The strict and high-standard requirements for the safety and stability ofmajor engineering systems make it a tough challenge for large-scale finite element modal analysis.At the same time,realizing the systematic anal...The strict and high-standard requirements for the safety and stability ofmajor engineering systems make it a tough challenge for large-scale finite element modal analysis.At the same time,realizing the systematic analysis of the entire large structure of these engineering systems is extremely meaningful in practice.This article proposes a multilevel hierarchical parallel algorithm for large-scale finite element modal analysis to reduce the parallel computational efficiency loss when using heterogeneous multicore distributed storage computers in solving large-scale finite element modal analysis.Based on two-level partitioning and four-transformation strategies,the proposed algorithm not only improves the memory access rate through the sparsely distributed storage of a large amount of data but also reduces the solution time by reducing the scale of the generalized characteristic equation(GCEs).Moreover,a multilevel hierarchical parallelization approach is introduced during the computational procedure to enable the separation of the communication of inter-nodes,intra-nodes,heterogeneous core groups(HCGs),and inside HCGs through mapping computing tasks to various hardware layers.This method can efficiently achieve load balancing at different layers and significantly improve the communication rate through hierarchical communication.Therefore,it can enhance the efficiency of parallel computing of large-scale finite element modal analysis by fully exploiting the architecture characteristics of heterogeneous multicore clusters.Finally,typical numerical experiments were used to validate the correctness and efficiency of the proposedmethod.Then a parallel modal analysis example of the cross-river tunnel with over ten million degrees of freedom(DOFs)was performed,and ten-thousand core processors were applied to verify the feasibility of the algorithm.展开更多
A new type of vibration structure (i.e. supporting system, called swing frame cus- tomarily) of vertical dynamic balancing machine has been designed, which is based on an analysis for the swing frame of a traditiona...A new type of vibration structure (i.e. supporting system, called swing frame cus- tomarily) of vertical dynamic balancing machine has been designed, which is based on an analysis for the swing frame of a traditional double-plane vertical dynamic balancing machine. The static unbalance and couple unbalance can be e?ectively separated by using the new dynamic balancing machine with the new swing frame. By building the dynamics model, the advantages of the new structure are discussed in detail. The modal and harmonic response are analyzed by using the ANSYS7.0. By comparing the ?nite element modal analysis with the experimental modal analy- sis, the natural frequencies and vibration modes are found. There are many spring boards in the new swing frame. Their sti?nesses are di?erent and assorted with each other. Furthermore, there are three sensors on the measuring points. Therefore, the new dynamic balancing machine can measure static unbalance and coupling unbalance directly, and the interaction between them is faint. The result shows that the new vertical dynamic balancing machine is suitable for inertial measurement of ?ying objects, and can overcome the shortcomings of traditional double-plane vertical dynamic balancing machines, which the e?ect of plane-separation is inferior. The vertical dynamic balancing machine with the new vibration structure can ?nd wide application in the future. The modelling and analysis of the new vibration structure will provide theoretical basis and practical experience for designing new-type vertical dynamic balancing machines.展开更多
Metabolic modeling and machine learning(ML)are crucial components of the evolving next-generation tools in systems and synthetic biology,aiming to unravel the intricate relationship between genotype,phenotype,and the ...Metabolic modeling and machine learning(ML)are crucial components of the evolving next-generation tools in systems and synthetic biology,aiming to unravel the intricate relationship between genotype,phenotype,and the environment.Nonetheless,the comprehensive exploration of integrating these two frameworks,and fully harnessing the potential of fluxomic data,remains an unexplored territory.In this study,we present,rigorously evaluate,and compare ML-based techniques for data integration.The hybrid model revealed that the overexpression of six target genes and the knockout of seven target genes contribute to enhanced ethanol production.Specifically,we investigated the influence of succinate dehydrogenase(SDH)on ethanol biosynthesis in Saccharomyces cerevisiae through shake flask experiments.The findings indicate a noticeable increase in ethanol yield,ranging from 6%to 10%,in SDH subunit gene knockout strains compared to the wild-type strain.Moreover,in pursuit of a high-yielding strain for ethanol production,dual-gene deletion experiments were conducted targeting glycerol-3-phosphate dehydrogenase(GPD)and SDH.The results unequivocally demonstrate significant enhancements in ethanol production for the engineered strains Δsdh4Δgpd1,Δsdh5Δgpd1,Δsdh6Δgpd1,Δsdh4Δgpd2,Δsdh5Δgpd2,and Δsdh6Δgpd2,with improvements of 21.6%,27.9%,and 22.7%,respectively.Overall,the results highlighted that integrating mechanistic flux features substantially improves the prediction of gene knockout strains not accounted for in metabolic reconstructions.In addition,the finding in this study delivers valuable tools for comprehending and manipulating intricate phenotypes,thereby enhancing prediction accuracy and facilitating deeper insights into mechanistic aspects within the field of synthetic biology.展开更多
A new type of vibration structure of vertical dynamic balancing machine isdesigned, which is based on the analysis for swing frame of a traditional vertical dynamic balancingmachine. The static unbalance and couple un...A new type of vibration structure of vertical dynamic balancing machine isdesigned, which is based on the analysis for swing frame of a traditional vertical dynamic balancingmachine. The static unbalance and couple unbalance can be separated effectively by using the newmachine with the new swing frame. By building the dynamics model, the advantages of the newstructure are discussed in detail. The modal and harmonic response are analyzed by using theANSYS7.0. By comparing the finite element modal analysis with the experimental modal analysis, thenatural frequencies and vibration modes are found out. There are many spring boards in the new swingframe. Their stiffness is different and assort with each other. Furthermore, there are threesensors on the measurement points. Therefore, the new dynamic balancing machine can measure thestatic unbalance and couple unbalance directly, and the influence between them is faint. The newstructure has the function of belt-strain compensation to improve the measurement precision. Thepractical result indicates that the new vertical dynamic balancing machine is suitable for inertialmeasurement of flying objects, and can overcome the shortcomings of traditional double-planevertical dynamic balancing machines. The vertical dynamic balancing machine with the new vibrationstructure can be widely used in the future applications. The modeling and analysis of the newvibration structure provide theoretic instruction and practical experience for designing new type ofvertical dynamic balancing machines. Based on the design principles such as stiffness-matching,frequency-adjacence and strain-compensation and so on, various new type of vibration structures canbe designed.展开更多
The mechanical balance process is the key process to eliminate the quadrature error and improve the performance of the cupped wave gyro. The conventional mechanical balance method for cupped wave gyro based on cup-wal...The mechanical balance process is the key process to eliminate the quadrature error and improve the performance of the cupped wave gyro. The conventional mechanical balance method for cupped wave gyro based on cup-wall trimming requires high control accuracy of trimming quantity, which increases the production cost and decreases the fabrication efficiency in large extent. However, it is hard to reach the high balance accuracy with the natural frequency split of mHz grade by using the conventional method. In this paper, the lumped mass dynamic model of the cupped wave gyro is built by discretization method, and the effects of different position trimming on the natural frequency are analyzed. It is pointed out that trimming off a tiny quantity of material from cup-wall causes large variation of the natural frequency is the main reason for the low accuracy of the conventional mechanical balance method. Then, a precision balance method for cupped wave gyro based on cup-bottom trimming is presented and the entire procedures of this method are given. The static balance process and dynamic balance process of the precision balance method are simulated by the finite element software. The simulation result shows that the precision balance method based on cup-bottom trimming brings less additional natural frequency split in the static balance process, minimizes the natural frequency split to mHz grade and rectify the angle of mode offset to 0.1° grade in the dynamic balance process, furthermore, the method decreases the requirement for control accuracy of trimming quantity evidently. The research work provides references for structure optimization design and balance process plan of the cupped wave gyro.展开更多
Imbalance vibration is a typical failure mode of rotational machines and has significant negative effects on the efficiency,accuracy,and service life of equipment.To automatically reduce the imbalance vibration during...Imbalance vibration is a typical failure mode of rotational machines and has significant negative effects on the efficiency,accuracy,and service life of equipment.To automatically reduce the imbalance vibration during the operational process,different types of active balancing actuators have been designed and widely applied in actual production.However,the existing electromagnetic-ring active balancing actuator is designed based on an axial excitation structure which can cause structural instability and has low electromagnetic driving efficiency.In this paper,a novel radial excitation structure and the working principle of an electromagnetic-ring active balancing actuator with a combined driving strategy are presented in detail.Then,based on a finite element model,the performance parameters of the actuator are analyzed,and reasonable design parameters are obtained.Self-locking torque measurements and comparative static and dynamic experiments are performed to validate the self-locking torque and driving efficiency of the actuator.The results indicate that this novel active balancing actuator has sufficient self-locking torque,achieves normal step rotation at 2000 r/min,and reduces the driving voltage by 12.5%.The proposed novel balancing actuator using radial excitation and a combination of permanent magnets and soft-iron blocks has improved electromagnetic efficiency and a more stable and compact structure.展开更多
基金supported by the National Natural Science Foundation of China(Grant No.11772192).
文摘The strict and high-standard requirements for the safety and stability ofmajor engineering systems make it a tough challenge for large-scale finite element modal analysis.At the same time,realizing the systematic analysis of the entire large structure of these engineering systems is extremely meaningful in practice.This article proposes a multilevel hierarchical parallel algorithm for large-scale finite element modal analysis to reduce the parallel computational efficiency loss when using heterogeneous multicore distributed storage computers in solving large-scale finite element modal analysis.Based on two-level partitioning and four-transformation strategies,the proposed algorithm not only improves the memory access rate through the sparsely distributed storage of a large amount of data but also reduces the solution time by reducing the scale of the generalized characteristic equation(GCEs).Moreover,a multilevel hierarchical parallelization approach is introduced during the computational procedure to enable the separation of the communication of inter-nodes,intra-nodes,heterogeneous core groups(HCGs),and inside HCGs through mapping computing tasks to various hardware layers.This method can efficiently achieve load balancing at different layers and significantly improve the communication rate through hierarchical communication.Therefore,it can enhance the efficiency of parallel computing of large-scale finite element modal analysis by fully exploiting the architecture characteristics of heterogeneous multicore clusters.Finally,typical numerical experiments were used to validate the correctness and efficiency of the proposedmethod.Then a parallel modal analysis example of the cross-river tunnel with over ten million degrees of freedom(DOFs)was performed,and ten-thousand core processors were applied to verify the feasibility of the algorithm.
基金Project supported by the National Natural Science Foundation of China (No.10176011).
文摘A new type of vibration structure (i.e. supporting system, called swing frame cus- tomarily) of vertical dynamic balancing machine has been designed, which is based on an analysis for the swing frame of a traditional double-plane vertical dynamic balancing machine. The static unbalance and couple unbalance can be e?ectively separated by using the new dynamic balancing machine with the new swing frame. By building the dynamics model, the advantages of the new structure are discussed in detail. The modal and harmonic response are analyzed by using the ANSYS7.0. By comparing the ?nite element modal analysis with the experimental modal analy- sis, the natural frequencies and vibration modes are found. There are many spring boards in the new swing frame. Their sti?nesses are di?erent and assorted with each other. Furthermore, there are three sensors on the measuring points. Therefore, the new dynamic balancing machine can measure static unbalance and coupling unbalance directly, and the interaction between them is faint. The result shows that the new vertical dynamic balancing machine is suitable for inertial measurement of ?ying objects, and can overcome the shortcomings of traditional double-plane vertical dynamic balancing machines, which the e?ect of plane-separation is inferior. The vertical dynamic balancing machine with the new vibration structure can ?nd wide application in the future. The modelling and analysis of the new vibration structure will provide theoretical basis and practical experience for designing new-type vertical dynamic balancing machines.
基金financially supported by the National Natural Science Foundation of China(Grant NO.32071461)the National Key Research and Development Program of China(Grant NO.2019YFA0904300).
文摘Metabolic modeling and machine learning(ML)are crucial components of the evolving next-generation tools in systems and synthetic biology,aiming to unravel the intricate relationship between genotype,phenotype,and the environment.Nonetheless,the comprehensive exploration of integrating these two frameworks,and fully harnessing the potential of fluxomic data,remains an unexplored territory.In this study,we present,rigorously evaluate,and compare ML-based techniques for data integration.The hybrid model revealed that the overexpression of six target genes and the knockout of seven target genes contribute to enhanced ethanol production.Specifically,we investigated the influence of succinate dehydrogenase(SDH)on ethanol biosynthesis in Saccharomyces cerevisiae through shake flask experiments.The findings indicate a noticeable increase in ethanol yield,ranging from 6%to 10%,in SDH subunit gene knockout strains compared to the wild-type strain.Moreover,in pursuit of a high-yielding strain for ethanol production,dual-gene deletion experiments were conducted targeting glycerol-3-phosphate dehydrogenase(GPD)and SDH.The results unequivocally demonstrate significant enhancements in ethanol production for the engineered strains Δsdh4Δgpd1,Δsdh5Δgpd1,Δsdh6Δgpd1,Δsdh4Δgpd2,Δsdh5Δgpd2,and Δsdh6Δgpd2,with improvements of 21.6%,27.9%,and 22.7%,respectively.Overall,the results highlighted that integrating mechanistic flux features substantially improves the prediction of gene knockout strains not accounted for in metabolic reconstructions.In addition,the finding in this study delivers valuable tools for comprehending and manipulating intricate phenotypes,thereby enhancing prediction accuracy and facilitating deeper insights into mechanistic aspects within the field of synthetic biology.
文摘A new type of vibration structure of vertical dynamic balancing machine isdesigned, which is based on the analysis for swing frame of a traditional vertical dynamic balancingmachine. The static unbalance and couple unbalance can be separated effectively by using the newmachine with the new swing frame. By building the dynamics model, the advantages of the newstructure are discussed in detail. The modal and harmonic response are analyzed by using theANSYS7.0. By comparing the finite element modal analysis with the experimental modal analysis, thenatural frequencies and vibration modes are found out. There are many spring boards in the new swingframe. Their stiffness is different and assort with each other. Furthermore, there are threesensors on the measurement points. Therefore, the new dynamic balancing machine can measure thestatic unbalance and couple unbalance directly, and the influence between them is faint. The newstructure has the function of belt-strain compensation to improve the measurement precision. Thepractical result indicates that the new vertical dynamic balancing machine is suitable for inertialmeasurement of flying objects, and can overcome the shortcomings of traditional double-planevertical dynamic balancing machines. The vertical dynamic balancing machine with the new vibrationstructure can be widely used in the future applications. The modeling and analysis of the newvibration structure provide theoretic instruction and practical experience for designing new type ofvertical dynamic balancing machines. Based on the design principles such as stiffness-matching,frequency-adjacence and strain-compensation and so on, various new type of vibration structures canbe designed.
基金supported by National Natural Science Foundation of China (Grant No. 51005239)
文摘The mechanical balance process is the key process to eliminate the quadrature error and improve the performance of the cupped wave gyro. The conventional mechanical balance method for cupped wave gyro based on cup-wall trimming requires high control accuracy of trimming quantity, which increases the production cost and decreases the fabrication efficiency in large extent. However, it is hard to reach the high balance accuracy with the natural frequency split of mHz grade by using the conventional method. In this paper, the lumped mass dynamic model of the cupped wave gyro is built by discretization method, and the effects of different position trimming on the natural frequency are analyzed. It is pointed out that trimming off a tiny quantity of material from cup-wall causes large variation of the natural frequency is the main reason for the low accuracy of the conventional mechanical balance method. Then, a precision balance method for cupped wave gyro based on cup-bottom trimming is presented and the entire procedures of this method are given. The static balance process and dynamic balance process of the precision balance method are simulated by the finite element software. The simulation result shows that the precision balance method based on cup-bottom trimming brings less additional natural frequency split in the static balance process, minimizes the natural frequency split to mHz grade and rectify the angle of mode offset to 0.1° grade in the dynamic balance process, furthermore, the method decreases the requirement for control accuracy of trimming quantity evidently. The research work provides references for structure optimization design and balance process plan of the cupped wave gyro.
基金Supported by National Natural Scie nce Foun dation of China(Grant No.51875031)Youth Backb one Personal Project of Beijing(Grant No.2017000020124G018).
文摘Imbalance vibration is a typical failure mode of rotational machines and has significant negative effects on the efficiency,accuracy,and service life of equipment.To automatically reduce the imbalance vibration during the operational process,different types of active balancing actuators have been designed and widely applied in actual production.However,the existing electromagnetic-ring active balancing actuator is designed based on an axial excitation structure which can cause structural instability and has low electromagnetic driving efficiency.In this paper,a novel radial excitation structure and the working principle of an electromagnetic-ring active balancing actuator with a combined driving strategy are presented in detail.Then,based on a finite element model,the performance parameters of the actuator are analyzed,and reasonable design parameters are obtained.Self-locking torque measurements and comparative static and dynamic experiments are performed to validate the self-locking torque and driving efficiency of the actuator.The results indicate that this novel active balancing actuator has sufficient self-locking torque,achieves normal step rotation at 2000 r/min,and reduces the driving voltage by 12.5%.The proposed novel balancing actuator using radial excitation and a combination of permanent magnets and soft-iron blocks has improved electromagnetic efficiency and a more stable and compact structure.