Homopolymers of L-amino acids such as poly(L-glutamic acid) and poly (Llysine) not only have good biocompatibility and biodegradability, but also lack of immunogenicity. It has been reported that homopoly(L-amino acid...Homopolymers of L-amino acids such as poly(L-glutamic acid) and poly (Llysine) not only have good biocompatibility and biodegradability, but also lack of immunogenicity. It has been reported that homopoly(L-amino acids) were used as the carriers of antitumor drugs such as mustard, methotrexate (MTX), cyclophosphamide, daunomycin(DM) and adriamycin (ADR). 5-Fluorouracil(5-FU) is most useful for the treatment of patients with carcinoma of the breast and gastrointestinal展开更多
文摘Homopolymers of L-amino acids such as poly(L-glutamic acid) and poly (Llysine) not only have good biocompatibility and biodegradability, but also lack of immunogenicity. It has been reported that homopoly(L-amino acids) were used as the carriers of antitumor drugs such as mustard, methotrexate (MTX), cyclophosphamide, daunomycin(DM) and adriamycin (ADR). 5-Fluorouracil(5-FU) is most useful for the treatment of patients with carcinoma of the breast and gastrointestinal
