Synthesis, Characterization and Properties of Polymeric p-Benzoyl-4,4'-Diaminobenzoylaniline

An aromatic polyamide was synthesized by low-temperature poly-condensation reaction from terephthaloyl chloride and 4,4'-diaminobenzanilide (4,4'-DABA). The synthesized polyamide had a characteristic peak of carbon atoms in the amide group at 166 ppm, which was demonstrated by the solid nuclear magnetic resonance carbon spectrum. It was shown to be the stretching vibration absorption peak of the amide N-H bond at 3342 cm−1 by Fourier infrared (FT-IR) spectroscopy. It was obtained that the energy band near 1100 - 1276 cm−1 belongs to the absorption peak of the para-substituted benzene ring and the band near 2977 cm−1 was the C-H stretching vibration peak of the benzene ring by Raman spectroscopy. The molecular structure of the synthesized polyamide compound was confirmed by FT-IR, Raman, and solid 13C-NMR spectroscopies. It was proved that the polymer is stable up to 300˚C and has a relatively high stability by the thermogravimetric analysis. It was also confirmed by the fluorescence spectrum that it has a strong blue fluorescence near 420 nm. The morphological characteristics of the polymer were further demonstrated by electron scanning electron microscopy (SEM). The properties of polymeric p-benzoyl-4,4'-diaminobenzoyl-aniline were found to emit strong blue fluorescence and have good thermal stability, making it a promising functional material for fluorescence in the blue region with potential for large-scale applications.

Synthesis, Characterization and Properties of Polymeric p-Benzoyl-4,4'-Diaminobenzoylaniline

An aromatic polyamide was synthesized by low-temperature poly-condensation reaction from terephthaloyl chloride and 4,4'-diaminobenzanilide (4,4'-DABA). The synthesized polyamide had a characteristic peak of carbon atoms in the amide group at 166 ppm, which was demonstrated by the solid nuclear magnetic resonance carbon spectrum. It was shown to be the stretching vibration absorption peak of the amide N-H bond at 3342 cm−1 by Fourier infrared (FT-IR) spectroscopy. It was obtained that the energy band near 1100 - 1276 cm−1 belongs to the absorption peak of the para-substituted benzene ring and the band near 2977 cm−1 was the C-H stretching vibration peak of the benzene ring by Raman spectroscopy. The molecular structure of the synthesized polyamide compound was confirmed by FT-IR, Raman, and solid 13C-NMR spectroscopies. It was proved that the polymer is stable up to 300˚C and has a relatively high stability by the thermogravimetric analysis. It was also confirmed by the fluorescence spectrum that it has a strong blue fluorescence near 420 nm. The morphological characteristics of the polymer were further demonstrated by electron scanning electron microscopy (SEM). The properties of polymeric p-benzoyl-4,4'-diaminobenzoyl-aniline were found to emit strong blue fluorescence and have good thermal stability, making it a promising functional material for fluorescence in the blue region with potential for large-scale applications.

The Benzoylation of 6-Methyluracil and 5-Nitro-6-methyluracil

Methyluracil and 5-nitro-6-methyluracil react with variable molar quantities of benzoyl chloride in acetonitrile-pyridine at room temperature to give 1-N, 3-N-dibenzoyl-6- methyluracil 3b and 1-N-benzoyl-5-nitro-6-methyluracil 4b. The reactive rates of debenzoylation of 3b and 4b were investigated.

Synthesis and Crystal Structure of Lanthanum Nitrate with Methyl-2-pyridyl Ketone Benzoyl Hydrazone

A novel La complex with methyl-2-pyridyl ketone benzoyl hydrazone has been synthesized and determined by single crystal X-ray diffraction. The crystal is monoclinic with space group C2/c, a =1 7081(3) nm, b =1 5660(3) nm, c =1 3512(3) nm, α=90 00°, β=94 39(1)°, γ=90 00°, V =3 6037(12) nm 3, Z =4 . The complex is a ten-coordinated one with a lanthanum ion surrounded by a N 4O 6 set. The crystal structure is stabilized by hydrogen bonds between water molecules and NO - 3 anions.

Theoretical Studies on Thermal Decomposition of Benzoyl Peroxide in Ground State

Systematic studies of the thermal decomposition mechanism of benzoyl peroxide(BPO) in ground state, leading to various intermediates, products and the potential energy surface(PES) of possible dissociation reactions were made computationally. The structures of the transition states and the activation energies for all the paths causing the formation of the reaction products mentioned above were calculated by the AM1 semi-empirical method. This method is shown to to be one predict correctly the preferred pathway for the title reaction. It has been found that in ground state, the thermal decomposition of benzoyl peroxide has two kinds of paths. The first pathway PhC(O)O-OC(O)Ph→PhC(O)O · →Ph · +CO 2 produces finally phenyl radicals and carbon dioxide. And the second pathway PhC(O)OO-C(O)Ph→PhC(O)OO · +PhC(O) · → PhC(O) · +O 2 →Ph · +CO+O 2, via which the reaction takes place only in two steps, produces oxygen and PhC(O) · radicals, and the further thermal dissociation of PhC(O) · is quite difficult because of the high activation energy in ground state. The calculated activation energies and reaction enthalpies are in good agreement with the experimental values. The research results also show that also the thermal dissociation process of the two bonds or the three bonds for the benzoyl peroxide doesn′t take place in ground state.

THE REACTION OF BENZOYL SUBSTITUTED HETEROCYCLIC KETENE AMINALS WITH ARYL AZIDES.A FACILE APPROACH TO SYNTHSIZE 1,5-DIARYL-4-(2-IMIDAZOLINYL)-1,2,3-TRIAZOLES

Heterocyclic ketene aminals 1 react with aryl azides 2 to give the titled compounds 3,and in some cases also with the formation of fused heterocycles 4.

An Improved High Performance Liquid Chromatographic Method for Identification and Quantization of Polyamines as Benzoylated Derivatives

A simple reversed phase HPLC method was developed for the determination of Putrescine, Cadaverine and Spermidine (a class of polyamines) in their benzoylated form from external known standards. In the optimization procedure, a number of parameters were examined: 1) Solvent used in the extraction of standard polyamines (diethyl ether versus chloroform);2) Solvent used in the elution of the polyamine (methanol versus acetonitrile);3) Mode of derivatization and extraction step(s) (derivatization and extraction performed together versus derivatization and extraction performed separately);and 4) Other instrumental parameters (such as UV detection wavelength, gradient profiles). The advantages of our method, relative to the standard Morgan method are: a) decreased chromatographic runtime, b) ease of preparation with good resolution, sensitivity, and reproducibility using a standard RP-HPLC method.

Extraction Behavior of Rare Earths with 1-phenyl-3-methyl-4-benzoyl-pyrazolone-5 Using Solid-liquid Extraction Technique

The extraction behavior of rare earths was studied by using paraffin with ceresin as a diluent containing 1-phenyl-3-methyl-4-benzoyl-pyrazolone-5.In solid phase,the composition of complexes is REP_3.The equilib- rium extraction constants and pH_(1/2) values of solid-liquid extraction are higher than those of normal liquid-liquid extraction.The extraction efficiency tends to maximum when the ratio of phases is 1:1.When the extraction temperature is higher than the melting point of paraffin and the extraction time is over 10 min,the extraction efficiency keeps constant.Moreover,the relationship among separation factor,equilibrium extrac- tion constant,pH_(1/2) value and atomic number was obtained.The mechanism of solid-liquid extraction is analogous to that of liquid-liquid extraction.

In situ Preparation of Tri-Fe(Ⅲ) and Bi-Cu(Ⅱ) Clusters from Benzoyl Peroxide Reacting with Metal Powders

Three crystal architectures, including one organic compound of benzoyl peroxide（Ⅰ） and two clusters of tri-iron（Ⅲ） and bi-cupper（Ⅱ） with benzoic ligands（2 and 3）, were self-assembled by an in situ redox way of benzoyl peroxide oxidants reacting with Mo, Fe and Cu powders, respectively. X-ray crystallographic results show that both the asymmetry tri-iron（Ⅲ） cluster and the benzoylperoxide crystal architecture（2 and 1） with complicated 3D networks were constructed by intermolecular hydrogen-bonding interactions. Contrarily, the symmetrical bi-copper（Ⅱ） cluster crystal architecture（3）, only with π-π stacking between paralleled phenyl groups and without any intermolecular hydrogen-bonding interactions, only presented an 1D zigzag chain along the a-axis.

Benzoylation of Toluene over Alpromoted SO^(2-)_(4)/MxOy(M=Zr, Ti, Fe) Catalysts

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Synthesis and Biological Evaluation of Substituted 3＇－N－Benzoyl Taxol Analogs

A series of subshtuted 3'-N-benzoyl taxol analogs [7a￣i] were synthesized by Schotten-Baumann acylation of the key intermediate, 13-O-[(2'R, 3' S) -3'-phenylisoserinoyl]baccatin Ⅲ[6]. Evaluation of the newly ￣ derivatives for cytotoxicity against KB Cell line revealed that electrondon-donating groups at the para position (such as -CH3, -OCH3, etc.) havepositive effect on achvity, while electron-attracting groups(such as -NO2, -Br, etc.) have negativeeffect. Sterically hindered substituents at the ortho position could dramatically reduce the activity.But none of the analogs had higher cytotoxicity than taxol.

Dimerization Constant Determination of 6－O－Benzoyl－β－Cyclodextrin in Aqueous Solution．

Dimerization Constant of 6-O-benzoyl-β-CD,which is insoluble in water,was determined for the first time by a calculation method involving an approximation step as well as a geometric step.This calculation method can be applied to other functionally modified cyclodextrin host compounds.

An Investigation on Polypropylene Degradation in Supercritical Water Adding Benzoyl Peroxide

The effect of benzoyl peroxide （BPO） on polypropylene （PP） degradation in supercritical water was investigated with the aim of developing a process for recycling of waste plastics. A series of experiments with and without BPO were carried out at temperatures of 653 K and 673 K under pressure about 26 MPa for 30, 75 and 120 min respectively. Products were analyzed by an Ostward-type viscometer, gas chromatography and spectrometry （GC/MS） etc. The results indicated that mean molecular weight of the samples decreased greatly along with the time elapsing or with the temperature increasing, and PP was decomposed to Miphatic and cycloparaftinic hydrocarbons but a few benzenoid hydrocarbons. By comparing the experiments with and without BPO, it was made clear that BPO is an effective additive on PP degradation in supercritical water.

Rate Enhancements in the Acetylation and Benzoylation of Certain Aromatic Compounds with Vilsmeier-Haack Reagents Using Acetamide, Benzamide and Oxychlorides under Non-Conventional Conditions

Acetylation and benzoylation reactions of certain aromatic aldehydes, ketones with Vilsmeier-Haack Re- agents using Acetamide and Oxychloride (SOCl2 or POCl3) under conventional (thermal) and non conven- tional [microwave irradiated (MIR), ultrasonic assisted and solvent free mortar pestle (grinding)] conditions. Reactions afforded good to excellent yields of products with both the VH reagents, reaction times were fairly less in the case of [amide/POCl3] than those of [amide/SOCl2] reagent. Reactions are dramatically acceler- ated in under sonicated and microwave irradiations with a trend: MIR (few seconds) >> Sonication (minutes) > Grinding (min) >> thermal (several hrs).

Chiral Separation of N-Benzoyl Phenylalanine Methyl Ester by Nonaqueous Capillary Electrophoresis

A successful chiral separation of N-benzoyl phenylalanine methyl ester has been achieved by nonaqueous capillary electrophoresis (NACE) using P-CD as chiral selector in formamide (FA). Some experimental parameters influencing the chiral separation such as concentration of P-CD, ionic strength and apparent pH (pH*) are discussed.

STUDIES ON FLUORESCENCE SPECTRA OF SAMARIUM EUROPIUM TERBIUM AND DYSPROSIUM WITH BENZOYL UREA DERIVATIVES AND PHENANTHROLINE

Rare earth chelates of benzoyl urea derivatives were prepared in ethanol and fluorescence spectra of these chelates were studied in detail. A composition of [RE(BU)_3Phen] (NO_3)_3 was obtained. Correlation between chemical properties of ligands, chelates and spectroscopy was discussed. Intramolecular energy transfer in rare earth chelates was explained.

Initiation Mechanism of Polymerization of Acryl－amide by Ceric Ion／2－Benzoyl Acetanilide System

he initiation mechanism of ceric ion/2-benzoyl acetanilide system was studiedby means of FT-IR, EPR and kinetic studies which revealed that 2-benzoyl ac-etanilide acts as a very active promotor to the polymerization initiated by ceric ion.The initiation mechanism was then proposed which involved the complex formationbetween a ceric ion and a l ,3-diketone group or a carbamate group, followed by,thedecomposition of the complex to generate C-centered secondary alkyl radical and N-centered anillido radical, both of which would initiate polymerization of vinylmonomer as the end groups of the polymers formed.

Extraction of trace thorium from hydrochloric acid media by 1-phenyl-3-methyl-4-benzoyl-5-pyrazolone

The paper describes the solvent extraction of trace thorium from hydrochloric acid media by1-phenyl-3-methyl-4-benzoyl-5-pyrazolone (PMBP) using a radioactive tracer technique. The percent extraction ofthorium was studied as a function of acidity, PMBP concentration and equilibrium time. The back-extraction behaviorof thorium from the organic phase was also tested. Separation of thorium was performed from fission products pro-duced in 14 MeV neutron bombardment of natural uranium by employing the PMBP extraction procedure. Thegamma-ray spectra of the separated thorium fractions show that thorium can be separated from most of fission prod-ucts and a large amount of uranium.

Extraction of Th(IV) from nitric acid with 4-benzoyl-2,4-dihydro-5-methyl-2-phenyl-3H-pyrazol-3-thione

The BMPPT (4-benzoyl-2,4-dihydro-5-methyl-2-phenyl-3H-pyrazol-3-thione)was synthesized from BMPP. Its m.p. is 106-108℃. The results of the element analysis are as follows: C, 68.51%, H, 4.51%, N, 9.26%, S, 11.47%, which are in conformity with the theoretical value (C, 69.15%, H, 4.76%, N, 9.52%, S, 10.90%). The solvent extraction of Th4+ from nitric acid solution by BMPPT in benzene was studied. The extraction ability of BMPPT is not so high as that of its parent (BMPP). The Th4+ distribution ratio (DTh) increases with the increasing pH of the aqueous phase, and pH1/2 for Th4+ was 3.2 ([BMPPT]=0.10 mol/L). When the pH increases, the distribution ratio of Th4+ increases linearly with the slope of 1 .59. When the concentration of BMPPT increases, the distribution ratio of Th4+ increases rapidly. The lgDTh-lg[BMPPT] is linear with the slope of 1.42 and the extraction mechanism is the cation ion-exchange.

Efficacy and Tolerability of 0.1%Adapalene With 1%Clindamycin Versus 0.1%Adapalene With 2.5%Benzoyl Peroxide on Acne Vulgaris:A Case Control Study

Objective:Combination therapy is currently the preferred acne treatment.We conducted this study to compare the efficacy and tolerability of 0.1%adapalene with 1%clindamycin versus 0.1%adapalene with 2.5%benzoyl peroxide(BPO)in the treatment of acne vulgaris.Methods:This study was conducted over a period of 1 year from September 2014 to September 2015.One-hundred patients aged 14 to 30 years with mild to moderate acne vulgaris were included.The patients were randomly allocated to 2 equal groups(n=50 in each group),and received a topical combination of 0.1%adapalene with 1%clindamycin andtopical combination of 0.1%adapalene with 2.5%BPO,respectively).The efficacy and tolerability of two treatments were compared.The unpaired studentt test was used to compare the difference in continuous variables between 2 groups,while the chi-square test or Fisher exact test was used for categorical variables.Results:One-hundred patients with mild to moderate acne vulgaris were randomly allocated to 2 equal groups(n=50 in each group).After 12 weeks of treatment,there were no significant differences between the adapalene-clindamycin and adapalene-BPO in the mean reductions in the numbers of non-inflammatory lesions(11.16±8.01 and 11.12±8.62,respectively),inflammatory papules(49.78±37.57 and 50.48±36.57,respectively),and total lesions(67.50±44.59 and 70.12±46.83,respectively).The incidence of a burning sensation was significantly greater in the adapalene-BPO group than the adapalene-clindamycin group(32%vs.6%;P=0.002).Conclusion:Topical adapalene plus clindamycin and adapalene plus BPO had similar efficacies in the treatment of acne.Adapalene with clindamycin was better tolerated than adapalene with BPO.