The effects of minimally invasive surgery on the blood-brain barrier （BBB） of 30 patients with cerebral hemorrhage were investigated. Difference of the BBB index and serum MBP concentration were assessed in 15 cases...The effects of minimally invasive surgery on the blood-brain barrier （BBB） of 30 patients with cerebral hemorrhage were investigated. Difference of the BBB index and serum MBP concentration were assessed in 15 cases of conservative treatment group and 15 cases of minimally invasive surgery group. The BBB index in minimally invasive surgery group was significantly lower than in conservative treatment group （P〈0.05）, and the BBB index in the two treatment groups was significantly higher than in control group （P〈0.01）. Serum MBP concentration in minimally invasive surgery group was significantly lower than in conservative treatment group （P〈0.05）, and that in the two treatment groups was significantly higher than in control group （P〈0.01）. It was suggested the permeability of BBB in patients with cerebral hemorrhage was increased, and BBB index and serum MBP concentration in patients with cerebral hemorrhage were increased. Minimally invasive surgery can reduce the lesion of cytotoxicity to BBB and cerebral edema.展开更多
The in-situ measurement of sound reflection and airborne sound insulation characteristics of a noise barrier in Europe are currently performed following the CEN/TS 1793-5 European standard guidelines (last revision pu...The in-situ measurement of sound reflection and airborne sound insulation characteristics of a noise barrier in Europe are currently performed following the CEN/TS 1793-5 European standard guidelines (last revision published in 2003 [1]). After some years a large number of barriers measured, the original method has been significantly enhanced and validated in the frame of the EU funded QUIESST project, WP3 [2]. The sound reflection measurement method has been improved using a square 9-microphone grid not rigidly connected to the loudspeaker, an optimized alignment algorithm of free-field and reflected impulse responses, including fractional step shifts and least squares estimation of the best relative position, and a correction for geometrical divergence and sound source directivity. Each single measurement is then validated by means of the Reduction Factor calculation. The airborne sound insulation measurement method has not been markedly changed since 2003, because the procedure is robust and easily applicable as it is, but some problems may still be encountered when measuring highly insulating noise barriers, due to a poor signal to noise ratio of the transmitted impulse response. In those cases it is difficult to realize just after the measurement whether the obtained data are valid or not. A method, applicable on site, to overcome this problem is described here. It is based on the Signal to Noise Ratio estimation of critical parts of the acquired impulse responses and gives a strong validation criterion.展开更多
目的:研究强脉冲光联合A型肉毒毒素治疗玫瑰痤疮的疗效及对患者皮肤屏障功能、生活质量的影响。方法:收集2020年3月-2021年12月笔者医院收治的124例玫瑰痤疮患者以随机数字表法分组,对照1组(41例)接受A型肉毒毒素治疗,对照2组(42例)接...目的:研究强脉冲光联合A型肉毒毒素治疗玫瑰痤疮的疗效及对患者皮肤屏障功能、生活质量的影响。方法:收集2020年3月-2021年12月笔者医院收治的124例玫瑰痤疮患者以随机数字表法分组,对照1组(41例)接受A型肉毒毒素治疗,对照2组(42例)接受强脉冲光治疗,观察组(41例)接受强脉冲光联合A型肉毒毒素治疗。记录疗效、不良反应、1年复发情况、治疗前后症状积分、皮肤屏障功能、皮肤病生活质量指数问卷(Dermatology life quality index,DLQI)。结果:观察组的有效率高于对照1组、对照2组(P<0.05)。治疗后,观察组的症状积分、皮肤屏障功能(经皮水分丢失量、皮肤含水量、皮脂含量)及DLQI均优于对照1组和对照2组(P<0.05),对照1组与对照2组的症状积分、皮肤屏障功能、DLQI差异无统计学差异(P>0.05)。三组不良反应差异无统计学差异(P>0.05)。观察组的1年复发率低于对照1组、对照2组(P<0.05)。结论:强脉冲光联合A型肉毒毒素治疗玫瑰痤疮能够提高疗效,改善患者皮肤屏障功能和DLQI。展开更多
文摘The effects of minimally invasive surgery on the blood-brain barrier （BBB） of 30 patients with cerebral hemorrhage were investigated. Difference of the BBB index and serum MBP concentration were assessed in 15 cases of conservative treatment group and 15 cases of minimally invasive surgery group. The BBB index in minimally invasive surgery group was significantly lower than in conservative treatment group （P〈0.05）, and the BBB index in the two treatment groups was significantly higher than in control group （P〈0.01）. Serum MBP concentration in minimally invasive surgery group was significantly lower than in conservative treatment group （P〈0.05）, and that in the two treatment groups was significantly higher than in control group （P〈0.01）. It was suggested the permeability of BBB in patients with cerebral hemorrhage was increased, and BBB index and serum MBP concentration in patients with cerebral hemorrhage were increased. Minimally invasive surgery can reduce the lesion of cytotoxicity to BBB and cerebral edema.
文摘The in-situ measurement of sound reflection and airborne sound insulation characteristics of a noise barrier in Europe are currently performed following the CEN/TS 1793-5 European standard guidelines (last revision published in 2003 [1]). After some years a large number of barriers measured, the original method has been significantly enhanced and validated in the frame of the EU funded QUIESST project, WP3 [2]. The sound reflection measurement method has been improved using a square 9-microphone grid not rigidly connected to the loudspeaker, an optimized alignment algorithm of free-field and reflected impulse responses, including fractional step shifts and least squares estimation of the best relative position, and a correction for geometrical divergence and sound source directivity. Each single measurement is then validated by means of the Reduction Factor calculation. The airborne sound insulation measurement method has not been markedly changed since 2003, because the procedure is robust and easily applicable as it is, but some problems may still be encountered when measuring highly insulating noise barriers, due to a poor signal to noise ratio of the transmitted impulse response. In those cases it is difficult to realize just after the measurement whether the obtained data are valid or not. A method, applicable on site, to overcome this problem is described here. It is based on the Signal to Noise Ratio estimation of critical parts of the acquired impulse responses and gives a strong validation criterion.
文摘目的:研究强脉冲光联合A型肉毒毒素治疗玫瑰痤疮的疗效及对患者皮肤屏障功能、生活质量的影响。方法:收集2020年3月-2021年12月笔者医院收治的124例玫瑰痤疮患者以随机数字表法分组,对照1组(41例)接受A型肉毒毒素治疗,对照2组(42例)接受强脉冲光治疗,观察组(41例)接受强脉冲光联合A型肉毒毒素治疗。记录疗效、不良反应、1年复发情况、治疗前后症状积分、皮肤屏障功能、皮肤病生活质量指数问卷(Dermatology life quality index,DLQI)。结果:观察组的有效率高于对照1组、对照2组(P<0.05)。治疗后,观察组的症状积分、皮肤屏障功能(经皮水分丢失量、皮肤含水量、皮脂含量)及DLQI均优于对照1组和对照2组(P<0.05),对照1组与对照2组的症状积分、皮肤屏障功能、DLQI差异无统计学差异(P>0.05)。三组不良反应差异无统计学差异(P>0.05)。观察组的1年复发率低于对照1组、对照2组(P<0.05)。结论:强脉冲光联合A型肉毒毒素治疗玫瑰痤疮能够提高疗效,改善患者皮肤屏障功能和DLQI。
