Rising role of artificial intelligence in image reconstruction for biomedical imaging

In this editorial,we review recent progress on the applications of artificial intelligence(AI)in image reconstruction for biomedical imaging.Because it abandons prior information of traditional artificial design and adopts a completely data-driven mode to obtain deeper prior information via learning,AI technology plays an increasingly important role in biomedical image reconstruction.The combination of AI technology and the biomedical image reconstruction method has become a hotspot in the field.Favoring AI,the performance of biomedical image reconstruction has been improved in terms of accuracy,resolution,imaging speed,etc.We specifically focus on how to use AI technology to improve the performance of biomedical image reconstruction,and propose possible future directions in this field.

OBIA:An Open Biomedical Imaging Archive

With the development of artificial intelligence(AI)technologies,biomedical imaging data play an important role in scientific research and clinical application,but the available resources are limited.Here we present Open Biomedical Imaging Archive(OBIA),a repository for archiving biomedical imaging and related clinical data.OBIA adopts five data objects(Collection,Individual,Study,Series,and Image)for data organization,and accepts the submission of biomedical images of multiple modalities,organs,and diseases.In order to protect personal privacy,OBIA has formulated a unified de-identification and quality control process.In addition,OBIA provides friendly and intuitive web interfaces for data submission,browsing,and retrieval,as well as image retrieval.As of September 2023,OBIA has housed data for a total of 937 individuals,4136 studies,24,701 series,and 1,938,309 images covering 9 modalities and 30 anatomical sites.Collectively,OBIA provides a reliable platform for biomedical imaging data management and offers free open access to all publicly available data to support research activities throughout the world.OBIA can be accessed at https://ngdc.cncb.ac.cn/obia.

High sensitivity and high selectivity terahertz biomedical imaging

We demonstrate two distinct emerging terahertz （THz） biomedical imaging techniques.One is based on the use of a new single frequency THz quantum cascade laser and the other is based on broadband THz time domain spectrocopy.The first method is employed to derive a metastasis lung tissue imaging at 3.7 THz with clear contrast between cancerous and healthy areas.The second approach is used to study an osseous tissue under several imaging modalities and achieve full THz spectroscopic imaging based on the frequency domain or on a fixed THz propagation time-delay.Sufficient contrast is achieved which facilitated the identification of regions with different cellular types and density compositions.

Biomedical microwave-induced thermoacoustic imaging

Microwave induced thermoacoustic imaging(MTAI)has emerged as a potential biomedical imaging modality with over 20-year growth.MTAI typically employs pulsed microwave as the pumping source,and detects the microwave-induced ultrasound wave via acoustic transducers.Therefore,it features high acoustic resolution,rich elect romagnetic contrast,and large imaging depth.Benefiting from these unique advantages,MTAI has been extensively applied to various fields including pathology,biology,material and medicine.Till now,MTAI has been deployed for a wide range of biomedical applications,including cancer diagnosis,joint evaluation,brain in-vestigation and endoscopy.This paper provides a comprehensive review on(1)essential physics(endogenous/exogenous contrast mechanisms,penetration depth and resolution),(2)hardware configurations and software implementations(excit ation source,antenna,ultrasound detector and image recovery algorithm),(3)animal studies and clinical applications,and(4)future directions.

Self-powered and broadband germanium/PEDOT:PSS heterojunction photodetectors for near-infrared biomedical imaging applications

To develop high-performance photodetectors(PDs) as near-infrared(NIR) imaging sensors, researchers have either proposed new photoelectric materials, introduced complicated interface-processing steps, or created complex optical structures. In this study, we introduce a solution-processed organic material, PEDOT:PSS(PEDOT corresponds to a polymer of 3,4-ethylene dioxythiophene(EDOT), and PSS corresponds to a polystyrene sulfonate), to germanium(Ge) wafers using a convenient spincoating method to improve the photoresponse performance of Ge-based PDs. The Ge wafers and PEDOT:PSS form a heterojunction that reduces the dark current when compared with the Ge Schottky PD(Au/Ge/Ag PD). The experimental results show that the Au/PEDOT:PSS/Ge/Ag heterojunction PD with a bias voltage of 0 V at 1550 nm exhibits a responsivity(R) of 0.26 A/W,a detectivity(D*) of 6.5×1011 Jones, a linear dynamic range(LDR) of 124 d B, and a bandwidth(-3 dB) of 10 k Hz. This implies that the performance of the PD is comparable to that of previously reported Ge-based PDs. Subsequently, a biomedical imaging application of the PD is successfully demonstrated through foreign-body detection. Therefore, it is expected that the selfpowered Au/PEDOT:PSS/Ge/Ag PD will be highly suitable for NIR imaging.

Recent development on peptide-based probes for multifunctional biomedical imaging

Peptide-based probes play prominent roles in biomedical research due to their promising properties such as high biocompatibility,fast excretion, favorable pharmacokinetics as well as easy and robust preparation. Considering the translation of imaging probes into clinical applications, peptide-based probes remain to be the most desirable and optimal candidates. This review summarized the development of peptide-based probes with promising imaging modalities and highlighted the successful applications for in vivo biomedical imaging.

Automated Deep Learning Based Melanoma Detection and Classification Using Biomedical Dermoscopic Images

Melanoma remains a serious illness which is a common formof skin cancer.Since the earlier detection of melanoma reduces the mortality rate,it is essential to design reliable and automated disease diagnosis model using dermoscopic images.The recent advances in deep learning(DL)models find useful to examine the medical image and make proper decisions.In this study,an automated deep learning based melanoma detection and classification(ADL-MDC)model is presented.The goal of the ADL-MDC technique is to examine the dermoscopic images to determine the existence of melanoma.The ADL-MDC technique performs contrast enhancement and data augmentation at the initial stage.Besides,the k-means clustering technique is applied for the image segmentation process.In addition,Adagrad optimizer based Capsule Network(CapsNet)model is derived for effective feature extraction process.Lastly,crow search optimization(CSO)algorithm with sparse autoencoder(SAE)model is utilized for the melanoma classification process.The exploitation of the Adagrad and CSO algorithm helps to properly accomplish improved performance.A wide range of simulation analyses is carried out on benchmark datasets and the results are inspected under several aspects.The simulation results reported the enhanced performance of the ADL-MDC technique over the recent approaches.

Automated classification of dual channel dental imaging of auto-fluorescence and white lightby convolutional neural networks

Prevention is the most effective way to reduce dental caries.In order to provide a simple way to achieve oral healthcare direction in daily life,dual Channel,portable dental Imaging system that combine white light with autofluorescence techniques was established,and then,a group of volunteers were recruited,7200 tooth pictures of different dental caries stage and dental plaque were taken and collected.In this work,a customized Convolutional Neural Networks(CNNs)have been designed to classify dental image with early stage caries and dental plaque.Eighty percentage(n=6000)of the pictures taken were used to supervised training of the CNNs based on the experienced dentists'advice and the rest 20%(n=1200)were used to a test dataset to test the trained CNNs.The accuracy,sensitivity and specificity were calculated to evaluate perfor-mance of the CNNs.The accuracy for the early stage caries and dental plaque were 95.3%and 95.9%,respectively.These results shown that the designed image system combined the cus-tomized CNNs that could automatically and efficiently find early caries and dental plaque on occlusal,lingual and buccal surfaces.Therefore,this will provide a novel approach to dental caries prevention for everyone in daily life.

Intelligent Classification Model for Biomedical Pap Smear Images on IoT Environment

Biomedical images are used for capturing the images for diagnosis process and to examine the present condition of organs or tissues.Biomedical image processing concepts are identical to biomedical signal processing,which includes the investigation,improvement,and exhibition of images gathered using x-ray,ultrasound,MRI,etc.At the same time,cervical cancer becomes a major reason for increased women’s mortality rate.But cervical cancer is an identified at an earlier stage using regular pap smear images.In this aspect,this paper devises a new biomedical pap smear image classification using cascaded deep forest(BPSIC-CDF)model on Internet of Things(IoT)environment.The BPSIC-CDF technique enables the IoT devices for pap smear image acquisition.In addition,the pre-processing of pap smear images takes place using adaptive weighted mean filtering(AWMF)technique.Moreover,sailfish optimizer with Tsallis entropy(SFO-TE)approach has been implemented for the segmentation of pap smear images.Furthermore,a deep learning based Residual Network(ResNet50)method was executed as a feature extractor and CDF as a classifier to determine the class labels of the input pap smear images.In order to showcase the improved diagnostic outcome of the BPSICCDF technique,a comprehensive set of simulations take place on Herlev database.The experimental results highlighted the betterment of the BPSICCDF technique over the recent state of art techniques interms of different performance measures.

Biomedical Osteosarcoma Image Classification Using Elephant Herd Optimization and Deep Learning

Osteosarcoma is a type of malignant bone tumor that is reported across the globe.Recent advancements in Machine Learning(ML)and Deep Learning(DL)models enable the detection and classification of malignancies in biomedical images.In this regard,the current study introduces a new Biomedical Osteosarcoma Image Classification using Elephant Herd Optimization and Deep Transfer Learning(BOIC-EHODTL)model.The presented BOIC-EHODTL model examines the biomedical images to diagnose distinct kinds of osteosarcoma.At the initial stage,Gabor Filter(GF)is applied as a pre-processing technique to get rid of the noise from images.In addition,Adam optimizer with MixNet model is also employed as a feature extraction technique to generate feature vectors.Then,EHOalgorithm is utilized along with Adaptive Neuro-Fuzzy Classifier(ANFC)model for recognition and categorization of osteosarcoma.EHO algorithm is utilized to fine-tune the parameters involved in ANFC model which in turn helps in accomplishing improved classification results.The design of EHO with ANFC model for classification of osteosarcoma is the novelty of current study.In order to demonstrate the improved performance of BOIC-EHODTL model,a comprehensive comparison was conducted between the proposed and existing models upon benchmark dataset and the results confirmed the better performance of BOIC-EHODTL model over recent methodologies.

Circular Ribbon Antenna Array Design For Imaging Application

Our goal is to develop THz module on chip to visualize bone grinding at the early stage so that arthritis can be visualized and treated early.A critical component of such module is antenna.A compact 4 by 4 beamforming antenna array for biomedical application is presented in this paper.We are proposing a novel antenna which is in the form of a circular ribbon shape with a gold patch.Gold material for the patch is used to enhance its conductivity and to cut down backward radiation.Differential port pin used to increase the bandwidth.Au-posts are finally used for output connection.The proposed antenna operates over the frequency band from 201 GHz to more than 228 GHz.Directivity and gain of the proposed antenna are 13 dB and 7 dB respectively.This makes it applicable for imaging systems because of the frequency band for biomedical imaging.Index Terms-Beamforming antenna,antenna array,Advanced design system(ADS),Biomedical imaging.

Deep Learning Enabled Computer Aided Diagnosis Model for Lung Cancer using Biomedical CT Images

Early detection of lung cancer can help for improving the survival rate of the patients.Biomedical imaging tools such as computed tomography(CT)image was utilized to the proper identification and positioning of lung cancer.The recently developed deep learning(DL)models can be employed for the effectual identification and classification of diseases.This article introduces novel deep learning enabled CAD technique for lung cancer using biomedical CT image,named DLCADLC-BCT technique.The proposed DLCADLC-BCT technique intends for detecting and classifying lung cancer using CT images.The proposed DLCADLC-BCT technique initially uses gray level co-occurrence matrix(GLCM)model for feature extraction.Also,long short term memory(LSTM)model was applied for classifying the existence of lung cancer in the CT images.Moreover,moth swarm optimization(MSO)algorithm is employed to optimally choose the hyperparameters of the LSTM model such as learning rate,batch size,and epoch count.For demonstrating the improved classifier results of the DLCADLC-BCT approach,a set of simulations were executed on benchmark dataset and the outcomes exhibited the supremacy of the DLCADLC-BCT technique over the recent approaches.

Biomedical Image Processing Using FCM Algorithm Based on the Wavelet Transform

An effective processing method for biomedical images and the Fuzzy C-mean (FCM) algorithm based on the wavelet transform are investigated.By using hierarchical wavelet decomposition, an original image could be decomposed into one lower image and several detail images. The segmentation started at the lowest resolution with the FCM clustering algorithm and the texture feature extracted from various sub-bands. With the improvement of the FCM algorithm, FCM alternation frequency was decreased and the accuracy of segmentation was advanced.

Intelligent Deep Learning Based Disease Diagnosis Using Biomedical Tongue Images

The rapid development of biomedical imaging modalities led to its wide application in disease diagnosis.Tongue-based diagnostic procedures are proficient and non-invasive in nature to carry out secondary diagnostic processes ubiquitously.Traditionally,physicians examine the characteristics of tongue prior to decision-making.In this scenario,to get rid of qualitative aspects,tongue images can be quantitatively inspected for which a new disease diagnosis model is proposed.This model can reduce the physical harm made to the patients.Several tongue image analytical methodologies have been proposed earlier.However,there is a need exists to design an intelligent Deep Learning(DL)based disease diagnosis model.With this motivation,the current research article designs an Intelligent DL-basedDisease Diagnosis method using Biomedical Tongue Images called IDLDD-BTI model.The proposed IDLDD-BTI model incorporates Fuzzy-based Adaptive Median Filtering(FADM)technique for noise removal process.Besides,SqueezeNet model is employed as a feature extractor in which the hyperparameters of SqueezeNet are tuned using Oppositional Glowworm Swarm Optimization(OGSO)algorithm.At last,Weighted Extreme Learning Machine(WELM)classifier is applied to allocate proper class labels for input tongue color images.The design of OGSO algorithm for SqueezeNet model shows the novelty of the work.To assess the enhanced diagnostic performance of the presented IDLDD-BTI technique,a series of simulations was conducted on benchmark dataset and the results were examined in terms of several measures.The resultant experimental values highlighted the supremacy of IDLDD-BTI model over other state-of-the-art methods.

Metaheuristic with Deep Learning Enabled Biomedical Bone Age Assessment and Classification Model

The skeletal bone age assessment(BAA)was extremely implemented in development prediction and auxiliary analysis of medicinal issues.X-ray images of hands were detected from the estimation of bone age,whereas the ossification centers of epiphysis and carpal bones are important regions.The typical skeletal BAA approaches remove these regions for predicting the bone age,however,few of them attain suitable efficacy or accuracy.Automatic BAA techniques with deep learning(DL)methods are reached the leading efficiency on manual and typical approaches.Therefore,this study introduces an intellectual skeletal bone age assessment and classification with the use of metaheuristic with deep learning(ISBAAC-MDL)model.The presented ISBAAC-MDL technique majorly focuses on the identification of bone age prediction and classification process.To attain this,the presented ISBAAC-MDL model derives a mask Region-related Convolutional Neural Network(Mask-RCNN)with MobileNet as baseline model to extract features.Followed by,the whale optimization algorithm(WOA)is implemented for hyperparameter tuning of the MobileNet method.At last,Deep Feed-Forward Module(DFFM)based age prediction and Radial Basis Function Neural Network(RBFNN)based stage classification approach is utilized.The experimental evaluation of the ISBAAC-MDL model is tested using benchmark dataset and the outcomes are assessed over distinct factors.The experimental outcomes reported the better performances of the ISBAACMDL model over recent approaches with maximum accuracy of 0.9920.

Intelligent Deep Transfer Learning Based Malaria Parasite Detection andClassification Model Using Biomedical Image

Malaria is a severe disease caused by Plasmodium parasites,which can be detected through blood smear images.The early identification of the disease can effectively reduce the severity rate.Deep learning(DL)models can be widely employed to analyze biomedical images,thereby minimizing the misclassification rate.With this objective,this study developed an intelligent deep-transfer-learning-based malaria parasite detection and classification(IDTL-MPDC)model on blood smear images.The proposed IDTL-MPDC technique aims to effectively determine the presence of malarial parasites in blood smear images.In addition,the IDTL-MPDC technique derives median filtering(MF)as a pre-processing step.In addition,a residual neural network(Res2Net)model was employed for the extraction of feature vectors,and its hyperparameters were optimally adjusted using the differential evolution(DE)algorithm.The k-nearest neighbor(KNN)classifier was used to assign appropriate classes to the blood smear images.The optimal selection of Res2Net hyperparameters by the DE model helps achieve enhanced classification outcomes.A wide range of simulation analyses of the IDTL-MPDC technique are carried out using a benchmark dataset,and its performance seems to be highly accurate(95.86%),highly sensitive(95.82%),highly specific(95.98%),with a high F1 score(95.69%),and high precision(95.86%),and it has been proven to be better than the other existing methods.

A Robust Non-Blind Watermarking for Biomedical Images Based on Chaos

The advent of the Internet in these last years encouraged a considerable traffic of digital images. In the sanitary field, precisely in telemedicine branch, medical images play a very important role for therapeutic diagnoses. Thus, it is necessary to protect medical images data before transmission over the network to preserve their security and prevent unauthorized access. In this paper, a secure algorithm for biomedical images encryption scheme based on the combination of watermarking technique and chaotic function is proposed. In the proposed method, to achieve high security level performances, a non-blind hybrid watermarking technique with audio signal, Discrete Wavelet Transform is used;smoothness is also used as selected criteria;the iterations obtained by the chaotic sequences are essential and allow a good realization of the encryption process. One of the main advantages of chaos-based encryption schemes is the generation of a large number of key spaces to resist brute force attacks from the encryption algorithm. The experimental results presented in this paper attest to the invisibility and robustness of the proposed algorithm combining watermarking and chaos-based encryption.

Multimodal compression applied to biomedical data

In this paper, we introduce a novel approach to compress jointly a medical image and a multichannel bio-signals (e.g. ECG, EEG). This technique is based on the idea of Multimodal Compression (MC) which requires only one codec instead of multiple codecs. Objectively, biosignal samples are merged in the spatial domain of the image using a specific mixing function. Afterwards, the whole mixture is compressed using JPEG 2000. The spatial mixing function inserts samples in low-frequency regions, defined using a set of operations, including down-sampling, interpolation, and quad-tree decomposition. The decoding is achieved by inverting the process using a separation function. Results show that this technique allows better performances in terms of Compression Ratio (CR) compared to approaches which encode separately modalities. The reconstruction quality is evaluated on a set of test data using the PSNR (Peak Signal Noise Ratio) and the PRD (Percent Root Mean Square Difference), respectively for the image and biosignals.

Automated Colonic Polyp Detection and Classification Enabled Northern Goshawk Optimization with Deep Learning

The major mortality factor relevant to the intestinal tract is the growth of tumorous cells(polyps)in various parts.More specifically,colonic polyps have a high rate and are recognized as a precursor of colon cancer growth.Endoscopy is the conventional technique for detecting colon polyps,and considerable research has proved that automated diagnosis of image regions that might have polyps within the colon might be used to help experts for decreasing the polyp miss rate.The automated diagnosis of polyps in a computer-aided diagnosis(CAD)method is implemented using statistical analysis.Nowadays,Deep Learning,particularly throughConvolution Neural networks(CNN),is broadly employed to allowthe extraction of representative features.This manuscript devises a new Northern Goshawk Optimization with Transfer Learning Model for Colonic Polyp Detection and Classification(NGOTL-CPDC)model.The NGOTL-CPDC technique aims to investigate endoscopic images for automated colonic polyp detection.To accomplish this,the NGOTL-CPDC technique comprises of adaptive bilateral filtering(ABF)technique as a noise removal process and image pre-processing step.Besides,the NGOTL-CPDC model applies the Faster SqueezeNet model for feature extraction purposes in which the hyperparameter tuning process is performed using the NGO optimizer.Finally,the fuzzy Hopfield neural network(FHNN)method can be employed for colonic poly detection and classification.A widespread simulation analysis is carried out to ensure the improved outcomes of the NGOTL-CPDC model.The comparison study demonstrates the enhancements of the NGOTL-CPDC model on the colonic polyp classification process on medical test images.

Optimal Deep Transfer Learning Based Colorectal Cancer Detection and Classification Model

Colorectal carcinoma(CRC)is one such dispersed cancer globally and also prominent one in causing cancer-based death.Conventionally,pathologists execute CRC diagnosis through visible scrutinizing under the microscope the resected tissue samples,stained and fixed through Haematoxylin and Eosin(H&E).The advancement of graphical processing systems has resulted in high potentiality for deep learning(DL)techniques in interpretating visual anatomy from high resolution medical images.This study develops a slime mould algorithm with deep transfer learning enabled colorectal cancer detection and classification(SMADTL-CCDC)algorithm.The presented SMADTL-CCDC technique intends to appropriately recognize the occurrence of colorectal cancer.To accomplish this,the SMADTLCCDC model initially undergoes pre-processing to improve the input image quality.In addition,a dense-EfficientNet technique was employed to extract feature vectors from the pre-processed images.Moreover,SMA with Discrete Hopfield neural network(DHNN)method was applied for the recognition and classification of colorectal cancer.The utilization of SMA assists in appropriately selecting the parameters involved in the DHNN approach.A wide range of experiments was implemented on benchmark datasets to assess the classification performance.A comprehensive comparative study highlighted the better performance of the SMADTL-CDC model over the recent approaches.