Objective To observe influence of fibrin seala nt (FS)on osteoinductive ability of inject-type BMP.Method The inject-type BMP power was dissolved in the main glue p art or thrombin part of FS,then mixed with the main ...Objective To observe influence of fibrin seala nt (FS)on osteoinductive ability of inject-type BMP.Method The inject-type BMP power was dissolved in the main glue p art or thrombin part of FS,then mixed with the main glue part or thrombin pa rt of FS into gel,observe coagulating time,then implant comp osite into the thigh muscle pouch of m ice to evaluate their capacity to induce new bone formation,and compared to the single BMP implant gr oup.Result There was no difference in the coagul ating time between two mixing method,the osteoin-ductive ability of implants BMP dissolved in the main glue part or thrombin part of FS group was higher than that of simply BMP implant group.Conclusion FS was perfect carrier to inject-type BMP.展开更多
文摘Objective To observe influence of fibrin seala nt (FS)on osteoinductive ability of inject-type BMP.Method The inject-type BMP power was dissolved in the main glue p art or thrombin part of FS,then mixed with the main glue part or thrombin pa rt of FS into gel,observe coagulating time,then implant comp osite into the thigh muscle pouch of m ice to evaluate their capacity to induce new bone formation,and compared to the single BMP implant gr oup.Result There was no difference in the coagul ating time between two mixing method,the osteoin-ductive ability of implants BMP dissolved in the main glue part or thrombin part of FS group was higher than that of simply BMP implant group.Conclusion FS was perfect carrier to inject-type BMP.
