Optimal Sparse Autoencoder Based Sleep Stage Classification Using Biomedical Signals

The recently developed machine learning(ML)models have the ability to obtain high detection rate using biomedical signals.Therefore,this article develops an Optimal Sparse Autoencoder based Sleep Stage Classification Model on Electroencephalography(EEG)Biomedical Signals,named OSAE-SSCEEG technique.The major intention of the OSAE-SSCEEG technique is tofind the sleep stage disorders using the EEG biomedical signals.The OSAE-SSCEEG technique primarily undergoes preprocessing using min-max data normalization approach.Moreover,the classification of sleep stages takes place using the Sparse Autoencoder with Smoothed Regularization(SAE-SR)with softmax(SM)approach.Finally,the parameter optimization of the SAE-SR technique is carried out by the use of Coyote Optimization Algorithm(COA)and it leads to boosted classification efficiency.In order to ensure the enhanced performance of the OSAE-SSCEEG technique,a wide ranging simulation analysis is performed and the obtained results demonstrate the betterment of the OSAE-SSCEEG tech-nique over the recent methods.

A robust extraction algorithm for biomedical signals from noisy mixtures

Blind source extraction （BSE） is widely used to solve signal mixture problems where there are only a few desired signals. To improve signal extraction performance and expand its application, we develop an adaptive BSE algorithm with an additive noise model. We first present an improved normalized kurtosis as an objective function, which caters for the effect of noise. By combining the objective function and Lagrange multiplier method, we further propose a robust algorithm that can extract the desired signal as the first output signal. Simulations on both synthetic and real biomedical signals demonstrate that such combination improves the extrac- tion performance and has better robustness to the estimation error of normalized kurtosis value in the presence of noise.

Intelligent Biomedical Electrocardiogram Signal Processing for Cardiovascular Disease Diagnosis

Automatic biomedical signal recognition is an important processfor several disease diagnoses. Particularly, Electrocardiogram (ECG) is commonly used to identify cardiovascular diseases. The professionals can determine the existence of cardiovascular diseases using the morphological patternsof the ECG signals. In order to raise the diagnostic accuracy and reduce thediagnostic time, automated computer aided diagnosis model is necessary. Withthe advancements of artificial intelligence (AI) techniques, large quantity ofbiomedical datasets can be easily examined for decision making. In this aspect,this paper presents an intelligent biomedical ECG signal processing (IBECGSP) technique for CVD diagnosis. The proposed IBECG-SP technique examines the ECG signals for decision making. In addition, gated recurrent unit(GRU) model is used for the feature extraction of the ECG signals. Moreover,earthworm optimization (EWO) algorithm is utilized to optimally tune thehyperparameters of the GRU model. Lastly, softmax classifier is employedto allot appropriate class labels to the applied ECG signals. For examiningthe enhanced outcomes of the proposed IBECG-SP technique, an extensivesimulation analysis take place on the PTB-XL database. The experimentalresults portrayed the supremacy of the IBECG-SP technique over the recentstate of art techniques.

Compact Bat Algorithm with Deep Learning Model for Biomedical EEG EyeState Classification

Electroencephalography(EEG)eye state classification becomes an essential tool to identify the cognitive state of humans.It can be used in several fields such as motor imagery recognition,drug effect detection,emotion categorization,seizure detection,etc.With the latest advances in deep learning(DL)models,it is possible to design an accurate and prompt EEG EyeState classification problem.In this view,this study presents a novel compact bat algorithm with deep learning model for biomedical EEG EyeState classification(CBADL-BEESC)model.The major intention of the CBADL-BEESC technique aims to categorize the presence of EEG EyeState.The CBADL-BEESC model performs feature extraction using the ALexNet model which helps to produce useful feature vectors.In addition,extreme learning machine autoencoder(ELM-AE)model is applied to classify the EEG signals and the parameter tuning of the ELM-AE model is performed using CBA.The experimental result analysis of the CBADL-BEESC model is carried out on benchmark results and the comparative outcome reported the supremacy of the CBADL-BEESC model over the recent methods.

Automated Deep Learning Based Cardiovascular Disease Diagnosis Using ECG Signals

Automated biomedical signal processing becomes an essential process to determine the indicators of diseased states.At the same time,latest develop-ments of artificial intelligence(AI)techniques have the ability to manage and ana-lyzing massive amounts of biomedical datasets results in clinical decisions and real time applications.They can be employed for medical imaging;however,the 1D biomedical signal recognition process is still needing to be improved.Electrocardiogram(ECG)is one of the widely used 1-dimensional biomedical sig-nals,which is used to diagnose cardiovascular diseases.Computer assisted diag-nostic modelsfind it difficult to automatically classify the 1D ECG signals owing to time-varying dynamics and diverse profiles of ECG signals.To resolve these issues,this study designs automated deep learning based 1D biomedical ECG sig-nal recognition for cardiovascular disease diagnosis(DLECG-CVD)model.The DLECG-CVD model involves different stages of operations such as pre-proces-sing,feature extraction,hyperparameter tuning,and classification.At the initial stage,data pre-processing takes place to convert the ECG report to valuable data and transform it into a compatible format for further processing.In addition,deep belief network(DBN)model is applied to derive a set of feature vectors.Besides,improved swallow swarm optimization(ISSO)algorithm is used for the hyper-parameter tuning of the DBN model.Lastly,extreme gradient boosting(XGBoost)classifier is employed to allocate proper class labels to the test ECG signals.In order to verify the improved diagnostic performance of the DLECG-CVD model,a set of simulations is carried out on the benchmark PTB-XL dataset.A detailed comparative study highlighted the betterment of the DLECG-CVD model interms of accuracy,sensitivity,specificity,kappa,Mathew correlation coefficient,and Hamming loss.

Multimodal compression applied to biomedical data

In this paper, we introduce a novel approach to compress jointly a medical image and a multichannel bio-signals (e.g. ECG, EEG). This technique is based on the idea of Multimodal Compression (MC) which requires only one codec instead of multiple codecs. Objectively, biosignal samples are merged in the spatial domain of the image using a specific mixing function. Afterwards, the whole mixture is compressed using JPEG 2000. The spatial mixing function inserts samples in low-frequency regions, defined using a set of operations, including down-sampling, interpolation, and quad-tree decomposition. The decoding is achieved by inverting the process using a separation function. Results show that this technique allows better performances in terms of Compression Ratio (CR) compared to approaches which encode separately modalities. The reconstruction quality is evaluated on a set of test data using the PSNR (Peak Signal Noise Ratio) and the PRD (Percent Root Mean Square Difference), respectively for the image and biosignals.

Transfer Learning Model to Indicate Heart Health Status Using Phonocardiogram

The early diagnosis of pre-existing coronary disorders helps to control complications such as pulmonary hypertension,irregular cardiac functioning,and heart failure.Machine-based learning of heart sound is an efficient technology which can help minimize the workload of manual auscultation by automatically identifying irregular cardiac sounds.Phonocardiogram(PCG)and electrocardiogram(ECG)waveforms provide the much-needed information for the diagnosis of these diseases.In this work,the researchers have converted the heart sound signal into its corresponding repeating pattern-based spectrogram.PhysioNet 2016 and PASCAL 2011 have been taken as the benchmark datasets to perform experimentation.The existing models,viz.MobileNet,Xception,Visual Geometry Group(VGG16),ResNet,DenseNet,and InceptionV3 of Transfer Learning have been used for classifying the heart sound signals as normal and abnormal.For PhysioNet 2016,DenseNet has outperformed its peer models with an accuracy of 89.04 percent,whereas for PASCAL 2011,VGG has outperformed its peer approaches with an accuracy of 92.96 percent.

A Feature Extraction Method for scRNA-seq Processing and Its Application on COVID-19 Data Analysis

Single-cell RNA-sequencing(scRNA-seq)is a rapidly increasing research area in biomed-ical signal processing.However,the high complexity of single-cell data makes efficient and accurate analysis difficult.To improve the performance of single-cell RNA data processing,two single-cell features calculation method and corresponding dual-input neural network structures are proposed.In this feature extraction and fusion scheme,the features at the cluster level are extracted by hier-archical clustering and differential gene analysis,and the features at the cell level are extracted by the calculation of gene frequency and cross cell frequency.Our experiments on COVID-19 data demonstrate that the combined use of these two feature achieves great results and high robustness for classification tasks.

Noisy component extraction with reference

Blind source extraction （BSE） is particularly at- tractive to solve blind signal mixture problems where only a few source signals are desired. Many existing BSE methods do not take into account the existence of noise and can only work well in noise-free environments. In practice, the desired signal is often contaminated by additional noise. Therefore, we try to tackle the problem of noisy component extraction. The reference signal carries enough prior information to dis- tinguish the desired signal from signal mixtures. According to the useful properties of Gaussian moments, we incorporate the reference signal into a negentropy objective function so as to guide the extraction process and develop an improved BSE method. Extensive computer simulations demonstrate its validity in the process of revealing the underlying desired signal.