the Westerners voyage to the East. In the Age of Discovery, the ...Western travel writings about China provided material driving and theoretical guidance for the Age of Discovery, and became the main spiritual motive of the Westerners voyage to the East. In the Age of Discovery, the image of China in the eyes of Western envoys, merchants and missionaries begun to fade away from traditional mythological and psychedelic colors, and the image of cultural elements such as material, spirit and history become clear. These Western travelers tried to shape the image of China as a state of civilization and wisdom, a state of moral order, and a state of wealth and power. On the basis of the continued description of the kingship and wealth of the Middle Ages, they constructed an overall image of China as a powerful state of civilization and wealth, thus forming a new frame of reference for cognition of China.展开更多
Aims andscope of the Journal.Medical Journal of Chinese People's Liberation Army(Med J Chin PLA)is a multiple-subjects medical periodical published by the People's Military Medical Press,under the auspice of D...Aims andscope of the Journal.Medical Journal of Chinese People's Liberation Army(Med J Chin PLA)is a multiple-subjects medical periodical published by the People's Military Medical Press,under the auspice of Department of Health,General Logistics Department of PLA,and it展开更多
Aims and scope of the Journal. Medical Journal of Chinese People’s Liberation Army (Med J Chin PLA) is a multiple-subjects medical periodical published by the People’s Military Medical Press, under the auspice of De...Aims and scope of the Journal. Medical Journal of Chinese People’s Liberation Army (Med J Chin PLA) is a multiple-subjects medical periodical published by the People’s Military Medical Press, under the auspice of Department of Health, General Logistics Department of PLA, and it is issued domestically and abroad. Med J Chin PLA has become one of the source journals of statistics in Chinese Scientific Thesis and Chinese Scientific Quotation Database, the key periodical of multiple-subject medical journals, and is a prize journal of National Periodical Award and one of the Top Hundred Periodicals in China. Med J Chin PLA is issued monthly. Its permanent sections include Expert Forum, Research on Special Topics, Medical Treatises, Experimental Research, Clinical Research, Technology and Methodology, Discussion of Knotty Cases (Pathology), Reviews, Military Medical Sciences, News in Medicine etc. Manuscripts sent by both domestic and overseas writers are welcome. Contribution of reviews is usually invited by the Editors, but recommendations for topics and authors are welcomed.展开更多
Aims andscope of the Journal .Medical Journal of Chinese People’s Liberation Army (Med J Chin PLA) is a multiple-subjects medical periodical published by the People’s Military Medical Press,under the auspice of Depa...Aims andscope of the Journal .Medical Journal of Chinese People’s Liberation Army (Med J Chin PLA) is a multiple-subjects medical periodical published by the People’s Military Medical Press,under the auspice of Department ofHealth, General Logistics Department of PLA,andit is issued展开更多
Academic writings, whether they are BA dissertations or semester papers, are important carriers of one＇s ideas and findings of their own study and research spheres. In academic papers, the most important part is the ...Academic writings, whether they are BA dissertations or semester papers, are important carriers of one＇s ideas and findings of their own study and research spheres. In academic papers, the most important part is the choice of topics which determines the macro direction of the paper. Important as it is, it is difficult for the English majors to choose the most appropriate topics with idea-invested thesis statements instead of some factual statements. Therefore, in order to make clear of the status quo and underlying obstacles of topic choosing, this paper is to study on 98 samples from China University of Political Science and Law＇s junior English majors. By observing and analyzing their writings, the paper intends to fred out some possible and accessible methods to improve English majors＇ academic writing and offer some insights for teachers to make some adjustments in accordance with the status quo.展开更多
文摘Over the years immunotherapy has demonstrably improved the field of cancer treatment.However,achieving long-term survival for colorectal cancer(CRC)patients remains a significant unmet need.Combination immunotherapies incor-porating targeted drugs like MEK or multi-kinase inhibitors have offered some palliative benefit.Nevertheless,substantial gaps remain in the current therapeutic armamentarium for CRC.In recent years,there has been a surge of interest in exploring novel treatment strategies,including the application of light-activated drugs in conjunction with optical devices.This approach holds promise for achie-ving localized and targeted delivery of cytotoxic agents,such as microtubule-targeting drugs,directly to cancerous cells within the colon.
文摘BACKGROUND Heart failure(HF),a common cardiovascular condition,is characterized by significant morbidity and mortality.While traditional Chinese medicine(TCM)is often used as a complementary approach in HF management,systematic evalua-tions of its impact on clinical outcomes,TCM syndrome scores,and B-type natriuretic peptide(BNP)levels are lacking.This study fills this gap through a comprehensive analysis of randomized controlled trials(RCTs)focusing on TCM for HF treatment.It encompasses an assessment of methodological quality,a meta-analysis,and an evaluation of evidence quality based on established standards.The results offer crucial insights into the potential advantages and constraints of TCM in HF management.RCTs on TCM for HF treatment published since the establishment of the database were searched in four Chinese and English databases,including China National Knowledge Infrastructure,Wanfang,VIP Information Chinese Science and Technology Journal,and PubMed.Methodological quality was assessed for the included studies with the Cochrane risk-of-bias assessment tool,and the meta-analysis and publication bias assessment was performed with the RevMan5.3 software.Finally,the quality of evidence was rated according to the GRADE criteria.RESULTS A total of 1098 RCTs were initially retrieved.After screening,16 RCTs were finally included in our study,which were published between 2020 and 2023.These RCTs involved 1660 HF patients,including 832 in the TCM group[TCM combined with conventional Western medicine(CMW)treatment]and 828 in the CWM group(CWM treatment).The course of treatments varied from 1 wk to 3 months.TCM syndrome differentiation was analyzed in 11 of the included RCTs.In all included RCTs,outcome indicators included comprehensive clinical outcomes,TCM syndrome scores,and BNP levels.The meta-analysis results showed significant differences between the TCM and CWM groups in terms of comprehensive clinical outcomes[risk ratio=-0.54;95%confidence interval(CI)=-0.61,-0.47;P<0.00001],TCM syndrome scores[weighted mean difference(WMD)=-142.07;95%CI=-147.56,-136.57;P<0.00001],and BNP levels(WMD=-142.07;95%CI=-147.56,-136.57;P<0.00001).According to the GRADE criteria,RCTs where"TCM improves clinical comprehensive outcomes"were rated as low-quality evidence,and RCTs where"TCM reduces TCM syndrome scores"or"TCM decreases BNP levels"were rated as medium-quality evidence.CONCLUSION TCM combined with CWM treatment effectively improves comprehensive clinical outcomes and diminishes TCM syndrome scores and BNP levels in HF patients.Given the low and medium quality of the included RCTs,the application of these results should be cautious.
文摘Writer identity in academic writing has long been ignored by developing L2 writers.Moreover,research has much focused on the reader in shaping writing,and treated the role of the writer as unproblematic.In this essay,the construction of writer identity in developing writers’academic writing practice will be explored through a review of some relevant literature research and gain insights for the development of writer apprentices and writing instruction.
文摘It is commonly known that writing is an advanced skill which is essential in language learning but at the same time the most difficult task for learners. This paper is with the aim to explore helpful roles that teacher can play to help non-English major students improve their English writing, so as to help improve their writing ability in the author's context.
文摘Although the story continuation writing task(SCWT) has attracted much research attention, few studies have investigated the construct of the task, particularly with respect to which language competence it focuses on. In addition, although some studies have demonstrated that China’s Standards of English Language Ability(CSE) provides comprehensive insights into the development of Chinese learners’ English language proficiency, little research has investigated the relationship between CSE and SCWT. This study drew upon the CSE to develop an SCWT language use inventory to address the above research gaps. A total of 358 high school students were asked to complete the questionnaire, of which 277 valid responses were analyzed. Exploratory factor analysis(EFA) on the CSE-based questionnaire revealed the presence of six factors, namely language correctness, language variety, task planning, connecting-and-generating, selecting-andmining, and organizing. The strategy of connecting-and-generating was the only significant predictor of the learners’ SCWT scores. The paper also discusses the findings relating to the SCWT rating and other integrated writing tasks.
文摘Based on the researches of language transfer,contrastive analysis and error analysis,this paper tries to investigate the negative transfer of Chinese on Chinese students'English writings from the perspective of syntax.During one and a half months'teaching practice in Shannxi Hanzhong No.1 Middle School,the author lived through the real teaching process and found that there were lots of problems in students'English writings.The author makes a contrastive study of the different characteristics existing in Chinese and English languag es at the level of syntax,and analyses the typical syntactic errors appearing in the 60 students'English compositions collected from one or dinary class.These syntactic errors are caused by the negative transfer of Chinese.The purpose of the investigation is to study in what pat tern students have been influenced by Chinese in their English writings.Based on the findings and analysis of the mother tongue transfer on English writings,some implications are also provided in order to help minimize or eliminate the interference of negative transfer of the Chinese in students'English writings and improve the teaching and learning of English.
文摘We have made a clerical error in Table 1 on the page of 239, Volume 23, No.4 of Journal of Medical Colleges of PLA (the article is entitled as Expression and role of AQP1 in cervical squamous carcinoma
文摘To editorial board of Acta Mathematica Scientia(Acta MS) I was shocked when I was informed that the paper entitled"Eigenvalue Problem for the Laplacian Equations"by Shao Zhiqiang and Hong Jiaxing appeared in Acta MS(2007)Series B,no 2.For the past 15 years,I have not had any contact with Mr.Shao Zhiqiang and I have
基金Sponsored by “Twelfth Five-year Plan” Program of Guangdong Provincial Philosophy and Social Sciences(GD15XLS07)
文摘Western travel writings about China provided material driving and theoretical guidance for the Age of Discovery, and became the main spiritual motive of the Westerners voyage to the East. In the Age of Discovery, the image of China in the eyes of Western envoys, merchants and missionaries begun to fade away from traditional mythological and psychedelic colors, and the image of cultural elements such as material, spirit and history become clear. These Western travelers tried to shape the image of China as a state of civilization and wisdom, a state of moral order, and a state of wealth and power. On the basis of the continued description of the kingship and wealth of the Middle Ages, they constructed an overall image of China as a powerful state of civilization and wealth, thus forming a new frame of reference for cognition of China.
文摘Aims andscope of the Journal.Medical Journal of Chinese People's Liberation Army(Med J Chin PLA)is a multiple-subjects medical periodical published by the People's Military Medical Press,under the auspice of Department of Health,General Logistics Department of PLA,and it
文摘Aims and scope of the Journal. Medical Journal of Chinese People’s Liberation Army (Med J Chin PLA) is a multiple-subjects medical periodical published by the People’s Military Medical Press, under the auspice of Department of Health, General Logistics Department of PLA, and it is issued domestically and abroad. Med J Chin PLA has become one of the source journals of statistics in Chinese Scientific Thesis and Chinese Scientific Quotation Database, the key periodical of multiple-subject medical journals, and is a prize journal of National Periodical Award and one of the Top Hundred Periodicals in China. Med J Chin PLA is issued monthly. Its permanent sections include Expert Forum, Research on Special Topics, Medical Treatises, Experimental Research, Clinical Research, Technology and Methodology, Discussion of Knotty Cases (Pathology), Reviews, Military Medical Sciences, News in Medicine etc. Manuscripts sent by both domestic and overseas writers are welcome. Contribution of reviews is usually invited by the Editors, but recommendations for topics and authors are welcomed.
文摘Aims andscope of the Journal .Medical Journal of Chinese People’s Liberation Army (Med J Chin PLA) is a multiple-subjects medical periodical published by the People’s Military Medical Press,under the auspice of Department ofHealth, General Logistics Department of PLA,andit is issued
文摘Academic writings, whether they are BA dissertations or semester papers, are important carriers of one＇s ideas and findings of their own study and research spheres. In academic papers, the most important part is the choice of topics which determines the macro direction of the paper. Important as it is, it is difficult for the English majors to choose the most appropriate topics with idea-invested thesis statements instead of some factual statements. Therefore, in order to make clear of the status quo and underlying obstacles of topic choosing, this paper is to study on 98 samples from China University of Political Science and Law＇s junior English majors. By observing and analyzing their writings, the paper intends to fred out some possible and accessible methods to improve English majors＇ academic writing and offer some insights for teachers to make some adjustments in accordance with the status quo.
