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一种改进Oriented RepPoints的遥感图像有向目标检测
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作者 谢国波 张家源 +1 位作者 林志毅 廖文康 《小型微型计算机系统》 CSCD 北大核心 2024年第11期2725-2731,共7页
为解决Oriented RepPoints算法在遥感图像有向目标检测中因遥感图像背景干扰信息较多和目标尺度大小不一所导致的检测精度不高、易漏检误检等问题,提出一种改进Oriented RepPoints的遥感图像有向目标检测方法MA-RPDet(Mixed Attention R... 为解决Oriented RepPoints算法在遥感图像有向目标检测中因遥感图像背景干扰信息较多和目标尺度大小不一所导致的检测精度不高、易漏检误检等问题,提出一种改进Oriented RepPoints的遥感图像有向目标检测方法MA-RPDet(Mixed Attention RepPoints Detector).首先,采用了PVTv2作为主干网络,该网络利用线性空间缩减自注意力机制提取出更具局部连续性的特征图,并保持与卷积运算类似的线性复杂度.其次,在特征融合阶段设计了串联性混合注意力模块,进一步强化了重要特征,促进了多尺度特征的高效交互.最后,引入平滑GIoU损失函数对模型学习策略进行优化,提高了检测精度.在两个遥感图像目标检测数据集DOTA和HRSC2016上的实验结果表明,所提方法的检测精度mAP分别达到了77.19%和90.3%,均高于其他对比算法,证明了本文方法的有效性. 展开更多
关键词 遥感图像 有向目标检测 oriented RepPoints 注意力机制 损失函数
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基于改进Oriented R-CNN的旋转框麦穗检测与计数模型 被引量:1
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作者 于俊伟 陈威威 +2 位作者 郭园森 母亚双 樊超 《农业工程学报》 EI CAS CSCD 北大核心 2024年第6期248-257,共10页
为对干扰、遮挡等复杂的田野环境中麦穗进行精准定位与计数,该研究提出了一种改进的Oriented R-CNN麦穗旋转框检测与计数方法,首先在主干网络中引入跨阶段局部空间金字塔(spatial pyramid pooling cross stage partial networks,SPPCSPC... 为对干扰、遮挡等复杂的田野环境中麦穗进行精准定位与计数,该研究提出了一种改进的Oriented R-CNN麦穗旋转框检测与计数方法,首先在主干网络中引入跨阶段局部空间金字塔(spatial pyramid pooling cross stage partial networks,SPPCSPC)模块扩大模型感受野,增强网络感知能力;其次,在颈网络中结合路径聚合网络(PANet,path aggregation network)和混合注意力机制(E2CBAM,efficient two convolutional block attention module),丰富特征图包含的特征信息;最后采用柔性非极大值抑制算法(Soft-NMS,soft-non maximum suppression)优化预测框筛选过程。试验结果显示,改进的模型对复杂环境中的麦穗检测效果良好。相较原模型,平均精确度均值mAP提高了2.02个百分点,与主流的旋转目标检测模型Gliding vertex、R3det、Rotated Faster R-CNN、S2anet和Rotated Retinanet相比,mAP分别提高了4.99、2.49、3.94、2.25和4.12个百分点。该研究方法利用旋转框准确定位麦穗位置,使得框内背景区域面积大幅度减少,为实际观察麦穗生长状况和统计数量提供了一种有效的方法。 展开更多
关键词 图像识别 作物 注意力机制 麦穗 oriented R-CNN
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Distributional and behavioral responses of the wintering Oriental Storks to drought in China’s largest freshwater lake
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作者 Fucheng Yang Mingqin Shao Jianying Wang 《Avian Research》 SCIE CSCD 2024年第2期187-195,共9页
Extreme droughts are increasing in frequency and severity globally as a result of climate change.Developing understanding of species’responses to drought is crucial for their conservation,especially in regions experi... Extreme droughts are increasing in frequency and severity globally as a result of climate change.Developing understanding of species’responses to drought is crucial for their conservation,especially in regions experi-encing increased aridity.Although numerous studies have investigated birds’responses to drought,the emphasis has primarily been on landbirds.Drought can significantly alter the wetland environments that waterbirds inhabit,but the response of waterbirds to drought remains understudied.In this study,we surveyed the distri-bution and behavior of Oriental Storks(Ciconia boyciana)in Poyang Lake,which is the largest freshwater lake in China.Results indicate that drought-induced catchment areas at the lowest water level limited the total popu-lation size of Oriental Storks in the sub-lakes.Sub-lakes with large catchment areas at the lowest water level demonstrated a capacity to support a larger population of wintering Oriental Storks.Over time,Oriental Storks exhibited a gradual concentration in Changhu Lake,characterized by larger catchments,after resource depletion in sub-lakes with smaller catchments.Additionally,the duration of Oriental Storks’vigilance and moving be-haviors decreased significantly compared with that observed before the drought.After the drought,Oriental Storks increased their foraging efforts,as evidenced by increased presence in deeper water and reaching their heads and necks into deeper water to forage,higher search rates,but lower foraging rates.In accordance with area-restricted search theory,reductions in habitat quality resulting from drought,including extensive fish die-offs,forced Oriental Storks to increase their foraging efforts.Sustaining a specific water area in sub-lakes during droughts can preserve resource availability,which is crucial for the conservation of Oriental Storks.Imple-menting measures such as water level control and micro-modification of lake bottoms in sub-lakes might mitigate the impact of drought on the piscivorous Oriental Storks. 展开更多
关键词 Climate change Extreme drought Foraging behavior oriental stork Poyang lake
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Three-dimensionally oriented organization of hexagonal MIL-96 microplates toward superior film microstructure
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作者 Sixing Chen Xinmiao Jin +3 位作者 Yuyang Wu Taotao Ji Fei Wang Yi Liu 《Chinese Journal of Chemical Engineering》 SCIE EI CAS CSCD 2024年第8期69-73,共5页
Preferential orientation control of metal—organic framework(MOF)films is advantageous for maximizing pore uniformity and minimizing grain-boundary defects.Nonetheless,the preparation of MOF films with both in-plane a... Preferential orientation control of metal—organic framework(MOF)films is advantageous for maximizing pore uniformity and minimizing grain-boundary defects.Nonetheless,the preparation of MOF films with both in-plane and out-of-plane orientations remains a grand challenge.In this study,we reported the preparation of three-dimensionally oriented MIL-96 layers through combining morphology control of MIL-96 seeds with addition of polyvinylpyrrolidone surfactants and arachidonic acids.The three-dimensionally oriented MIL-96 film was readily obtained through in-plane epitaxial growth.It is anticipated that the aforementioned protocol can be effective for obtaining diverse MOF films with a three-dimensionally oriented organization. 展开更多
关键词 Metaleorganic framework FILM orientation Epitaxial growth Morphological control
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Effects of orientation on the fatigue crack growth behaviors of the ZK60 magnesium alloy in air and PBS
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作者 Jiaqi Hu Zheng Liu +1 位作者 Zuoliang Ning Hong Gao 《Journal of Magnesium and Alloys》 SCIE EI CAS CSCD 2024年第1期281-294,共14页
Strong anisotropic corrosion and mechanical properties caused by specimen orientations greatly limit the applications of wrought magnesium alloys.To investigate the influences of specimen orientation,the corrosion tes... Strong anisotropic corrosion and mechanical properties caused by specimen orientations greatly limit the applications of wrought magnesium alloys.To investigate the influences of specimen orientation,the corrosion tests and(corrosion)fatigue crack growth tests were conducted.The rolled and transverse surfaces of the materials show distinct corrosion rate differences in the stable corrosion stage,but the truth is the opposite for the initial stage of corrosion.In air,specimen orientations have a significant influence on the plastic deformation mechanisms near the crack tip,which results in different fatigue fracture surfaces and cracking paths.Compared with R-T specimens,N-T specimens show a slower fatigue crack growth(FCG)rate in air,which can be attributed to crack closure effects and deformation twinning near the crack tip.The corrosion environment will not significantly change the main plastic deformation mechanisms for the same type of specimen.However,the FCG rate in phosphate buffer saline(PBS)is one order of magnitude higher than that in air,which is caused by the combined effects of hydrogen-induced cracking and anodic dissolution.Owing to the similar corrosion rates at crack tips,the specimens with different orientations display close FCG rates in PBS. 展开更多
关键词 Magnesium alloy orientATION CORROSION Fatigue crack growth
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Oriented Bounding Box Object Detection Model Based on Improved YOLOv8
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作者 ZHAO Xin-kang SI Zhan-jun 《印刷与数字媒体技术研究》 CAS 北大核心 2024年第4期67-75,114,共10页
In the study of oriented bounding boxes(OBB)object detection in high-resolution remote sensing images,the problem of missed and wrong detection of small targets occurs because the targets are too small and have differ... In the study of oriented bounding boxes(OBB)object detection in high-resolution remote sensing images,the problem of missed and wrong detection of small targets occurs because the targets are too small and have different orientations.Existing OBB object detection for remote sensing images,although making good progress,mainly focuses on directional modeling,while less consideration is given to the size of the object as well as the problem of missed detection.In this study,a method based on improved YOLOv8 was proposed for detecting oriented objects in remote sensing images,which can improve the detection precision of oriented objects in remote sensing images.Firstly,the ResCBAMG module was innovatively designed,which could better extract channel and spatial correlation information.Secondly,the innovative top-down feature fusion layer network structure was proposed in conjunction with the Efficient Channel Attention(ECA)attention module,which helped to capture inter-local cross-channel interaction information appropriately.Finally,we introduced an innovative ResCBAMG module between the different C2f modules and detection heads of the bottom-up feature fusion layer.This innovative structure helped the model to better focus on the target area.The precision and robustness of oriented target detection were also improved.Experimental results on the DOTA-v1.5 dataset showed that the detection Precision,mAP@0.5,and mAP@0.5:0.95 metrics of the improved model are better compared to the original model.This improvement is effective in detecting small targets and complex scenes. 展开更多
关键词 Remote sensing image oriented bounding boxes object detection Small target detection YOLOv8
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Estimation of cancer cell migration in biomimetic random/oriented collagen fiber microenvironments
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作者 姚静如 李国强 +8 位作者 姚喜耀 周连杰 叶志凯 刘艳平 郑栋天 唐婷 宋克纳 陈果 刘雳宇 《Chinese Physics B》 SCIE EI CAS CSCD 2024年第5期749-756,共8页
Increasing data indicate that cancer cell migration is regulated by extracellular matrixes and their surrounding biochemical microenvironment,playing a crucial role in pathological processes such as tumor invasion and... Increasing data indicate that cancer cell migration is regulated by extracellular matrixes and their surrounding biochemical microenvironment,playing a crucial role in pathological processes such as tumor invasion and metastasis.However,conventional two-dimensional cell culture and animal models have limitations in studying the influence of tumor microenvironment on cancer cell migration.Fortunately,the further development of microfluidic technology has provided solutions for the study of such questions.We utilize microfluidic chip to build a random collagen fiber microenvironment(RFM)model and an oriented collagen fiber microenvironment(OFM)model that resemble early stage and late stage breast cancer microenvironments,respectively.By combining cell culture,biochemical concentration gradient construction,and microscopic imaging techniques,we investigate the impact of different collagen fiber biochemical microenvironments on the migration of breast cancer MDA-MB-231-RFP cells.The results show that MDA-MB-231-RFP cells migrate further in the OFM model compared to the RFM model,with significant differences observed.Furthermore,we establish concentration gradients of the anticancer drug paclitaxel in both the RFM and OFM models and find that paclitaxel significantly inhibits the migration of MDA-MB-231-RFP cells in the RFM model,with stronger inhibition on the high concentration side compared to the low concentration side.However,the inhibitory effect of paclitaxel on the migration of MDA-MB-231-RFP cells in the OFM model is weak.These findings suggest that the oriented collagen fiber microenvironment resembling the late-stage tumor microenvironment is more favorable for cancer cell migration and that the effectiveness of anticancer drugs is diminished.The RFM and OFM models constructed in this study not only provide a platform for studying the mechanism of cancer development,but also serve as a tool for the initial measurement of drug screening. 展开更多
关键词 microfluidic chip random collagen fiber microenvironment(RFM) oriented collagen fiber microenvironment(OFM) cancer cell migration
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Analysis of the Effect of Problem-Oriented Nursing Intervention on Patients with Lower Extremity Arteriosclerosis Obliterans in Vascular Surgery
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作者 Yang An 《Journal of Clinical and Nursing Research》 2024年第4期1-6,共6页
Objective: To analyze the effect of problem-oriented nursing intervention on patients with lower extremity arteriosclerosis obliterans (ASO) in vascular surgery. Methods: The clinical data of 128 patients with lower e... Objective: To analyze the effect of problem-oriented nursing intervention on patients with lower extremity arteriosclerosis obliterans (ASO) in vascular surgery. Methods: The clinical data of 128 patients with lower extremity ASO in vascular surgery were selected and randomly divided into groups A and B, with 64 cases each. Group A is the control group, and Group B is the observation group. Group A received the routine nursing intervention, and Group B received the problem-oriented nursing intervention. The compliance, self-care ability, psychological state, quality of life, and nursing satisfaction of the two groups of patients were evaluated based on various indicators. Results: After the intervention, the evaluation of self-care ability (ESCA) score of the patients in Group B was higher than that of Group A, and the symptom checklist-90 (SCL-90) score was lower than that of Group A. The differences were significant (t = 10.019, t = 3.118, P < 0.01). After the intervention, the World Health Organization Quality of Life Brief (WHOQOL-BREF) index scores of the two groups increased and the increase in Group B was significantly higher than Group A (P < 0.001). The compliance rate of Group B (62/ 96.88%) was higher than that of Group A (52/ 81.25%), and the difference was extremely significant (χ2 = 8.020, P < 0.01). Conclusion: Problem-oriented nursing intervention for patients with lower extremity ASO in vascular surgery improved the patient’s self-care ability, and quality of life, reduced the patient’s negative emotions, and enhanced their overall satisfaction. 展开更多
关键词 Problem orientation Nursing intervention Vascular surgery Lower extremity arteriosclerosis obliterans
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Intervention Effect of Lower Limb Rehabilitation Robot with Task-Oriented Training on Stroke Patients and Its Influence on KFAROM Score
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作者 Maiding He Li Huang +9 位作者 Dekun Tang Mei Qin Ping Zhan Xichan Wang Xia Gao Jianzhu Wang Na Yin Hui Xu Yonghua Yang Kaihua Tang 《Journal of Biosciences and Medicines》 2024年第9期62-72,共11页
Objective: To explore the effect of lower limb rehabilitation robot combined with task-oriented training on stroke patients and its influence on KFAROM score. Methods: 100 stroke patients with hemiplegia admitted to o... Objective: To explore the effect of lower limb rehabilitation robot combined with task-oriented training on stroke patients and its influence on KFAROM score. Methods: 100 stroke patients with hemiplegia admitted to our hospital from January 2023 to December 2023 were randomly divided into two groups, the control group (50 cases) was given task-oriented training assisted by nurses, and the observation group (50 cases) was given lower limb rehabilitation robot with task-oriented training. Lower limb balance, lower limb muscle strength, motor function, ankle function, knee flexion range of motion and walking ability were observed. Results: After treatment, the scores of BBS, quadriceps femoris and hamstrings in the observation group were significantly higher than those in the control group (P Conclusion: In the clinical treatment of stroke patients, the combination of task-oriented training and lower limb rehabilitation robot can effectively improve the lower limb muscle strength, facilitate the recovery of balance function, and have a significant effect on the recovery of motor function, which can improve the walking ability of stroke patients and the range of motion of knee flexion, and achieve more ideal therapeutic effectiveness. 展开更多
关键词 Lower Limb Rehabilitation Robot Task-oriented Training STROKE KFAROM
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An Approach to Detect Structural Development Defects in Object-Oriented Programs
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作者 Maxime Seraphin Gnagne Mouhamadou Dosso +1 位作者 Mamadou Diarra Souleymane Oumtanaga 《Open Journal of Applied Sciences》 2024年第2期494-510,共17页
Structural development defects essentially refer to code structure that violates object-oriented design principles. They make program maintenance challenging and deteriorate software quality over time. Various detecti... Structural development defects essentially refer to code structure that violates object-oriented design principles. They make program maintenance challenging and deteriorate software quality over time. Various detection approaches, ranging from traditional heuristic algorithms to machine learning methods, are used to identify these defects. Ensemble learning methods have strengthened the detection of these defects. However, existing approaches do not simultaneously exploit the capabilities of extracting relevant features from pre-trained models and the performance of neural networks for the classification task. Therefore, our goal has been to design a model that combines a pre-trained model to extract relevant features from code excerpts through transfer learning and a bagging method with a base estimator, a dense neural network, for defect classification. To achieve this, we composed multiple samples of the same size with replacements from the imbalanced dataset MLCQ1. For all the samples, we used the CodeT5-small variant to extract features and trained a bagging method with the neural network Roberta Classification Head to classify defects based on these features. We then compared this model to RandomForest, one of the ensemble methods that yields good results. Our experiments showed that the number of base estimators to use for bagging depends on the defect to be detected. Next, we observed that it was not necessary to use a data balancing technique with our model when the imbalance rate was 23%. Finally, for blob detection, RandomForest had a median MCC value of 0.36 compared to 0.12 for our method. However, our method was predominant in Long Method detection with a median MCC value of 0.53 compared to 0.42 for RandomForest. These results suggest that the performance of ensemble methods in detecting structural development defects is dependent on specific defects. 展开更多
关键词 Object-oriented Programming Structural Development Defect Detection Software Maintenance Pre-Trained Models Features Extraction BAGGING Neural Network
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Construction of Oriented Structure in Inner Surface of Small-Diameter Artificial Blood Vessels:A Review 被引量:1
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作者 伊光辉 成馨雨 +3 位作者 耿梦想 孟凯 张克勤 赵荟菁 《Journal of Donghua University(English Edition)》 CAS 2023年第2期149-163,共15页
There is an urgent need for small-diameter artificial blood vessels in clinic.Physical,chemical and biological factors should be integrated to avoid thrombosis and intimal hyperplasia after implantation and to promote... There is an urgent need for small-diameter artificial blood vessels in clinic.Physical,chemical and biological factors should be integrated to avoid thrombosis and intimal hyperplasia after implantation and to promote successful fabrication of small-diameter artificial blood vessels.From a physical perspective,the internal oriented structures of natural blood vessels plays an important role in guiding the directional growth of cells,improving the blood flow environment,and promoting the regeneration of vascular tissue.In this review,the effects of the oriented structures on cells,including endothelial cells(ECs),smooth muscle cells(SMCs)and stem cells,as well as the effect of the oriented structures on hemodynamics and vascular tissue remodeling and regeneration are introduced.Various forms of oriented structures(fibers,grooves,channels,etc.)and their construction methods are also reviewed.Conclusions and future perspectives are given.It is expected to give some references to relevant researches. 展开更多
关键词 small-diameter artificial blood vessel internal oriented structure direct cell behavior vascular tissue remodeling and regeneration
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Constructing an ion‐oriented channel on a zinc electrode through surface engineering 被引量:2
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作者 Xin Liu Kun Wang +6 位作者 Ying Liu Fuhua Zhao Jianjiang He Hao Wu Jianfei Wu Han‐Pu Liang Changshui Huang 《Carbon Energy》 SCIE EI CAS CSCD 2023年第11期2-14,共13页
The inherent shortcomings of a zinc anode in aqueous zinc‐ion batteries(ZIBs)such as zinc dendrites and side reactions severely limit their practical application.Herein,to address these issues,an ion‐oriented transp... The inherent shortcomings of a zinc anode in aqueous zinc‐ion batteries(ZIBs)such as zinc dendrites and side reactions severely limit their practical application.Herein,to address these issues,an ion‐oriented transport channel constructed by graphdiyne(GDY)nanowalls is designed and grown in situ on the surface of a zinc electrode.The vertically stacked GDY nanowalls with a unique hierarchical porous structure and mechanical properties form a nanomesh‐like interface on the zinc electrode,acting as an ion‐oriented channel,which can efficiently confine the segmented growth of zinc metal in microscopic regions of hundreds of nanometers.In those microscopic regions,the uniform domain current density is effortlessly maintained compared with a large surface area,thereby inhibiting zinc dendrites effectively.Besides,due to the presence of the ion‐oriented channel,the modified zinc anode demonstrates long‐term stable zinc plating/stripping performance for more than 600 h at 1 mAh cm^(−2)in an aqueous electrolyte.In addition,full‐cells coupled with MnO2 show high specific capacity and power density,as well as excellent cycling stability with a capacity retention of 82%after 5000 cycles at 1 A g^(−1).This work provides a feasible and accessible surface engineering approach to modify the electrode interface for confined and dendrite‐free zinc deposition in aqueous ZIBs. 展开更多
关键词 DENDRITE graphdiyne ion‐oriented channel nanomesh interface zinc‐ion batteries
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厄瓜多尔Oriente盆地白垩系Napo组LU亚段沉积模式
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作者 韩立杨 孙雨 +3 位作者 张克鑫 闫百泉 张超前 杨国庆 《海洋地质前沿》 CSCD 北大核心 2024年第5期80-90,共11页
厄瓜多尔Oriente盆地北部白垩系Napo组LU亚段地层油气资源极其丰富,具有较大的油气勘探潜力,由于目前对LU亚段地层沉积模式认识不清晰,极大程度上限制了研究区进一步勘探开发。依据LU亚段岩芯观察、测井、成熟度分析以及镜下薄片等资料... 厄瓜多尔Oriente盆地北部白垩系Napo组LU亚段地层油气资源极其丰富,具有较大的油气勘探潜力,由于目前对LU亚段地层沉积模式认识不清晰,极大程度上限制了研究区进一步勘探开发。依据LU亚段岩芯观察、测井、成熟度分析以及镜下薄片等资料,通过岩芯岩性、结构等岩石学特征,沉积构造、生物遗迹化石、沉积韵律等沉积学特征,以及测井相标志认为,研究区LU亚段地层发育于潮汐作用为主的海陆过渡环境,并在前人研究基础上提出潮控河口湾与陆棚之间存在过渡带沉积,形成了潮控河口湾-过渡带-陆棚沉积体系,识别出潮汐水道、潮汐砂坝、砂坪、海绿石砂席、混合坪、陆棚泥和灰质滩共7种沉积微相,其中,优势储层相带为潮汐水道和潮汐砂坝,砂坪次之。建立研究区潮控河口湾-过渡带-陆棚沉积模式,以期对Oriente盆地白垩系Napo组油气勘探提供有利的科学依据。 展开更多
关键词 沉积模式 沉积微相 潮控河口湾 oriente盆地
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Influence of heat treatment on microstructure,mechanical and corrosion behavior of WE43 alloy fabricated by laser-beam powder bed fusion 被引量:5
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作者 Chenrong Ling Qiang Li +6 位作者 Zhe Zhang Youwen Yang Wenhao Zhou Wenlong Chen Zhi Dong Chunrong Pan Cijun Shuai 《International Journal of Extreme Manufacturing》 SCIE EI CAS CSCD 2024年第1期258-275,共18页
Magnesium(Mg)alloys are considered to be a new generation of revolutionary medical metals.Laser-beam powder bed fusion(PBF-LB)is suitable for fabricating metal implants withpersonalized and complicated structures.Howe... Magnesium(Mg)alloys are considered to be a new generation of revolutionary medical metals.Laser-beam powder bed fusion(PBF-LB)is suitable for fabricating metal implants withpersonalized and complicated structures.However,the as-built part usually exhibits undesirable microstructure and unsatisfactory performance.In this work,WE43 parts were firstly fabricated by PBF-LB and then subjected to heat treatment.Although a high densification rate of 99.91%was achieved using suitable processes,the as-built parts exhibited anisotropic and layeredmicrostructure with heterogeneously precipitated Nd-rich intermetallic.After heat treatment,fine and nano-scaled Mg24Y5particles were precipitated.Meanwhile,theα-Mg grainsunderwent recrystallization and turned coarsened slightly,which effectively weakened thetexture intensity and reduced the anisotropy.As a consequence,the yield strength and ultimate tensile strength were significantly improved to(250.2±3.5)MPa and(312±3.7)MPa,respectively,while the elongation was still maintained at a high level of 15.2%.Furthermore,the homogenized microstructure reduced the tendency of localized corrosion and favoredthe development of uniform passivation film.Thus,the degradation rate of WE43 parts was decreased by an order of magnitude.Besides,in-vitro cell experiments proved their favorable biocompatibility. 展开更多
关键词 laser-beam powder bed fusion WE43 alloys heat treatment mechanical performance biodegradation behavior
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Integrated ribosome and proteome analyses reveal insights into sevoflurane-induced long-term social behavior and cognitive dysfunctions through ADNP inhibition in neonatal mice 被引量:1
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作者 Li-Rong Liang Bing Liu +9 位作者 Shu-Hui Cao You-Yi Zhao Tian Zeng Mei-Ting Zhai Ze Fan Dan-Yi He San-Xin Ma Xiao-Tong Shi Yao Zhang Hui Zhang 《Zoological Research》 SCIE CSCD 2024年第3期663-678,共16页
A growing number of studies have demonstrated that repeated exposure to sevoflurane during development results in persistent social abnormalities and cognitive impairment.Davunetide,an active fragment of the activity-... A growing number of studies have demonstrated that repeated exposure to sevoflurane during development results in persistent social abnormalities and cognitive impairment.Davunetide,an active fragment of the activity-dependent neuroprotective protein(ADNP),has been implicated in social and cognitive protection.However,the potential of davunetide to attenuate social deficits following sevoflurane exposure and the underlying developmental mechanisms remain poorly understood.In this study,ribosome and proteome profiles were analyzed to investigate the molecular basis of sevoflurane-induced social deficits in neonatal mice.The neuropathological basis was also explored using Golgi staining,morphological analysis,western blotting,electrophysiological analysis,and behavioral analysis.Results indicated that ADNP was significantly down-regulated following developmental exposure to sevoflurane.In adulthood,anterior cingulate cortex(ACC)neurons exposed to sevoflurane exhibited a decrease in dendrite number,total dendrite length,and spine density.Furthermore,the expression levels of Homer,PSD95,synaptophysin,and vglut2 were significantly reduced in the sevoflurane group.Patch-clamp recordings indicated reductions in both the frequency and amplitude of miniature excitatory postsynaptic currents(mEPSCs).Notably,davunetide significantly ameliorated the synaptic defects,social behavior deficits,and cognitive impairments induced by sevoflurane.Mechanistic analysis revealed that loss of ADNP led to dysregulation of Ca^(2+)activity via the Wnt/β-catenin signaling,resulting in decreased expression of synaptic proteins.Suppression of Wnt signaling was restored in the davunetide-treated group.Thus,ADNP was identified as a promising therapeutic target for the prevention and treatment of neurodevelopmental toxicity caused by general anesthetics.This study provides important insights into the mechanisms underlying social and cognitive disturbances caused by sevoflurane exposure in neonatal mice and elucidates the regulatory pathways involved. 展开更多
关键词 Davunetide SEVOFLURANE Abnormal social behaviors ADNP NEUROTOXICITY
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The Influence of Crystallographic Orientation and Grain Boundary on Nanoindentation Behavior of Inconel 718 Superalloy Based on Crystal Plasticity Theory
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作者 Wenbo Zhu Guangjian Yuan +2 位作者 Jianping Tan Shuai Chang Shantung Tu 《Chinese Journal of Mechanical Engineering》 SCIE EI CAS CSCD 2023年第4期385-396,共12页
The crystal plasticity finite element method(CPFEM)is widely used to explore the microscopic mechanical behavior of materials and understand the deformation mechanism at the grain-level.However,few CPFEM simulation st... The crystal plasticity finite element method(CPFEM)is widely used to explore the microscopic mechanical behavior of materials and understand the deformation mechanism at the grain-level.However,few CPFEM simulation studies have been carried out to analyze the nanoindentation deformation mechanism of polycrystalline materials at the microscale level.In this study,a three-dimensional CPFEM-based nanoindentation simulation is performed on an Inconel 718 polycrystalline material to examine the influence of different crystallographic parameters on nanoindentation behavior.A representative volume element model is developed to calibrate the crystal plastic constitutive parameters by comparing the stress-strain data with the experimental results.The indentation force-displacement curves,stress distributions,and pile-up patterns are obtained by CPFEM simulation.The results show that the crystallographic orientation and grain boundary have little influence on the force-displacement curves of the nanoindentation,but significantly influence the local stress distributions and shape of the pile-up patterns.As the difference in crystallographic orientation between grains increases,changes in the pile-up patterns and stress distributions caused by this effect become more significant.In addition,the simulation results reveal that the existence of grain boundaries affects the continuity of the stress distribution.The obstruction on the continuity of stress distribution increases as the grain boundary angle increases.This research demonstrates that the proposed CPFEM model can well describe the microscopic compressive deformation behaviors of Inconel 718 under nanoindentation. 展开更多
关键词 Crystal plasticity Grain boundary Crystallographic orientation NANOINDENTATION
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Exploring heteroepitaxial growth and electrical properties of α-Ga_(2)O_(3) films on differently oriented sapphire substrates
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作者 Wei Wang Shudong Hu +7 位作者 Zilong Wang Kaisen Liu Jinfu Zhang Simiao Wu Yuxia Yang Ning Xia Wenrui Zhang Jichun Ye 《Journal of Semiconductors》 EI CAS CSCD 2023年第6期46-51,共6页
This study explores the epitaxial relationship and electrical properties of α-Ga_(2)O_(3) thin films deposited on a-plane, mplane, and r-plane sapphire substrates. We characterize the thin films by X-ray diffraction ... This study explores the epitaxial relationship and electrical properties of α-Ga_(2)O_(3) thin films deposited on a-plane, mplane, and r-plane sapphire substrates. We characterize the thin films by X-ray diffraction and Raman spectroscopy, and elucidate thin film epitaxial relationships with the underlying sapphire substrates. The oxygen vacancy concentration of α-Ga_(2)O_(3) thin films on m-plane and r-plane sapphire substrates are higher than α-Ga_(2)O_(3) thin film on a-plane sapphire substrates. All three thin films have a high transmission of over 80% in the visible and near-ultraviolet regions, and their optical bandgaps stay around 5.02–5.16 eV. Hall measurements show that the α-Ga_(2)O_(3) thin film grown on r-plane sapphire has the highest conductivity of 2.71 S/cm, which is at least 90 times higher than the film on a-plane sapphire. A similar orientation-dependence is seen in their activation energy as revealed by temperature-dependent conductivity measurements, with 0.266, 0.079, and 0.075eV for the film on a-, m-, r-plane, respectively. The origin of the distinct transport behavior of films on differently oriented substrates is suggested to relate with the distinct evolution of oxygen vacancies at differently oriented substrates. This study provides insights for the substrate selection when growing α-Ga_(2)O_(3) films with tunable transport properties. 展开更多
关键词 gallium oxide thin film epitaxy orientATION oxygen vacancy electrical properties
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Association of preschool children behavior and emotional problems with the parenting behavior of both parents 被引量:1
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作者 Su-Mei Wang Shuang-Qin Yan +4 位作者 Fang-Fang Xie Zhi-Ling Cai Guo-Peng Gao Ting-Ting Weng Fang-Biao Tao 《World Journal of Clinical Cases》 SCIE 2024年第6期1084-1093,共10页
BACKGROUND Parental behaviors are key in shaping children’s psychological and behavioral development,crucial for early identification and prevention of mental health issues,reducing psychological trauma in childhood.... BACKGROUND Parental behaviors are key in shaping children’s psychological and behavioral development,crucial for early identification and prevention of mental health issues,reducing psychological trauma in childhood.AIM To investigate the relationship between parenting behaviors and behavioral and emotional issues in preschool children.METHODS From October 2017 to May 2018,7 kindergartens in Ma’anshan City were selected to conduct a parent self-filled questionnaire-Health Development Survey of Preschool Children.Children’s Strength and Difficulties Questionnaire(Parent Version)was applied to measures the children’s behavioral and emotional performance.Parenting behavior was evaluated using the Parental Behavior Inventory.Binomial logistic regression model was used to analyze the association between the detection rate of preschool children’s behavior and emotional problems and their parenting behaviors.RESULTS High level of parental support/participation was negatively correlated with conduct problems,abnormal hyperactivity,abnormal total difficulty scores and abnormal prosocial behavior problems.High level of maternal support/participation was negatively correlated with abnormal emotional symptoms and abnormal peer interaction in children.High level of parental hostility/coercion was positively correlated with abnormal emotional symptoms,abnormal conduct problems,abnormal hyperactivity,abnormal peer interaction,and abnormal total difficulty scores in children(all P<0.05).Moreover,paternal parenting behaviors had similarly effects on behavior and emotional problems of preschool children compared with maternal parenting behaviors(all P>0.05),after calculating ratio of odds ratio values.CONCLUSION Our study found that parenting behaviors are associated with behavioral and emotional issues in preschool children.Overall,the more supportive or involved the parents are,the fewer behavioral and emotional problems the children experience;conversely,the more hostile or controlling the parents are,the more behavioral and emotional problems the children face.Moreover,the impact of fathers’parenting behaviors on preschool children’s behavior and emotions is no less significant than that of mothers’parenting behaviors. 展开更多
关键词 CHILDREN Preschool age PARENTING behaviorAL Parenting problems
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Shear behavior of single-joint bolted sandstone subjected to dryewet cycles:Experimental and analytical approaches 被引量:1
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作者 Luobin Zheng Kaiwen Liu 《Journal of Rock Mechanics and Geotechnical Engineering》 SCIE CSCD 2024年第10期4216-4228,共13页
A series of direct shear tests under constant normal loading conditions were carried out on specimens of bolted sandstone single-joint treated with different numbers of dryewet cycles.The experimental results show tha... A series of direct shear tests under constant normal loading conditions were carried out on specimens of bolted sandstone single-joint treated with different numbers of dryewet cycles.The experimental results show that the peak shear strength and shear stiffness of bolted sandstone joints were significantly reduced after 12 dryewet cycles.The decrease in the shear strength of rough joints is more significant than that of flat joints.Due to the decrease in the strength of the surrounding rock,the deformation characteristics of the bolts are significantly affected by the number of dryewet cycles performed.With an increase in the number of dryewet cycles,the plastic hinge length of the bolt gradually increases,resulting in an increase in the corresponding shear displacement when the bolt breaks.Compared with the tensileeshear failure mode of the bolts in flat joints,the tensileebending failure mode arises for bolts in rough joints.A shear curve model describing the whole process of bolted rock joints is established based on the deterioration of rock mechanical parameters caused by dry‒wet cycles.The model proposed considers the change in the friction angle of the joint surface with the shear displacement,which is applied to the derivation of the model by introducing the dynamic evolutionary friction angle parameter.The reasonably good agreement between a predicted curve and the corresponding experimental curve indicates that this method can effectively predict the shear strength of a bolted rock joint involving rough joint under dryewet cycling conditions. 展开更多
关键词 Reinforcement technique Interface behavior Bolted sandstone Cyclic dryingewetting Analytical model
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Microstructures and micromechanical behaviors of high -entropy alloys investigated by synchrotron X-ray and neutron diffraction techniques: A review 被引量:1
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作者 Yubo Huang Ning Xu +3 位作者 Huaile Lu Yang Ren Shilei Li Yandong Wang 《International Journal of Minerals,Metallurgy and Materials》 SCIE EI CAS CSCD 2024年第6期1333-1349,共17页
High-entropy alloys(HEAs)possess outstanding features such as corrosion resistance,irradiation resistance,and good mechan-ical properties.A few HEAs have found applications in the fields of aerospace and defense.Exten... High-entropy alloys(HEAs)possess outstanding features such as corrosion resistance,irradiation resistance,and good mechan-ical properties.A few HEAs have found applications in the fields of aerospace and defense.Extensive studies on the deformation mech-anisms of HEAs can guide microstructure control and toughness design,which is vital for understanding and studying state-of-the-art structural materials.Synchrotron X-ray and neutron diffraction are necessary techniques for materials science research,especially for in situ coupling of physical/chemical fields and for resolving macro/microcrystallographic information on materials.Recently,several re-searchers have applied synchrotron X-ray and neutron diffraction methods to study the deformation mechanisms,phase transformations,stress behaviors,and in situ processes of HEAs,such as variable-temperature,high-pressure,and hydrogenation processes.In this review,the principles and development of synchrotron X-ray and neutron diffraction are presented,and their applications in the deformation mechanisms of HEAs are discussed.The factors that influence the deformation mechanisms of HEAs are also outlined.This review fo-cuses on the microstructures and micromechanical behaviors during tension/compression or creep/fatigue deformation and the application of synchrotron X-ray and neutron diffraction methods to the characterization of dislocations,stacking faults,twins,phases,and intergrain/interphase stress changes.Perspectives on future developments of synchrotron X-ray and neutron diffraction and on research directions on the deformation mechanisms of novel metals are discussed. 展开更多
关键词 high-entropy alloys MICROSTRUCTURES micromechanical behaviors synchrotron X-ray diffraction neutron diffraction
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