Nanomaterial-assisted wearable glucose biosensors for noninvasive real-time monitoring:Pioneering point-of-care and beyond

This review explores glucose monitoring and management strategies,emphasizing the need for reliable and userfriendly wearable sensors that are the next generation of sensors for continuous glucose detection.In addition,examines key strategies for designing glucose sensors that are multi-functional,reliable,and cost-effective in a variety of contexts.The unique features of effective diabetes management technology are highlighted,with a focus on using nano/biosensor devices that can quickly and accurately detect glucose levels in the blood,improving patient treatment and control of potential diabetes-related infections.The potential of next-generation wearable and touch-sensitive nano biomedical sensor engineering designs for providing full control in assessing implantable,continuous glucose monitoring is also explored.The challenges of standardizing drug or insulin delivery doses,low-cost,real-time detection of increased blood sugar levels in diabetics,and early digital health awareness controls for the adverse effects of injectable medication are identified as unmet needs.Also,the market for biosensors is expected to expand significantly due to the rising need for portable diagnostic equipment and an ever-increasing diabetic population.The paper concludes by emphasizing the need for further research and development of glucose biosensors to meet the stringent requirements for sensitivity and specificity imposed by clinical diagnostics while being cost-effective,stable,and durable.

Design and Construction of Automatic Monitoring System for Open-pit Coal Mine Slopes

[Objectives]To monitor the stability of open-pit coal mine slopes in real time and ensure the safety of coal mine production.[Methods]The automatic monitoring system of coal mine slope was explored in depth,and the core functions of the system were designed comprehensively.According to the design function of the automatic monitoring system,the slope automatic monitoring system was constructed.Besides,in accordance with the actual situation of the slope,the monitoring frequency of slopes was set scientifically,and the key indicators such as rainfall,deep displacement and surface displacement of the slopes were monitored in an all-round and multi-angle way.[Results]During the monitoring period,the overall condition of the slope remained good,and no landslides or other geological disasters occurred.At the same time,the overall rainfall in the slope area remained low.In terms of monitoring data,the horizontal displacement and settlement of the slopes increased first and then tended to be stable.Specifically,the maximum horizontal displacement during the monitoring period was 22.74 mm,while the maximum settlement was 18.65 mm.[Conclusions]The automatic slope monitoring system has obtained remarkable achievements in practical application.It not only improves the accuracy and efficiency of slope stability monitoring,but also provides valuable reference experience for similar projects.

Real-Time Monitoring Method for Cow Rumination Behavior Based on Edge Computing and Improved MobileNet v3

[Objective]Real-time monitoring of cow ruminant behavior is of paramount importance for promptly obtaining relevant information about cow health and predicting cow diseases.Currently,various strategies have been proposed for monitoring cow ruminant behavior,including video surveillance,sound recognition,and sensor monitoring methods.How‐ever,the application of edge device gives rise to the issue of inadequate real-time performance.To reduce the volume of data transmission and cloud computing workload while achieving real-time monitoring of dairy cow rumination behavior,a real-time monitoring method was proposed for cow ruminant behavior based on edge computing.[Methods]Autono‐mously designed edge devices were utilized to collect and process six-axis acceleration signals from cows in real-time.Based on these six-axis data,two distinct strategies,federated edge intelligence and split edge intelligence,were investigat‐ed for the real-time recognition of cow ruminant behavior.Focused on the real-time recognition method for cow ruminant behavior leveraging federated edge intelligence,the CA-MobileNet v3 network was proposed by enhancing the MobileNet v3 network with a collaborative attention mechanism.Additionally,a federated edge intelligence model was designed uti‐lizing the CA-MobileNet v3 network and the FedAvg federated aggregation algorithm.In the study on split edge intelli‐gence,a split edge intelligence model named MobileNet-LSTM was designed by integrating the MobileNet v3 network with a fusion collaborative attention mechanism and the Bi-LSTM network.[Results and Discussions]Through compara‐tive experiments with MobileNet v3 and MobileNet-LSTM,the federated edge intelligence model based on CA-Mo‐bileNet v3 achieved an average Precision rate,Recall rate,F1-Score,Specificity,and Accuracy of 97.1%,97.9%,97.5%,98.3%,and 98.2%,respectively,yielding the best recognition performance.[Conclusions]It is provided a real-time and effective method for monitoring cow ruminant behavior,and the proposed federated edge intelligence model can be ap‐plied in practical settings.

Automatic Monitoring System for 3-D Deformation of Crustal Fault Based on Laser and Machine Vision

An automatic monitoring method of the 3-D deformation is presented for crustal fault based on laser and machine vision. The laser source and screen are independently set up in the headwall and footwall, the collimated laser beam creates a circular spot on the screen, meanwhile, the industrial camera captures the tiny deformation of the crustal fault by monitoring the change of the spot position. This method significantly reduces the cost of equipment and labor, provides daily sampling to ensure high continuity of data. A prototype of the automatic monitoring system is developed, and a repeatability test indicates that the error of spot jitter can be minimized by consecutive samples. Meanwhile, the environmental correction model is determined to ensure that environmental changes do not disturb the system. Furthermore, the automatic monitoring system has been applied at the deformation monitoring station(KJX02) of China Beishan underground research laboratory, where continuous deformation monitoring is underway.

Design of Intelligent Window Automatic Monitoring System Based on Microcontroller Control

To ensure the safety of residents’lives and property by using automatic opening and closing of ordinary windows,this article designs an intelligent window automatic monitoring system.The article proposes a software and hardware design scheme for the system,which comprises a microcontroller control module,temperature and humidity detection module,harmful gas detection module,rainfall detection module,human thermal radiation induction module,Organic Light-Emitting Diode(OLED)display module,stepper motor drive module,Wi-Fi communication module,etc.Users use this system to monitor environmental data such as temperature,humidity,rainfall,harmful gas concentrations,and human health.Users can control the opening and closing of windows through manual,microcontroller,and mobile application(app)remote methods,providing users with a more convenient,comfortable,and safe living environment.

Real-Time Monitoring of Meteorological Data at In-Situ GCW Remediation Sites

To optimize the self-organization network, self-adaptation, real-time monitoring, remote management capability, and equipment reuse level of the meteorological station supporting the portable groundwater circulation wells, and to provide real-time and effective technical services and environmental data support for groundwater remediation, a real-time monitoring system design of the meteorological station supporting the portable groundwater circulation wells based on the existing equipment is proposed. A variety of environmental element information is collected and transmitted to the embedded web server by the intelligent weather transmitter, and then processed by the algorithm and stored internally, displayed locally, and published on the web. The system monitoring algorithm and user interface are designed in the CNWSCADA development environment to realize real-time processing and analysis of environmental data and monitoring, control, management, and maintenance of the system status. The PLC-controlled photovoltaic power generating panels and lithium battery packs are in line with the concept of energy saving and emission reduction, and at the same time, as an emergency power supply to guarantee the safety of equipment and data when the utility power fails to meet the requirements. The experiment proves that the system has the characteristics of remote control, real-time interaction, simple station deployment, reliable operation, convenient maintenance, and green environment protection, which is conducive to improving the comprehensive utilization efficiency of various types of environmental information and providing reliable data support, theoretical basis and guidance suggestions for the research of groundwater remediation technology and its disciplines, and the research and development of the movable groundwater cycling well monitoring system.

Real-time prediction of mechanical behaviors of underwater shield tunnel structure using machine learning method based on structural health monitoring data

Predicting the mechanical behaviors of structure and perceiving the anomalies in advance are essential to ensuring the safe operation of infrastructures in the long run.In addition to the incomplete consideration of influencing factors,the prediction time scale of existing studies is rough.Therefore,this study focuses on the development of a real-time prediction model by coupling the spatio-temporal correlation with external load through autoencoder network(ATENet)based on structural health monitoring(SHM)data.An autoencoder mechanism is performed to acquire the high-level representation of raw monitoring data at different spatial positions,and the recurrent neural network is applied to understanding the temporal correlation from the time series.Then,the obtained temporal-spatial information is coupled with dynamic loads through a fully connected layer to predict structural performance in next 12 h.As a case study,the proposed model is formulated on the SHM data collected from a representative underwater shield tunnel.The robustness study is carried out to verify the reliability and the prediction capability of the proposed model.Finally,the ATENet model is compared with some typical models,and the results indicate that it has the best performance.ATENet model is of great value to predict the realtime evolution trend of tunnel structure.

Real-Time, Automatic and Wireless Bridge Monitoring System Based on MEMS Technology

Currently, the monitoring of bridges in China heavily relies on manual operation, which has several major problems. It generally takes a very long time to complete an inspection process on bridges. The manual data is sometimes unreliable or even wrong in the case of careless operation. The inspection activity itself is dangerous for inspectors, e.g., bridges are located in the sea or river. Some semi-automatic monitoring methods are recently employed, but they are either very expensive or do not work properly. Therefore, the traditional bridge monitoring process becomes an increasing challenge for bridge operators. In this paper, a real-time and automatic bridge monitoring system is presented to meet the bridge monitoring needs, and MEMS （Micro Electro Mechanical Systems） are the key building block in this system. By using the MEMS-based sensors, it is much more efficient and accurate in monitoring bridges with the measurement of inclination, acceleration, displacement, moisture, temperature, stress and other data.

Real-time Monitoring of Subsea Gas Pipelines,Offshore Platforms,and Ship Inspection Scores Using an Automatic Identification System

The aim of this research is to develop an algorithm and application that can perform real-time monitoring of the safety operation of offshore platforms and subsea gas pipelines as well as determine the need for ship inspection using data obtained from automatic identification system(AIS).The research also focuses on the integration of shipping database,AIS data,and others to develop a prototype for designing a real-time monitoring system of offshore platforms and pipelines.A simple concept is used in the development of this prototype,which is achieved by using an overlaying map that outlines the coordinates of the offshore platform and subsea gas pipeline with the ship’s coordinates(longitude/latitude)as detected by AIS.Using such information,we can then build an early warning system(EWS)relayed through short message service(SMS),email,or other means when the ship enters the restricted and exclusion zone of platforms and pipelines.The ship inspection system is developed by combining several attributes.Then,decision analysis software is employed to prioritize the vessel’s four attributes,including ship age,ship type,classification,and flag state.Results show that the EWS can increase the safety level of offshore platforms and pipelines,as well as the efficient use of patrol boats in monitoring the safety of the facilities.Meanwhile,ship inspection enables the port to prioritize the ship to be inspected in accordance with the priority ranking inspection score.

Towards Cache-Assisted Hierarchical Detection for Real-Time Health Data Monitoring in IoHT

Real-time health data monitoring is pivotal for bolstering road services’safety,intelligence,and efficiency within the Internet of Health Things(IoHT)framework.Yet,delays in data retrieval can markedly hinder the efficacy of big data awareness detection systems.We advocate for a collaborative caching approach involving edge devices and cloud networks to combat this.This strategy is devised to streamline the data retrieval path,subsequently diminishing network strain.Crafting an adept cache processing scheme poses its own set of challenges,especially given the transient nature of monitoring data and the imperative for swift data transmission,intertwined with resource allocation tactics.This paper unveils a novel mobile healthcare solution that harnesses the power of our collaborative caching approach,facilitating nuanced health monitoring via edge devices.The system capitalizes on cloud computing for intricate health data analytics,especially in pinpointing health anomalies.Given the dynamic locational shifts and possible connection disruptions,we have architected a hierarchical detection system,particularly during crises.This system caches data efficiently and incorporates a detection utility to assess data freshness and potential lag in response times.Furthermore,we introduce the Cache-Assisted Real-Time Detection(CARD)model,crafted to optimize utility.Addressing the inherent complexity of the NP-hard CARD model,we have championed a greedy algorithm as a solution.Simulations reveal that our collaborative caching technique markedly elevates the Cache Hit Ratio(CHR)and data freshness,outshining its contemporaneous benchmark algorithms.The empirical results underscore the strength and efficiency of our innovative IoHT-based health monitoring solution.To encapsulate,this paper tackles the nuances of real-time health data monitoring in the IoHT landscape,presenting a joint edge-cloud caching strategy paired with a hierarchical detection system.Our methodology yields enhanced cache efficiency and data freshness.The corroborative numerical data accentuates the feasibility and relevance of our model,casting a beacon for the future trajectory of real-time health data monitoring systems.

Prototyping low-cost automatic weather stations for natural disaster monitoring

Weather events put human lives at risk mostly when people might occupy areas susceptible to natural disasters.Deploying Professional Weather Stations(PWS)in vulnerable areas is key for monitoring weather with reliable measurements.However,such professional instrumentation is notably expensive while remote sensing from a number of stations is paramount.This imposes challenges on the large-scale weather station deployment for broad monitoring from large observation networks such as in Cemaden—The Brazilian National Center for Monitoring and Early Warning of Natural Disasters.In this context,in this paper,we propose a Low-Cost Automatic Weather Station(LCAWS)system developed from Commercial Off-The-Shelf(COTS)and open-source Internet of Things(IoT)technologies,which provides measurements as reliable as a reference PWS for natural disaster monitoring.When being automatic,LCAWS is a stand-alone photovoltaic system connected wirelessly to the Internet in order to provide real-time reliable end-to-end weather measurements.To achieve data reliability,we propose an intelligent sensor calibration method to correct measures.From a 30-day uninterrupted observation with sampling in minute resolution,we show that the calibrated LCAWS sensors have no statistically significant differences from the PWS measurements.As such,LCAWS has opened opportunities for reducing maintenance costs in Cemaden's observational network.

Pore-pressure and stress-coupled creep behavior in deep coal:Insights from real-time NMR analysis

Understanding the variations in microscopic pore-fracture structures(MPFS) during coal creep under pore pressure and stress coupling is crucial for coal mining and effective gas treatment. In this manuscript, a triaxial creep test on deep coal at various pore pressures using a test system that combines in-situ mechanical loading with real-time nuclear magnetic resonance(NMR) detection was conducted.Full-scale quantitative characterization, online real-time detection, and visualization of MPFS during coal creep influenced by pore pressure and stress coupling were performed using NMR and NMR imaging(NMRI) techniques. The results revealed that seepage pores and microfractures(SPM) undergo the most significant changes during coal creep, with creep failure gradually expanding from dense primary pore fractures. Pore pressure presence promotes MPFS development primarily by inhibiting SPM compression and encouraging adsorption pores(AP) to evolve into SPM. Coal enters the accelerated creep stage earlier at lower stress levels, resulting in more pronounced creep deformation. The connection between the micro and macro values was established, demonstrating that increased porosity at different pore pressures leads to a negative exponential decay of the viscosity coefficient. The Newton dashpot in the ideal viscoplastic body and the Burgers model was improved using NMR experimental results, and a creep model that considers pore pressure and stress coupling using variable-order fractional operators was developed. The model’s reasonableness was confirmed using creep experimental data. The damagestate adjustment factors ω and β were identified through a parameter sensitivity analysis to characterize the effect of pore pressure and stress coupling on the creep damage characteristics(size and degree of difficulty) of coal.

Semi-implantable device based on multiplexed microfilament electrode cluster for continuous monitoring of physiological ions

Modern medicine is increasingly interested in advanced sensors to detect and analyze biochemical indicators.Ion sensors based on potentiometric methods are a promising platform for monitoring physiological ions in biological subjects.Current semi-implantable devices are mainly based on single-parameter detection.Miniaturized semi-implantable electrodes for multiparameter sensing have more restrictions on the electrode size due to biocompatibility considerations,but reducing the electrode surface area could potentially limit electrode sensitivity.This study developed a semi-implantable device system comprising a multiplexed microfilament electrode cluster(MMEC)and a printed circuit board for real-time monitoring of intra-tissue K^(+),Ca^(2+),and Na^(+)concentrations.The electrode surface area was less important for the potentiometric sensing mechanism,suggesting the feasibility of using a tiny fiber-like electrode for potentiometric sensing.The MMEC device exhibited a broad linear response(K^(+):2–32 mmol/L;Ca^(2+):0.5–4 mmol/L;Na^(+):10–160 mmol/L),high sensitivity(about 20–45 mV/decade),temporal stability(>2weeks),and good selectivity(>80%)for the above ions.In vitro detection and in vivo subcutaneous and brain experiment results showed that the MMEC system exhibits good multi-ion monitoring performance in several complex environments.This work provides a platform for the continuous real-time monitoring of ion fluctuations in different situations and has implications for developing smart sensors to monitor human health.

Real-time Monitoring Scheme of Soil Moisture Content in Paddy Field

The monitoring of soil moisture content in paddy field is one of important parts and contents of regional soil moisture monitoring. But a good monitoring scheme hasn’t been established. A real-time monitoring scheme of soil moisture content in paddy field was put forward from two key links of soil moisture content monitoring and field water-layer monitoring. This scheme could meet the alternative monitoring requirements of soil moisture content in water layer and none-water layer. It had a good maneuverability and could provide references for practical work.

Development of an automatic monitoring system for rice light-trap pests based on machine vision

Monitring pest populations in paddy fields is important to effectively implement integrated pest management.Light traps are widely used to monitor field pests all over the world.Most conventional light traps still involve manual identification of target pests from lots of trapped insects,which is time-consuming,labor-intensive and error-prone,especially in pest peak periods.In this paper,we developed an automatic monitoring system for rice light-trap pests based on machine vision.This system is composed of an itelligent light trap,a computer or mobile phone client platform and a cloud server.The light trap firstly traps,kills and disperses insects,then collects images of trapped insects and sends each image to the cloud server.Five target pests in images are automatically identifed and counted by pest identification models loaded in the server.To avoid light-trap insects piling up,a vibration plate and a moving rotation conveyor belt are adopted to disperse these trapped insects.There was a close correlation(r=0.92)between our automatic and manual identification methods based on the daily pest number of one-year images from one light trap.Field experiments demonstrated the effectiveness and accuracy of our automatic light trap monitoring system.

Construction of multi-factor identification model for real-time monitoring and early warning of mine water inrush

As a new technical means that can detect abnormal signs of water inrush in advance and give an early warning,the automatic monitoring and early warning of water inrush in mines has been widely valued in recent years.Due to the many factors affecting water inrush and the complicated water inrush mechanism,many factors close to water inrush may have precursory abnormal changes.At present,the existing monitoring and early warning system mainly uses a few monitoring indicators such as groundwater level,water influx,and temperature,and performs water inrush early warning through the abnormal change of a single factor.However,there are relatively few multi-factor comprehensive early warning identification models.Based on the analysis of the abnormal changes of precursor factors in multiple water inrush cases,11 measurable and effective indicators including groundwater flow field,hydrochemical field and temperature field are proposed.Finally,taking Hengyuan coal mine as an example,6 indicators with long-term monitoring data sequences were selected to establish a single-index hierarchical early-warning recognition model,a multi-factor linear recognition model,and a comprehensive intelligent early-warning recognition model.The results show that the correct rate of early warning can reach 95.2%.

Stability and remote real-time monitoring of the slope slide body in the Luoshan mining area

Landslides have occurred frequently in the Luoshan mining area because of disordered mining.This paper discusses the landforms and physiognomy,hydro-meteorology,formation lithology,and geologic structure of the Luoshan mining area.It also describes the factors influencing the slope stability of landslide No.Ⅲ,determines the general parameters and typical section plane,analyzes the stress-strain state of the No.Ⅲ slope,and calculates its safety factors with FLAC3 D under saturated and natural conditions.Based on a stability analysis,a remote real-time monitoring system was applied to the No.Ⅲ slope,and these monitoring data were collected and analyzed.

A Real-Time System for Monitoring Distant Dynamic Displacement of Structures

Based on digital image processing technique, a real-time system is developed to monitor and detect the dynamic displacement of engineering structures. By processing pictures with a self-programmed software, the real-time coordinate of an object in a certain coordinate system can be obtained, and further dynamic displacement data and curve of the object can also be achieved. That is, automatic gathering and real-time processing of data can be carried out by this system simultaneously. For this system, first, an untouched monitoring technique is adopted, which can monitor or detect objects several to hundreds of meters apart; second, it has flexible installation condition and good monitoring precision of sub-millimeter degree; third, it is fit for dynamic, quasi-dynamic and static monitoring of large engineering structures. Through several tests and applications in large bridges, good reliability and dominance of the system is proved.

A wearable real-time telemonitoring electrocardiogram device compared with traditional Holter monitoring

Arrhythmias are very common in the healthy populations as well as patients with cardiovascular diseases.Among them,atrial fibrillation(AF)and malignant ventricular arrhythmias are usually associated with some clinical events.Early diagnosis of arrhythmias,particularly AF and ventricular arrhythmias,is very important for the treatment and prognosis of patients.Holter is a gold standard commonly recommended for noninvasive detection of paroxysmal arrhythmia.However,it has some shortcomings such as fixed detection timings,delayed report and inability of remote real-time detection.To deal with such problems,we designed and applied a new wearable 72-hour triple-lead H3-electrocardiogram(ECG)device with a remote cloud-based ECG platform and an expertsupporting system.In this study,31 patients were recruited and 24-hour synchronous ECG data by H3-ECG and Holter were recorded.In the H3-ECG group,ECG signals were transmitted using remote real-time modes,and confirmed reports were made by doctors in the remote expert-supporting system,while the traditional modes and detection systems were used in the Holter group.The results showed no significant differences between the two groups in 24-hour total heart rate(HR),averaged HR,maximum HR,minimum HR,premature atrial complexes(PACs)and premature ventricular complexes(PVCs)(P>0.05).The sensitivity and specificity of capture and remote automatic cardiac events detection of PACs,PVCs,and AF by H3-ECG were 93%and 99%,98%and 99%,94%and 98%,respectively.Therefore,the long-term limb triple-lead H3-ECG device can be utilized for domiciliary ECG self-monitoring and remote management of patients with common arrhythmia under medical supervision.

Real-Time Spreading Thickness Monitoring of High-core Rockfill Dam Based on K-nearest Neighbor Algorithm

During the storehouse surface rolling construction of a core rockfilldam, the spreading thickness of dam face is an important factor that affects the construction quality of the dam storehouse' rolling surface and the overallquality of the entire dam. Currently, the method used to monitor and controlspreading thickness during the dam construction process is artificialsampling check after spreading, which makes it difficult to monitor the entire dam storehouse surface. In this paper, we present an in-depth study based on real-time monitoring and controltheory of storehouse surface rolling construction and obtain the rolling compaction thickness by analyzing the construction track of the rolling machine. Comparatively, the traditionalmethod can only analyze the rolling thickness of the dam storehouse surface after it has been compacted and cannot determine the thickness of the dam storehouse surface in realtime. To solve these problems, our system monitors the construction progress of the leveling machine and employs a real-time spreading thickness monitoring modelbased on the K-nearest neighbor algorithm. Taking the LHK core rockfilldam in Southwest China as an example, we performed real-time monitoring for the spreading thickness and conducted real-time interactive queries regarding the spreading thickness. This approach provides a new method for controlling the spreading thickness of the core rockfilldam storehouse surface.