Nitrato\|terminated polyalkylene glycols were synthesized from nitrating glycols with nitric acid and sulfuric acid in methylene chloride. Then azido\|terminated polyalkylene glycols were prepared by a nucleophilic re...Nitrato\|terminated polyalkylene glycols were synthesized from nitrating glycols with nitric acid and sulfuric acid in methylene chloride. Then azido\|terminated polyalkylene glycols were prepared by a nucleophilic reaction of the nitrato\|terminated polyalkylene glycols with sodium azide in different phase transfer catalytic conditions. All synthesized polymers were characterized by \{\}\+1H\|MNR, FT\|IR, GPC and elemental analysis.展开更多
Functionalized aliphatic polyesters, especially those with pendent hydroxyl, carboxyl and amino groups, have attracted much research interest in recent years due to their perfect biocompatibility, biodegra-dability an...Functionalized aliphatic polyesters, especially those with pendent hydroxyl, carboxyl and amino groups, have attracted much research interest in recent years due to their perfect biocompatibility, biodegra-dability and reactivity. Copolymerization of lactide with functionalized cyclic carbonate monomers proved to be an efficient way to functionalize aliphatic polyesters. However, random co-polyesters with pendent amino groups were seldom reported. This article reported a facile way to prepare aliphatic polyesters with random pendant azido and amino groups via Click reaction.展开更多
Seventeen novel gem-difluoromethylene-containing 1,2,3-triazoles were synthesized by the click reaction of ethyl 2-azido-2,2-difluoroacetate and terminal alkynes in the presence of 10 mol% CuI.
文摘Nitrato\|terminated polyalkylene glycols were synthesized from nitrating glycols with nitric acid and sulfuric acid in methylene chloride. Then azido\|terminated polyalkylene glycols were prepared by a nucleophilic reaction of the nitrato\|terminated polyalkylene glycols with sodium azide in different phase transfer catalytic conditions. All synthesized polymers were characterized by \{\}\+1H\|MNR, FT\|IR, GPC and elemental analysis.
文摘Functionalized aliphatic polyesters, especially those with pendent hydroxyl, carboxyl and amino groups, have attracted much research interest in recent years due to their perfect biocompatibility, biodegra-dability and reactivity. Copolymerization of lactide with functionalized cyclic carbonate monomers proved to be an efficient way to functionalize aliphatic polyesters. However, random co-polyesters with pendent amino groups were seldom reported. This article reported a facile way to prepare aliphatic polyesters with random pendant azido and amino groups via Click reaction.
基金Project supported by the National Natural Science Foundation of China （No. 21072057）, the Key Project in the National Science ＆ Technology Pillar Program of China in the Twelfth Five-year Plan Period （No. 2011BAE06B05）, and the Shanghai Leading Academic Discipline Project （No. B507）.
文摘Seventeen novel gem-difluoromethylene-containing 1,2,3-triazoles were synthesized by the click reaction of ethyl 2-azido-2,2-difluoroacetate and terminal alkynes in the presence of 10 mol% CuI.
