Over the past 30 years,additive manufacturing(AM)has developed rapidly and has demonstrated great potential in biomedical applications.AM is a materials-oriented manufacturing technology,since the solidification mecha...Over the past 30 years,additive manufacturing(AM)has developed rapidly and has demonstrated great potential in biomedical applications.AM is a materials-oriented manufacturing technology,since the solidification mechanism,architecture resolution,post-treatment process,and functional application are based on the materials to be printed.However,3D printable materials are still quite limited for the fabrication of bioimplants.In this work.2D/3D AM materials for bioimplants are reviewed.Furthermore,inspired by Tai Chi,a simple yet novel soft/rigid hybrid 4D AM concept is advanced to develop complex and dynamic biological structures in the human body based on 4D printing hybrid ceramic precursor/ceramic materials that were previously developed by our group.With the development of multi-material printing technology,the development of bioimplants and soft/rigid hybrid biological structures with 2D/3D/4D AM materials can be anticipated.展开更多
Bioimplants are becoming increasingly impor-tant in the modem society due to the fact of an agingpopulation and associated issues of osteoporosis andosteoarthritis. The manufacturing of bioimplants involvesan understa...Bioimplants are becoming increasingly impor-tant in the modem society due to the fact of an agingpopulation and associated issues of osteoporosis andosteoarthritis. The manufacturing of bioimplants involvesan understanding of both mechanical engineering andbiomedical science to produce biocompatible products withadequate lifespans. A suitable selection of materials is theprerequisite for a long-term and reliable service of thebioimplants, which relies highly on the comprehensiveunderstanding of the material properties. In this paper,most biomaterials used for bioimplants are reviewed. Thetypical manufacturing processes are discussed in order toprovide a perspective on the development of manufacturingfundamentals and latest technologies. The review alsocontains a discussion on the current measurement andevaluation constraints of the finished bioimplant products.Potential future research areas are presented at the end ofthis paper.展开更多
The manufacturing of bioimplants not only involves selecting proper biomaterials with satisfactory bulk physicochemical properties, but also requires special treatments on surface chemistry or topography to direct a d...The manufacturing of bioimplants not only involves selecting proper biomaterials with satisfactory bulk physicochemical properties, but also requires special treatments on surface chemistry or topography to direct a desired host response. The lifespan of a bioimplant is also critically restricted by its surface properties. Therefore, developing proper surface treatment technologies has become one of the research focuses in biomedical engineering. This paper covers the recent progress of surface treatment of bioimplants from the aspects of coating and topography modification. Pros and cons of various tech- nologies are discussed with the aim of providing the most suitable method to be applied for different biomedical products. Relevant techniques to evaluate wear, corrosion and other surface properties are also reviewed.展开更多
Hydroxyapatite (HA) is effectively used as a bioimplant material because it closely resembles bone apatite and exhibits good biocompatibility. This paper describe synthesis technique of HA powder by sol-gel method. Th...Hydroxyapatite (HA) is effectively used as a bioimplant material because it closely resembles bone apatite and exhibits good biocompatibility. This paper describe synthesis technique of HA powder by sol-gel method. The product was sintered twice at two different temperatures 400°C to 750°C to improve its crystallinity. The final powder sintered at two temperatures was characterized by X-ray analysis, Scanning electron microscopy (SEM) and Fourier Transform Infrared Spectroscopy (FT-IR) to reveal its phase content, morphology and types of bond present within it. Thermal analysis (TG–DTA) was carried out to investigate the thermal stability of the powder.展开更多
基金This work was supported by the National Key R&D Program of China(2017YFA0204403)the Major Program of the National Natural Science Foundation of China(51590892)+3 种基金the General Research Fund Research Grants Council(Hong Kong)(CityU 11209918)the Hong Kong Collaborative Research Fund Scheme(C4026-17W)the Hong Kong Theme-based Research Scheme(T13-402/17-N)the Shenzhen-Hong Kong cooperation zone for technology and innovation(HZQB-KCZYB-2020030).
文摘Over the past 30 years,additive manufacturing(AM)has developed rapidly and has demonstrated great potential in biomedical applications.AM is a materials-oriented manufacturing technology,since the solidification mechanism,architecture resolution,post-treatment process,and functional application are based on the materials to be printed.However,3D printable materials are still quite limited for the fabrication of bioimplants.In this work.2D/3D AM materials for bioimplants are reviewed.Furthermore,inspired by Tai Chi,a simple yet novel soft/rigid hybrid 4D AM concept is advanced to develop complex and dynamic biological structures in the human body based on 4D printing hybrid ceramic precursor/ceramic materials that were previously developed by our group.With the development of multi-material printing technology,the development of bioimplants and soft/rigid hybrid biological structures with 2D/3D/4D AM materials can be anticipated.
文摘Bioimplants are becoming increasingly impor-tant in the modem society due to the fact of an agingpopulation and associated issues of osteoporosis andosteoarthritis. The manufacturing of bioimplants involvesan understanding of both mechanical engineering andbiomedical science to produce biocompatible products withadequate lifespans. A suitable selection of materials is theprerequisite for a long-term and reliable service of thebioimplants, which relies highly on the comprehensiveunderstanding of the material properties. In this paper,most biomaterials used for bioimplants are reviewed. Thetypical manufacturing processes are discussed in order toprovide a perspective on the development of manufacturingfundamentals and latest technologies. The review alsocontains a discussion on the current measurement andevaluation constraints of the finished bioimplant products.Potential future research areas are presented at the end ofthis paper.
文摘The manufacturing of bioimplants not only involves selecting proper biomaterials with satisfactory bulk physicochemical properties, but also requires special treatments on surface chemistry or topography to direct a desired host response. The lifespan of a bioimplant is also critically restricted by its surface properties. Therefore, developing proper surface treatment technologies has become one of the research focuses in biomedical engineering. This paper covers the recent progress of surface treatment of bioimplants from the aspects of coating and topography modification. Pros and cons of various tech- nologies are discussed with the aim of providing the most suitable method to be applied for different biomedical products. Relevant techniques to evaluate wear, corrosion and other surface properties are also reviewed.
文摘Hydroxyapatite (HA) is effectively used as a bioimplant material because it closely resembles bone apatite and exhibits good biocompatibility. This paper describe synthesis technique of HA powder by sol-gel method. The product was sintered twice at two different temperatures 400°C to 750°C to improve its crystallinity. The final powder sintered at two temperatures was characterized by X-ray analysis, Scanning electron microscopy (SEM) and Fourier Transform Infrared Spectroscopy (FT-IR) to reveal its phase content, morphology and types of bond present within it. Thermal analysis (TG–DTA) was carried out to investigate the thermal stability of the powder.
