The spectroscopic properties of benzophenoxazin 5 one derivatives (3a-3m) including newly synthesized 3k-3m from 4 nitrosoaniline hydrochlorides and ethyl 1,3 dihydroxy 2 na^ph^thoate were studied. Compound ...The spectroscopic properties of benzophenoxazin 5 one derivatives (3a-3m) including newly synthesized 3k-3m from 4 nitrosoaniline hydrochlorides and ethyl 1,3 dihydroxy 2 na^ph^thoate were studied. Compound 3l was converted into a covalent product with DNA, which had a blue shift of the fluorescence maximum. Compounds 3a-3k were found to undergo interaction with DNA and their complexes with DNA had a red shift of the fluorescence maximum and showed increasing melting temperature of DNA. Compound 3m DNA had a blue shift of the fluorescence maximum to 3m and showed decreasing melting temperature of DNA.展开更多
文摘The spectroscopic properties of benzophenoxazin 5 one derivatives (3a-3m) including newly synthesized 3k-3m from 4 nitrosoaniline hydrochlorides and ethyl 1,3 dihydroxy 2 na^ph^thoate were studied. Compound 3l was converted into a covalent product with DNA, which had a blue shift of the fluorescence maximum. Compounds 3a-3k were found to undergo interaction with DNA and their complexes with DNA had a red shift of the fluorescence maximum and showed increasing melting temperature of DNA. Compound 3m DNA had a blue shift of the fluorescence maximum to 3m and showed decreasing melting temperature of DNA.
