Oleum azadirachti consists of the oil obtained from dried seeds of Azadirachta indica A.Juss.(family:Meliaceae).Local names of Azadirachta indica A.Juss.are Abodua,aforo-oyinbo,anwe egyane,arista,azad dirakht,azadarak...Oleum azadirachti consists of the oil obtained from dried seeds of Azadirachta indica A.Juss.(family:Meliaceae).Local names of Azadirachta indica A.Juss.are Abodua,aforo-oyinbo,anwe egyane,arista,azad dirakht,azadarakht,azedarach and bead tree.Indigenous to India,and widely distributed in South and South-East Asia and cultivated in Africa,the South Pacific Islands,South and Central America and Australia,and in southern Florida and California,United States of America,it is a straight-boled deciduous tree,which is 6-25 m high.Bark is dark-brown,externally fissured with a buff inner surface and fibrous fracture,Leaves alternately arranged,pinnately compound and up to 40 cm long,and composed of 8-18 short-petiolate narrow-ovate,pointed and curved toothed leaflets,3-10 cm long and 1-4 cm wide arranged in alternate pairs.The major constituents are oxidized tetranortriterpenes including azadirachtin(azadirachtin A),azadiriadione,epoxyazadiradione,azadirone,nimbidin,nimbin,deacelylnimbin,salannin,gedunin,mahmoodin,17-hydroxydiradione and related derivatives.It is of various medicinal uses,such as a contraceptive for intravaginal use,a mosquito repellent,and treatment of vaginal infections,treatment of gastric ulcers,cardiovascular disease,malaria,rheumatism and skin disorders,external applications for treatment of septic wounds,ulcers and boils,treatment of allergic skin reactions,asthma,bruises,colic,conjunctivitis,dysmenorrhoea,fever,gout,headache,itching due to varicella,kidney stones,leukorrhoea,psoriasis,scabies,sprains and muscular pain,and wounds.It is also used as an emmenagogue.tonic,stomatic and vermicide.In conclusion,the plant oil had antifertility,antihyperglycaemic,anti-inflammatory,antimicrobial,antiviral,antiulcer,estrogenic,immune,contraceptive,autibacterial,insect repellent,and skin treatment effects.展开更多
基金Supported by a grant from advanced medical and dental(AMDI)/Universiti Sains Malaysia(USM)(FWA/IRB Registration No:00005528/00002294)
文摘Oleum azadirachti consists of the oil obtained from dried seeds of Azadirachta indica A.Juss.(family:Meliaceae).Local names of Azadirachta indica A.Juss.are Abodua,aforo-oyinbo,anwe egyane,arista,azad dirakht,azadarakht,azedarach and bead tree.Indigenous to India,and widely distributed in South and South-East Asia and cultivated in Africa,the South Pacific Islands,South and Central America and Australia,and in southern Florida and California,United States of America,it is a straight-boled deciduous tree,which is 6-25 m high.Bark is dark-brown,externally fissured with a buff inner surface and fibrous fracture,Leaves alternately arranged,pinnately compound and up to 40 cm long,and composed of 8-18 short-petiolate narrow-ovate,pointed and curved toothed leaflets,3-10 cm long and 1-4 cm wide arranged in alternate pairs.The major constituents are oxidized tetranortriterpenes including azadirachtin(azadirachtin A),azadiriadione,epoxyazadiradione,azadirone,nimbidin,nimbin,deacelylnimbin,salannin,gedunin,mahmoodin,17-hydroxydiradione and related derivatives.It is of various medicinal uses,such as a contraceptive for intravaginal use,a mosquito repellent,and treatment of vaginal infections,treatment of gastric ulcers,cardiovascular disease,malaria,rheumatism and skin disorders,external applications for treatment of septic wounds,ulcers and boils,treatment of allergic skin reactions,asthma,bruises,colic,conjunctivitis,dysmenorrhoea,fever,gout,headache,itching due to varicella,kidney stones,leukorrhoea,psoriasis,scabies,sprains and muscular pain,and wounds.It is also used as an emmenagogue.tonic,stomatic and vermicide.In conclusion,the plant oil had antifertility,antihyperglycaemic,anti-inflammatory,antimicrobial,antiviral,antiulcer,estrogenic,immune,contraceptive,autibacterial,insect repellent,and skin treatment effects.
