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Theoretical and experimental study of a bi-stable piezoelectric energy harvester under hybrid galloping and band-limited random excitations 被引量:1
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作者 Haitao LI Tianyu ZHENG +4 位作者 Weiyang QIN Ruilan TIAN Hu DING J.C.JI Liqun CHEN 《Applied Mathematics and Mechanics(English Edition)》 SCIE EI CSCD 2024年第3期461-478,共18页
In the practical environment,it is very common for the simultaneous occurrence of base excitation and crosswind.Scavenging the combined energy of vibration and wind with a single energy harvesting structure is fascina... In the practical environment,it is very common for the simultaneous occurrence of base excitation and crosswind.Scavenging the combined energy of vibration and wind with a single energy harvesting structure is fascinating.For this purpose,the effects of the wind speed and random excitation level are investigated with the stochastic averaging method(SAM)based on the energy envelope.The results of the analytical prediction are verified with the Monte-Carlo method(MCM).The numerical simulation shows that the introduction of wind can reduce the critical excitation level for triggering an inter-well jump and make a bi-stable energy harvester(BEH)realize the performance enhancement for a weak base excitation.However,as the strength of the wind increases to a particular level,the influence of the random base excitation on the dynamic responses is weakened,and the system exhibits a periodic galloping response.A comparison between a BEH and a linear energy harvester(LEH)indicates that the BEH demonstrates inferior performance for high-speed wind.Relevant experiments are conducted to investigate the validity of the theoretical prediction and numerical simulation.The experimental findings also show that strong random excitation is favorable for the BEH in the range of low wind speeds.However,as the speed of the incoming wind is up to a particular level,the disadvantage of the BEH becomes clear and evident. 展开更多
关键词 bi-stability inter-well response GALLOPING band-limited random
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Bi-stable states of initially stressed elastic cylindrical shell structures with two piezoelectric surface layers 被引量:1
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作者 Bin Wang Guo-Hua Nie 《Acta Mechanica Sinica》 SCIE EI CAS CSCD 2015年第5期653-659,共7页
A theoretical model is proposed in this paper to predict the bi-stable states of initially stressed cylindrical shell structures attached by surface anisotropic piezoelectric layers.The condition for existence of bi-s... A theoretical model is proposed in this paper to predict the bi-stable states of initially stressed cylindrical shell structures attached by surface anisotropic piezoelectric layers.The condition for existence of bi-stability of the shell structural system is presented and analytical expressions for corresponding rolled-up radii of the stable shell are given based on the principle of minimum strain energy.The resulting solution indicates that the shell system may have two stable configurations besides its initial state under a combined action of the actuating electric field and initial stresses characterized by the bending moment.If the piezoelectric layer materials act as only sensor materials without the actuating electric field,initial stresses may produce the bi-stable states,but one corresponding to its initial state.For the shell without initial stresses,the magnitude in the actuating electric field determines the number of the stable states,one or two stable configurations besides the initial state.The theoretical prediction for the bi-stable states is verified by finite element method(FEM) simulation by using the ABAQUS code. 展开更多
关键词 bi-stable Initial stress Cylindrical shell Piezoelectric layer Elastic potential energy Rolled-up radius Finite element
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An Investigation into the Isolation Performance of Mono-and Bi-stable Systems
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作者 Zeqi Lu Tiej un Yang +2 位作者 Michael J. Brennan Xinhui Li Zhigang Liu 《Journal of Marine Science and Application》 2014年第3期291-298,共8页
Motivated by the need for improving the isolation performance, many research studies have been performed on isolators with nonlinear characteristics. Based on the shape of their phase portrait, such devices can be con... Motivated by the need for improving the isolation performance, many research studies have been performed on isolators with nonlinear characteristics. Based on the shape of their phase portrait, such devices can be configured as either a mono-or bi-stable isolator. This paper focuses on investigating the relative performance of these two classes under the same excitations. Force transmissibility is used to measure the isolation performance, which is defined in terms of the RMS of the ratio of the transmitted force to the excitation force. When the system is subjected to harmonic excitation, it is found that the maximum reduction of the force transmissibility in the isolation range using Quasi-Zero stiffness is achieved. When the system is subjected to random excitation, it has the same effect of Quasi-Zero stiffness. Further, optimum damping can be changed with stiffness and has minimum value. 展开更多
关键词 nonlinear isolation bi-stable system force transmissibility random excitation mono-and bi-stable systems Quasi-Zero stiffness
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Transient transition behaviors of fractional-order simplest chaotic circuit with bi-stable locally-active memristor and its ARM-based implementation
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作者 Zong-Li Yang Dong Liang +2 位作者 Da-Wei Ding Yong-Bing Hu Hao Li 《Chinese Physics B》 SCIE EI CAS CSCD 2021年第12期88-101,共14页
This paper proposes a fractional-order simplest chaotic system using a bi-stable locally-active memristor.The characteristics of the memristor and transient transition behaviors of the proposed system are analyzed,and... This paper proposes a fractional-order simplest chaotic system using a bi-stable locally-active memristor.The characteristics of the memristor and transient transition behaviors of the proposed system are analyzed,and this circuit is implemented digitally using ARM-based MCU.Firstly,the mathematical model of the memristor is designed,which is nonvolatile,locally-active and bi-stable.Secondly,the asymptotical stability of the fractional-order memristive chaotic system is investigated and some sufficient conditions of the stability are obtained.Thirdly,complex dynamics of the novel system are analyzed using phase diagram,Lyapunov exponential spectrum,bifurcation diagram,basin of attractor,and coexisting bifurcation,coexisting attractors are observed.All of these results indicate that this simple system contains the abundant dynamic characteristics.Moreover,transient transition behaviors of the system are analyzed,and it is found that the behaviors of transient chaotic and transient period transition alternately occur.Finally,the hardware implementation of the fractional-order bi-stable locally-active memristive chaotic system using ARM-based STM32F750 is carried out to verify the numerical simulation results. 展开更多
关键词 fractional calculus bi-stable locally-active memristor transient transition behaviors ARM implementation
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Convergence Phenomenon with Fourier Series of tg(x2)and Alike
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作者 Alfred Wünsche 《Advances in Pure Mathematics》 2024年第7期556-595,共40页
The Fourier series of the 2π-periodic functions tg(x2)and 1sin(x)and some of their relatives (first of their integrals) are investigated and illustrated with respect to their convergence. These functions are Generali... The Fourier series of the 2π-periodic functions tg(x2)and 1sin(x)and some of their relatives (first of their integrals) are investigated and illustrated with respect to their convergence. These functions are Generalized functions and the convergence is weak convergence in the sense of the convergence of continuous linear functionals defining them. The figures show that the approximations of the Fourier series possess oscillations around the function which they represent in a broad band embedding them. This is some analogue to the Gibbs phenomenon. A modification of Fourier series by expansion in powers cosn(x)for the symmetric part of functions and sin(x)cosn−1(x)for the antisymmetric part (analogous to Taylor series) is discussed and illustrated by examples. The Fourier series and their convergence behavior are illustrated also for some 2π-periodic delta-function-like sequences connected with the Poisson theorem showing non-vanishing oscillations around the singularities similar to the Gibbs phenomenon in the neighborhood of discontinuities of functions. . 展开更多
关键词 Gibbs phenomenon Generalized Functions Weak Convergence Chebyshev Polynomials of First and Second Kind Even and Odd Generating Functions for Chebyshev Polynomials POLYLOGARITHMS Completeness Relations
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Overflowing phenomenon during ultrasonic treatment in Al-Si alloys 被引量:4
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作者 张宇博 卢一平 +3 位作者 接金川 傅莹 钟德水 李廷举 《Transactions of Nonferrous Metals Society of China》 SCIE EI CAS CSCD 2013年第11期3242-3248,共7页
At the late stage of solidification with ultrasonic treatment (UST) in Al-Si alloys, a part of semisolid overflows and climbs along the probe. The interesting phenomenon and its influence on the solidification micro... At the late stage of solidification with ultrasonic treatment (UST) in Al-Si alloys, a part of semisolid overflows and climbs along the probe. The interesting phenomenon and its influence on the solidification microstructure were investigated in order to better study the mechanism of UST. It is considered that the overflowing phenomenon occurs due to the changes of vibration and flow in the remaining semisolid. Because the overflowed portion comes from the region with intense UST effect and vibrates with the probe during solidification, great modification of primary and euteetic Si (about 10 pm in length) and refinement of primary a(Al) (about 70 μm in size) are observed in this portion. 展开更多
关键词 Al-Si alloy ultrasonic treatment overflowing phenomenon solidification microstructure
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INFLUENCE OF VIRTUAL PHOTON FIELD ON COLLAPSE AND REVIVAL PHENOMENON IN TWO PHOTON J C MODEL WITHOUT RWA
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作者 杨雁南 《Transactions of Nanjing University of Aeronautics and Astronautics》 EI 1999年第1期86-92,共7页
The time evolution of system in two photon Jaynes Cummings (J C) model without rotating waves approximation (RWA) is obtained by using the theory of ordinary differential equations. Based on the evolution, the mean ... The time evolution of system in two photon Jaynes Cummings (J C) model without rotating waves approximation (RWA) is obtained by using the theory of ordinary differential equations. Based on the evolution, the mean value of the atom inversion operator 〈 S 3(t)〉 is gi ven. The influence of the “counter rotating term” on the collapse and revival phenomenon is discussed from the comparison between the cases with RWA and without RWA. It shows that the influence of the virtual photon field makes the quantum fluctuations appear on the collapse and revival phenomenon. 展开更多
关键词 PHOTONS quantum noise J C model rotating waves approximation collapse and revival phenomenon atom inversion operator
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关于《纯粹理性批判》中“Appearance”与“Phenomenon”的翻译
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作者 刘蕴秋 傅小凡 《保定师专学报》 2000年第3期18-19,73,共3页
康德《纯粹理性批判》中“Appearance”与“Phenomenon”既存在本体论、认识论意义上的差异 ,又存在具体与抽象、变化规定与实体永恒。
关键词 康德 《纯粹理性批判》 "Appwearance" "Phwencmenon" 词义辨析 词语翻译
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Variational iteration solving method for El Nio phenomenon atmospheric physics of nonlinear model 被引量:14
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作者 MO Jiaqi WANG Hui +1 位作者 LIN Wantao LIN Yihua 《Acta Oceanologica Sinica》 SCIE CAS CSCD 2005年第5期35-38,共4页
A class of E1 Niйo atmospheric physics oscillation model is considered. The E1 Niйo atmospheric physics oscillation is an abnormal phenomenon involved in the tropical Pacific ocean-atmosphere interactions. The conce... A class of E1 Niйo atmospheric physics oscillation model is considered. The E1 Niйo atmospheric physics oscillation is an abnormal phenomenon involved in the tropical Pacific ocean-atmosphere interactions. The conceptual oscillator model should consider the variations of both the eastern and western Pacific anomaly patterns. An E1 Niйo atmospheric physics model is proposed using a method for the variational iteration theory. Using the variational iteration method, the approximate expansions of the solution of corresponding problem are constructed. That is, firstly, introducing a set of functional and accounting their variationals, the Lagrange multiplicators are counted, and then the variational iteration is defined, finally, the approximate solution is obtained. From approximate expansions of the solution, the zonal sea surface temperature anomaly in the equatorial eastern Pacific and the thermocline depth anomaly of the sea-air oscillation for E1 Niйo atmospheric physics model can be analyzed. E1 Niйo is a very complicated natural phenomenon. Hence basic models need to be reduced for the sea-air oscillator and are solved. The variational iteration is a simple and valid approximate method. 展开更多
关键词 NONLINEAR variational iteration method E1 Niйo phenomenon
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Genetic pattern of belt-wide petroliferous phenomenon in the eastern Pearl River Mouth Basin and its practical application 被引量:14
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作者 Shi Hesheng Dai Yiding +2 位作者 Liu Lihua Shu Yu Mei Lianfu 《Petroleum Science》 SCIE CAS CSCD 2014年第1期1-13,共13页
The Pearl River Mouth Basin (PRMB) covers an area of approximately 20× 104 km2.However,oil-gas fields detected in this area thus far are highly concentrated and controlled predominantly by second-order structur... The Pearl River Mouth Basin (PRMB) covers an area of approximately 20× 104 km2.However,oil-gas fields detected in this area thus far are highly concentrated and controlled predominantly by second-order structural belts,the seven largest of which aggregate proved oil reserves of 7.7× 108 m3,accounting for 86% of the total discovered reserve in the basin.These second-order structures have one common phenomenon:oil is contained in all traps present in them.In other words,they are all belt-wide petroliferous reservoirs.Research has identified eight types of second-order structural belts under two categories in the eastern PRMB.Their petroliferous properties are subject to three typical constraints:petroliferous properties of subsags hosting these structural belts,locations of these belts in the petroleum system,and availability of traps prior to the hydrocarbon expulsion and migration.The formation and distribution of oil reservoirs in these belts are characterized by subsag-belt integration and "three-in-one".The former indicates that sags and the second-order structural belts within the supply range of the sags constitute the basic units of hydrocarbon accumulations and are therefore inseparable.The latter indicates that a belt-wide petroliferous second-order structural belt always contains three important elements:hydrocarbon richness,effective pathway and pre-existing traps. 展开更多
关键词 Pearl River Mouth Basin belt-wide petroliferous phenomenon second-order structural belt petroleum exploration
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Effects of complement inhibition on the ABC phenomenon in rats 被引量:2
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作者 Lirong Wang Yuqing Su +6 位作者 Xuling Wang Kaifan Liang Mengyang Liu Wenya Tang Yanzhi Song Xinrong Liu Yihui Deng 《Asian Journal of Pharmaceutical Sciences》 SCIE CAS 2017年第3期250-258,共9页
Researchers reported that intravenously injected PEGylated colloidal drug carriers lose their long-circulating characteristic and accumulated extensively in liver when they are administrated twice in the same animal w... Researchers reported that intravenously injected PEGylated colloidal drug carriers lose their long-circulating characteristic and accumulated extensively in liver when they are administrated twice in the same animal with certain intervals. This phenomenon was referred to as the 'accelerated blood clearance(ABC) phenomenon'. Some former studies had found that complement-mediated phagocytosis, activated by antigen–antibody complex, was responsible for inducing the phenomenon. According to the theory, we have used cobra venom factor to deplete complement in vivo and to investigate the effect of complement inhibition on the ABC phenomenon. Rats were administered by injection of cobra venom factor solution to build up the model of complement exhaustion/inhibition, and the effect of the inhibition of complement on ABC phenomenon was carried out. It seemed that inhibition of complement didn’t affect the pharmacokinetic of the first infection. By contrast, in rats of which complement had been depleted, the second dose of PEGylated nanoemulsions showed enhanced circulation time compared with normal rats in a complement inhibition-independent manner, but the ABC phenomenon was not completely eliminated. It indicated that complement inhibition could certainly weaken the accelerated clearance;meanwhile, there were other factors causing the ABC effect.These findings provide novel insights into the attenuating of ABC phenomenon and lay foundation for further study of immune mechanism. 展开更多
关键词 ABC phenomenon PEGylated NANOEMULSIONS COMPLEMENT INHIBITION COBRA VENOM factor
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The effect of monosialylganglioside mix modifying the PEGylated liposomal epirubicin on the accelerated blood clearance phenomenon 被引量:3
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作者 Ting Zhang Songlei Zhou +5 位作者 Le Kang Xiang Luo Yang Liu Yanzhi Song Xinrong Liu Yihui Deng 《Asian Journal of Pharmaceutical Sciences》 SCIE CAS 2017年第2期134-142,共9页
PEGylated liposomes are potential candidates to improve the pharmacokinetic characteristics of encapsulated drugs, to extend their circulation half-life and facilitate their passive accumulation at tumour sites. Howev... PEGylated liposomes are potential candidates to improve the pharmacokinetic characteristics of encapsulated drugs, to extend their circulation half-life and facilitate their passive accumulation at tumour sites. However, PEG-modified liposomes can induce accelerated blood clearance(ABC) upon repeated administration, and the extent of ABC phenomenon on the cytotoxic drugs-containing PEGylated liposomes is related to the dose of the cytotoxic drugs.In this study, EPI served as a model cytotoxic drug, a hydrophilic surfactant molecule,monosialylganglioside(GM1) was chosen and modified on the liposomes together with PEG.It was shown that upon mixed modification, when GM1 contents reached 10% or 15% mol,the ABC phenomenon of the PEGylated liposomal EPI significantly reduced. We also found that GM1 played an important role in abrogating the ABC phenomenon in both the induction phase and the effectuation phase. The results suggested that GM1 incorporation unfortunately did not avoid occurrence of ABC phenomenon completely, but GM1 modification on PEGylated liposomes may provide a significant improvement in clinical practice of PEGylated liposomes. Further study must be necessary. 展开更多
关键词 PEGylated liposomes EPIRUBICIN Monosialylganglioside(GM1) Mixed modification Accelerated blood CLEARANCE (ABC) phenomenon
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Melting phenomenon in magneto hydro-dynamics steady flow and heat transfer over a moving surface in the presence of thermal radiation 被引量:2
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作者 Reda G.Abdel-Rahman M.M.Khader Ahmed M.Megahed 《Chinese Physics B》 SCIE EI CAS CSCD 2013年第3期57-62,共6页
The Lie group method is applied to present an analysis of the magneto hydro-dynamics(MHD) steady laminar flow and the heat transfer from a warm laminar liquid flow to a melting moving surface in the presence of ther... The Lie group method is applied to present an analysis of the magneto hydro-dynamics(MHD) steady laminar flow and the heat transfer from a warm laminar liquid flow to a melting moving surface in the presence of thermal radiation.By using the Lie group method,we have presented the transformation groups for the problem apart from the scaling group.The application of this method reduces the partial differential equations(PDEs) with their boundary conditions governing the flow and heat transfer to a system of nonlinear ordinary differential equations(ODEs) with appropriate boundary conditions.The resulting nonlinear system of ODEs is solved numerically using the implicit finite difference method(FDM).The local skin-friction coefficients and the local Nusselt numbers for different physical parameters are presented in a table. 展开更多
关键词 Lie group method magneto hydro-dynamics melting phenomenon Newtonian fluid radiation
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Relatedness between catalytic effect of activated carbon and passivation phenomenon during chalcopyrite bioleaching by mixed thermophilic Archaea culture at 65°C 被引量:5
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作者 Ya-long MA Hong-chang LIU +7 位作者 Jin-lan XIA Zhen-yuan NIE Hong-rui ZHU Yi-dong ZHAO Chen-yan MA Lei ZHENG Cai-hao HONG Wen WEN 《Transactions of Nonferrous Metals Society of China》 SCIE EI CAS CSCD 2017年第6期1374-1384,共11页
The relatedness between catalytic effect of activated carbon and passivation phenomenon during chalcopyrite bioleachingby mixed thermophilic Archaea culture(Acidianus brierleyi,Metallosphaera sedula,Acidianus manzaens... The relatedness between catalytic effect of activated carbon and passivation phenomenon during chalcopyrite bioleachingby mixed thermophilic Archaea culture(Acidianus brierleyi,Metallosphaera sedula,Acidianus manzaensis and Sulfolobusmetallicus)at65°C was studied.Leaching experiments showed that the addition of activated carbon could significantly promote thedissolution of chalcopyrite for both bioleaching and chemical leaching.The results of synchrotron-based X-ray diffraction,ironL-edge and sulfur K-edge X-ray absorption near edge structure spectroscopy indicated that activated carbon could change thetransition path of electrons through galvanic interactions to form more readily dissolved secondary mineral chalcocite at a low redoxpotential(?400mV)and then enhanced the copper dissolution.Jarosite accumulated immediately in the initial stage of bioleachingwith activated carbon but copper dissolution was not hindered.However,much jarosite precipitated on the surface of chalcopyrite inthe late stage of bioleaching,which might account for the decrease of copper dissolution rate.More elemental sulfur(S0)was alsodetected with additional activated carbon but the mixed thermophilic Archaea culture had a great sulfur oxidation activity,thus S0waseliminated and seemed to have no significant influence on the dissolution of chalcopyrite. 展开更多
关键词 CHALCOPYRITE BIOLEACHING activated carbon passivation phenomenon mixed thermophilic Archaea culture
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The accelerated blood clearance phenomenon of PEGylated nanoemulsion upon cross administration with nanoemulsions modified with polyglycerin 被引量:1
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作者 Yuqing Su Lirong Wang +4 位作者 Kaifan Liang Mengyang Liu Xinrong Liu Yanzhi Song Yihui Deng 《Asian Journal of Pharmaceutical Sciences》 SCIE CAS 2018年第1期44-53,共10页
For investigating the accelerated blood clearance(ABC) phenomenon of polyglycerin modified nanoemulsions upon cross administration with polyethylene glycol(PEG) covered nanoemulsion, we used the 1,2-distea-royl-sn-gly... For investigating the accelerated blood clearance(ABC) phenomenon of polyglycerin modified nanoemulsions upon cross administration with polyethylene glycol(PEG) covered nanoemulsion, we used the 1,2-distea-royl-sn-glycero-3-phosphoethanolamine-npolyglycerine-610 and the 1,2-distearoyl-n-glycero-3-phosphoethanolamine-n-[methoxy(polyethylene glycol)-2000] as modify materials, the dialkylcarbocyanines as fluorescence indicator. Exhausted macrophages rat model was established and new material containing polycarboxyl structure was synthesized. The microplate reader and the in vivo optical imaging system were applied to measure the concentration of nanoemulsions in tissues.The results show that the first dose of polyglycerin modified nanoemulsion can induce the ABC phenomenon of the second dose of PEGylated nanoemulsion. With the increase in the amount of the surface polyglycerin, the extent of the ABC phenomenon decreases. Liver accumulation has positive relationship with the ABC phenomenon. Furthermore, kupffer cells in liver can get more immune information from polyhydroxy structure than polycarboxyl group in the modify compound. The results of our work imply that the polycarboxyl structure has advantages to eliminate the ABC phenomenon. 展开更多
关键词 ABC phenomenon NANOEMULSION LIVER ACCUMULATION KUPFFER cells Polyglycerin Polycarboxyl
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Optimization of Baffled Rectangular and Prismatic Storage Tank Against the Sloshing Phenomenon 被引量:7
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作者 Hassan SAGHI NING De-zhi +1 位作者 CONG Pei-wen ZHAO Ming 《China Ocean Engineering》 SCIE EI CSCD 2020年第5期664-676,共13页
The fluid motion in partially filled tanks with internal baffles has wide engineering applications. The installation of baffles is expected to reduce the effect of sloshing as well as the consequent environmental dama... The fluid motion in partially filled tanks with internal baffles has wide engineering applications. The installation of baffles is expected to reduce the effect of sloshing as well as the consequent environmental damages. In the present study, a series of experimental tests are performed to investigate the sloshing phenomenon in a baffled rectangular storage tank. In addition, the sloshing phenomenon is also modeled by using Open Foam. Based on the experimental and numerical studies, optimization of the geometric parameters of the tank is performed based on some criteria such as tank area, entropy generation, and the horizontal force exerted on the tank area due to the sloshing phenomenon.The optimization is also carried out based on the entropy generation minimization analysis. It is noted that the optimum baffle height is in the range of h_b/h_w=0.5-0.75 in the present study(where h_b and h_w are the baffle height and water depth, respectively). Based on the results, the optimal design of the tank is achieved with R_A= 0.9-1.0(where R_A=L/W, L and W are the length and width of the tank, respectively). The results also show that the increase of h_b can lead to a decrease of the maximum pressure and horizontal force exerted on the tank. It is also noted that the horizontal force exerted on the tank firstly continues to increase as the sway motion amplitude increases.However, as the normalized motion amplitude parameter, a/L(The parameter a is the motion amplitude), exceeds0.067, the effect of motion amplitude on the force is not obvious. The same optimization is also performed in the multiple-variable-baffled tank and prismatic storage tank. 展开更多
关键词 baffled rectangular storage tank experimental tests sloshing phenomenon OPTIMIZATION entropy generation Open Foam
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Anticipation phenomenon in familial adenomatous polyposis:an analysis of its origin 被引量:1
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作者 Takeo Iwama Joji Utsunomiya 《World Journal of Gastroenterology》 SCIE CAS CSCD 2000年第3期335-338,共4页
AIM To analyze the origin of the anticipationphenomenon,which means earlier death insuccessive generation in familial adenomatouspolyposis.METHODS The study subjects were 2161patients with familial adenomatous polypos... AIM To analyze the origin of the anticipationphenomenon,which means earlier death insuccessive generation in familial adenomatouspolyposis.METHODS The study subjects were 2161patients with familial adenomatous polyposisand their 7465 first-degree relatives who weremembers of 750 families registered at ourPolyposis Registry.The ages at death andcumulative mortality rates in the parent,theproband,and the child generations werecompared for both all subjects and the patientsalone.RESULTS In the patients over 5 years of age,the mean age at death was 50.9 years for theparent,42.3 years for the proband,and 33.3years for the child generations,respectively(P【0.001).The deceased rates in the threegenerations were 90.7%,51.3% and 23.1% ofthe patients,respectively,and this differencewas the main cause of the anticipation measuredby parent-child paring method.The cumulativemortality rates for all subjects failed to showanticipation,however the cumulative mortalityrates for the patients showed the anticipation.The anticipation phenomenon was shown by anyparent-child pairing methods for the deceasedpatients.Other important causes of theanticipation were different proportion of causesof death between generations(P【0.001),and alow proportion of detected or deceased patients (P【0.001)in the child generation.CONCLUSION Anticipation in familialadenomatous polyposis may be caused byparent-child paring methods as well as severalintergenerational biases. 展开更多
关键词 FAMILIAL adenomatous apolyposis (FAP) ANTICIPATION phenomenon INTERGENERATIONAL bias child generations HEREDITARY DISORDER mortality
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Effect of Kupffer cells depletion on ABC phenomenon induced by Kupffer cells-targeted liposomes 被引量:1
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作者 Chaoyang Lai Cong Li +6 位作者 Mengyang Liu Qiujun Qiu Xiang Luo Xinrong Liu Ling Hu Yihui Deng Yanzhi Song 《Asian Journal of Pharmaceutical Sciences》 SCIE CAS 2019年第4期455-464,共10页
Accelerated blood clearance(ABC) phenomenon is common in many PEGylated nanocarriers, whose mechanism has not been completely elucidated yet. In this study, the correlation between Kupffer cells(KCs) and ABC phenomeno... Accelerated blood clearance(ABC) phenomenon is common in many PEGylated nanocarriers, whose mechanism has not been completely elucidated yet. In this study, the correlation between Kupffer cells(KCs) and ABC phenomenon has been studied by KCs-targeted liposomes inducing ABC phenomenon and KCs depletion. In other words, the 4-aminophenyl-α-D-mannopyranoside(APM) lipid derivative DSPE-PEG 2000-APM(DPM), and 4-aminophenyl-β-L-fucopyranoside(APF) lipid derivative DSPE-PEG 2000-APF(DPF) were conjugated and modified on alendronate sodium(AD) liposomes to specifically target and deplete KCs. The dualligand modified PEGylated liposomes(MFPL) showed stronger ability to damage KCs in vitro and in vivo, which also could indirectly illustrate that dual-ligand modification could better target KCs. Besides, the hepatic biodistribution and pharmacokinetics could directly prove that MFPL had a stronger targeting ability to KCs. In addition, in depletion rats, plasma concentration and splenic biodistribution of MFPL and PEGylated liposomes(PL) were significantly elevated and hepatic biodistribution was significantly reduced, which demonstrated that KCs played an important role on elimination of nanoparticles. What’s more, ABC phenomenon of the secondary injection of PL was stronger in KCs depletion rats than that in normal rats, which indicated that depletion of KCs prolonged the circulation of PL in the first injection repeatedly stimulating B-cells in the marginal region of the spleen and causing it to secrete more IgM antibodies. This could also illustrate that anti-PEG IgM takes up a major station compared with KCs. Most important of all, KCs-targeted liposomes could induce a stronger ABC phenomenon than PL in normal rats, which declared that based on the same IgM concentration, the more the KCs were stimulated, the stronger ABC phenomenon was induced. However, in depletion rats, this difference of ABC phenomenon between PL and MFPL could no more exist, further demonstrating that KCs could participate and play a certain role in the ABC phenomenon. 展开更多
关键词 ACCELERATED BLOOD CLEARANCE (ABC) phenomenon KUPFFER cells Depletion Liposomes Bio-distribution
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Dissymmetric flow phenomenon in a multistrand tundish 被引量:1
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作者 Mingmei Zhu Guanghua Wen Ping Tang Yufeng Wang 《Journal of University of Science and Technology Beijing》 CSCD 2007年第6期490-494,共5页
The dissymmetric flow phenomenon exists in a symmetric multistrand tundish. It was studied by the physical simulation experiment. The fundamental flow characteristic of dissymmetry was analyzed. The asymmetry of the f... The dissymmetric flow phenomenon exists in a symmetric multistrand tundish. It was studied by the physical simulation experiment. The fundamental flow characteristic of dissymmetry was analyzed. The asymmetry of the flow field, the temperature field, and the inclusions distribution without flow-control devices (FCDs) were compared with those with FCDs. It is proved that the asymmetry of the flow and temperature field along the outlets at the long range is more obvious. The symmetric FCDs installation has a slight effect on the dissymmetric temperature field, simultaneously, the symmetry of the average residence time and the fluid flow pattern has improved, and the fluid flow in the tundish has been more reasonable. In case of a symmetric multistrand tundish having a large volume, the influence of the dissymmetric phenomenon should be considered and the flow behaviors in the whole tundish should be studied completely. 展开更多
关键词 multistrand tundish dissymmetry flow phenomenon physical simulation flow-control devices
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Research on the Freezing Phenomenon of Quantum Correlation by Machine Learning 被引量:3
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作者 Xiaoyu Li Qinsheng Zhu +6 位作者 Yiming Huang Yong Hu Qingyu Meng Chenjing Su Qing Yang Shaoyi Wu Xusheng Liu 《Computers, Materials & Continua》 SCIE EI 2020年第12期2143-2151,共9页
Quantum correlation shows a fascinating nature of quantum mechanics and plays an important role in some physics topics,especially in the field of quantum information.Quantum correlations of the composite system can be... Quantum correlation shows a fascinating nature of quantum mechanics and plays an important role in some physics topics,especially in the field of quantum information.Quantum correlations of the composite system can be quantified by resorting to geometric or entropy methods,and all these quantification methods exhibit the peculiar freezing phenomenon.The challenge is to find the characteristics of the quantum states that generate the freezing phenomenon,rather than only study the conditions which generate this phenomenon under a certain quantum system.In essence,this is a classification problem.Machine learning has become an effective method for researchers to study classification and feature generation.In this work,we prove that the machine learning can solve the problem of X form quantum states,which is a problem of physical significance.Subsequently,we apply the density-based spatial clustering of applications with noise(DBSCAN)algorithm and the decision tree to divide quantum states into two different groups.Our goal is to classify the quantum correlations of quantum states into two classes:one is the quantum correlation with freezing phenomenon for both Rènyi discord(α=2)and the geometric discord(Bures distance),the other is the quantum correlation of non-freezing phenomenon.The results demonstrate that the machine learning method has reasonable performance in quantum correlation research. 展开更多
关键词 Machine learning quantum correlation freezing phenomenon Rènyi discord geometric discord
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