Combined Selection Index for New Yorkshire Dam Line with High Prolificacy

The combined selection index used in the breeding of new Yorkshire dam line with high prolificacy according to breeding objects was formulated as /：2.272E- BVNB-0.056EBVDAYS. After 5 generations breeding, the two main selected traits such as total number of born and age at 100 kg weight was 12.17 piglets/litter and 165.18 d, respectively. The genetic improvements per generates was 0.156 and -2.198, respec- tively. The breeding objects of the new Yorkshire dam line with high prolificacy were basically reached. It indicated that the methods and index could be used in pig breeding.

THE ANTAGONISTIC EFFECTS OF TETRAHYDRO-PROTOBERBERINES ON DOPAMINE RECEPTORS: ELECTROPHYSIOLOGICAL STUDIES

Tetrahydroprotoberberines (THPBs), including (-)-stepholidine ((-)-SPD), (-)-tetrahydropalmatine ((-)-THP) and tetrahydroberberine (THB), have been demonstrated to be a new class of DA antagonists in biochemical and neuropharmacological studies. In this paper, the antagonistic action of THPBs was examined by means of single unit recording from nigral DA neuron in chloral hydrate-anesthetized and gallamine-paralyzed rats. Intravenous injection of these compounds could promptly and completely reverse the inhibition of the spontaneous firing induced by DA agonist apomorphine (APO) in a dose-dependent way. Pretreatment with (-)-SPD, (-)-THP or THB could significantly reduce the inhibitory effect of APO and shift the dose-action curve to the right. Besides, the compounds could increase the spontaneous firing of DA neurons. The above results not only strongly support the conclusion that (-)-SPD, (-)-THP and THB are DA antagonists, but also demonstrate that one of their blocking sites is at somatodendritic DA autoreceptors (D-2 receptors). In other words, (-)-SPD did not exhibit any DA agonistic action in this acute electrophysiological study, although its DA agonistic action can be demonstrated in rotational behavior of 6-oHDA-lesioned rats. The dual actions of (-)-SPD, dependent upon different experimental conditions, are discussed.

Design and analysis of annular combustion chamber of a low bypass turbofan engine in a jet trainer aircraft

The design of an annular combustion chamber in a gas turbine engine is thebackbone of this paper.It is specifically designed for a low bypass turbofan engine in a jettrainer aircraft.The combustion chamber is positioned in between the compressor and turbine.lt has to be designed based on the constant pressure,enthalpy addition process.The presentmethodology deals with the computation of the initial design parameters from benchmarking ofreal-time industry standards and arriving at optimized values.It is then studied for feasibilityand finalized.Then the various dimensions of the combustor are calculated based on differentempirical formulas.The air mass flow is then distributed across the zones of the combustor.The cooling requirement is met using the cooling holes.Finally the variations of parameters atdifferent points are calculated.The whole combustion chamber is modeled using Siemens NX8.0,a modeling software and presented.The model is then analyzed using various parametersat various stages and levels to determine the optimized design.The aerodynamic flowcharacteristics is simulated numerically by means of ANSYS 14.5 software suite.The air-fuelmixture,combustion-turbulence,thermal and cooling analysis is carried out.The analysis isperformed at various scenarios and compared.The results are then presented in image outputsand graphs.

Growth of gas bubbles in the biotissues with convective acceleration

This paper presents formulae and explanation about the growth of a convective gas bubble in the blood and other tissues of divers who surface too quickly, concentration distribution around the growing bubble is also presented. The formulae are valid all over the growth stages, i.e. under variable ambient pressure while the diver is ascending, and under constant ambient pressure at diving stops or at sea level. The mathematical model is solved analytically by using the method of combined variables. The growth process is affected by tissue diffusivity, concentration constant and the initial void fraction, which is the dominant parameter. Results show that, the time of the complete growth, in the convective growth model, is shorter than those earlier presented by Mohammadein and Mohamed [Concentration distribution around a growing gas bubble in tissue, Math. Biosci. 225（1） （2010） 11-17] and Srinivasan et al. [Mathematical models of diffusion- limited gas bubble dynamics in tissue, J. Appl. Physiol. 86 （1999） 732-741] for the growth of a stationary gas bubble, this explains the effect of bubble motion on consuming the oversaturated dissolved gas from the tissue into growing bubble which leads to increment in the growth rate to be more than those presented in the previous stationary models.